Publication Information

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4520, 4643, 4933], 'in': [10, 35, 55, 87, 180, 205, 225, 257, 538, 599, 618, 636, 741, 807, 874, 1016, 1078, 1148, 1233, 1238, 1270, 1494, 1516, 1677, 1701, 1780, 1798, 1974, 2050, 2093, 2132, 2234, 2246, 2267, 2300, 2360, 2444, 2624, 2659, 2669, 2743, 2765, 2853, 2872, 2877, 2887, 2931, 3097, 3110, 3151, 3203, 3245, 3283, 3318, 3335, 3362, 3370, 3381, 3402, 3427, 3479, 3488, 3500, 3537, 3569, 3580, 3632, 3669, 3769, 3775, 3782, 4034, 4057, 4169, 4358, 4490, 4626, 4797, 4934, 5023, 5038, 5071, 5078, 5083, 5087, 5258, 5276, 5337, 5438, 5481, 5493, 5505, 5542, 5554, 5610, 5613, 5675, 5685, 5704, 5741, 5756, 5807, 5813, 5857, 5865, 5962], 'vitro': [11, 181, 5611], 'on': [12, 80, 182, 250, 1140, 1363, 1440, 1851, 1882, 2088, 2211, 2257, 2314, 2414, 2461, 2496, 2572, 2599, 2652, 2839, 2894, 2909, 3148, 3180, 3274, 3684, 4041, 4152, 4383, 4449, 4590, 4644, 4720, 4776, 4792, 4856, 5527, 5628], 'amphoterin-coated': [13, 81, 183, 251, 1141, 1441, 2499, 2589, 3685, 4042], 'substrates.': [14, 82, 184, 252, 1142, 1442], 'Ligation': [15, 185], 'of': [16, 45, 69, 76, 85, 100, 106, 110, 126, 136, 186, 215, 239, 246, 255, 270, 276, 280, 296, 306, 387, 391, 514, 525, 591, 602, 608, 613, 620, 623, 639, 736, 813, 854, 871, 1027, 1132, 1137, 1245, 1253, 1257, 1272, 1278, 1370, 1376, 1396, 1447, 1463, 1474, 1512, 1520, 1528, 1539, 1626, 1667, 1683, 1757, 1822, 1836, 1841, 1957, 2010, 2017, 2198, 2206, 2215, 2294, 2373, 2405, 2424, 2457, 2503, 2508, 2544, 2569, 2681, 2691, 2695, 2701, 2710, 2720, 2733, 2740, 2835, 2860, 2882, 2899, 2915, 2933, 3005, 3090, 3102, 3108, 3132, 3154, 3173, 3213, 3221, 3235, 3289, 3312, 3331, 3355, 3367, 3392, 3399, 3413, 3422, 3430, 3443, 3503, 3509, 3605, 3610, 3640, 3680, 3733, 4064, 4069, 4258, 4330, 4337, 4366, 4370, 4390, 4397, 4418, 4427, 4453, 4456, 4469, 4485, 4515, 4584, 4593, 4633, 4649, 4669, 4679, 4702, 4741, 4773, 4780, 4800, 4807, 4852, 4921, 4938, 4955, 4987, 5003, 5006, 5019, 5029, 5034, 5045, 5109, 5114, 5194, 5202, 5217, 5256, 5269, 5325, 5351, 5360, 5393, 5398, 5402, 5408, 5441, 5488, 5499, 5557, 5564, 5583, 5590, 5607, 5624, 5632, 5638, 5642, 5647, 5679, 5717, 5731, 5748, 5810, 5899, 5905, 5917, 5930, 5938, 5942, 5965, 5973, 6025], 'RAGE': [17, 52, 70, 86, 159, 187, 222, 240, 256, 329, 475, 797, 856, 1075, 1133, 1145, 1178, 1226, 1246, 1254, 1354, 1449, 1464, 1542, 1575, 1758, 1767, 2374, 2393, 2451, 2545, 2559, 2682, 2854, 2916, 3135, 3214, 3228, 3236, 3393, 3526, 4031, 4048, 4246, 4338, 4352, 4372, 4391, 4428, 4627, 4988, 5009, 5039, 5115, 5403, 5442, 5482, 5491, 5633, 5643, 5705, 5742, 5918, 5932, 5989], 'by': [18, 104, 129, 140, 158, 188, 274, 299, 310, 328, 791, 857, 1358, 1368, 1499, 1535, 1563, 1688, 1761, 1791, 1955, 2001, 2014, 2048, 2060, 2069, 2265, 2277, 3058, 3299, 4250, 4328, 4651, 4944, 5486, 5578, 5586], 'two': [19, 189, 1529, 2919, 4066, 5409, 5708], 'other': [20, 190, 2920, 3130, 4067, 5032, 5342, 5757, 5949], 'ligands,': [21, 191, 1261, 2921], 'or': [26, 147, 196, 317, 360, 1129, 1263, 1367, 2074, 2394, 2421, 2483, 2517, 2549, 2663, 2862, 2864, 2885, 3166, 3197, 3229, 3279, 3507, 3516, 3560, 3613, 4327, 4433, 4705, 5031, 5120, 5561, 5719], 'amyloid': [27, 197, 737, 784, 804, 858, 1157, 1264, 2924, 3407, 4073, 4254, 5121, 5261, 5924, 5945], 'β-peptide,': [28, 198, 1265, 2925, 4255, 5925], 'is': [29, 138, 199, 308, 384, 914, 1013, 1247, 1266, 1349, 1427, 1434, 1465, 2603, 2683, 2704, 3215, 3394, 3410, 3567, 3730, 4154, 4242, 4377, 4406, 4413, 4462, 4504, 4658, 4708, 4783, 4928, 4957, 4978, 5052, 5068, 5111, 5322, 5332, 5380, 5484, 5626, 5673, 5697, 5745, 5912, 5935, 6031], 'suggested': [30, 200, 595, 1171, 1267, 4617], 'to': [31, 71, 160, 201, 241, 330, 596, 631, 750, 801, 863, 869, 1162, 1172, 1268, 1382, 1392, 1506, 1730, 1742, 1749, 1810, 2192, 2251, 2322, 2368, 2434, 2534, 2618, 2661, 2706, 2844, 2917, 2929, 3012, 3053, 3056, 3404, 3418, 3439, 3485, 3490, 3539, 3591, 3677, 3771, 3778, 4323, 4349, 4373, 4379, 4408, 4415, 4439, 4481, 4595, 4665, 4710, 4930, 4969, 4973, 4980, 4999, 5008, 5055, 5064, 5199, 5214, 5260, 5266, 5341, 5355, 5357, 5490, 5598, 5714, 5805], 'play': [32, 202, 632], 'a': [33, 203, 385, 477, 512, 621, 633, 865, 915, 1079, 1228, 1384, 1524, 1545, 1589, 1603, 1618, 1637, 1647, 1651, 1674, 1770, 1781, 1858, 1868, 2361, 2376, 2391, 2395, 2501, 2621, 2629, 2865, 2906, 3014, 3103, 3159, 3167, 3177, 3310, 3660, 3670, 3731, 4035, 4050, 4170, 4355, 4359, 4393, 4401, 4431, 4435, 4450, 4466, 4738, 4924, 4990, 5112, 5387, 5434, 5451, 5521, 5690, 5858], 'role': [34, 204, 635, 2372, 3421, 4389, 5018], 'cell': [36, 59, 206, 229, 401, 788, 1243, 1365, 1371, 2387, 2440, 3297, 3547, 4325, 4331, 5207, 5559], 'injury': [37, 60, 207, 230, 5076, 5972], 'mechanisms': [38, 208, 1369, 4329, 5934], 'involving': [39, 209], 'cellular': [40, 210, 808, 1273, 2934, 3006, 4161], 'oxidant': [41, 211, 809, 1274, 1356, 1377, 2935, 3007, 3059, 4162, 4248], 'stress': [42, 212, 810, 1275, 1357, 1378, 2721, 2936, 3008, 3060, 4163, 4249, 5058], 'and': [43, 58, 78, 98, 116, 164, 213, 228, 248, 268, 286, 334, 394, 509, 527, 533, 627, 811, 1019, 1081, 1144, 1156, 1237, 1276, 1472, 1490, 1514, 1572, 1576, 1600, 1655, 1694, 1712, 1716, 1833, 1864, 1880, 1892, 1896, 1992, 2091, 2108, 2134, 2179, 2224, 2241, 2249, 2317, 2358, 2411, 2523, 2620, 2687, 2723, 2730, 2735, 2767, 2923, 3123, 3192, 3270, 3325, 3348, 3401, 3406, 3474, 3527, 3566, 3599, 3636, 3655, 3765, 3786, 4044, 4047, 4052, 4072, 4164, 4253, 4636, 4744, 4787, 4818, 4854, 5021, 5057, 5077, 5545, 5612, 5634, 5653, 5702, 5737, 5753, 5919, 5926, 5944, 5954, 6004, 6008, 6010, 6028], 'activation': [44, 