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'have': [157], 'read': [158], 'accept': [160], 'Wiley': [162], 'Online': [163], 'Library': [164], 'UseShareable': [169], 'LinkUse': [170], 'link': [172], 'a': [176, 191, 240, 817, 946, 981, 1041, 1102, 1108, 1162, 1208, 1480, 2127, 2647, 2687], 'article': [181], 'with': [182, 500, 557, 627, 816, 1488, 1961, 2224, 2384, 2952, 3286, 3388, 3525], 'your': [183], 'friends': [184], 'colleagues.': [186], 'Learn': [187], 'more.Copy': [188], 'URL': [189], 'Share': [190], 'linkShare': [192], 'onEmailFacebookTwitterLinkedInRedditWechat': [193], 'REFERENCES': [194], '1': [195, 823, 885, 2056, 2712, 2876, 2943], 'Mayne': [196], 'R,': [197, 403, 973, 1176, 1367, 1464, 1503, 1764, 1833, 2113, 2322, 2361, 3428], 'Brewton': [198], 'RG.': [199], 'Extracellular': [200], 'matrix': [201, 375, 449, 483, 545, 585, 689, 745, 886], 'cartilage:': [203, 445, 1722], 'collagen.': [204], 'In:': [205, 232, 280, 309, 1248], 'JF': [206, 647, 1249], 'Woessner,': [207], 'HowellDS,': [208], 'editors.': [209, 287, 316, 1256], 'cartilage': [211, 292, 321, 489, 519, 591, 813, 861, 1085, 1184, 1213, 1243, 1258, 1355, 1552, 1690, 2472, 2682, 2722, 2775, 2918, 3048, 3124, 3252, 3391, 3495, 3520, 3549], 'degradation:': [212, 1259], 'basic': [213, 1260], 'clinical': [215, 1262], 'aspects.': [216, 1263], 'York:': [218, 295, 324, 1265], 'Marcel': [219, 1266], 'Dekker;': [220, 1267], '1993.': [221, 1268], '81–108.': [223], '2': [224, 3249], 'Poole': [225, 514], 'AR.': [226, 515], 'Cartilage': [227, 1088, 1359, 1676, 1778, 2270, 3158, 3191, 3296, 3460], 'health': [229], 'disease.': [231], 'WJ': [233], 'Koopman,': [234], 'editor.': [235], 'allied': [238], 'conditions:': [239], 'textbook': [241], 'rheumatology.': [243], 'Baltimore:': [244], 'Williams': [245, 929], 'Wilkins;': [247], '1997.': [248], '255–308.': [250], '3': [251, 587, 2035, 2914], 'Hardingham': [252], 'TE,': [253, 2075, 2276], 'Fosang': [254, 358, 833], 'AJ.': [255], 'Proteoglycans:': [256], 'many': [257, 260], 'forms': [258], 'functions.': [261], 'FASEB': [262, 3321, 3347], 'J': [263, 389, 420, 460, 660, 695, 757, 778, 864, 914, 955, 1019, 1056, 1190, 1233, 1251, 1628, 1727, 1822, 1851, 1906, 1940, 1969, 2102, 2165, 2345, 2659, 2693, 2796, 2921, 3014, 3092, 3220, 3322, 3348, 3398, 3531], '1992;': [264, 596, 1404, 2849], '6:': [265, 3462], '861–70.': [266], 'Heinegard': [268], 'D,': [269, 338, 874, 1766, 1788, 1981, 2535, 3030, 3199, 3354], 'Saxne': [270], 'T,': [271, 470, 732, 1064, 1094, 1118, 1505, 1948, 2146, 2601], 'Lorenzo': [272], 'P.': [273], 'Noncollagenous': [274], 'proteins:': [275], 'glycoproteins': [276], 'related': [278], 'molecules.': [279], 'MJ': [281, 310], 'Seibel,': [282, 311], 'SP': [283, 312], 'Robins,': [284, 313], 'JP': [285, 314], 'Bilezekian,': [286, 315], 'Dynamics': [288, 317], 'bone': [290, 319, 1215, 3003, 3036, 3050, 3085, 3207], 'metabolism.': [293, 322], 'Academic': [296, 325], 'Press;': [297, 326], '1999.': [298, 327], '59–69.': [300], '5': [301], 'Akesson': [302], 'K.': [303, 1070], 'Osteoarthritis': [304, 1087, 1358, 1675, 1777, 2269, 3157, 3190, 3295, 3459], 'degenerative': [306], 'spine': [307], 'pathologies.': [308], '637–48.': [329], '6': [330], 'Radin': [331], 'EL,': [332, 3235], 'Burr': [333], 'DB,': [334], 'Caterson': [335, 356, 879], 'B,': [336, 357, 768, 880, 1741, 2359, 3373], 'Fyhrie': [337], 'Brown': [339], 'TD,': [340], 'Boyd': [341], 'RD.': [342, 3281], 'Mechanical': [343], 'determinants': [344], 'osteoarthrosis.': [346], 'Semin': [347, 1311], 'Rheum': [349, 503, 528, 563, 633, 722, 828, 1111, 1143, 1293, 1313, 1403, 1449, 1518, 1555, 1592, 1651, 1692, 1804, 2016, 2061, 2140, 2200, 2310, 2436, 2475, 2509, 2847, 2891, 2964, 2990, 3137, 3269, 3366, 3500], '1991;': [350], '21:': [351], '12–21.': [352], '7': [353], 'Hughes': [354, 871], 'CE,': [355, 872], 'AJ,': [359, 834, 1858], 'Roughley': [360], 'PJ,': [361, 678, 838, 1710, 2633], 'Mort': [362], 'JS.': [363], 'Monoclonal': [364], 'antibodies': [365], 'that': [366, 820, 938, 1438], 'specifically': [367], 'recognize': [368], 'neoepitope': [369], 'sequences': [370], 'generated': [371], "'aggrecanase'": [373, 897], 'metalloproteinase': [376, 450, 586, 651, 653, 746, 825, 887, 2037], 'cleavage': [377, 409, 803, 939], 'aggrecan:': [379, 936], 'application': [380], 'catabolism': [382, 934], 'situ': [384], 'vitro.': [387], 'Biochem': [388, 863, 913, 1189, 1232, 2820], '1995;': [390, 565, 958, 1294, 2558, 2594, 2799, 3401, 3416], '305:': [391], '799–804.': [392], '8': [393], 'Billinghurst': [394, 787], 'RC,': [395, 788, 1917], 'Dahlberg': [396, 785], 