Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2027368040', 'doi': 'https://doi.org/10.1186/1471-2164-13-685', 'title': 'Stage-specific expression of protease genes in the apicomplexan parasite, Eimeria tenella', 'display_name': 'Stage-specific expression of protease genes in the apicomplexan parasite, Eimeria tenella', 'publication_year': 2012, 'publication_date': '2012-12-01', 'ids': {'openalex': 'https://openalex.org/W2027368040', 'doi': 'https://doi.org/10.1186/1471-2164-13-685', 'mag': '2027368040', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23216867', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3770453'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1471-2164-13-685', 'pdf_url': 'https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/1471-2164-13-685', 'source': {'id': 'https://openalex.org/S28614077', 'display_name': 'BMC Genomics', 'issn_l': '1471-2164', 'issn': ['1471-2164'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/1471-2164-13-685', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5013524246', 'display_name': 'Marilyn Katrib', 'orcid': 'https://orcid.org/0000-0002-1572-8147'}, 'institutions': [{'id': 'https://openalex.org/I114017466', 'display_name': 'University of Technology Sydney', 'ror': 'https://ror.org/03f0f6041', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I114017466']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Marilyn Katrib', 'raw_affiliation_strings': ['Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia'], 'affiliations': [{'raw_affiliation_string': 'Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia', 'institution_ids': ['https://openalex.org/I114017466']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009466626', 'display_name': 'Rowan J. Ikin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114017466', 'display_name': 'University of Technology Sydney', 'ror': 'https://ror.org/03f0f6041', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I114017466']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Rowan J Ikin', 'raw_affiliation_strings': ['Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia'], 'affiliations': [{'raw_affiliation_string': 'Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia', 'institution_ids': ['https://openalex.org/I114017466']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049927151', 'display_name': 'Fabien Brossier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1314251682', 'display_name': 'Institut National de la Recherche Agronomique', 'ror': 'https://ror.org/05y503v71', 'country_code': 'MA', 'type': 'facility', 'lineage': ['https://openalex.org/I1314251682']}], 'countries': ['MA'], 'is_corresponding': False, 'raw_author_name': 'Fabien Brossier', 'raw_affiliation_strings': ['INRA UR1282, Equipe Pathogenèse des Coccidioses, Infectiologie Animale et Santé Publique, Nouzilly, France'], 'affiliations': [{'raw_affiliation_string': 'INRA UR1282, Equipe Pathogenèse des Coccidioses, Infectiologie Animale et Santé Publique, Nouzilly, France', 'institution_ids': ['https://openalex.org/I1314251682']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103557509', 'display_name': 'Michelle Robinson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114017466', 'display_name': 'University of Technology Sydney', 'ror': 'https://ror.org/03f0f6041', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I114017466']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Michelle Robinson', 'raw_affiliation_strings': ['Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia'], 'affiliations': [{'raw_affiliation_string': 'Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia', 'institution_ids': ['https://openalex.org/I114017466']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073025962', 'display_name': 'Iveta Šlapetová', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114017466', 'display_name': 'University of Technology Sydney', 'ror': 'https://ror.org/03f0f6041', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I114017466']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Iveta Slapetova', 'raw_affiliation_strings': ['Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia'], 'affiliations': [{'raw_affiliation_string': 'Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia', 'institution_ids': ['https://openalex.org/I114017466']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037671272', 'display_name': 'Philippa A Sharman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I86467917', 'display_name': 'James Cook University', 'ror': 'https://ror.org/04gsp2c11', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I86467917']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Philippa A Sharman', 'raw_affiliation_strings': ['Queensland Tropical Health Alliance Research Laboratory, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Smithfield, Australia'], 'affiliations': [{'raw_affiliation_string': 'Queensland Tropical Health Alliance Research Laboratory, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Smithfield, Australia', 'institution_ids': ['https://openalex.org/I86467917']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042025873', 'display_name': 'Robert Walker', 'orcid': 'https://orcid.org/0000-0003-0032-9925'}, 'institutions': [{'id': 'https://openalex.org/I86467917', 