99, 135, 214, 269, 305, 812, 870, 1277, 1473, 1519, 3220, 3354, 3398, 3502, 3604, 3635, 5193, 5255, 5350, 5392, 5495, 5498, 5529, 5589, 5606, 5623, 5646, 5678, 5716, 5809, 5864, 5904], 'the': [46, 51, 94, 107, 124, 134, 216, 221, 264, 277, 294, 304, 388, 399, 600, 637, 742, 1017, 1024, 1149, 1174, 1241, 1258, 1279, 1364, 1393, 1444, 1448, 1460, 1484, 1495, 1510, 1517, 1536, 1568, 1577, 1678, 1731, 1743, 1751, 1765, 1775, 1799, 1853, 1874, 2015, 2125, 2194, 2207, 2235, 2329, 2371, 2399, 2439, 2449, 2474, 2535, 2539, 2555, 2596, 2677, 2689, 2692, 2696, 2711, 2718, 2731, 2738, 2832, 2847, 2900, 2918, 3129, 3133, 3152, 3210, 3226, 3230, 3296, 3301, 3336, 3353, 3371, 3389, 3419, 3428, 3431, 3510, 3528, 3626, 3633, 3643, 3647, 3734, 3776, 3783, 4058, 4065, 4324, 4334, 4363, 4367, 4388, 4416, 4424, 4486, 4516, 4585, 4596, 4619, 4640, 4667, 4670, 4677, 4721, 4770, 4777, 4793, 4849, 4857, 4974, 5017, 5046, 5189, 5215, 5273, 5358, 5396, 5399, 5406, 5439, 5528, 5540, 5555, 5562, 5580, 5588, 5600, 5621, 5629, 5639, 5645, 5657, 5669, 5676, 5715, 5729, 5734, 5738, 5808, 5915, 5931, 5939, 5948, 5955, 5963, 5966, 5974, 5987, 5998], 'transcription': [47, 217, 1280, 3291, 3334, 3357, 3369, 3445, 4166, 5049, 5649], 'factor': [48, 218, 1281, 4167, 5271], 'NF-κB.': [49, 169, 219, 339, 3415, 3504, 3641, 5394, 5500, 5680], 'However,': [50, 220, 1373, 1502, 4399, 4768, 5330, 5444, 5655, 5722], 'signaling': [53, 154, 223, 324, 1432, 1450, 1525, 2770, 3136, 4335, 4356, 4436, 4509, 4723, 4971, 5040, 5695, 5933, 5957], 'pathways': [54, 155, 224, 325, 1531, 3650, 5711, 5740, 5755], 'are': [61, 102, 156, 231, 272, 326, 1146, 1159, 1452, 1492, 2230, 2851, 3095, 3138, 3201, 3476, 3497, 3630, 4447, 4477, 4511, 4842], 'largely': [62, 232], 'unknown.': [63, 233, 1453], 'Here': [64, 234], 'we': [65, 235, 1457, 1503, 2382, 2842, 3224, 3483, 5318, 5509, 5618, 5662], 'show': [66, 236, 1479, 5619], 'that': [67, 152, 237, 322, 1388, 1459, 1480, 1523, 2582, 2759, 3128, 3189, 3388, 3622, 4030, 4045, 4361, 4423, 4507, 4618, 4717, 4731, 4785, 4918, 4950, 4964, 5066, 5320, 5334, 5382, 5478, 5571, 5620, 5664, 5689, 5893], 'transfection': [68, 238, 1748], 'neuroblastoma': [72, 242, 1692, 2386, 4375], 'cells': [73, 89, 243, 259, 873, 1693, 1698, 1722, 1788, 1797, 1854, 1875, 2045, 2126, 2200, 2252, 2262, 2295, 2330, 2336, 2408, 2447, 2472, 2485, 2505, 2519, 2536, 2556, 2597, 2650, 2665, 2668, 2837, 2889, 3112, 3145, 3306, 3337, 3372, 3522, 3543, 3581, 4153, 4376, 4410, 4446, 4588, 4775, 4936, 5867], 'induces': [74, 244, 786, 1355, 4247], 'extension': [75, 125, 245, 295, 4040, 4455, 4678, 5953], 'filopodia': [77, 247, 2460, 2741, 4458], 'neurites': [79, 127, 249, 297, 2510, 2526, 2571, 4461, 4680], 'Furthermore,': [83, 253, 1126], 'ligation': [84, 254, 853, 1252, 5116], 'transfected': [88, 258, 1724, 1753, 1790, 2537, 3338, 3373, 3519, 4407], 'enhances': [90, 260], 'NF-κB-dependent': [91, 261, 1475, 3290, 3333, 3356, 3368, 3574, 3606, 5591, 5648], 'transcription.': [92, 262, 1476, 5592], 'Both': [93, 263, 4157], 'RAGE-mediated': [95, 265, 1374, 1437, 1469, 1518, 2583, 2910, 3003, 3098, 3116, 3141, 3181, 3204, 3219, 3480, 3501, 3634, 4641, 4712, 5024, 5192, 5254, 5391, 5605, 5622, 5677, 5903], 'NF-κB': [101, 137, 271, 307, 814, 1282, 1397, 1521, 1679, 3449, 4168, 5067, 5110, 5195, 5257, 5327, 5352, 5516, 5530, 5584, 5608, 5625, 5718, 5863, 5906], 'blocked': [103, 273, 2128, 4639, 5644], 'deletion': [105, 275, 1579, 2396, 2476, 2542, 3233, 4404], 'cytoplasmic': [108, 278, 1461, 1537, 1557, 1578, 2400, 2475, 2540, 2693, 3211, 3231, 3390, 4364, 4402, 4425, 4985, 5010, 5630, 5640], 'domain': [109, 279, 1462, 1538, 1558, 1666, 2401, 2541, 2694, 3212, 3232, 3391, 4365, 4403, 4426, 4986, 5011, 5631, 5641], 'RAGE.': [111, 281, 1540, 2406, 3341, 5329], 'Moreover,': [112, 282, 852, 1443, 3047], 'dominant': [113, 120, 141, 283, 290, 311, 3104, 3511, 3586, 4630, 5658, 6005, 6018], 'negative': [114, 121, 142, 284, 291, 312, 1843, 2857, 3105, 3512, 3587, 4631, 5659, 6006, 6019], 'Rac': [115, 146, 285, 316, 1489, 1513, 2726, 2861, 3191, 3473, 4635, 4704, 4735, 4745, 4788, 4817, 4853, 5020, 5035, 5801, 5894, 6007], 'Cdc42': [117, 287, 1491, 1515, 2736, 2863, 3193, 3475, 3614, 4637, 4706, 4732, 4743, 4786, 4819, 4855, 5022, 5037], 'but': [118, 144, 288, 314, 1483, 3194, 3624, 5081, 5523, 5585, 5667, 5707, 5855], 'not': [119, 145, 289, 315, 1160, 1248, 1351, 1428, 1481, 2490, 2904, 3114, 3195, 3377, 3625, 5537, 5577, 5668, 5726], 'Ras': [122, 143, 292, 313, 1482, 3057, 3588, 3623, 5666, 5752], 'inhibit': [123, 293, 3592], 'induced': [128, 298, 1498], 'RAGE-amphoterin': [130, 300, 1500], 'interaction.': [131, 301, 1501], 'In': [132, 302, 587, 732, 1454, 2366, 2514, 2532, 2714, 3416, 4343, 4725, 5188, 5252, 5315, 5514, 5615, 5799], 'contrast,': [133, 303, 2515], 'inhibited': [139, 309, 3579], 'Cdc42.': [148, 318], 'These': [149, 319, 1628, 2407, 3186, 3619], 'data': [150, 320, 3187, 3620], 'suggest': [151, 321], 'distinct': [153, 323], 'used': [157, 327, 1672, 2191, 2245, 3253, 3308, 5504, 5511], 'induce': [161, 331, 4380, 4931, 5200, 5267, 5385], 'regulate': [165, 335, 2707, 5896], 'gene': [166, 336, 3242, 3531, 5338, 5404], 'expression': [167, 337, 1585, 1634, 1756, 2898, 3257, 4055, 5201, 5268, 5339, 5483, 5999], 'through': [168, 338, 4736, 5328, 5390], 'receptor': [340, 377, 2379, 4357, 4396], 'heparin-binding': [350], 'growth-associated': [351], 'molecule': [352, 403, 2867, 4432], 'phosphatidylinositol': [353, 3048], '3-kinase': [354, 3049, 3169], 'mitogen': [355], 'activated': [356, 1534], 'protein': [357, 919, 2607], 'kinase': [358, 363, 364, 375, 1386, 3017, 3093, 3162, 3199, 4804, 4940, 5736], 'MAP': [359, 3016], 