'L,': [397, 786, 1602, 1743, 2571], 'Ionescu': [398, 477, 510, 795], 'M,': [399, 478, 511, 572, 738, 796, 1409, 1604, 1704, 1739, 1768, 2452, 2539, 3424, 3506, 3540], 'Reiner': [400], 'A,': [401, 578, 876, 1737, 1923, 2028, 2320, 2355, 3508, 3510], 'Bourne': [402], 'Rorabeck': [404], 'C,': [405, 766, 1572, 1598, 1735, 2324, 2573, 2934, 3512], 'et': [406, 439, 479, 581, 679, 739, 797, 845, 881, 931, 974, 1006, 1376, 1467, 1510, 1573, 1609, 1713, 1886, 1924, 2078, 2120, 2251, 2287, 2364, 2453, 2492, 2544, 2574, 2638, 3384, 3433], 'al.': [407, 440, 480, 582, 680, 740, 798, 846, 882, 932, 975, 1007, 1377, 1468, 1511, 1574, 1610, 1714, 1887, 1925, 2079, 2121, 2252, 2288, 2365, 2454, 2493, 2545, 2575, 2639, 3385, 3434], 'Enhanced': [408], 'type': [411, 684, 807, 884, 1132, 1391, 1617, 2615, 2942], 'II': [412, 685, 808, 1618, 2616], 'collagen': [413, 492, 809, 1074, 1672, 1838, 2300, 3479], 'collagenases': [415], 'osteoarthritic': [417, 590, 658, 693, 754, 812, 1084, 1140, 1384, 1751, 2002, 2187, 2426, 2842, 2866, 2950], 'articular': [418, 1137, 1242, 1386, 1626, 1689, 1957, 2157, 2267, 2381, 2721, 2794, 2817, 2844, 2917, 3008, 3076, 3218, 3251], 'cartilage.': [419, 659, 694, 755, 1141, 1754, 2795, 2818, 2845, 3219], 'Clin': [421, 461, 661, 696, 1629, 1694, 1728, 2231, 3553], 'Invest': [422, 462, 595, 662, 697, 1630, 1729], '1997;': [423, 463, 723, 759, 1089, 1113, 1360, 1631, 1730, 2104, 2476, 2528, 2661, 2695, 2741, 2822, 3138, 3159, 3225, 3270, 3323, 3349, 3555], '99:': [424, 1632, 1731], '1534–45.': [425], 'Lark': [427, 919, 1878], 'MW,': [428, 920, 1879], 'Bayne': [429], 'EK,': [430], 'Flanagan': [431], 'J,': [432, 641, 926, 1174, 1178, 1196, 1202, 1365, 1369, 1411, 1566, 1608, 1712, 1950, 1977, 2150, 3105], 'Harper': [433], 'CF,': [434], 'Hoerrner': [435], 'LA,': [436, 1528], 'Hutchinson': [437], 'NI,': [438], 'Aggrecan': [441], 'degradation': [442], 'human': [444, 657, 692, 753, 776, 1083, 1163, 1385, 1486, 1720, 1817, 2001, 2186, 2266, 2297, 2380, 2500, 2643, 2843, 2916, 2949, 3002, 3122, 3206], 'evidence': [446, 937], 'both': [448], 'aggrecanase': [452, 853, 1014], 'activity': [453, 687, 1545, 1718, 1747, 2123], 'normal,': [455], 'osteoarthritic,': [456], 'rheumatoid': [458, 560, 630, 1157, 1290, 1489, 2226, 2307, 2780], 'joints.': [459], '100:': [464], '93–106.': [465], '10': [466], 'Ishiguro': [467], 'N,': [468, 734, 2172, 2396, 3070], 'Ito': [469, 471, 3467], 'H,': [472, 474, 476, 513, 736, 844, 878, 2533, 2565], 'Iwata': [473], 'Jugessur': [475, 512], 'Relationship': [481], 'metalloproteinases': [484, 546, 617], 'their': [486, 548, 3345], 'inhibitors': [487, 2498], 'proteoglycan': [490, 2374, 2738, 3253, 3264], 'turnover:': [493], 'analyses': [494], 'synovial': [496, 623, 1158, 2220, 2427, 2501], 'fluid': [497, 2221], 'from': [498, 555, 625, 691, 1015, 1187, 1330, 1750, 1819, 2522, 2723, 3184, 3451], 'patients': [499, 556, 626, 2223], 'osteoarthritis.': [501, 526, 1357, 1776, 1802, 3156], '1999;': [504, 529, 990, 1022, 1059, 1144, 1336, 1451, 1519, 1557, 1677, 1697, 1759, 1779, 1870, 2017, 2167, 2201, 2391, 2437, 2510, 2784, 3061, 3367], '42:': [505, 530, 1145, 1520, 2018, 2202, 2438, 2511, 3368], '129–36.': [506], '11': [507], 'Lohmander': [508], 'LS,': [509], 'Changes': [516], 'joint': [518, 1309, 2520, 3182], 'aggrecan': [520, 892, 3439], 'after': [521], 'knee': [522, 3181, 3524], 'injury': [523], '534–44.': [531], '12': [532], 'Hembry': [533, 1175], 'RM,': [534, 1636, 2998], 'Bagga': [535], 'MR,': [536], 'Reynolds': [537], 'JJ,': [538, 1921], 'Hamblen': [539], 'DL.': [540], 'Immunolocalisation': [541], 'studies': [542], 'on': [543, 907, 1615, 2262, 2373, 2471, 2717, 2793, 3044, 3211, 3263], 'six': [544], 'inhibitors,': [549], 'TIMP-1': [550, 2334], 'TIMP-2,': [552], 'synovia': [554], 'osteo-': [558], 'arthritis.': [561, 631, 1291, 1490, 2138, 2781], 'Ann': [562, 1110, 1448, 1554, 2846, 3481], 'Dis': [564, 1112, 1450, 1556, 1693, 2848], '54:': [566], '25–32.': [567], '13': [568, 3043], 'Okada': [569], 'Y,': [570, 1120, 3542], 'Shinmei': [571], 'Tanaka': [573], 'O,': [574, 3466, 3514], 'Naka': [575], 'K,': [576, 728, 836, 1066, 1786, 1810, 2403, 3377], 'Kimura': [577, 927], 'Nakanishi': [579], 'I,': [580, 969, 995, 2208], 'Localization': [583], '(stromelysin)': [588], 'synovium.': [593, 1188], 'Lab': [594], '66:': [597, 1760], '680–90.': [598], '14': [599], 'Clark': [600, 2281], 'IM,': [601, 2282], 'Powell': [602], 'LK,': [603], 'Ramsey': [604], 'S,': [605, 711, 730, 1029, 1375, 1784, 1812, 2115, 2148, 2567, 2569, 2670, 2854, 2974, 3302, 3328, 3383, 3468, 3544], 'Hazleman': [606], 'BL,': [607], 'Cawston': [608, 