Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2027406087', 'doi': 'https://doi.org/10.1016/j.brainresbull.2008.09.005', 'title': 'Descending pathways from activated locus coeruleus/subcoeruleus following unilateral hindpaw inflammation in the rat', 'display_name': 'Descending pathways from activated locus coeruleus/subcoeruleus following unilateral hindpaw inflammation in the rat', 'publication_year': 2008, 'publication_date': '2008-10-15', 'ids': {'openalex': 'https://openalex.org/W2027406087', 'doi': 'https://doi.org/10.1016/j.brainresbull.2008.09.005', 'mag': '2027406087', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18926888'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.brainresbull.2008.09.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8119441', 'display_name': 'Brain Research Bulletin', 'issn_l': '0361-9230', 'issn': ['0361-9230', '1873-2747'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5112088244', 'display_name': 'Masako Maeda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I119182057', 'display_name': 'Showa University', 'ror': 'https://ror.org/04mzk4q39', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119182057']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masako Maeda', 'raw_affiliation_strings': ['Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.', 'institution_ids': ['https://openalex.org/I119182057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019582331', 'display_name': 'Masayoshi Tsuruoka', 'orcid': 'https://orcid.org/0000-0001-6891-689X'}, 'institutions': [{'id': 'https://openalex.org/I119182057', 'display_name': 'Showa University', 'ror': 'https://ror.org/04mzk4q39', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119182057']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masayoshi Tsuruoka', 'raw_affiliation_strings': ['Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.', 'institution_ids': ['https://openalex.org/I119182057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049536188', 'display_name': 'Bunsho Hayashi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I119182057', 'display_name': 'Showa University', 'ror': 'https://ror.org/04mzk4q39', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119182057']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Bunsho Hayashi', 'raw_affiliation_strings': ['Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.', 'institution_ids': ['https://openalex.org/I119182057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056213116', 'display_name': 'Ikuko Nagasawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I119182057', 'display_name': 'Showa University', 'ror': 'https://ror.org/04mzk4q39', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119182057']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ikuko Nagasawa', 'raw_affiliation_strings': ['Department of Anesthesiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Anesthesiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan', 'institution_ids': ['https://openalex.org/I119182057']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5083301071', 'display_name': 'Tomio Inoue', 'orcid': 'https://orcid.org/0000-0001-6848-0491'}, 'institutions': [{'id': 'https://openalex.org/I119182057', 'display_name': 'Showa University', 'ror': 'https://ror.org/04mzk4q39', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I119182057']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomio Inoue', 'raw_affiliation_strings': ['Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Oral Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.', 'institution_ids': ['https://openalex.org/I119182057']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2700, 'currency': 'USD', 'value_usd': 2700, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.385, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 21, 'citation_normalized_percentile': {'value': 0.760094, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '78', 'issue': '4-5', 'first_page': '170', 'last_page': '174'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10196', 'display_name': 'Pain Mechanisms and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10196', 'display_name': 'Pain Mechanisms and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/locus-coeruleus', 'display_name': 'Locus coeruleus', 'score': 0.837193}], 'concepts': [{'id': 'https://openalex.org/C2778468602', 'wikidata': 'https://www.wikidata.org/wiki/Q1470452', 'display_name': 'Locus coeruleus', 'level': 3, 'score': 0.837193}, {'id': 'https://openalex.org/C2779245659', 'wikidata': 'https://www.wikidata.org/wiki/Q1633866', 'display_name': 'Hyperalgesia', 'level': 4, 'score': 0.64459634}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.6143576}, {'id': 'https://openalex.org/C15490471', 'wikidata': 'https://www.wikidata.org/wiki/Q2734305', 'display_name': 'Nociception', 'level': 3, 'score': 0.49952698}, {'id': 'https://openalex.org/C2780775167', 'wikidata': 'https://www.wikidata.org/wiki/Q9606', 'display_name': 'Spinal cord', 'level': 2, 'score': 0.49714497}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.48706535}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.4823415}, {'id': 'https://openalex.org/C46762472', 'wikidata': 