Title: Convenient Multigram Synthesis of (<i>R</i>)-Homopipecolic Acid Methyl Ester
Abstract: (R)-Homopipecolic acid methyl ester has been prepared on a multigram scale from 3,4-dihydro-2H-pyran in five steps and 36% overall yield. The stereochemistry was introduced via an asymmetric Michael addition and a fractional crystallization.
Publication Year: 2006
Publication Date: 2006-04-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 6
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