2074, 2275], 'TE.': [609], 'measurement': [611], 'collagenase,': [613, 1221], 'tissue': [614, 2299, 2753], 'inhibitor': [615, 654, 819, 2129], '(TIMP),': [618], 'collagenase–TIMP': [620], 'complex': [621], 'fluids': [624], '1993;': [634, 3297], '36:': [635], '372–9.': [636], '15': [637], 'Dean': [638, 3276], 'DD,': [639, 2242, 3277], 'Martel-Pelletier': [640, 1364, 1565, 1976, 2181, 2406, 2863, 2937, 3108], 'Pelletier': [642, 1985, 2177, 2400, 2855, 2931, 3102], 'JP,': [643, 1562], 'Howell': [644, 3278], 'DS,': [645, 3279], 'Woessner': [646, 1250], 'Jr.': [648], 'Evidence': [649], 'imbalance': [655], '1989;': [663], '84:': [664], '678–85.': [665], '16': [666], 'Mitchell': [667], 'PG,': [668], 'Magna': [669], 'HA,': [670], 'Reeves': [671], 'LM,': [672, 1198], 'Lopresti-Morrow': [673], 'LL,': [674, 2603], 'Yocum': [675], 'SA,': [676, 1001], 'Rosner': [677], 'Cloning,': [681], 'expression,': [682], 'collagenolytic': [686, 2343], 'metalloproteinase-13': [690], '1996;': [698, 781, 1314, 1494, 1593, 1853, 2234, 2271, 2622, 2923, 2965, 2991, 3017, 3486], '97:': [699], '761–8.': [700], '17': [701], 'Shlopov': [702], 'BV,': [703], 'Lie': [704], 'W-R,': [705], 'Mainardi': [706], 'CL,': [707], 'Cole': [708], 'AA,': [709], 'Chubinskaya': [710], 'Hasty': [712], 'KA.': [713], 'Osteoarthritic': [714], 'lesions:': [715], 'involvement': [716], 'three': [718], 'different': [719, 2100], 'collagenases.': [720], '40:': [724, 1337, 2477, 3139, 3271], '2065–74.': [725], '18': [726], 'Imai': [727], 'Ohta': [729], 'Matsumoto': [731], 'Fujimoto': [733], 'Sato': [735], 'Seiki': [737], 'Expression': [741], 'membrane-type': [743], 'I': [744, 1392, 2835, 2911], 'activation': [748, 1962], 'progelatinase': [750], 'A': [751, 1183], 'Am': [756, 1696, 1850, 2692, 3224], 'Pathol': [758, 2694], '151:': [760, 2696], '245–56.': [761], '19': [762], 'Knauper': [763, 841], 'V,': [764, 842, 3028, 3379], 'Lopez-Otin': [765], 'Smith': [767], 'Knight': [769], 'G,': [770, 794, 840, 1530, 1568, 1600, 2176, 2599, 2635, 2860, 2928, 3381], 'Murphy': [771, 839], 'G.': [772], 'Biochemical': [773], 'characterization': [774, 902, 1010, 2651], 'collagenase-3.': [777], 'Biol': [779, 956, 1020, 1057, 1869, 1941, 1970, 2346, 2390, 3415], 'Chem': [780, 957, 1021, 1058, 1868, 1942, 1971, 2347], '271:': [782], '1544–50.': [783], '20': [784], 'Manner': [789], 'P,': [790, 2316, 2363, 2446, 2563, 2862, 2930, 3026, 3375, 3430], 'Nelson': [791, 1884], 'F,': [792, 999, 1570, 1979, 2174, 3101], 'Webb': [793, 1340], 'Selective': [799], 'enhancement': [800], 'collagenase-mediated': [802], 'resident': [805], 'cultured': [811], 'arrest': [815], 'synthetic': [818], 'spares': [821], 'collagenase': [822, 848, 2034, 2055, 2058], '(matrix': [824, 2036, 3111], '1).': [826], '2000;': [829, 1824, 2062, 2141, 3096, 3192], '43:': [830, 2063, 2142, 2800, 3402], '673–82.': [831], '21': [832], 'Last': [835], 'Neame': [837], 'Tschesche': [843, 877], 'Neutrophil': [847], '(MMP-8)': [849], 'cleaves': [850, 889], 'at': [851, 895, 940, 2099], 'site': [854, 943], 'E373-A374': [855], 'interglobular': [858, 909, 953], 'domain': [859, 910], 'aggrecan.': [862, 912, 3412], '1994;': [865, 2892, 3533], '304:': [866], '347–51.': [867], '22': [868], 'Buttner': [869], 'FH,': [870, 2673], 'Margerie': [873], 'Lichte': [875], 'Membrane': [883], '(MT1-MMP)': [888], 'recombinant': [891, 3205], 'substrate': [893], 'rAgg1mut': [894], 'MMP': [900], 'sites:': [901], 'MT1-MMP': [904], 'catabolic': [905, 1185, 2163], 'activities': [906], '1998;': [915, 1652, 1805, 1908, 1943, 1972, 2311, 2348, 2759, 3461, 3501], '333:': [916], '159–65.': [917], '23': [918], 'Gordy': [921], 'JT,': [922, 1172], 'Weidner': [923], 'JR,': [924, 1005], 'Ayala': [925], 'JH,': [928, 1462, 1509], 'HR,': [930], 'Cell-mediated': [933], '"aggrecanase"': [942], '(Glu373-Ala374)': [944], 'is': [945, 1207, 1225, 1427, 1959, 2154, 3114], 'primary': [947], 'event': [948], 'proteolysis': [950], 'domain.': [954], '270:': [959], '2550–6.': [960], '24': [961], 'Tortorella': [962], 'MD,': [963], 'Burn': [964], 'TC,': [965], 'Pratta': [966], 'MA,': [967], 'Abbaszade': [968, 994], 'Hollis': [970], 'JM,': [971, 2318], 'Liu': [972, 996], 'Purification': [976], 'cloning': [978], 'aggrecanase-1:': [980], 'member': [982], 'ADAMTS': [985, 1017], 'family': [986, 1043], 'proteins.': [988, 2889, 2962], 'Science': [989, 1166], '284:': [991], '1664–6.': [992], '25': [993], 'RQ,': [997], 'Yang': [998], 'Rosenfeld': [1000], 'Ross': [1002], 'OH,': [1003], 'Link': [1004], 'Cloning': [1008], 'ADAMTS11,': [1012], 'an': [1013, 1429, 2869, 3438], 'family.': [1018, 