Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2028234551', 'doi': 'https://doi.org/10.1007/s12016-007-8015-4', 'title': 'B-Cell Depletion and Repopulation in Autoimmune Diseases', 'display_name': 'B-Cell Depletion and Repopulation in Autoimmune Diseases', 'publication_year': 2007, 'publication_date': '2007-09-06', 'ids': {'openalex': 'https://openalex.org/W2028234551', 'doi': 'https://doi.org/10.1007/s12016-007-8015-4', 'mag': '2028234551', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18270858'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s12016-007-8015-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S120080025', 'display_name': 'Clinical Reviews in Allergy & Immunology', 'issn_l': '1080-0549', 'issn': ['1080-0549', '1559-0267'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087088946', 'display_name': 'Jacques‐Olivier Pers', 'orcid': 'https://orcid.org/0000-0001-7287-5541'}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jacques-Olivier Pers', 'raw_affiliation_strings': ['Department of Immunopathology, Brest University Medical School, Brest, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunopathology, Brest University Medical School, Brest, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091390401', 'display_name': 'Capucine Daridon', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Capucine Daridon', 'raw_affiliation_strings': ['Department of Immunopathology, Brest University Medical School, Brest, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunopathology, Brest University Medical School, Brest, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055851200', 'display_name': 'Boutahar Bendaoud', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Boutahar Bendaoud', 'raw_affiliation_strings': ['Department of Immunopathology, Brest University Medical School, Brest, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunopathology, Brest University Medical School, Brest, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026084954', 'display_name': 'Valérie Devauchelle', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Valérie Devauchelle', 'raw_affiliation_strings': ['Department of Immunopathology, Brest University Medical School, Brest, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunopathology, Brest University Medical School, Brest, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102017784', 'display_name': 'Christian Berthou', 'orcid': 'https://orcid.org/0000-0003-1246-5852'}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Christian Berthou', 'raw_affiliation_strings': ['Department of Immunopathology, Brest University Medical School, Brest, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunopathology, Brest University Medical School, Brest, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032316254', 'display_name': 'Alain Saraux', 'orcid': 'https://orcid.org/0000-0002-8454-7067'}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Alain Saraux', 'raw_affiliation_strings': ['Department of Immunopathology, Brest University Medical School, Brest, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Immunopathology, Brest University Medical School, Brest, France', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5014705464', 'display_name': 'Pierre Youinou', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210132604', 'display_name': 'Centre Hospitalier Régional Universitaire de Brest', 'ror': 'https://ror.org/03evbwn87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210105774', 'https://openalex.org/I4210132604', 'https://openalex.org/I4210161065']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Pierre Youinou', 'raw_affiliation_strings': ['Laboratory of Immunology, Brest University Medical School Hospital, BP824, 29609, Brest, France'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology, Brest University Medical School Hospital, BP824, 29609, Brest, France', 'institution_ids': ['https://openalex.org/I4210132604']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5014705464'], 'corresponding_institution_ids': ['https://openalex.org/I4210132604'], 'apc_list': {'value': 3690, 'currency': 'EUR', 'value_usd': 4790, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.652, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 49, 'citation_normalized_percentile': {'value': 0.53262, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '34', 'issue': '1', 'first_page': '50', 'last_page': '55'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11521', 'display_name': "Diagnosis and Management of Sjögren's Syndrome", 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11521', 'display_name': "Diagnosis and Management of Sjögren's Syndrome", 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10308', 'display_name': 'Systemic Lupus Erythematosus and Antiphospholipid