'extracellular': [361, 3780], 'signal-related': [362], 'N,N-bis(2-hydroxyethyl)-2-aminoethanesulfonic': [365], 'acid': [366], 'bovine': [367, 1950, 2102, 2309], 'serum': [368, 1951, 2103, 2310], 'albumin': [369, 1952, 2104, 2311], 'phosphate-buffered': [370], 'saline': [371], 'tetramethylrhodamine': [372], 'isothiocyanate': [373], 'p21-activated': [374, 4803], 'The': [376, 606, 1251, 1556, 1593, 1613, 1641, 1681, 1755, 1996, 2008, 2151, 2196, 2335, 2698, 2913, 3287, 3365, 3533, 3573, 3585, 4062, 4581, 4802, 4984, 5027, 5681, 6021], '(RAGE)1': [383], 'member': [386, 3732], 'immunoglobulin': [389], 'superfamily': [390], 'cell-surface': [392, 615, 794], 'molecules': [393, 4510, 5004], 'shares': [395], 'closest': [396], 'homology': [397], 'with': [398, 511, 610, 745, 793, 803, 1255, 1659, 1707, 1725, 1819, 1857, 1878, 1964, 2071, 2110, 2118, 2129, 2142, 2156, 2170, 2232, 2286, 2418, 2432, 2464, 2538, 2595, 2608, 3238, 3263, 3280, 3339, 3374, 3524, 3553, 3583, 4430, 5117, 5533, 5651, 5986, 5997, 6017], 'neural': [400, 5967], 'adhesion': [402, 5208], 'NCAM': [404], '(1Schmidt': [405, 4075], 'A.-M.': [406, 4076], 'Vianna': [407, 4077], 'M.': [408, 410, 424, 446, 496, 541, 563, 575, 645, 822, 832, 948, 997, 1097, 1192, 1290, 1300, 1912, 2944, 2954, 3700, 3750, 3812, 3861, 3939, 3945, 3961, 3963, 3968, 4000, 4078, 4080, 4094, 4122, 4132, 4180, 4190, 4298, 4300, 5130, 5140], 'Gerlach': [409, 4079], 'Brett': [411, 449, 654, 1086, 1181, 1328, 2982, 3689, 3989, 4081, 4218, 4271, 5168, 5237], 'J.': [412, 414, 416, 433, 450, 463, 482, 502, 548, 565, 651, 655, 695, 820, 834, 882, 929, 944, 953, 965, 969, 971, 974, 987, 991, 1000, 1034, 1050, 1065, 1087, 1093, 1105, 1110, 1182, 1188, 1200, 1205, 1288, 1302, 1327, 1329, 1336, 1410, 1902, 1906, 1915, 1932, 1937, 2031, 2942, 2956, 2981, 2983, 2990, 3031, 3069, 3690, 3696, 3708, 3713, 3740, 3744, 3753, 3793, 3808, 3817, 3829, 3833, 3835, 3838, 3851, 3855, 3864, 3880, 3895, 3909, 3990, 3996, 4008, 4013, 4082, 4084, 4086, 4103, 4120, 4134, 4178, 4192, 4217, 4219, 4226, 4270, 4272, 4279, 4759, 4869, 4882, 4908, 5128, 5142, 5167, 5169, 5176, 5230, 5232, 5238, 5241, 5284, 5371, 5414, 5417, 5456, 5461, 5790], 'Ryan': [413, 4083], 'Kao': [415, 4085], 'Esposito': [417, 4087], 'C.': [418, 430, 498, 680, 768, 4088, 4100, 4755, 4867, 5092], 'Hegarty': [419, 4089], 'H.': [420, 545, 824, 880, 926, 942, 973, 999, 1031, 1292, 1914, 1936, 2030, 2634, 2946, 3752, 3790, 3806, 3837, 3863, 4090, 4124, 4182, 4825, 5132, 5282, 5778], 'Hurley': [421, 4091], 'W.': [422, 4092], 'Clauss': [423, 4093], 'Wang': [425, 453, 4095], 'F.': [426, 454, 4096], 'Pan': [427, 455, 4097], 'Y.-C.E.': [428, 4098], 'Tsang': [429, 4099], 'Stern': [431, 459, 691, 718, 839, 894, 1106, 1201, 1307, 1334, 2961, 2988, 3709, 4009, 4101, 4139, 4197, 4224, 4277, 5147, 5174, 5239, 5296, 5981], 'D.': [432, 460, 492, 647, 692, 719, 840, 895, 1103, 1107, 1198, 1202, 1308, 1333, 1335, 2962, 2987, 2989, 3706, 3710, 4006, 4010, 4102, 4140, 4198, 4223, 4225, 4276, 4278, 5148, 5173, 5175, 5240, 5297], 'Biol.': [434, 464, 930, 955, 975, 1001, 1035, 1052, 1111, 1206, 1337, 1411, 1916, 1938, 2033, 2802, 2991, 3032, 3070, 3714, 3754, 3794, 3819, 3839, 3865, 3882, 4014, 4104, 4227, 4280, 4552, 4691, 4885, 5177, 5418, 5462, 5882], 'Chem.': [435, 465, 931, 976, 1002, 1036, 1112, 1207, 1338, 1412, 1917, 1939, 2992, 3033, 3071, 3715, 3755, 3795, 3840, 3866, 4015, 4105, 4228, 4281, 5178, 5419, 5463], '1992;': [436, 466, 566, 1940, 4106], '267:': [437, 467, 1941, 4107], '14987-14997Abstract': [438, 4108], 'Full': [439, 469, 775, 935, 980, 1006, 1040, 1116, 1118, 1211, 1213, 1342, 1416, 1418, 1921, 1943, 2821, 2823, 2996, 3037, 3039, 3075, 3077, 3719, 3721, 3759, 3799, 3844, 3870, 4019, 4021, 4109, 4232, 4285, 4571, 4573, 4609, 4889, 5098, 5100, 5182, 5423, 5425, 5467, 5469, 5767], 'Text': [440, 470, 776, 936, 981, 1007, 1041, 1117, 1119, 1212, 1214, 1343, 1417, 1419, 1922, 1944, 2822, 2824, 2997, 3038, 3040, 3076, 3078, 3720, 3722, 3760, 3800, 3845, 3871, 4020, 4022, 4110, 4233, 4286, 4572, 4574, 4610, 4890, 5099, 5101, 5183, 5424, 5426, 5468, 5470, 5768], 'PDF': [441, 471, 777, 937, 982, 1008, 1042, 1120, 1215, 1344, 1420, 1923, 1945, 2825, 2998, 3041, 3079, 3723, 3761, 3801, 3846, 3872, 4023, 4111, 4234, 4287, 4575, 4611, 4891, 5102, 5184, 5427, 5471, 5769], 'PubMed': [442, 472, 553, 569, 582, 672, 701, 727, 762, 778, 847, 908, 938, 959, 983, 1009, 1043, 1056, 1070, 1121, 1216, 1315, 1345, 1421, 1924, 1946, 2037, 2644, 2751, 2787, 2806, 2826, 2969, 2999, 3042, 3080, 3467, 3724, 3762, 3802, 3823, 3847, 3873, 3886, 3900, 3914, 3933, 3955, 3979, 4024, 4112, 4147, 4205, 4235, 4288, 4317, 4498, 4537, 4556, 4576, 4612, 4695, 4763, 4834, 4874, 4892, 4912, 5103, 5155, 5185, 5247, 5310, 5376, 5428, 5472, 5770, 5794, 5831, 5850, 5886], 'Google': [443, 473, 507, 556, 572, 585, 675, 704, 730, 765, 781, 850, 911, 939, 962, 984, 1010, 1044, 1059, 1073, 1124, 1219, 1318, 1346, 1424, 1925, 1947, 2040, 2647, 2754, 2790, 2809, 2829, 2972, 3000, 3045, 3083, 3470, 3727, 3763, 3803, 3826, 3848, 3874, 3889, 3903, 3917, 3936, 3958, 3982, 4027, 4113, 4150, 4208, 4236, 4289, 4320, 4501, 4540, 4559, 4579, 4615, 4698, 4766, 4837, 4877, 4895, 4915, 5106, 5158, 5186, 5250, 5313, 5377, 5431, 5475, 5773, 5797, 5834, 5853, 5887], 'Scholar,': [444, 557, 573, 676, 705, 766, 940, 963, 985, 1045, 1060, 1319, 1926, 2791, 2810, 2973, 3804, 3827, 3849, 3875, 3890, 3904, 3918, 3937, 3959, 4114, 4209, 4290, 4541, 4560, 4878, 5159, 5774, 5835], '2Neeper': [445], 'Schmidt': [447, 483, 693, 720, 841, 896, 1108, 1203, 1309, 1322, 1408, 2963, 2976, 3029, 3711, 4011, 4141, 4199, 4212, 4265, 5149, 5162, 5298, 5415, 5459], 'A.M.': [448, 