1055], '274:': [1023, 1060], '23443–50.': [1024], 'Hurskainen': [1026], 'TL,': [1027], 'Hirohata': [1028], 'Seldin': [1030], 'MF,': [1031], 'Apte': [1032], 'SS.': [1033], 'ADAM-TS5,': [1034], 'ADAM-TS6,': [1035], 'ADAM-TS7,': [1037], 'novel': [1038], 'members': [1039], 'new': [1042], 'zinc': [1045], 'metalloproteases:': [1046], 'general': [1047], 'features': [1048], 'genomic': [1050], 'distribution': [1051], 'ADAM-TS': [1054], '25555–63.': [1061], '27': [1062], 'Aigner': [1063, 1093, 1117], 'Gluckert': [1065], 'von': [1067], 'der': [1068, 3169, 3239], 'Mark': [1069], 'Activation': [1071], 'fibrillar': [1073], 'synthesis': [1075, 2375, 2956, 3254, 3265], 'phenotypic': [1077], 'modulation': [1078, 1098], 'chondrocytes': [1080, 1100, 1138, 1749, 1818, 1847, 1958, 2042, 2158, 2867, 2951, 3077], 'early': [1082], 'lesions.': [1086], '5:': [1090, 1361, 3160, 3417], '183–9.': [1091], '28': [1092], 'Dudhia': [1095], 'J.': [1096, 2182, 2407, 2864, 2938, 3109], 'Phenotypic': [1097, 3073], 'as': [1101, 1324, 1389], 'potential': [1103], 'therapeutic': [1104, 1434], 'target': [1105], 'osteoarthritis:': [1107, 1304, 1328, 1586, 3361], 'hypothesis.': [1109], '56:': [1114], '287–91.': [1115], '29': [1116], 'Zhu': [1119], 'Chansky': [1121], 'HH,': [1122], 'Matsen': [1123], 'FA': [1124], 'III,': [1125], 'Maloney': [1126], 'WJ,': [1127], 'Sandell': [1128], 'LJ.': [1129], 'Reexpression': [1130], 'IIA': [1133], 'procollagen': [1134], 'adult': [1136], '1443–50.': [1146], '30': [1147], 'Dayer': [1148, 1274, 2317], 'J-M,': [1149, 2180, 2357, 2405, 2936, 3107], 'Russell': [1150], 'RGG,': [1151], 'Krane': [1152], 'SM.': [1153], 'Collagenase': [1154], 'production': [1155, 1279, 1798, 1999, 2264, 2416, 2584], 'cells:': [1159], 'stimulation': [1160], 'lymphocyte': [1164], 'factor.': [1165], '1977;': [1167], '195:': [1168], '181–3.': [1169], '31': [1170], 'Dingle': [1171], 'Saklatvala': [1173, 1195], 'Tyler': [1177, 2828, 2898], 'Fell': [1179], 'HB,': [1180], 'Jubb': [1181], 'R.': [1182], 'factor': [1186, 1287, 1349, 1539, 1992, 2008, 2050, 2412, 2716, 2791, 2834, 2875, 2910, 2946, 2960, 2983, 3134, 3152], '1979;': [1191], '184:': [1192], '177–80.': [1193], '32': [1194], 'Pilsworth': [1197], 'Sarsfield': [1199, 2068], 'SJ,': [1200, 2069, 2119], 'Gavrilovic': [1201], 'Heath': [1203], 'JK.': [1204], 'Pig': [1205], 'catabolin': [1206], 'form': [1209], 'interleukin': [1211, 1547, 2711], '1:': [1212, 3298], 'resorb,': [1216], 'fibroblasts': [1217, 2502], 'make': [1218], 'prostaglandin': [1219, 1669, 2093, 2414], 'thymocyte': [1223], 'proliferation': [1224], 'augmented': [1226], 'response': [1228, 2553], 'one': [1230], 'protein.': [1231], '1984;': [1234], '224:': [1235], '461–6.': [1236], '33': [1237], 'MB.': [1239, 1319], 'Degradation': [1240], 'culture:': [1245], 'regulatory': [1246], 'factors.': [1247], 'H': [1252, 2094], 'r': [1253], 'DS': [1254], 'owell,': [1255], '281–345.': [1270], '34': [1271], 'Arend': [1272], 'WP,': [1273], 'J-M.': [1275], 'Inhibition': [1276, 2408], 'effects': [1281, 3034, 3081, 3262], 'interleukin-1': [1283, 1379, 1581, 1935], 'tumor': [1285, 1347, 1937, 2410], 'necrosis': [1286, 1348, 1538, 1938, 2411], 'α': [1288, 1540], '38:': [1295], '151–60.': [1296], '35': [1297], 'Westacott': [1298, 1342], 'CI,': [1299, 1343, 2026], 'Sharif': [1300], 'M.': [1301, 1682, 1792, 1814, 1952, 2152], 'Cytokines': [1302], 'mediators': [1305, 1326], 'or': [1306], 'markers': [1307, 3051], 'destruction?': [1310], '25:': [1315, 1698], '254–72.': [1316, 3557], '36': [1317], 'cytokines': [1323, 2420, 2770], 'inflammatory': [1325], 'lessons': [1329], 'animal': [1331, 2295, 2523], 'models.': [1332, 2524], 'Connect': [1333], 'Tissue': [1334], 'Res': [1335, 3016, 3060, 3095], '1–11.': [1338], '37': [1339], 'GR,': [1341], 'Elson': [1344], 'CJ.': [1345], 'Chondrocyte': [1346, 1793, 3148], 'receptors': [1350], 'focal': [1352], 'loss': [1353], '427–37.': [1362], '38': [1363], 'McCollum': [1366], 'DiBattista': [1368, 2857], 'Faure': [1370], 'M-P,': [1371], 'Chin': [1372], 'JA,': [1373, 1919, 1984, 2022, 2399, 2858, 3491], 'Fournier': [1374], 'receptor': [1380, 1393, 1582, 2332, 2372, 2947], 'normal': [1382, 2724], 'chondrocytes:': [1387, 2003, 2382], 'identification': [1388], 'analysis': [1395], 'binding': [1397, 2877, 2902, 2912, 2961], 'kinetics': [1398], 'biologic': [1400], 'function.': [1401], '35:': [1405, 2924], '530–40.': [1406], '39': [1407], 'Feldman': [1408], 'Bondeson': [1410], 'Brennan': [1412], 'FM,': [1413], 'Foxwell': [1414], 'BMJ,': [1415], 'Maini': [1416, 2636], 'RN.': [1417], 'rationale': [1419], 'current': [1422], 'boom': [1423], 'anti-TNFα': [1425, 