Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2028149316', 'doi': 'https://doi.org/10.1089/rej.2008.0771', 'title': 'Long-Term Treatment with a Chinese Herbal Formula, Sheng-Mai-San, Improves Cardiac Contractile Function in Aged Rats: The Role of Ca<sup>2+</sup>Homeostasis', 'display_name': 'Long-Term Treatment with a Chinese Herbal Formula, Sheng-Mai-San, Improves Cardiac Contractile Function in Aged Rats: The Role of Ca<sup>2+</sup>Homeostasis', 'publication_year': 2008, 'publication_date': '2008-12-01', 'ids': {'openalex': 'https://openalex.org/W2028149316', 'doi': 'https://doi.org/10.1089/rej.2008.0771', 'mag': '2028149316', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19072253'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/rej.2008.0771', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171625771', 'display_name': 'Rejuvenation Research', 'issn_l': '1549-1684', 'issn': ['1549-1684', '1557-8577'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5009386607', 'display_name': 'Guangqin Zhang', 'orcid': 'https://orcid.org/0000-0002-0282-3807'}, 'institutions': [{'id': 'https://openalex.org/I161716053', 'display_name': 'China Pharmaceutical University', 'ror': 'https://ror.org/01sfm2718', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I161716053']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Guang-Qin Zhang', 'raw_affiliation_strings': ['Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.', 'institution_ids': ['https://openalex.org/I161716053']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100460842', 'display_name': 'Hui Wang', 'orcid': 'https://orcid.org/0000-0002-8549-3398'}, 'institutions': [{'id': 'https://openalex.org/I141568987', 'display_name': 'Hong Kong Baptist University', 'ror': 'https://ror.org/0145fw131', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I141568987']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Hui Wang', 'raw_affiliation_strings': ['School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.'], 'affiliations': [{'raw_affiliation_string': 'School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.', 'institution_ids': ['https://openalex.org/I141568987']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028770689', 'display_name': 'Wentao Liu', 'orcid': 'https://orcid.org/0000-0001-5534-7173'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wen-Tao Liu', 'raw_affiliation_strings': ['Department of Pharmacology, Nanjing Medical University, Nanjing, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, Nanjing Medical University, Nanjing, China.', 'institution_ids': ['https://openalex.org/I83519826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101638077', 'display_name': 'Hang Dong', 'orcid': 'https://orcid.org/0000-0003-4155-4547'}, 'institutions': [{'id': 'https://openalex.org/I141568987', 'display_name': 'Hong Kong Baptist University', 'ror': 'https://ror.org/0145fw131', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I141568987']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Hang Dong', 'raw_affiliation_strings': ['School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.'], 'affiliations': [{'raw_affiliation_string': 'School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.', 'institution_ids': ['https://openalex.org/I141568987']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017660514', 'display_name': 'Wang-Fun Fong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141568987', 'display_name': 'Hong Kong Baptist University', 'ror': 'https://ror.org/0145fw131', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I141568987']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Wang-Fun Fong', 'raw_affiliation_strings': ['School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.'], 'affiliations': [{'raw_affiliation_string': 'School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.', 'institution_ids': ['https://openalex.org/I141568987']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101541446', 'display_name': 'Limin Tang', 'orcid': 'https://orcid.org/0000-0002-4078-8934'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li-Min Tang', 'raw_affiliation_strings': ['Laboratory for Quality Control, Jiangxi Jurentang Pharmaceutical Co. Ltd., Nanchang, China.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Quality Control, Jiangxi Jurentang Pharmaceutical Co. Ltd., Nanchang, China.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086551354', 'display_name': 'Yun-Hua Xiong', 'orcid': None}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yun-Hua Xiong', 'raw_affiliation_strings': ['Laboratory for Quality Control, Jiangxi Jurentang Pharmaceutical Co. Ltd., Nanchang, China.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Quality Control, Jiangxi Jurentang Pharmaceutical Co. Ltd., Nanchang, China.