'display_name': 'James Cook University', 'ror': 'https://ror.org/04gsp2c11', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I86467917']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Robert A Walker', 'raw_affiliation_strings': ['Queensland Tropical Health Alliance Research Laboratory, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Smithfield, Australia'], 'affiliations': [{'raw_affiliation_string': 'Queensland Tropical Health Alliance Research Laboratory, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Smithfield, Australia', 'institution_ids': ['https://openalex.org/I86467917']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032951606', 'display_name': 'Sabina I. Belli', 'orcid': 'https://orcid.org/0000-0003-3845-326X'}, 'institutions': [{'id': 'https://openalex.org/I114017466', 'display_name': 'University of Technology Sydney', 'ror': 'https://ror.org/03f0f6041', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I114017466']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Sabina I Belli', 'raw_affiliation_strings': ['Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia'], 'affiliations': [{'raw_affiliation_string': 'Institute for the Biotechnology of Infectious Diseases, University of Technology, 2007, Sydney, Broadway, Australia', 'institution_ids': ['https://openalex.org/I114017466']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044494740', 'display_name': 'Fiona M. Tomley', 'orcid': 'https://orcid.org/0000-0003-2188-8013'}, 'institutions': [{'id': 'https://openalex.org/I133836048', 'display_name': 'Royal Veterinary College', 'ror': 'https://ror.org/01wka8n18', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I133836048']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Fiona M Tomley', 'raw_affiliation_strings': ['Royal Veterinary College, Hatfield, UK'], 'affiliations': [{'raw_affiliation_string': 'Royal Veterinary College, Hatfield, UK', 'institution_ids': ['https://openalex.org/I133836048']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5078417632', 'display_name': 'Nicholas C. Smith', 'orcid': 'https://orcid.org/0000-0002-7467-1451'}, 'institutions': [{'id': 'https://openalex.org/I86467917', 'display_name': 'James Cook University', 'ror': 'https://ror.org/04gsp2c11', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I86467917']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Nicholas C Smith', 'raw_affiliation_strings': ['Queensland Tropical Health Alliance Research Laboratory, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Smithfield, Australia'], 'affiliations': [{'raw_affiliation_string': 'Queensland Tropical Health Alliance Research Laboratory, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Smithfield, Australia', 'institution_ids': ['https://openalex.org/I86467917']}]}], 'countries_distinct_count': 3, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1570, 'currency': 'GBP', 'value_usd': 1925, 'provenance': 'doaj'}, 'apc_paid': {'value': 1570, 'currency': 'GBP', 'value_usd': 1925, 'provenance': 'doaj'}, 'fwci': 3.356, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 33, 'citation_normalized_percentile': {'value': 0.917057, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '13', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12691', 'display_name': 'Poultry Coccidiosis Research and Control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1103', 'display_name': 'Animal Science and Zoology'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12691', 'display_name': 'Poultry Coccidiosis Research and Control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1103', 'display_name': 'Animal Science and Zoology'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11086', 'display_name': 'Epidemiology and Molecular Characterization of Parasitic Diseases', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria', 'score': 0.987, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/rhomboid', 'display_name': 'Rhomboid', 'score': 0.43806458}, {'id': 'https://openalex.org/keywords/eimeria-species', 'display_name': 'Eimeria Species', 'score': 0.428995}], 'concepts': [{'id': 'https://openalex.org/C182220744', 'wikidata': 'https://www.wikidata.org/wiki/Q7251226', 'display_name': 'Proteases', 'level': 3, 'score': 0.92182076}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8648291}, {'id': 'https://openalex.org/C2777976947', 'wikidata': 'https://www.wikidata.org/wiki/Q795375', 'display_name': 'Eimeria', 'level': 2, 'score': 0.7142584}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.62998354}, {'id': 'https://openalex.org/C2776714187', 'wikidata': 'https://www.wikidata.org/wiki/Q212410', 'display_name': 'Protease', 'level': 3, 'score': 0.5827663}, {'id': 'https://openalex.org/C2781023229', 'wikidata': 'https://www.wikidata.org/wiki/Q193030', 'display_name': 'Apicomplexa', 'level': 4, 'score': 0.51693195}, {'id': 'https://openalex.org/C99389464', 'wikidata': 'https://www.wikidata.org/wiki/Q3319949', 'display_name': 'Gametocyte', 'level': 4, 'score': 0.46087366}, {'id': 'https://openalex.org/C50729890', 'wikidata': 'https://www.wikidata.org/wiki/Q10364247', 'display_name': 'Rhomboid', 'level': 4, 'score': 