1444], 'treatment:': [1426], 'there': [1428], 'effective': [1430], 'means': [1431], 'define': [1433], 'targets': [1435, 1862], 'drugs': [1437], 'provide': [1439], 'all': [1440], 'benefits': [1442], 'minimize': [1446], 'hazards?': [1447], '58:': [1452, 1558, 2785], '127–31.': [1453], '40': [1454], 'Evans': [1455, 1498, 1771, 2482], 'CH,': [1456, 1499, 2483], 'Robbins': [1457, 1769, 2490], 'PD,': [1458, 1770, 2491], 'Ghivizzani': [1459, 1500], 'SC,': [1460, 1501], 'Herndon': [1461, 1508], 'Kang': [1463, 1502], 'Bahnson': [1465], 'AB,': [1466], 'Clinical': [1469], 'trial': [1470], 'assess': [1472], 'safety,': [1474], 'feasibility,': [1475], 'efficacy': [1477], 'transferring': [1479], 'potentially': [1481], 'anti-arthritic': [1482], 'cytokine': [1483, 2216, 2263, 2497, 2654, 3149], 'gene': [1484, 1622, 1673, 1839, 1954, 2039, 2836, 3396], 'joints': [1487], 'Hum': [1491], 'Gene': [1492, 1512, 2494], 'Ther': [1493, 1852], '7:': [1495, 1678, 1780], '1261–80.': [1496], '41': [1497], 'Muzzonigro': [1504], 'Wasko': [1506], 'MC,': [1507, 3024, 3066, 3426], 'therapy': [1513], 'rheumatic': [1515], 'diseases.': [1516], '1–16.': [1521], '42': [1522], 'Van': [1523, 2514, 2665, 2699, 2763, 3163], 'den': [1524, 2515, 2677, 2706, 2764, 3173, 3243], 'Berg': [1525, 2516, 2678, 2707, 2765, 3174, 3244], 'WB,': [1526], 'Joosten': [1527, 2441], 'Kollias': [1529, 2634], 'van': [1531, 2671, 2676, 2705, 3168, 3172, 3231, 3238, 3242], 'de': [1532, 2666, 2700], 'Loo': [1533, 2667, 2701], 'FA.': [1534], 'Role': [1535, 2455, 2747], 'tumour': [1537], 'experimental': [1542, 1585, 2685], 'arthritis:': [1543, 2463, 2650, 2686], 'separate': [1544], '1β': [1548], 'chronicity': [1550], 'destruction.': [1553, 2473], '140–8.': [1559], '43': [1560], 'Caron': [1561], 'Fernandes': [1563], 'JC,': [1564, 2071], 'Tardif': [1567, 2175, 2859, 2927], 'Mineau': [1569, 1978], 'Geng': [1571, 2933], 'Chondroprotective': [1575], 'effect': [1576, 1612, 2465, 3130, 3203], 'intraarticular': [1578], 'injections': [1579], 'antagonist': [1583], 'suppression': [1587, 2736], 'collagenase-1': [1589], 'expression.': [1590, 1674], '39:': [1594, 2966, 2992], '1535–44.': [1595], '44': [1596], 'Jacques': [1597, 1734], 'Bereziat': [1599], 'Humbert': [1601, 1742], 'Corvol': [1603], 'Olivier': [1605], 'JL,': [1606], 'Masliah': [1607], 'Post-transcriptional': [1611], 'IGF-I': [1614], 'IL-1β-induced': [1616], 'secreted': [1619], 'phospholipase': [1620], 'A2': [1621], 'expression': [1623, 1667, 1840, 1955, 2040, 2335, 2837, 2940, 2954, 3046, 3153], 'rabbit': [1625], 'chondrocytes.': [1627, 1905, 2268], '1864–72.': [1633], '45': [1634], 'Clancy': [1635], 'Amin': [1637, 1701], 'AR,': [1638, 1702], 'Abramson': [1639], 'SB.': [1640, 2789], 'nitric': [1644, 1686, 1725, 1796, 1894, 1899, 1997, 2730], 'oxide': [1645, 1687, 1774, 1797, 1895, 1900, 1998, 2731], 'inflammation': [1647], 'immunity.': [1649], '41:': [1653, 1806, 2312, 3502], '1141–51.': [1654], '46': [1655], 'MB,': [1657, 1829], 'Berenbaum': [1658, 1744], 'F.': [1659, 1745, 3032], 'Human': [1660, 2865], 'culture': [1662, 1846, 3083], 'models': [1663, 3394], 'studying': [1665], 'cyclooxygenase': [1666], 'regulation': [1670, 2053, 2091], '386–8.': [1679], '47': [1680], 'Lotz': [1681, 1791, 1813, 1951, 2151], 'damage.': [1691], 'North': [1695], '269–82.': [1699], '48': [1700], 'Attur': [1703], 'Patel': [1705], 'RN,': [1706, 2637], 'Thakker': [1707], 'GD,': [1708], 'Marshall': [1709], 'Rediske': [1711], 'Superinduction': [1715], 'cyclooxygenase-2': [1717], 'osteoarthritis-affected': [1721], 'influence': [1723], 'oxide.': [1726], '1231–7.': [1732], '49': [1733], 'Sautet': [1736], 'Moldovan': [1738, 2173, 3100], 'Thomas': [1740], 'Cyclooxygenase': [1746], 'healthy': [1753], 'Rev': [1755], 'Rhum': [1756], 'Engl': [1757, 3530], 'Ed': [1758], '701–4.': [1761], '50': [1762], 'Studer': [1763], 'Jaffurs': [1765], 'Stefanovic-Racic': [1767], 'CH.': [1772], 'Nitric': [1773], '377–9.': [1781], '51': [1782], 'Hashimoto': [1783, 1811, 2147], 'Takahashi': [1785], 'Amiel': [1787], 'Coutts': [1789], 'RD,': [1790], 'apoptosis': [1794], 'during': [1799, 2684], 'experimentally': [1800], 'induced': [1801, 1933], '1266–74.': [1807], '52': [1808], 'Kuhn': [1809], 'IL-1β': [1815, 2587], 'protects': [1816], 'CD95-induced': [1820], 'apoptosis.': [1821], 'Immunol': [1823, 1907, 2103, 2166, 2660], '164:': [1825], '2233–9.': [1826], '53': [1827], 'Suen': [1830], 'L-F,': [1831], 'Yamin': [1832], 'Lai': [1834], 'W-FT.': [1835], 'Regulation': [1836], 'prostaglandins': [1842], 'interleukin-1β': [1844, 2196], 'fibroblasts.': [1849], '3:': [1854, 1871, 