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013824415', 'display_name': 'Zhi‐Ling Yu', 'orcid': 'https://orcid.org/0000-0002-2979-9608'}, 'institutions': [{'id': 'https://openalex.org/I141568987', 'display_name': 'Hong Kong Baptist University', 'ror': 'https://ror.org/0145fw131', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I141568987']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Zhi-Ling Yu', 'raw_affiliation_strings': ['School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.'], 'affiliations': [{'raw_affiliation_string': 'School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.', 'institution_ids': ['https://openalex.org/I141568987']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103705689', 'display_name': 'Kam‐Ming Ko', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I889458895', 'display_name': 'University of Hong Kong', 'ror': 'https://ror.org/02zhqgq86', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I889458895']}, {'id': 'https://openalex.org/I200769079', 'display_name': 'Hong Kong University of Science and Technology', 'ror': 'https://ror.org/00q4vv597', 'country_code': 'HK', 'type': 'education', 'lineage': ['https://openalex.org/I200769079']}], 'countries': ['HK'], 'is_corresponding': False, 'raw_author_name': 'Kam-Ming Ko', 'raw_affiliation_strings': ['Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.', 'institution_ids': ['https://openalex.org/I889458895', 'https://openalex.org/I200769079']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.622, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 17, 'citation_normalized_percentile': {'value': 0.798565, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '11', 'issue': '6', 'first_page': '0991', 'last_page': '1000'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11057', 'display_name': 'Cardiac Ischemia and Reperfusion', 'score': 0.9811, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9779, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/homeostasis', 'display_name': 'Homeostasis', 'score': 0.6589087}], 'concepts': [{'id': 'https://openalex.org/C63645605', 'wikidata': 'https://www.wikidata.org/wiki/Q103191', 'display_name': 'Homeostasis', 'level': 2, 'score': 0.6589087}, {'id': 'https://openalex.org/C61797465', 'wikidata': 'https://www.wikidata.org/wiki/Q1188986', 'display_name': 'Term (time)', 'level': 2, 'score': 0.5609433}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.54182154}, {'id': 'https://openalex.org/C111566952', 'wikidata': 'https://www.wikidata.org/wiki/Q1303462', 'display_name': 'Cardiac function curve', 'level': 3, 'score': 0.5021117}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.42108983}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.41663647}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.39405635}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.32003158}, {'id': 'https://openalex.org/C2778198053', 'wikidata': 'https://www.wikidata.org/wiki/Q181754', 'display_name': 'Heart failure', 'level': 2, 'score': 0.24122015}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.09570697}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004365', 'descriptor_name': 'Drugs, Chinese Herbal', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D009200', 'descriptor_name': 'Myocardial Contraction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004338', 'descriptor_name': 'Drug Combinations', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004365', 'descriptor_name': 'Drugs, Chinese Herbal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018613', 'descriptor_name': 'Microscopy, Confocal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009200', 'descriptor_name': 'Myocardial Contraction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019837', 'descriptor_name': 'Ryanodine Receptor Calcium Release Channel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019837', 'descriptor_name': 'Ryanodine Receptor Calcium Release Channel', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D053498', 'descriptor_name': 'Sarcoplasmic Reticulum Calcium-Transporting ATPases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053498', 'descriptor_name': 'Sarcoplasmic Reticulum Calcium-Transporting ATPases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/rej.2008.0771', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171625771', 'display_name': 'Rejuvenation Research', 'issn_l': '1549-1684', 'issn': ['1549-1684', '1557-8577'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19072253', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.71, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W10855421', 'https://openalex.org/W1517993017', 'https://openalex.org/W1525577992', 'https://openalex.org/W1775749144', 'https://openalex.org/W1951805102', 'https://openalex.org/W1972878150', 