Title: Protein synthesis in lobster walking leg nerves
Abstract: 1. When isolated bundles of nerve fibers from the walking legs of lobster were incubated in a mixture of C14-labeled amino acids (C14-aa) radioactivity was found in both the trichloroacetic acid soluble part and in the TCA precipitate. 2. Chloramphenicol and cycloheximide inhibited the incorporation of radioactivity into the TCA precipitate. 3. Pretreatment of nerves for 30 min prior to incubation in the C14-aa with a variety of drugs inhibiting cholinesterase did not change the amount of radio-activity in the TCA soluble fraction but increased the rate of incorporation into the TCA precipitate by at least 90%. 4. If paraoxon was present in the C14-aa during the incubation, the amount of radioactivity in the TCA soluble fraction decreased and inhibition of C14-aa incorporation into the TCA precipitate was almost complete.
Publication Year: 1971
Publication Date: 1971-02-01
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 16
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