2559], '9–16.': [1855], '54': [1856], 'Lewis': [1857], 'Manning': [1859], 'AM.': [1860], 'anti-inflammatory': [1864], 'drugs.': [1865], 'Curr': [1866, 2525], 'Opin': [1867, 2526], '489–94.': [1872], '55': [1873], 'Badger': [1874, 2108], 'AM,': [1875, 2109], 'Cook': [1876], 'MN,': [1877], 'Newman-Tarr': [1880], 'TM,': [1881, 3356], 'Swift': [1882, 2116], 'BA,': [1883, 2117], 'AH,': [1885, 2244], 'SB203580': [1888], 'inhibits': [1889], 'p38': [1890, 2087, 2131], 'mitogen-activated': [1891, 1964, 2088, 2132], 'protein': [1892, 1965, 1988, 2010, 2012, 2089, 2133, 2913, 3087, 3248], 'kinase,': [1893, 2047, 2134], 'production,': [1896], 'inducible': [1898], 'synthase': [1901], 'bovine': [1903, 2816], 'cartilage-derived': [1904], '161:': [1909], '467–73.': [1910], '56': [1911], 'Ding': [1912], 'GJF,': [1913], 'Fischer': [1914], 'PA,': [1915, 2353], 'Boltz': [1916], 'Schmidt': [1918], 'Colaianne': [1920], 'Gough': [1922], 'Characterization': [1926], 'quantitation': [1928], 'NF-κB': [1930], 'nuclear': [1931, 1991, 2049], 'translocation': [1932], 'factor-α.': [1939], '273:': [1944, 1973, 2349], '28897–905.': [1945], '57': [1946], 'Shalom-Barak': [1947], 'Quach': [1949, 2149], 'Interleukin-17-induced': [1953], 'associated': [1960], 'kinases': [1966], 'NF-κB.': [1968], '27467–73.': [1974], '58': [1975], 'Jovanovic': [1980], 'Di': [1982, 2397], 'Battista': [1983, 2398], 'J-P.': [1986], 'Mitogen-activated': [1987], 'kinase': [1989, 2013], 'κB': [1993], 'together': [1994], 'regulate': [1995], 'interleukin-17–induced': [1996], 'possible': [2004, 2885, 3393], 'transactivating': [2007], 'mitogen–activated': [2009], 'kinase–activated': [2011], '(MAPKAPK).': [2014], '2399–409.': [2019], '59': [2020], 'Mengshol': [2021], 'Vincenti': [2023], 'MP,': [2024], 'Coon': [2025], 'Barchowsky': [2027], 'Brinckerhoff': [2029], 'CE.': [2030], 'Interleukin-1': [2031], 'induction': [2032, 2549], '13)': [2038, 3113], 'requires': [2043], 'p38,': [2044], 'c-Jun': [2045], 'N-terminal': [2046], 'κB:': [2051], 'differential': [2052], '3.': [2059], '801–11.': [2064], '60': [2065], 'Ridley': [2066], 'SH,': [2067], 'Lee': [2070], 'Bigg': [2072], 'HF,': [2073], 'Taylor': [2076], 'DJ,': [2077, 2605], 'Actions': [2080], 'IL-1': [2082], 'are': [2083, 2581, 2880], 'selectively': [2084], 'controlled': [2085], 'kinase:': [2090], 'synthase-2,': [2095], 'metalloproteinases,': [2096], 'IL-6': [2098, 2368, 2733], 'levels.': [2101], '158:': [2105], '3165–73.': [2106], '61': [2107], 'Griswold': [2110], 'DE,': [2111], 'Kapadia': [2112], 'Blake': [2114], 'Hoffman': [2118], 'Disease-modifying': [2122], 'SB': [2125], '242235,': [2126], 'selective': [2128], 'rat': [2136], 'adjuvant-induced': [2137], '175–83.': [2143], '62': [2144], 'Olee': [2145], 'IL-18': [2153], 'produced': [2155], 'induces': [2160], 'proinflammatory': [2161], 'responses.': [2164], '162:': [2168], '1096–100.': [2169], '63': [2170], 'Saha': [2171], 'J-P,': [2178, 2401, 2856, 2932, 3103], 'Cloutier': [2179, 2404, 2935, 3106], 'Interleukin-1β–converting': [2183], 'enzyme/caspase-1': [2184], 'tissues:': [2188], 'localization': [2189, 2304], 'maturation': [2194], 'interleukin-18.': [2198], '1577–87.': [2203], '64': [2204], 'Schlaak': [2205], 'JF,': [2206, 2827], 'Pfers': [2207], 'Meyer': [2209], 'Zum': [2210], 'Buschenfelde': [2211], 'KH,': [2212], 'Marker-Hermann': [2213], 'E.': [2214], 'Different': [2215, 3033], 'profiles': [2217], 'osteoarthritis,': [2225], 'arthritis': [2227, 2618], 'seronegative': [2229], 'spondylarthropathies.': [2230], 'Exp': [2232, 3058], 'Rheumatol': [2233, 2527, 2783, 2797, 2922, 3399], '14:': [2235, 3018], '155–62.': [2236], '65': [2237], 'Henrotin': [2238], 'YE,': [2239], 'De': [2240, 3371], 'Groote': [2241], 'Labasse': [2243], 'Gaspar': [2245], 'SE,': [2246], 'Zheng': [2247, 2532], 'SX,': [2248], 'Geenen': [2249], 'VG,': [2250], 'Effects': [2253, 2366], 'exogenous': [2255], 'IL-1β,': [2256], 'TNFα,': [2257], 'IL-6,': [2258], 'IL-8': [2259], 'LIF': [2261], '4:': [2272], '163–73.': [2273], '66': [2274], 'Curry': [2277], 'VA,': [2278], 'Summers': [2279], 'CA,': [2280, 2543], 'Riley': [2283], 'GP,': [2284], 'Life': [2285], 'PF,': [2286], 'oncostatin': [2292], 'M': [2293], 'connective': [2298], 'turnover': [2301], 'its': [2303, 2330, 2370, 2883], 'within': [2305], 'joint.': [2308, 2988], '1760–71.': [2313], '67': [2314], 'Silacci': [2315], 'Desgeorges': [2319, 2354], 'Peter': [2321, 2360], 'Manueddu': [2323], 'Guerne': [2325, 2352], 'PA.': [2326], 'Interleukin': [2327], '(IL)-6': [2328], 'soluble': [2331, 2371], 'induce': [2333], 'synoviocytes': [2337], 'chondrocytes,': [2339], 'block': [2341], 