484, 643, 694, 721, 842, 897, 1109, 1204, 1310, 1323, 1409, 2964, 2977, 3030, 3712, 4012, 4142, 4200, 4213, 4266, 5150, 5163, 5222, 5299, 5416, 5460], 'Yan': [451, 485, 652, 883, 5235, 5285], 'S.D.': [452, 486, 653, 816, 1284, 1321, 2938, 2975, 4116, 4174, 4211, 4264, 5124, 5161, 5236], 'Y.C.': [456], 'Elliston': [457], 'K.': [458, 659, 2814, 4292, 4564, 5871], 'Shaw': [461, 499, 5785], 'A.': [462, 500, 543, 668, 826, 836, 886, 904, 1294, 1304, 2746, 2816, 2948, 2958, 3941, 4126, 4136, 4184, 4194, 4313, 4493, 4566, 4604, 4747, 5134, 5144, 5288, 5306, 5762, 5816, 5820], '14998-15004Abstract': [468], 'Scholar).': [474, 586, 731, 782, 851, 912, 1011, 1074, 1125, 1220, 1347, 1425, 1948, 2041, 2648, 2755, 2830, 3001, 3046, 3084, 3471, 3728, 3983, 4237, 4502, 4580, 4699, 4767, 4838, 4896, 5107, 5187, 5251, 5314, 5378, 5798, 5888], 'exhibits': [476], 'wide': [478], 'tissue': [479, 1884, 2319], 'distribution': [480], '(3Brett': [481], 'Zou': [487, 1330, 2984, 4220, 4273, 5170], 'Y.S.': [488, 878, 1331, 2985, 4221, 4274, 5171, 5280], 'Weidman': [489], 'E.': [490, 989, 1904, 1928, 3742, 3853, 3947, 3972, 4751, 4821, 4863, 5818], 'Pinsky': [491, 1332, 2986, 4222, 4275, 5172], 'Nowygrod': [493], 'R.': [494, 657, 688, 928, 946, 967, 993, 1033, 1091, 1186, 1908, 1934, 2793, 2812, 3451, 3459, 3694, 3746, 3792, 3810, 3831, 3857, 3994, 4543, 4562, 4682, 5234], 'Neeper': [495], 'Przysiecki': [497], 'Am.': [501], 'Pathol.': [503], '1993;': [504, 772, 1003, 1918, 3756, 3867], '143:': [505], '1699-1712PubMed': [506], 'Scholar)': [508, 3764, 4028, 4616, 4916, 5432, 5476, 5854], 'interacts': [510, 4429], 'range': [513], 'ligands.': [515], 'Advanced': [516], '(AGE)': [520], 'resulting': [521, 806, 5492], 'from': [522, 921, 1548, 1606, 1621, 3295, 3546], 'nonenzymatic': [523], 'proteins': [526, 3738, 4972], 'lipids': [528], 'accumulate': [529, 5065], 'during': [530, 1023, 5969], 'normal': [531, 1800], 'aging': [532], 'at': [534, 1861, 1871, 1968, 2079, 2139], 'an': [535, 1656, 1811, 3156, 3239, 3550, 4951, 5890], 'accelerated': [536], 'rate': [537], 'diabetes': [539], '(4Brownlee': [540], 'Cerami': [542], 'Vlassara': [544], 'N.': [546, 1049, 1064, 3879, 3894, 5784, 5822], 'Engl.': [547], 'Med.': [549, 578, 723], '1988;': [550, 956, 3820], '318:': [551], '1315-1321Crossref': [552], 'Scopus': [554, 570, 583, 673, 702, 728, 763, 779, 848, 909, 960, 1057, 1071, 1122, 1217, 1316, 1422, 2038, 2645, 2752, 2788, 2807, 2827, 2970, 3043, 3081, 3468, 3725, 3824, 3887, 3901, 3915, 3934, 3956, 3980, 4025, 4148, 4206, 4318, 4499, 4538, 4557, 4577, 4613, 4696, 4764, 4835, 4875, 4893, 4913, 5104, 5156, 5248, 5311, 5429, 5473, 5771, 5795, 5832, 5851], '(2345)': [555], '5Ruderman': [558], 'N.B.': [559], 'Williamson': [560], 'J.R.': [561], 'Brownlee': [562], 'FASEB': [564], '6:': [567], '2905-2914Crossref': [568], '(349)': [571], '6Brownlee': [574], 'Annu.': [576], 'Rev.': [577], '1995;': [579, 1113, 1208, 3716, 4016, 4606, 5244, 5764], '46:': [580], '223-234Crossref': [581], '(1163)': [584], 'diabetes,': [588], 'hyperglycemia-driven': [589], 'accumulation': [590], 'AGEs': [592, 609, 1155, 5119], 'has': [593, 628, 798, 860, 1169, 1379, 2926, 3009, 3050, 3766, 4662, 4810, 5062, 5196, 5263, 5802], 'been': [594, 629, 799, 861, 1170, 1380, 2927, 3010, 3051, 3437, 3659, 3667, 3767, 4663, 4811, 5197, 5264, 5575, 5803], 'be': [597, 1163, 1173, 1533, 2763, 3054, 3260, 3678, 4482, 4624, 4666, 4997, 5569, 5596, 5960], 'involved': [598, 1493, 2764, 2852, 3096, 3202, 3478, 3499, 3631, 4625, 5070, 5674], 'pathogenesis': [601], 'diabetic': [603, 640, 1234, 5218], 'vascular': [604, 624, 1235, 5190, 5206, 5219], 'disease.': [605], 'interaction': [607, 792], 'RAGE,': [611, 3674, 4070], 'one': [612, 2204, 3508], 'their': [614, 4790, 5506, 5543], 'receptors,': [616], 'results': [617, 5547, 5573], 'perturbation': [619], 'variety': [622], 'homeostatic': [625], 'functions': [626, 3781, 5916], 'shown': [630, 800, 862, 1381, 2443, 2876, 2928, 3011, 3052, 3317, 3438, 3568, 3676, 4664, 4730, 5198, 5265, 5354, 5804], 'major': [634], 'development': [638, 1029, 5085, 5216, 5970], 'vasculopathy': [641], '(7Schmidt': [642], 'Hasu': [644], 'Popov': [646], 'Zhang': [648, 1092, 1187, 1326, 2980, 3695, 3995, 4216, 4269, 5166, 5231], 'J.H.': [649], 'Chen': [650, 817, 821, 890, 1094, 1189, 1285, 1289, 2939, 2943, 3697, 3997, 4117, 4121, 4175, 4179, 5125, 5129, 5225, 5292], 'Cao': [656, 687, 1090, 1185, 3693, 3993, 5233], 'Kuwabara': [658], 'Costache': [660], 'G.': [661], 'Proc.': [662, 898, 4307, 5300], 'Natl.': [663, 899, 4308, 5301], 'Acad.': [664, 900, 4309, 5302], 'Sci.': [665, 901, 4310, 5303], 'U.': [666, 902, 4311, 5304], 'S.': [667, 903, 1101, 1196, 2778, 2795, 2797, 3453, 3704, 3949, 3974, 4004, 4312, 4528, 4545, 4547, 4684, 4686, 4749, 5305, 5368], '1994;': [669, 1067, 1339, 2993, 3897, 4229, 4282, 4314, 4831, 5179], '91:': [670, 4315], '8807-8811Crossref': [671], '(285)': [674], '8Wautier': [677], 'J.L.': [678], 'Zoukourian': [679], 'Chappey': [681], 'O.': [682, 690, 1085, 1180, 1405, 3026, 3688, 3988, 5224], 'Wautier': [683], 'M.P.': [684, 4296], 'Guillausseau': [685], 'P.J.': [686], 'Hori': [689, 1404, 3025, 3984, 5223], 'Clin.': [696, 5242], 'Invest.': [697, 5243], '1996;': [698, 844, 1312, 2784, 2966, 4144, 4202, 4534, 4871, 5152, 5883], '97:': [699], '238-243Crossref': [700], '(502)': [703], '9Park': [706], 'L.': [707, 830, 1298, 2772, 2776, 2799, 2952, 3455, 4130, 4188, 4522, 4526, 4549, 4688, 4757, 4829, 4861, 5138], 'Raman': [708], 'K.G.': [709], 'Lee': [710], 'K.J.': [711], 'Lu': [712], 'Y.': [713], 'Ferran': [714], 'L.J.J.': [715], 'Chow': [716], 'W.S.': [717], 'Nat.': [722], '1998;': [724, 2748, 3072, 3930, 3976, 