Syndrome', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'Regulatory T Cell Development and Function', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/b-lymphocyte-depletion', 'display_name': 'B Lymphocyte Depletion', 'score': 0.609252}], 'concepts': [{'id': 'https://openalex.org/C2780653079', 'wikidata': 'https://www.wikidata.org/wiki/Q412323', 'display_name': 'Rituximab', 'level': 3, 'score': 0.8958448}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.7641059}, {'id': 'https://openalex.org/C2777575956', 'wikidata': 'https://www.wikidata.org/wiki/Q187255', 'display_name': 'Rheumatoid arthritis', 'level': 2, 'score': 0.7340708}, {'id': 'https://openalex.org/C18031839', 'wikidata': 'https://www.wikidata.org/wiki/Q5009796', 'display_name': 'CD20', 'level': 3, 'score': 0.700863}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.63576674}, {'id': 'https://openalex.org/C2778453870', 'wikidata': 'https://www.wikidata.org/wiki/Q188930', 'display_name': 'B cell', 'level': 3, 'score': 0.6119777}, {'id': 'https://openalex.org/C2780130043', 'wikidata': 'https://www.wikidata.org/wiki/Q192360', 'display_name': 'Autoimmunity', 'level': 3, 'score': 0.5908853}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.46188137}, {'id': 'https://openalex.org/C51785407', 'wikidata': 'https://www.wikidata.org/wiki/Q2627568', 'display_name': 'Effector', 'level': 2, 'score': 0.42774475}, {'id': 'https://openalex.org/C163864487', 'wikidata': 'https://www.wikidata.org/wiki/Q6901461', 'display_name': 'Monoclonal', 'level': 4, 'score': 0.4145}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.3597687}], 'mesh': [{'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001402', 'descriptor_name': 'B-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D001402', 'descriptor_name': 'B-Lymphocytes', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D007155', 'descriptor_name': 'Immunologic Factors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D008212', 'descriptor_name': 'Lymphocyte Depletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058846', 'descriptor_name': 'Antibodies, Monoclonal, Murine-Derived', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D001402', 'descriptor_name': 'B-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007155', 'descriptor_name': 'Immunologic Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000069283', 'descriptor_name': 'Rituximab', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012859', 'descriptor_name': "Sjogren's Syndrome", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012859', 'descriptor_name': "Sjogren's Syndrome", 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D012859', 'descriptor_name': "Sjogren's Syndrome", 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D012859', 'descriptor_name': "Sjogren's Syndrome", 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s12016-007-8015-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S120080025', 'display_name': 'Clinical Reviews in Allergy & Immunology', 'issn_l': '1080-0549', 'issn': ['1080-0549', '1559-0267'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18270858', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.82, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W1576993812', 'https://openalex.org/W1642392901', 'https://openalex.org/W1968108602', 'https://openalex.org/W1968889356', 'https://openalex.org/W1979336667', 'https://openalex.org/W1998618256', 'https://openalex.org/W2017709470', 'https://openalex.org/W2024235155', 'https://openalex.org/W2042123531', 'https://openalex.org/W2044360617', 'https://openalex.org/W2045594979', 'https://openalex.org/W2051022408', 'https://openalex.org/W2051649686', 'https://openalex.org/W2053838509', 'https://openalex.org/W2057541619', 'https://openalex.org/W206701898', 'https://openalex.org/W2071131425', 'https://openalex.org/W2074258431', 'https://openalex.org/W2077286174', 'https://openalex.org/W2084547554', 'https://openalex.org/W2099704507', 'https://openalex.org/W2099868898', 'https://openalex.org/W2105594762', 'https://openalex.org/W2108787411', 'https://openalex.org/W2118994799', 'https://openalex.org/W2137157133', 'https://openalex.org/W2146764660', 'https://openalex.org/W2170938637', 'https://openalex.org/W239286793', 'https://openalex.org/W2438597677'], 'related_works': ['https://openalex.org/W3116220978', 'https://openalex.org/W2413577486', 'https://openalex.org/W2294463202', 'https://openalex.org/W2182701989', 'https://openalex.org/W2126167931', 'https://openalex.org/W2049439131', 'https://openalex.org/W2039226259', 'https://openalex.org/W2017866273', 'https://openalex.org/W2001794114', 'https://openalex.org/W1969480819'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2028234551', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-09-16T10:02:29.552649', 'created_date': '2016-06-24'}