'IL-1-induced': [2342], 'activity.': [2344], '13625–9.': [2350], '68': [2351], 'Jaspar': [2356], 'Relic': [2358], 'Hoffmeyer': [2362], 'NO': [2377], 'release': [2378], 'comparison': [2383], 'IL-1.': [2385], 'Modulation': [2386], 'dexamethasone.': [2388], 'Matrix': [2389], '18:': [2392], '253–60.': [2393], '69': [2394], 'Alaaeddine': [2395], 'Kiansa': [2402], 'α–induced': [2413], 'E2': [2415], 'antiinflammatory': [2419], 'interleukin-4,': [2421], 'interleukin-10,': [2422], 'interleukin-13': [2424], 'fibroblasts:': [2428], 'distinct': [2429], 'targeting': [2430], 'signaling': [2433, 3319], 'pathways.': [2434, 3320], '710–8.': [2439], '70': [2440], 'LAB,': [2442], 'Lubberts': [2443], 'E,': [2444], 'Durez': [2445], 'Helsen': [2447], 'MMA,': [2448], 'Jacobs': [2449], 'MJM,': [2450], 'Goldman': [2451], 'interleukin-4': [2457, 2467], 'interleukin-10': [2459, 2469], 'murine': [2461, 3155, 3180], 'collagen-induced': [2462, 2617], 'protective': [2464], 'treatment': [2470], '249–60.': [2478], '71': [2479], 'Müller-Ladner': [2480], 'U,': [2481, 3022], 'Franklin': [2484, 2568], 'BN,': [2485], 'Roberts': [2486], 'CR,': [2487], 'Gay': [2488], 'RE,': [2489], 'transfer': [2495], 'into': [2499, 3314, 3340], 'SCID': [2505], 'mouse': [2506], 'model.': [2507], '490–7.': [2512], '72': [2513], 'WB.': [2517, 2679, 2708, 2766, 3175, 3245], 'Lessons': [2518], 'destruction': [2521, 2683, 2776], '9:': [2529, 2742], '221–8.': [2530], '73': [2531], 'Fletcher': [2534], 'Kozak': [2536], 'W,': [2537], 'Jiang': [2538], 'Hofmann': [2540], 'KJ,': [2541], 'Conn': [2542], 'Resistance': [2546], 'fever': [2548], 'impaired': [2551], 'acute-phase': [2552], 'interleukin-1β-deficient': [2555], 'mice.': [2556, 2620, 2691], 'Immunity': [2557], '9–19.': [2560], '74': [2561], 'Li': [2562], 'Allen': [2564], 'Banerjee': [2566], 'Herzog': [2570], 'Johnston': [2572], 'Mice': [2576], 'deficient': [2577], 'IL-1β-converting': [2579], 'enzyme': [2580, 2610], 'defective': [2582], 'mature': [2586], 'resistant': [2589], 'endotoxic': [2591], 'shock.': [2592], 'Cell': [2593, 3059, 3414], '80:': [2595], '401–11.': [2596], '75': [2597], 'Ku': [2598], 'Faust': [2600], 'Lauffer': [2602], 'Livingston': [2604], 'Harding': [2606], 'MW.': [2607], 'Interleukin-1β': [2608], 'converting': [2609], 'inhibition': [2611], 'blocks': [2612], 'progression': [2613], 'Cytokine': [2621, 2740], '8:': [2623, 3193], '377–86.': [2624], '76': [2625], 'Butler': [2626], 'DM,': [2627], 'Malfait': [2628], 'A-M,': [2629], 'Mason': [2630, 3146], 'LJ,': [2631], 'Warden': [2632], 'DBA/1mice': [2640], 'expressing': [2641], 'TNF-α': [2644], 'transgene': [2645], 'develop': [2646], 'severe,': [2648], 'erosive': [2649], 'cascade': [2655], 'cellular': [2657], 'composition.': [2658], '159:': [2662], '2867–76.': [2663], '77': [2664], 'FA,': [2668, 2702], 'Kuiper': [2669], 'Enckevort': [2672], 'Arntz': [2674, 2703], 'OJ,': [2675, 2704], 'Interleukin-6': [2680], 'reduces': [2681], 'study': [2688], 'interleukin-6-deficient': [2690, 2726], '177–91.': [2697], '78': [2698], 'Effect': [2709], 'leukaemia': [2714], 'inhibitory': [2715], 'metabolism': [2719], 'mice:': [2727], 'synthesis.': [2739], '453–62.': [2743], '79': [2744], 'Reddi': [2745], 'AH.': [2746], 'morphogenetic': [2749, 3004, 3037, 3086, 3208, 3247], 'proteins': [2750, 2814, 2903, 3038], 'skeletal': [2752, 3315, 3341], 'engineering': [2754], 'regeneration.': [2756, 3552], 'Nat': [2757], 'Biotech': [2758], '16:': [2760], '247–52.': [2761], '80': [2762], 'growth': [2772, 2812, 2833, 2874, 2909, 2945, 2959, 2982, 3133, 3151, 3187, 3288], 'factors': [2773, 3317], 'Z': [2782], '136–41.': [2786], '81': [2787], 'Trippel': [2788], 'Growth': [2790], 'actions': [2792], 'Suppl': [2798, 3400], '129–32.': [2801], '82': [2802], 'Morales': [2803], 'TI.': [2804], 'content': [2808], 'endogenous': [2810], 'insulin-like': [2811, 2832, 2873, 2908, 2944, 2958, 2981, 3287], 'factor-binding': [2813], 'Arch': [2819], 'Biophys': [2821], '343:': [2823], '164–72.': [2824], '83': [2825], 'Middleton': [2826], 'JA.': [2829, 2899], 'Upregulation': [2830], 'lesions': [2840], '51:': [2850], '440–7.': [2851], '84': [2852], 'Doré': [2853], 'Brazeau': [2861], 'possess': [2868], 'increased': [2870, 2953], 'number': [2871], 'sites': [2878], 'but': [2879, 3257], 'unresponsive': [2881], 'stimulation:': [2884], 'IGF-1–binding': [2888], '37:': [2893], '253–63.': [2894], '85': [2895], 'Chevalier': [2896], 'X,': [2897], 'Production': [2900], 'explants.': [2919], 'Br': [2920], '515–22.': [2925], '86': [2926], 'Reboul': [2929], 'Normal': [2939], '968–78.': [2967], '87': [2968], 'Fernihough': [2969], 