4495, 4760, 4909, 5373, 5464], '4:': [725], '1025-1031Crossref': [726], '(1027)': [729], "Alzheimer's": [733, 875, 1239, 5277], 'disease,': [734, 1240], 'deposition': [735], 'β-peptide': [738, 785, 805, 859, 1158, 4074, 5122, 5262], 'containing': [739, 1588, 1636, 1783, 1803, 1976, 2052, 2099, 2269, 2306], 'plaques': [740], 'brain': [743, 924, 5072, 5278], 'correlates': [744], 'progressive': [746], 'neuronal': [747, 787, 855, 3653, 5084], 'dysfunction': [748], 'leading': [749, 868], 'dementia': [751], '(10Yankner': [752], 'B.A.': [753], 'Duffy': [754], 'L.K.': [755], 'Kirschner': [756], 'D.A.': [757, 4306], 'Science.': [758, 2747, 4494, 5846], '1990;': [759], '250:': [760], '279-282Crossref': [761], '(1917)': [764], '11Haass': [767], 'Selkoe': [769], 'D.J.': [770, 5869], 'Cell.': [771, 2801, 4551, 4605, 4690, 5763, 5881], '75:': [773], '1039-1042Abstract': [774], '(742)': [780], 'Extracellular': [783], 'death': [789], 'presumably': [790], 'receptors.': [795], 'Neuronal': [796], 'interact': [802], '(12Yan': [815, 1283, 2937, 4173, 5123], 'X.': [818, 891, 1286, 2940, 4118, 4176, 5126, 5293, 5458], 'Fu': [819, 881, 1287, 2941, 4119, 4177, 5127, 5283], 'Zhu': [823, 879, 1291, 2945, 4123, 4181, 5131, 5281], 'Roher': [825, 885, 1293, 2947, 4125, 4183, 5133, 5287], 'Slattery': [827, 1088, 1183, 1295, 2949, 3691, 3991, 4127, 4185, 5135], 'T.': [828, 1089, 1184, 1296, 2950, 3064, 3692, 3992, 4128, 4186, 4823, 4865, 5136, 5782, 5841, 5879], 'Zhao': [829, 1297, 2951, 3921, 4129, 4187, 4826, 5137], 'Nagashima': [831, 1096, 1191, 1299, 2953, 3699, 3999, 4131, 4189, 5139], 'Morser': [833, 1104, 1199, 1301, 2955, 3707, 4007, 4133, 4191, 5141], 'Migheli': [835, 1303, 2957, 4135, 4193, 5143], 'Nawroth': [837, 1305, 2959, 4137, 4195, 5145], 'P.': [838, 952, 1306, 2960, 3816, 4138, 4196, 5146, 5780, 5877], 'Nature.': [843, 1311, 2783, 2965, 4143, 4201, 4533, 4830, 5151, 5827], '382:': [845, 1313, 2967, 4145, 4203, 5153], '685-691Crossref': [846, 1314, 2968, 4146, 4204, 5154], '(1827)': [849, 1317, 2971, 4149, 4207, 5157], 'trigger': [864, 3013], 'proinflammatory': [866], 'pathway': [867, 1387, 1433, 1451, 3018, 3094, 3137, 3200, 5860, 5958], 'microglial': [872], 'disease': [876, 1236, 5220], '(13Du': [877, 5279], 'S.F.': [884, 5286], 'Tourtellotte': [887, 5289], 'W.W.': [888, 5290], 'Rajavashisth': [889, 5291], 'Godman': [892, 5294], 'G.C.': [893, 5295], '1997;': [905, 1413, 2641, 2803, 2818, 3034, 3464, 3911, 3952, 4553, 4568, 4692, 4886, 5095, 5307, 5420, 5791], '94:': [906, 5308], '5296-5301Crossref': [907, 5309], '(254)': [910, 5312], 'Amphoterin': [913, 1012, 1143, 3729], 'heparin-binding,': [916], 'outgrowth-promoting': [918, 2606, 2679], 'isolated': [920], 'neonatal': [922], 'rat': [923, 1151, 1696, 3247], '(14Rauvala': [925, 1030, 3789], 'Pihlaskari': [927, 945, 966, 1032, 1933, 3791, 3809, 3830], '1987;': [932, 1037, 3796], '262:': [933, 1038, 3797], '16625-16635Abstract': [934, 1039, 3798], '15Rauvala': [941, 3805], 'Merenmies': [943, 990, 1905, 1931, 3743, 3807, 3854], 'Korkolainen': [947, 3811], 'Huhtala': [949, 3813], 'M.L.': [950, 3814], 'Panula': [951, 3815], 'Cell': [954, 1051, 2032, 3818, 3881, 4884], '107:': [957, 3821], '2293-2305Crossref': [958, 3822], '(76)': [961, 3825, 3981], '16Merenmies': [964, 3828], 'Laitinen': [968, 3832], 'Wartiovaara': [970, 3834], 'Rauvala': [972, 998, 1913, 1935, 3751, 3836, 3862], '1991;': [977, 1053, 3841, 3883, 5828, 5847], '266:': [978, 3842], '16722-16729Abstract': [979, 3843], '17Parkkinen': [986, 3850], 'Raulo': [988, 1903, 3741, 3852], 'Nolo': [992, 1907, 3745, 3856], 'Kajander': [994, 1909, 3747, 3858], 'E.O.': [995, 1910, 3748, 3859], 'Baumann': [996, 1911, 3749, 3860], '268:': [1004, 1919, 3757, 3868], '19726-19738Abstract': [1005, 1920, 3758, 3869], 'abundantly': [1014], 'expressed': [1015, 2871, 3225], 'central': [1018, 3420], 'peripheral': [1020], 'nervous': [1021, 1152, 3785, 4060, 5975], 'systems': [1022, 3788, 5758], 'later': [1025], 'phases': [1026, 4799], 'embryonic': [1028], '18Daston': [1046, 3876], 'M.M.': [1047, 1062, 3877, 3892], 'Ratner': [1048, 1063, 3878, 3893], '112:': [1054, 3884], '1229-1239Crossref': [1055, 3885], '(55)': [1058, 3888], '19Daston': [1061, 3891], 'Neurocytol.': [1066, 3896], '23:': [1068, 3898], '323-332Crossref': [1069, 3899], '(22)': [1072, 3902], 'binds': [1076, 4032], 'amphoterin': [1077, 1168, 1891, 2073, 2258, 2288, 2315, 2467, 2573, 2686, 2840, 2895, 3149, 3275, 3322, 3344, 3409, 3555, 4033, 4046, 4384, 4594, 4645, 5321, 5383, 5489, 5502, 5519, 5535, 5652, 5701], 'saturable': [1080], 'dose-dependent': [1082, 4036], 'manner': [1083, 4172, 4360], '(20Hori': [1084, 1179, 3687, 3987], 'J.X.': [1095, 1190, 3698, 3998, 5226], 'Lundh': [1098, 1193, 3701, 4001], 'E.R.': [1099, 1194, 3702, 4002], 'Vijay': [1100, 1195, 3703, 4003], 'Nitecki': [1102, 1197, 3705, 4005], '270:': [1114, 1209, 3717, 4017], '25752-25761Abstract': [1115, 1210, 3718, 4018], '(1030)': [1123, 1218, 3726, 4026], 'anti-RAGE': [1127], 'F(ab′)2': [1128], 'soluble': [1130, 5518], 'ectodomain': [1131], 'blocks': [1134], 'cortical': [1138], 'neurons': [1139, 5253, 5362], 'coexpressed': [1147], 'developing': [1150, 3784, 4059], 'system.': [1153, 4061, 5976], 'Since': [1154, 4700], 'expected': [1161], 'present': [1164], 'under': [1165, 1650, 2339, 5449], 'non-pathophysiological': [1166], 'conditions,': [1167], 'physiological': [1175], 'ligand': [1176], 'Although': [1221], 'previous': [1222], 'studies': [1223, 5594], 'have': [1224, 2905, 3435, 3658, 3666, 3779, 4049, 5510, 5574], 'identified': [1225, 4812], 'as': [1227, 1673, 1769, 1898, 2026, 2289, 2375, 2453, 2479, 2611, 2614, 3309, 3441, 3448, 4354, 4392, 4813, 