0.43806458}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.43064323}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.4010476}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.34225845}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.33954784}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.108466595}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.100202024}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.06293595}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016786', 'descriptor_name': 'Eimeria tenella', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D016786', 'descriptor_name': 'Eimeria tenella', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D010447', 'descriptor_name': 'Peptide Hydrolases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002432', 'descriptor_name': 'Cecum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002432', 'descriptor_name': 'Cecum', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D002645', 'descriptor_name': 'Chickens', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D002645', 'descriptor_name': 'Chickens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003048', 'descriptor_name': 'Coccidiosis', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D003048', 'descriptor_name': 'Coccidiosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016786', 'descriptor_name': 'Eimeria tenella', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D016786', 'descriptor_name': 'Eimeria tenella', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018503', 'descriptor_name': 'Genome, Protozoan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015698', 'descriptor_name': 'Genomic Library', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052940', 'descriptor_name': 'Merozoites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052940', 'descriptor_name': 'Merozoites', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D033661', 'descriptor_name': 'Oocysts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D033661', 'descriptor_name': 'Oocysts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010447', 'descriptor_name': 'Peptide Hydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010447', 'descriptor_name': 'Peptide Hydrolases', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D010447', 'descriptor_name': 'Peptide Hydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 9, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1471-2164-13-685', 'pdf_url': 'https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/1471-2164-13-685', 'source': {'id': 'https://openalex.org/S28614077', 'display_name': 'BMC Genomics', 'issn_l': '1471-2164', 'issn': ['1471-2164'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.inrae.fr/hal-02646603', 'pdf_url': 'https://hal.inrae.fr/hal-02646603/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3770453', 'pdf_url': 'https://europepmc.org/articles/pmc3770453?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.inrae.fr/hal-02646603/file/BMC_Genomics_2012_vol13_p685_1.pdf', 'pdf_url': 'https://hal.inrae.fr/hal-02646603/file/BMC_Genomics_2012_vol13_p685_1.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://researchonline.rvc.ac.uk/id/eprint/7384/', 'pdf_url': 'https://rvc-repository.worktribe.com/preview/1650598/Vet%20Record%20Case%20Reports%20-%202023%20-%20Lang.pdf', 'source': {'id': 'https://openalex.org/S4306402069', 'display_name': 'RVC Research Online (Royal Veterinary College)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I133836048', 'host_organization_name': 'Royal Veterinary College', 'host_organization_lineage': ['https://openalex.org/I133836048'], 'host_organization_lineage_names': ['Royal Veterinary College'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10453/117997', 'pdf_url': 'https://opus.lib.uts.edu.au/bitstream/10453/117997/1/Stage-specific%20expression%20of%20protease%20genes%20in%20the%20apicomplexan%20parasite%2c%20Eimeria%20tenella.pdf', 'source': {'id': 'https://openalex.org/S4377196279', 'display_name': 'OPUS - Open Publications of UTS Scholars (University of Technology Sydney)', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I114017466', 'host_organization_name': 'University of Technology Sydney', 'host_organization_lineage': ['https://openalex.org/I114017466'], 'host_organization_lineage_names': ['University of Technology Sydney'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770453', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://researchonline.jcu.edu.au/26323/1/26323_Katrib_etal_2012.pdf', 'pdf_url': 'https://researchonline.jcu.edu.au/26323/1/26323_Katrib_etal_2012.pdf', 'source': {'id': 'https://openalex.org/S4306400520', 'display_name': 'ResearchOnline at James Cook University (James Cook University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I86467917', 'host_organization_name': 'James Cook University', 'host_organization_lineage': ['https://openalex.org/I86467917'], 'host_organization_lineage_names': ['James Cook University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23216867', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1471-2164-13-685', 'pdf_url': 'https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/1471-2164-13-685', 'source': {'id': 'https://openalex.org/S28614077', 'display_name': 'BMC Genomics', 'issn_l': '1471-2164', 'issn': ['1471-2164'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/15', 'score': 