'JK,': [2970], 'Billingham': [2971], 'MEJ,': [2972], 'Cwyfan-Hughes': [2973], 'Holly': [2975], 'JMP.': [2976], 'Local': [2977], 'disruption': [2978], 'system': [2984], 'arthritic': [2987, 3123], '1556–65.': [2993], '88': [2994], 'Sailor': [2995], 'LZ,': [2996], 'Hewick': [2997], 'Morris': [2999, 3200, 3236], 'EA.': [3000, 3201], 'Recombinant': [3001], 'protein-2': [3005, 3209], 'maintains': [3006], 'phenotype': [3010], 'long-term': [3012], 'culture.': [3013], 'Orthop': [3015, 3554], '937–45.': [3019], '89': [3020], 'Valcourt': [3021], 'Ronziere': [3023], 'Winkler': [3025], 'Rosen': [3027], 'Herbage': [3029], 'Mallein-Gerin': [3031], '2,': [3039, 3088], '4,': [3040], '12,': [3041], 'MC615': [3054], 'cell': [3056], 'line.': [3057], '251:': [3062], '264–74.': [3063], '90': [3064], 'Stewart': [3065], 'Saunders': [3067], 'KM,': [3068], 'Burton-Wurster': [3069], 'Macleod': [3071], 'JN.': [3072], 'stability': [3074], 'vitro:': [3079], 'models,': [3084], 'serum': [3090], 'supplementation.': [3091], 'Miner': [3094], '15:': [3097], '166–74.': [3098], '91': [3099], 'Hambor': [3104], 'Collagenase-3': [3110], 'metalloprotease': [3112], 'preferentially': [3115], 'localized': [3116], 'deep': [3119, 3519], 'layer': [3120], 'situ:': [3126], 'vitro': [3128], 'mimicking': [3129], 'transforming': [3132, 3186], 'β.': [3135], '1653–61.': [3140], '92': [3141], 'Chambers': [3142], 'MG,': [3143], 'Bayliss': [3144], 'MT,': [3145], 'RM.': [3147], '301–8.': [3161], '93': [3162], 'Beuningen': [3164, 3232], 'HM,': [3165, 3233], 'Glansbeek': [3166, 3229], 'HL,': [3167, 3230], 'Kraan': [3170, 3240], 'PM,': [3171, 3241], 'Osteoarthritis-like': [3176], 'changes': [3177], 'resulting': [3183], 'intra-articular': [3185], 'factor-β': [3188], 'injections.': [3189], '25–33.': [3194], '94': [3195], 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'II.': [3337], 'development-matrix': [3342], 'components': [3343], 'homeostasis.': [3346], '227–33.': [3351], '99': [3352], 'Holderbaum': [3353], 'Haqqi': [3355], 'Moskowitz': [3357], 'RW.': [3358], 'Genetics': [3359], 'exposing': [3362], 'iceberg.': [3364], '397–405.': [3369], '100': [3370], 'Crombrugghe': [3372], 'Katzenstein': [3374], 'Mukhopadhyay': [3376], 'Lefebvre': [3378], 'Zhou': [3380], 'Garofalo': [3382], 'Transgenic': [3386], 'mice': [3387, 3476], 'deficiencies': [3389], 'collagens:': [3392], 'therapy.': [3397], '140–2.': [3403], '101': [3404], 'Vertel': [3405], 'BM.': [3406], 'ins': [3408], 'outs': [3410], 'Trends': [3413], '458–64.': [3418], '102': [3419], 'Horton': [3420], 'WE': [3421], 'Jr,': [3422], 'Lethbridge-Cejku': [3423], 'Hochberg': [3425], 'Balakir': [3427], 'Precht': [3429], 'Plato': [3431], 'CC,': [3432], 'An': [3435], 'association': [3436], 'between': [3437], 'polymorphic': [3440], 'allele': [3441], 'bilateral': [3443], 'hand': [3444], 'elderly': [3447], 'white': [3448], 'men:': [3449], 'data': [3450], 'Baltimore': [3453], 'Longitudinal': [3454], 'Study': [3455], 'Aging': [3457], '(BLSA).': [3458], '245–51.': [3463], '103': [3464], 'Jacenko': [3465], 'Skeletal': [3471], 'hematopoietic': [3473], 'transgenic': [3477], 'X.': [3480], 'N': [3482, 3529], 'Y': [3483], 'Acad': [3484], 'Sci': [3485], '785:': [3487], '278–80.': [3488], '104': [3489], 'Buckwalter': [3490], 'Mankin': [3492], 'HJ.': [3493], 'Articular': [3494], 'repair': [3496, 3550], 'transplantation.': [3498, 3528], '1331–42.': [3503], '105': [3504], 'Brittberg': [3505], 'Lindahl': [3507], 'Nilsson': [3509], 'Ohlsson': [3511], 'Isaksson': [3513], 'Peterson': [3515], 'L.': [3516], 'autologous': [3526], 'Med': [3532], '331:': [3534], '889–95.': [3535], '106': [3536], 'Caplan': [3537], 'AI,': [3538], 'Elyaderani': [3539], 'Mochizuki': [3541], 'Wakitani': [3543], 'Goldberg': [3545], 'VM.': [3546], 'Principles': [3547], '342:': [3556], 'Citing': [3558], 'Literature': [3559], 'Volume43,': [3560], 'Issue9September': [3561], '2000Pages': [3562], 'ReferencesRelatedInformation': [3564]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2028149799', 'counts_by_year': [{'year': 2024, 'cited_by_count': 16}, {'year': 2023, 'cited_by_count': 20}, {'year': 2022, 'cited_by_count': 18}, {'year': 2021, 'cited_by_count': 35}, {'year': 2020, 'cited_by_count': 29}, {'year': 2019, 'cited_by_count': 34}, {'year': 2018, 'cited_by_count': 30}, {'year': 2017, 'cited_by_count': 27}, {'year': 2016, 'cited_by_count': 47}, {'year': 2015, 'cited_by_count': 32}, {'year': 2014, 'cited_by_count': 26}, {'year': 2013, 'cited_by_count': 32}, {'year': 2012, 'cited_by_count': 32}], 'updated_date': '2024-12-16T23:05:14.051353', 'created_date': '2016-06-24'}