4844, 5205], 'potential': [1229], 'therapeutic': [1230], 'target': [1231], 'both': [1232, 1468, 3190, 3321, 3343, 3594, 4256, 4634, 4742, 5609, 5650, 5700], 'basic': [1242, 2625], 'biology': [1244], 'well': [1249], 'understood.': [1250], 'either': [1256, 2390, 2419, 2883, 3155, 3273, 3554, 4703, 5118], 'pathophysiologically': [1259], 'relevant': [1260], 'AGE': [1262, 2922, 3326, 3349, 3405, 3561, 4071, 4252, 5703, 5943], 'result': [1269, 2930], 'generation': [1271], '21Yan': [1320, 2974, 4210, 5160], 'Anderson': [1324, 2978, 4214, 4267, 5164], 'G.M.': [1325, 2979, 4215, 4268, 4906, 5165, 5845], '269:': [1340, 2994, 4230, 4283, 5180], '9889-9897Abstract': [1341, 2995, 4231, 4284, 5181], 'It': [1348, 1426, 4503, 4995, 5379], 'still': [1350, 4243, 5524, 5907], 'clear': [1352], 'whether': [1353, 1430, 2846, 3088, 3209, 4245, 4351, 5001], 'tethering': [1359], 'these': [1360, 2340, 3174, 3492, 4508], 'oxidizing': [1361], 'agents': [1362], 'surface': [1366, 4326], 'signaling.': [1372, 2855, 4332, 4628, 5743], 'induction': [1375, 2932, 3004], 'activate': [1383, 4165, 4734], 'Ras-MAP': [1385, 3092, 3198, 5735], 'may': [1389, 2761, 5548, 5959], 'eventually': [1390], 'lead': [1391, 5713], 'nuclear': [1394, 3222, 3638, 5581], 'translocation': [1395, 3639], '(22Lander': [1398, 3019], 'H.M.': [1399, 3020, 3068], 'Tauras': [1400, 3021], 'J.M.': [1401, 3022, 4294], 'Ogiste': [1402, 3023], 'J.S.': [1403, 3024], 'Moss': [1406, 3027], 'R.A.': [1407, 3028, 4304], '272:': [1414, 3035, 5421], '17810-17814Abstract': [1415, 3036], '(683)': [1423, 3044], 'known': [1429, 2705, 3134], 'this': [1431, 1455, 3091, 4344, 4965, 5316, 5446, 5616], 'responsible': [1435, 3651, 5603], 'proximal': [1445], 'components': [1446, 3089, 3131, 4514], 'study,': [1456, 5507, 5617], 'demonstrate': [1458, 2581, 3126, 5319], 'required': [1466, 3217, 5597, 5698, 5901], 'We': [1477, 3085, 3665, 5977], 'also': [1478, 2762, 3127, 3216, 3395, 3411, 3436, 3498, 4512, 5069, 5082, 5323, 5856], 'Rho': [1485, 2699, 2716, 2848, 3196, 3423, 3493, 3627, 4473, 4620, 4650, 4661, 5670, 5754], 'family': [1486, 2700, 2849, 3424, 3494, 3628, 4474, 4621, 4806, 4840, 5671], 'small': [1487, 2702, 3425, 3495, 4475], 'GTPases': [1488, 2703, 2850, 3426, 3496, 4476, 5672], 'were': [1504, 1581, 1602, 1630, 1699, 1723, 1778, 1789, 1808, 1855, 1876, 1894, 2023, 2046, 2067, 2086, 2127, 2154, 2190, 2244, 2263, 2284, 2337, 2409, 2455, 2593, 2870, 3146, 3268, 3307, 3329, 3518], 'unable': [1505], 'find': [1507], 'evidence': [1508, 2757, 5061, 5747], 'involvement': [1511, 5028], 'suggesting': [1522, 5433], 'mechanism': [1526, 4336, 5602], 'consisting': [1527], 'parallel': [1530, 2591], 'can': [1532, 4158, 4733], 'Human': [1541], 'cDNA': [1543, 1614, 1649, 1768], 'was': [1544, 1561, 1617, 1671, 1686, 1740, 1759, 1846, 1953, 1999, 2012, 2167, 2209, 2312, 2325, 2349, 2429, 2506, 2586, 3252, 3292, 3358, 3376, 3544, 3577, 3589, 4348, 4728, 5353, 5448, 5453, 5503], 'generous': [1546, 1604, 1619], 'gift': [1547, 1605, 1620], 'Dr.': [1549, 1607, 1622, 5979, 5991, 6011], 'David': [1550, 5980], 'Stern,': [1551], 'Columbia': [1552], 'University,': [1553], 'New': [1554], 'York.': [1555], 'mutant': [1559, 1580, 2397, 2477, 2543, 3106, 3234, 4405], '(Δ367–404)': [1560], 'generated': [1562], 'polymerase': [1564], 'chain': [1565], 'reaction': [1566], 'using': [1567, 1764, 2354, 4945, 5656], 'following': [1569, 5075], 'primers:': [1570], '5′-ATAGTCGACATGGCAGCCGG-3′': [1571], '5′-ATAGTCGACTTACCGCCTTTGCCA-3′.': [1573], 'Full-length': [1574], 'subcloned': [1582, 1631], 'into': [1583, 1632, 3520, 5016], 'pcDNA3': [1584], 'vector': [1586, 1635, 2551], '(Invitrogen)': [1587], 'neomycin': [1590], 'selection': [1591], 'cassette.': [1592], 'full-length': [1594, 2392, 2450, 2558, 3227, 3340, 3525, 4371], 'cDNAs': [1595, 1629], 'C3': [1597, 2868, 2901, 3505, 4652, 6002], 'transferase,': [1598], 'N17Rac,': [1599, 3514], 'N17Cdc42': [1601, 2886], 'Alan': [1608, 5992], 'Hall,': [1609], 'MRC,': [1610], 'London,': [1611], 'UK.': [1612], 'N17H-Ras': [1616], 'Johan': [1623, 6012], 'Peränen,': [1624], 'University': [1625], 'Helsinki.': [1627], 'pRK5': [1633], 'Myc': [1638], 'epitope': [1639], 'tag.': [1640], 'cis-reporter': [1642], 'plasmid': [1643, 1845], 'pNFKB-Luc': [1644], '(Stratagene)': [1645, 2357], 'contained': [1646], 'luciferase': [1648, 2347, 3302, 3535], 'regular': [1652, 1883, 2318], 'TATA': [1653], 'box': [1654], 'enhancer': [1657], 'element': [1658], 'five': [1660, 2212], 'NF-κB-binding': [1661, 5411], 'sites.': [1662], 'pFC-MEKK': [1663], '(the': [1664], 'catalytic': [1665], 'MEKK,': [1668], '360–672;': [1669], 'Stratagene)': [1670], 'positive': [1675], 'control': [1676, 2223, 3311, 3363], 'assays.': [1680], 'authenticity': [1682], 'all': [1684], 'constructs': [1685, 4632], 'confirmed': [1687], 'sequencing.': [1689], 'N18': [1690, 1721, 2044, 2385, 4374, 4409, 4445, 4587], 'mouse': [1691], 'C6': [1695, 1787, 2261, 3246, 3521], 'glioma': [1697, 3248], 'cultured': [1700, 1779], "Dulbecco's": [1702, 2095, 2302], 'modified': [1703, 2096, 2303], "Eagle's": [1704, 2097, 2304], 'medium': [1705, 1744, 1782, 1802, 1879, 2098, 2305], 'supplemented': [1706], '100': [1708, 1784], 'units/ml': [1709], 'penicillin': [1710], 'G': [1711], '0.1': [1713, 1977], 'mg/ml': [1714, 1826, 2101, 2308], 'streptomycin': [1715], '10%': [1717], 'fetal': [1718], 'calf': [1719], 'serum.': [1720], 'Tfx-50TM': [1726], 'reagent': [1727], '(Promega)': [1728], 'according': [1729], "manufacturer's": [1732], 'instructions.': [1733], 'G418': [1734], '(600': [1735], 'μg/ml;': [1736, 3557, 3563], 'Life': [1737], 'Technologies,': [1738], 'Inc.)': [1739], 'added': [1741, 1809, 2250, 2326], '48': [1745], 