Title: Cerebral infarction in a patient with acute lymphoblastic leukemia after fresh‐frozen plasma replacement during l‐asparaginase therapy
Abstract: American Journal of HematologyVolume 41, Issue 4 p. 295-296 Letters and CorrespondenceFree Access Cerebral infarction in a patient with acute lymphoblastic leukemia after fresh-frozen plasma replacement during l-asparaginase therapy Hideshi Ishii, Hideshi Ishii Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorHakumei Oh, Hakumei Oh Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorNobuko Ishizuka, Nobuko Ishizuka Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorYasuhiro Matsuura, Yasuhiro Matsuura Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorHirotoshi Nakamura, Hirotoshi Nakamura Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorTakayoshi Asai, Takayoshi Asai Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorSho Yoshida, Sho Yoshida Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this author Hideshi Ishii, Hideshi Ishii Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorHakumei Oh, Hakumei Oh Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorNobuko Ishizuka, Nobuko Ishizuka Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorYasuhiro Matsuura, Yasuhiro Matsuura Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorHirotoshi Nakamura, Hirotoshi Nakamura Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorTakayoshi Asai, Takayoshi Asai Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this authorSho Yoshida, Sho Yoshida Second Department of Internal Medicine, Chiba University School of Medicine, Inohana, Chiba-City, JapanSearch for more papers by this author First published: December 1992 https://doi.org/10.1002/ajh.2830410415Citations: 6AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1 Clavell LA, Gelber RD, Cohen HJ, Hitchcock-Bryan S, Cassady JR, Tarbell NJ, Blattner SR, Tantravahi R, Leavitt P, Sallan SE: Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia. N Engl J Med 315: 657, 1986. 2 Cairo MS, Lazarus K, Gilmore RL, Baehner RL: Intracranial hemorrhage and focal seizures secondary to use of L-asparaginase during induction therapy of acute lymphocytic leukemia. J Pediatr 97: 829, 1980. 3 Priest JR, Ramsay NKC, Latchaw RE, Lockman LA, Hasegawa DK, Coates TD, Coccia PF, Edson JR, Nesbit ME, Krivit W: Thrombotic and hemorrhagic strokes complicating early therapy for childhood acute lymphoblastic leukemia. Cancer 46: 1548, 1980. 4 Urban C, Sager W-D: Intracranial bleeding during therapy with L-asparaginase in childhood acute lymphocytic leukemia. Eur J Pediatr 137: 323, 1981. 5 Conard J, Cazenave B, Maury J, Horellou MH, Samama M: L-asparaginase, antithrombin III, and thrombosis. Lancet 1: 1091, 1980. 6 Kucuk O, Kwaan HC, Gunnar W, Vazquez RM: Thromboembolic complications associated with L-asparaginase therapy. Etiologic role of low antithrombin III and plasminogen levels and therapeutic correction by fresh frozen plasma. Cancer 55: 702, 1985. 7 Conard J, Horellou MH, Dreden PV, Potevin F, Zittoun R, Samama M: Decrease in protein C in L-asparaginase-treated patients. Br J Haematol 59: 725, 1985. 8 Priest JR, Ramsay NKC, Steinherz PG, Tubergen DG, Cairo MS, Sitarz AL, Bishop AJ, White L, Trigg ME, Levitt CJ, Cich JA, Coccia PF: A syndrome of thrombosis and hemorrhage complicating L-asparasinase therapy for childhood acute lymphoblastic leukemia. J Pediatr 100: 984, 1982. 9 Muntean W: Hemorrhagic complications of L-asparaginase therapy. J Pediatr 102: 483, 1983. Citing Literature Volume41, Issue4December 1992Pages 295-296 ReferencesRelatedInformation