'https://www.wikidata.org/wiki/Q178648', 'display_name': 'Peripheral', 'level': 2, 'score': 0.4249367}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.41803044}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.41644293}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.40641305}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.33259487}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.096485674}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007839', 'descriptor_name': 'Functional Laterality', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D006614', 'descriptor_name': 'Hindlimb', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D008125', 'descriptor_name': 'Locus Coeruleus', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D009434', 'descriptor_name': 'Neural Pathways', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002351', 'descriptor_name': 'Carrageenan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002351', 'descriptor_name': 'Carrageenan', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D002351', 'descriptor_name': 'Carrageenan', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007839', 'descriptor_name': 'Functional Laterality', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006614', 'descriptor_name': 'Hindlimb', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006930', 'descriptor_name': 'Hyperalgesia', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D006930', 'descriptor_name': 'Hyperalgesia', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D006930', 'descriptor_name': 'Hyperalgesia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007279', 'descriptor_name': 'Injections, Subcutaneous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008125', 'descriptor_name': 'Locus Coeruleus', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008125', 'descriptor_name': 'Locus Coeruleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009434', 'descriptor_name': 'Neural Pathways', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D009434', 'descriptor_name': 'Neural Pathways', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016627', 'descriptor_name': 'Oxidopamine', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D016627', 'descriptor_name': 'Oxidopamine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D016627', 'descriptor_name': 'Oxidopamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010146', 'descriptor_name': 'Pain', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D010147', 'descriptor_name': 'Pain Measurement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010147', 'descriptor_name': 'Pain Measurement', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011930', 'descriptor_name': 'Reaction Time', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011930', 'descriptor_name': 'Reaction Time', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011930', 'descriptor_name': 'Reaction Time', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D013565', 'descriptor_name': 'Sympatholytics', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D013565', 'descriptor_name': 'Sympatholytics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013565', 'descriptor_name': 'Sympatholytics', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.brainresbull.2008.09.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8119441', 'display_name': 'Brain Research Bulletin', 'issn_l': '0361-9230', 'issn': ['0361-9230', '1873-2747'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18926888', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.66}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W140592118', 'https://openalex.org/W1965584870', 'https://openalex.org/W1986694311', 'https://openalex.org/W1988582096', 'https://openalex.org/W1997114005', 'https://openalex.org/W2002377251', 'https://openalex.org/W2014007136', 'https://openalex.org/W2022012727', 'https://openalex.org/W2025797318', 'https://openalex.org/W2031741199', 'https://openalex.org/W2033667415', 'https://openalex.org/W2035995551', 'https://openalex.org/W2037053212', 'https://openalex.org/W2045323923', 'https://openalex.org/W2049703682', 'https://openalex.org/W2050608362', 'https://openalex.org/W2062974262', 'https://openalex.org/W2072089656', 'https://openalex.org/W2072344109', 'https://openalex.org/W2080745413', 'https://openalex.org/W2087454739', 'https://openalex.org/W2096428903', 'https://openalex.org/W2105144695', 'https://openalex.org/W2107150131', 'https://openalex.org/W2161934021', 'https://openalex.org/W2163815564', 'https://openalex.org/W2201897764', 'https://openalex.org/W2287996637', 'https://openalex.org/W2468424440', 'https://openalex.org/W249845531', 'https://openalex.org/W4300168251'], 'related_works': ['https://openalex.org/W2350159966', 'https://openalex.org/W2049912867', 'https://openalex.org/W2041917376', 'https://openalex.org/W2025379423', 'https://openalex.org/W2014007136', 'https://openalex.org/W2012561402', 'https://openalex.org/W1994559013', 'https://openalex.org/W1989487268', 'https://openalex.org/W1976105490', 'https://openalex.org/W1973434522'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2027406087', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-16T05:43:39.432186', 'created_date': '2016-06-24'}