'h': [1746, 2107, 2138, 2344, 2352], 'after': [1747, 2327, 2345, 3549], 'select': [1750], 'stably': [1752], 'clones.': [1754], 'verified': [1760], 'Northern': [1762], 'blotting': [1763], '1.2-kilobase': [1766], 'probe.': [1771], 'For': [1772], 'further': [1773, 2370, 4386, 5014, 5042], 'experiments': [1774, 2592, 5724], 'stable': [1776, 2384], 'transfectants': [1777], 'μg/ml': [1785, 1978, 1981, 1984, 2423, 2466, 2498], 'G418.': [1786], 'electroporation.': [1792], 'Briefly,': [1793], '7.5': [1794], '×': [1795, 2297], '106': [1796, 2298], 'culture': [1801, 1885, 2320], '5': [1804, 1820, 1849, 5687], 'mm': [1805, 1990, 1994, 2054, 2271], 'BES': [1806], '(Sigma)': [1807, 2243], 'electroporation': [1812], 'cuvette': [1813], '(0.4-cm': [1814], 'electrode': [1815], 'gap;': [1816], 'Bio-Rad)': [1817], 'together': [1818, 3237, 3262, 3523], 'μl': [1821], 'carrier': [1823], 'DNA': [1824], '(10': [1825], 'herring': [1827], 'sperm': [1828], 'DNA;': [1829], 'Roche': [1830], 'Molecular': [1831], 'Biochemicals)': [1832], '10': [1834, 1972, 2057, 2100, 2123, 2274, 2307, 2420, 2465, 2565], 'μg': [1835], 'construct': [1837, 3244], 'DNA.': [1838], '1:1:2': [1839], 'ratio': [1840], 'RAGE:dominant': [1842], 'mutant:cis-reporter': [1844], 'used.': [1847], 'After': [1848, 1867, 2116], 'min': [1850, 2058, 2254, 2275], 'ice': [1852], 'electroporated': [1856], 'Gene-Pulser': [1859], '(Bio-Rad)': [1860], '340': [1862], 'V': [1863], '500': [1865], 'millifarads.': [1866], '10-min': [1869], 'incubation': [1870, 2049, 2266], '40': [1872], '°C': [1873, 1970, 2081], 'washed': [1877], 'plated': [1881, 2087, 2313, 2598], 'plates': [1886, 2283, 2316, 2321], '(Corning': [1887], 'Glass).': [1888], 'Baculovirus-derived': [1889], 'recombinant': [1890, 2072, 2287, 2425], 'HB-GAM': [1893, 2075, 2602, 2653], 'prepared': [1895, 1954], 'purified': [1897], 'described': [1899, 2027, 2290], 'previously': [1900], '(17Parkkinen': [1901, 3739], '23Raulo': [1927], 'Julkunen': [1929], 'I.': [1930, 3457], '11408-11416Abstract': [1942], 'AGE-modified': [1949, 3281], 'preincubation': [1956], 'BSA': [1958, 2131, 3282], '(1': [1959], 'mm;': [1960], 'fraction': [1961], 'V,': [1962], 'Sigma)': [1963], '1': [1965, 1989, 1993, 2083, 2137, 2469, 2487, 2512, 2576, 2672], 'm': [1966], 'glucose': [1967, 1998], '37': [1969, 2080], 'weeks': [1973], 'PBS': [1975, 2004, 2051, 2133, 2268], 'pepstatin,': [1979], '0.5': [1980, 2053, 2270], 'leupeptin,': [1982], '2': [1983, 2333], 'aprotinin,': [1985], '1.5': [1986], 'mmphenylmethylsulfonyl': [1987], 'fluoride,': [1988], 'EDTA,': [1991], 'NaN3.': [1995], 'unincorporated': [1997], 'removed': [2000], 'dialysis': [2002], 'against': [2003], '(24': [2005], 'h,': [2006], 'twice).': [2007], 'concentration': [2009, 4452, 4779], 'AGE-BSA': [2011, 2324], 'determined': [2013, 2350, 3087], 'method': [2016], 'Bradford': [2018], '(Bio-Rad).': [2019], 'Neurite': [2020], 'assays': [2022], 'performed': [2024, 2594], 'essentially': [2025], 'before': [2028, 2255], '(24Rauvala': [2029], '1984;': [2034], '98:': [2035], '1010-1016Crossref': [2036], '(36)': [2039], 'Subconfluent,': [2042], 'serum-starved': [2043, 2410, 3269], 'detached': [2047, 2264], 'EDTA': [2055, 2272], 'followed': [2059, 2276], 'vigorous': [2061, 2278], 'pipeting.': [2062, 2279], 'Nunc': [2063], 'Lab-Tek': [2064], 'chamber': [2065], 'slides': [2066, 2416, 2462, 2500], 'coated': [2068, 2089, 2285, 2417, 2463], 'incubating': [2070], 'solution': [2076, 3284], '(10–20': [2077], 'μg/ml)': [2078, 3278], 'h.': [2084, 2334], 'Cells': [2085, 3267], 'wells': [2090], 'grown': [2092, 2412, 2495, 2651, 2838, 3147, 4448, 4589], 'serum-free': [2094, 2301], '24': [2106], 'fixed': [2109], '4%': [2111], 'paraformaldehyde': [2112], '20': [2114, 2422, 2497], 'min.': [2115], 'permeabilization': [2117], '0.2%': [2119], 'Triton': [2120], 'X-100': [2121], 'min,': [2124], '2%': [2130], 'incubated': [2135], 'room': [2140], 'temperature': [2141], 'anti-Myc': [2143], 'tag': [2144], 'antibodies': [2145, 2153, 2161], '(1:500;': [2146], 'clone': [2147], '9E10,': [2148], 'Upstate': [2149], 'Biotechnology).': [2150], 'primary': [2152], 'detected': [2155, 2168], 'fluorescein': [2157], 'isothiocyanate-labeled': [2158], 'goat': [2159], 'anti-mouse': [2160], '(Jackson': [2162], 'ImmunoResearch': [2163], 'Laboratories,': [2164], 'Inc.).': [2165], 'F-actin': [2166], 'simultaneously': [2169], 'TRITC-labeled': [2171], 'phalloidin': [2172], '(Sigma).': [2173], 'Conventional': [2174], 'fluorescence': [2175, 2182], '(Olympus': [2176], 'Provis': [2177], '70)': [2178], 'confocal': [2180], 'laser': [2181], '(Zeiss': [2183], 'LSM': [2184], '410': [2185], 'Invert': [2186], 'Laser': [2187], 'Scan)': [2188], 'microscopes': [2189], 'analyze': [2193], 'results.': [2195], 'proportion': [2197, 2502, 3538], 'neurite-bearing': [2199, 2667], '(processes': [2201], 'longer': [2202], 'than': [2203, 3361, 3380, 4460, 4676, 5343, 5497], 'diameter': [2205], 'cell)': [2208], 'counted': [2210], 'random': [2213], 'fields': [2214], 'three': [2216, 5921], 'independent': [2217, 5710], 'experiments.': [2218], 'Statistically': [2219], 'significant': [2220, 2907, 3178, 3617, 4160, 5525], 'differences': [2221, 2437, 5541], 'between': [2222, 2438, 5733, 5751], 'experimental': [2225], 'conditions': [2226, 2341, 5080], "(Student's": [2227], 't': [2228], 'test)': [2229], 'indicated': [2231, 2247], 'asterisks': [2233], 'bar': [2236], 'graphs.': [2237], 'PD98059,': [2238, 3165], 'wortmannin': [2239], '(Calbiochem),': [2240], 'N-acetyl-l-cysteine': [2242], 'concentrations': [2248, 4592], '30': [2253], 'plating': [2256], 'matrix.': [2259], 'Serum-starved': [2260], '60-mm': [2280], 'non-tissue': [2281], 