'https://openalex.org/W1974306732', 'https://openalex.org/W1990563309', 'https://openalex.org/W2002922269', 'https://openalex.org/W2005586571', 'https://openalex.org/W2010356271', 'https://openalex.org/W2011038097', 'https://openalex.org/W2013764640', 'https://openalex.org/W2016916149', 'https://openalex.org/W2037637716', 'https://openalex.org/W2053917755', 'https://openalex.org/W2054225000', 'https://openalex.org/W2069230499', 'https://openalex.org/W2078608151', 'https://openalex.org/W2079286233', 'https://openalex.org/W2089676520', 'https://openalex.org/W2090619430', 'https://openalex.org/W2093542277', 'https://openalex.org/W2122031584', 'https://openalex.org/W2122671565', 'https://openalex.org/W2149665116', 'https://openalex.org/W2151339600', 'https://openalex.org/W2167438164', 'https://openalex.org/W2170853624', 'https://openalex.org/W2266572207', 'https://openalex.org/W2344164893', 'https://openalex.org/W2354394400', 'https://openalex.org/W2384062717', 'https://openalex.org/W2394708990', 'https://openalex.org/W2977097895', 'https://openalex.org/W324460766'], 'related_works': ['https://openalex.org/W4313265328', 'https://openalex.org/W42295635', 'https://openalex.org/W3197510923', 'https://openalex.org/W3096145648', 'https://openalex.org/W2497592525', 'https://openalex.org/W2370579019', 'https://openalex.org/W2365267743', 'https://openalex.org/W2330575325', 'https://openalex.org/W2163803519', 'https://openalex.org/W1973996291'], 'abstract_inverted_index': {'A': [0], 'Chinese': [1], 'herbal': [2], 'formula': [3], 'Sheng-Mai-Yin': [4], '(SMY),': [5], 'the': [6, 26, 32, 48, 52, 59, 145, 149, 159, 182, 196, 211, 217, 224, 247], 'liquid': [7], 'dosage': [8], 'form': [9], 'of': [10, 28, 35, 54, 61, 80, 97, 151, 172, 198, 203, 213, 219], 'Sheng-Mai-San,': [11], 'has': [12], 'been': [13], 'used': [14], 'clinically': [15], 'for': [16, 127], 'treating': [17], 'heart': [18], 'failure,': [19], 'particularly': [20], 'in': [21, 43, 51, 67, 82, 138, 154, 162, 165, 169, 175, 210, 226, 234, 243], 'aged': [22, 36, 44, 72, 139, 155, 235], 'patients.': [23], 'To': [24, 46], 'investigate': [25], 'effect': [27, 60], 'SMY': [29, 62, 121, 141, 179, 232], 'treatment': [30, 63, 122, 142, 180, 233], 'on': [31, 64], 'contractile': [33, 228], 'function': [34, 229], 'hearts,': [37], 'we': [38, 57], 'first': [39], 'examined': [40], 'cardiac': [41, 55, 83, 227], 'hemodynamics': [42], 'rats.': [45, 73, 140], 'define': [47], 'mechanism': [49], 'involved': [50], 'enhancement': [53], 'function,': [56], 'investigated': [58], 'Ca2+': [65, 74, 84, 87, 102, 152, 173, 184, 188, 214, 220, 244, 251], 'homeostasis': [66], 'ventricular': [68], 'cardiomyocytes': [69], 'isolated': [70], 'from': [71, 246], 'release': [75, 245], 'was': [76, 114], 'assessed': [77], 'by': [78, 231, 240], 'measurements': [79], 'changes': [81, 168], 'transients': [85, 153, 215], 'and': [86, 110, 147, 157, 167, 190, 194, 216], 'sparks,': [88], 'using': [89], 'laser': [90], 'scanning': [91], 'confocal': [92], 'microscopy.': [93], 'The': [94, 117], 'functional': [95], 'status': [96], 'Ca2+-release': [98], 'regulators,': [99], 'including': [100], 'L-type': [101, 183, 250], 'channels,': [103], 'sarcoplasmic': [104], 'reticulum': [105], '(SR)': [106], 'Ca2+-adenosine': [107], 'triphosphatase': [108], '(ATPase),': [109], 'ryanodine': [111], 'receptors': [112], '(RyRs),': [113], 'also': [115], 'assessed.': [116], 'results': [118], 'indicated': [119], 'that': [120], '(2': [123], 'g/kg': [124], 'per': [125], 'day': [126], '30': [128], 'doses': [129], 'within': [130], '6': [131], 'weeks,': [132], 'intragastically)': [133], 'significantly': [134], 'improved': [135], 'hemodynamic': [136], 'parameters': [137], 'markedly': [143], 'increased': [144, 181], 'amplitude': [146, 212], 'shortened': [148], 'duration': [150], 'cardiomyocytes,': [156], 'reversed': [158], 'age-related': [160], 'increase': [161, 242], 'frequency,': [163], 'decrease': [164], 'amplitude,': [166], 'spatiotemporal': [170], 'properties': [171], 'sparks': [174], 'cardiomyocytes.': [176], 'In': [177, 222], 'addition,': [178], 'current': [185], 'density,': [186], 'SR': [187, 191, 248], 'content,': [189], 'Ca2+-ATPase': [192], 'expression,': [193], 'decreased': [195], 'sensitivity': [197], 'RyRs': [199], 'to': [200, 208], 'Ca2+,': [201], 'all': [202], 'which': [204], 'are': [205], 'causally': [206], 'related': [207], 'increases': [209], 'size': [218], 'sparks.': [221], 'conclusion,': [223], 'improvement': [225], 'afforded': [230], 'rats': [236], 'is': [237], 'likely': [238], 'mediated': [239], 'an': [241], 'through': [249], 'current-activated': [252], 'RyRs.': [253]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2028149316', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}], 'updated_date': '2024-12-09T22:00:01.220548', 'created_date': '2016-06-24'}