0.53, 'display_name': 'Life on land'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 40, 'referenced_works': ['https://openalex.org/W1884908391', 'https://openalex.org/W1902537869', 'https://openalex.org/W1973020628', 'https://openalex.org/W1974737426', 'https://openalex.org/W1978339551', 'https://openalex.org/W1983847354', 'https://openalex.org/W1991908351', 'https://openalex.org/W1997298397', 'https://openalex.org/W1997887845', 'https://openalex.org/W2001279976', 'https://openalex.org/W2007889771', 'https://openalex.org/W2016823905', 'https://openalex.org/W2020029765', 'https://openalex.org/W2020335167', 'https://openalex.org/W2035420326', 'https://openalex.org/W2042567314', 'https://openalex.org/W2048639963', 'https://openalex.org/W2053327286', 'https://openalex.org/W2055043387', 'https://openalex.org/W2061152336', 'https://openalex.org/W2066104894', 'https://openalex.org/W2069310601', 'https://openalex.org/W2072501163', 'https://openalex.org/W2082073529', 'https://openalex.org/W2084212675', 'https://openalex.org/W2085368314', 'https://openalex.org/W2085827012', 'https://openalex.org/W2087701580', 'https://openalex.org/W2090160626', 'https://openalex.org/W2100837269', 'https://openalex.org/W2108992097', 'https://openalex.org/W2115693568', 'https://openalex.org/W2141885858', 'https://openalex.org/W2147552637', 'https://openalex.org/W2156022009', 'https://openalex.org/W2157008176', 'https://openalex.org/W2163524749', 'https://openalex.org/W4246995357', 'https://openalex.org/W4320301318', 'https://openalex.org/W4320800236'], 'related_works': ['https://openalex.org/W4386466540', 'https://openalex.org/W4231501745', 'https://openalex.org/W4221101883', 'https://openalex.org/W2598083330', 'https://openalex.org/W2566796086', 'https://openalex.org/W241123873', 'https://openalex.org/W2274635334', 'https://openalex.org/W2109961287', 'https://openalex.org/W2068759727', 'https://openalex.org/W2062305867'], 'abstract_inverted_index': {'Abstract': [0], 'Background': [1], 'Proteases': [2], 'regulate': [3], 'pathogenesis': [4], 'in': [5, 33, 37, 67, 96, 106, 113, 128, 134, 146, 208, 241], 'apicomplexan': [6], 'parasites': [7], 'but': [8], 'investigations': [9], 'of': [10, 20, 88, 100, 131, 137, 160, 169, 197, 201, 203, 213, 216, 227, 244, 251, 254], 'proteases': [11, 32, 139], 'have': [12], 'been': [13], 'largely': [14], 'confined': [15, 223], 'to': [16, 103, 180, 224, 230, 233], 'the': [17, 38, 43, 68, 147, 157, 187, 234, 242, 245], 'asexual': [18, 209], 'stages': [19], 'Plasmodium': [21], 'falciparum': [22, 115], 'and': [23, 54, 83, 111, 141, 152, 236], 'Toxoplasma': [24], 'gondii': [25, 118], '.': [26, 119], 'Thus,': [27], 'little': [28], 'is': [29, 206, 219], 'known': [30, 102], 'about': [31], 'other': [34], 'Apicomplexa,': [35], 'particularly': [36], 'sexual': [39], 'stages.': [40, 210], 'We': [41], 'screened': [42], 'Eimeria': [44, 191], 'tenella': [45, 70, 151, 175, 192], 'genome': [46], 'database': [47], 'for': [48], 'proteases,': [49], 'classified': [50], 'these': [51, 132, 204, 228], 'into': [52, 186], 'families': [53, 136], 'determined': [55], 'their': [56, 161], 'stage': [57], 'specific': [58], 'expression.': [59], 'Results': [60], 'Over': [61], 'forty': [62], 'protease': [63, 92, 121, 165, 198, 217], 'genes': [64, 93, 101, 122, 205, 218], 'were': [65, 73, 123, 133], 'identified': [66], 'E.': [69, 150, 174], 'genome.': [71], 'These': [72], 'distributed': [74], 'across': [75], 'aspartic': [76], '(three': [77], 'genes),': [78], 'cysteine': [79], '(sixteen),': [80], 'metallo': [81], '(fourteen)': [82], 'serine': [84, 138], '(twelve)': [85], 'proteases.': [86], 'Expression': [87, 200], 'at': [89], 'least': [90], 'fifteen': [91], 'was': [94], 'upregulated': [95, 127, 207, 220], 'merozoites': [97], 'including': [98], 'homologs': [99], 'be': [104, 231], 'important': [105], 'host': [107], 'cell': [108], 'invasion,': [109], 'remodelling': [110], 'egress': [112], 'P.': [114], 'and/or': [116], 'T.': [117, 153], 'Thirteen': [120], 'specifically': [124], 'expressed': [125], 'or': [126, 222], 'gametocytes;': [129, 225], 'five': [130], 'two': [135], '(S1': [140], 'S8)': [142], 'that': [143, 177, 183], 'are': [144, 184], 'over-represented': [145], 'coccidian': [148], 'parasites,': [149], 'gondii,': [154], 'distinctive': [155], 'within': [156], 'Apicomplexa': [158], 'because': [159], 'hard-walled': [162], 'oocysts.': [163], 'Serine': [164], 'inhibitors': [166], 'prevented': [167], 'processing': [168], 'EtGAM56,': [170], 'a': [171, 194, 248], 'protein': [172], 'from': [173], 'gametocytes': [176], 'gives': [178], 'rise': [179], 'tyrosine-rich': [181], 'peptides': [182], 'incorporated': [185], 'oocyst': [188, 246], 'wall.': [189], 'Conclusion': [190], 'possesses': [193], 'large': [195], 'number': [196], 'genes.': [199], 'many': [202], 'However,': [211], 'expression': [212], 'almost': [214], 'one-third': [215], 'in,': [221], 'some': [226], 'appear': [229], 'unique': [232], 'Coccidia': [235], 'may': [237], 'play': [238], 'key': [239], 'roles': [240], 'formation': [243], 'wall,': [247], 'defining': [249], 'feature': [250], 'this': [252], 'group': [253], 'parasites.': [255]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2027368040', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-09-09T02:56:32.328615', 'created_date': '2016-06-24'}