'culture-treated': [2282], 'above.': [2291], 'Equal': [2292], 'amount': [2293], '(∼2': [2296], 'cells)': [2299], 'which': [2323, 2346, 4977, 5211], 'letting': [2328], 'attach': [2331], 'stimulated': [2338, 3271, 3541], '20–24': [2343], 'activity': [2348, 3536, 3576], '(48': [2351], 'post-transfection)': [2353], 'standard': [2355], 'reagents': [2356], 'measured': [2359, 3545], 'luminometer': [2362], '(Bio-Orbit,': [2363], '1254': [2364], 'Luminova).': [2365], 'order': [2367], 'study': [2369, 2435, 4345, 5317, 5544], 'amphoterin,': [2381, 2612, 4454, 4781], 'produced': [2383], 'lines': [2388], 'expressing': [2389, 2448, 2473, 2557], 'lacking': [2398], '(amino': [2402], 'acids': [2403, 2627], '367–404)': [2404], 'overnight': [2413, 3272, 3551], 'glass': [2415], 'amphoterin.': [2426, 4398, 5513, 5927], 'Filamentous': [2427], 'actin': [2428, 2712, 3432, 4487, 4858], 'then': [2430, 3293, 5712], 'stained': [2431], 'TRITC-phalloidin': [2433], 'morphological': [2436, 2657, 4471], 'lines.': [2441], 'As': [2442, 2875, 3316, 3472], 'Fig.': [2445, 2878, 3570, 5686], '1,': [2446, 2528], '(designated': [2452, 2478], 'N18/RAGE)': [2454], 'capable': [2456, 2507, 3330, 3412, 3679, 5005, 5324], 'extending': [2458, 2509], 'numerous': [2459, 4457], '(Fig.': [2468, 2486, 2511, 2527, 2575, 2671, 3119, 3184], 'A),': [2470], 'whereas': [2471, 2897, 3608, 4647, 5508], 'N18/RAGEΔcyto;': [2480], 'Fig.1': [2481], 'B)': [2482], 'mock-transfected': [2484, 3305, 3384, 4419], 'C)': [2488], 'did': [2489, 2903, 3113], 'display': [2491], 'such': [2492, 2613, 3447, 5204, 5386, 5749], 'morphology.': [2493], 'When': [2494, 4443], 'N18/RAGE': [2504, 2649, 2836, 2873, 2888, 3111, 3144, 4774], 'D).': [2513], 'N18/RAGEΔcyto': [2516, 2662], 'N18/mock': [2518, 2664], 'grew': [2520], 'few': [2521, 3645], 'processes': [2522], 'hardly': [2524], 'any': [2525], 'E': [2529], 'andF,': [2530], 'respectively).': [2531], 'comparison': [2533, 2660], '(2.7': [2546], '±': [2547, 2553, 2561, 3346, 3351, 3597, 3602], '2.1%)': [2548], 'empty': [2550], '(3.1': [2552], '1.7%),': [2554], '(20.0': [2560], '5.6%)': [2562], 'had': [2563, 3176, 3615, 4654, 5520], 'nearly': [2564], 'times': [2566], 'higher': [2567, 3360, 3379], 'capacity': [2568], 'growing': [2570], 'matrix': [2574, 2654, 3150, 3276, 4385], 'G,': [2577, 2673], 'black': [2578, 3558], 'bars).': [2579, 2675], 'To': [2580, 3125, 3207], 'specific': [2587, 2684, 3444], 'substrates,': [2590, 4043], 'HB-GAM-coated': [2600], 'slides.': [2601], 'another': [2604], 'similar': [2609, 4054, 4991], 'characteristics': [2610], 'high': [2615, 3255, 3264, 3735], 'affinity': [2616], 'binding': [2617, 2914, 5007, 5487], 'heparin': [2619], 'sequence': [2622, 4927], 'rich': [2623], 'amino': [2626], '(for': [2628], 'review': [2630], 'see': [2631, 3486, 5000], 'Ref.': [2632, 2744, 4491, 5088], '25Rauvala': [2633], 'Peng': [2635], 'H.B.': [2636], 'Prog.': [2637], 'Neurobiol.': [2638], '(New': [2639], 'York).': [2640], '52:': [2642], '127-144Crossref': [2643], '(93)': [2646], 'displayed': [2655], 'no': [2656, 3616, 4655], 'difference': [2658], '(<5%': [2666], 'each)': [2670], 'gray': [2674, 3564], 'Thus,': [2676, 4333, 5539], 'effect': [2680, 2908, 3179, 4063, 4851, 5389, 5526], 'requires': [2688, 4362], 'presence': [2690, 3153, 5407], 'receptor.': [2697, 4368], 'various': [2708], 'aspects': [2709], 'cytoskeleton.': [2713], 'fibroblasts,': [2715], 'regulates': [2717, 2727, 2737], 'formation': [2719, 2732, 2739, 5964], 'fibers': [2722], 'focal': [2724], 'complexes,': [2725], 'membrane': [2728, 4919], 'ruffling': [2729], 'lamellipodia,': [2734], '(reviewed': [2742, 4489, 5086], '26Hall': [2745, 4492], '279:': [2749, 4496], '509-514Crossref': [2750, 4497], '(5230)': [2753, 4500], 'Recent': [2756], 'suggests': [2758, 4465, 5688], 'they': [2760, 3434, 4718, 4948], 'neuritogenesis': [2766], 'growth': [2768, 5348], 'cone': [2769], '(27Luo': [2771, 4521], 'Hensch': [2773, 4523], 'T.K.': [2774, 4524], 'Ackerman': [2775, 4525], 'Barbel': [2777, 4527], 'Jan': [2779, 2781, 4529, 4531], 'L.Y.': [2780, 4530], 'Y.N.': [2782, 4532], '379:': [2785, 4535], '837-840Crossref': [2786, 4536], '(397)': [2789, 4539], '28Kozma': [2792, 4542], 'Sarner': [2794, 4544, 4683], 'Ahmed': [2796, 4546, 4685, 4748], 'Lim': [2798, 4548, 4687, 4756, 4828], 'Mol.': [2800, 4550, 4689, 5880], '17:': [2804, 4554, 4693, 4761, 4910], '1201-1211Crossref': [2805, 4555, 4694], '(535)': [2808, 4558, 4697], '29Threadgill': [2811, 4561], 'Bobb': [2813, 4563], 'Ghosh': [2815, 4565], 'Neuron.': [2817, 4567], '19:': [2819, 4569], '625-634Abstract': [2820, 4570], '(432)': [2828, 4578], 'Considering': [2831], 'filopodial': [2833, 4599, 4771], 'morphology': [2834, 4600, 4772], 'matrix,': [2841, 2896, 4646], 'wanted': [2843, 3484], 'determine': [2845, 3208, 4350], 'Dominant': [2856], 'mutants': [2858, 3513, 4947], '(T17N)': [2859, 3107], 'Rho-inhibitory': [2866], 'transferase': [2869, 2902, 3506, 4653, 6003], 'cells.': [2874, 3249, 3364, 3385, 4420], '2,': [2879, 3120], 'transient': [2880, 3256], 'overexpression': [2881], 'N17Rac': [2884], 'completely': [2890, 4638, 5727], 'abolished': [2891], 'outgrowth.': [2912, 3100, 3206, 4961, 5026], 'Recently': [3002], 'Ras-dependent': [3015], 'recruited': [3055], '(30Deora': [3061], 'A.A.': [3062], 'Win': [3063], 'Vanhaesebroeck': [3065], 'B.': [3066, 3572, 3943, 3970], 'Lander': [3067], '273:': [3073, 5465], '29923-29928Abstract': [3074], '(167)': [3082], 'therefore': [3086], 'Expression': [3101], 'Ha-Ras': [3109], 'affect': [3115], 'D,': [3121], 'H,': [3122], 'I).': [3124], 'dispensable': [3139], 'outgrowth,': [3143, 3482, 4714], 'antioxidant': [3157], 'N-acetyl-l-cysteine,': [3158], 'MEK': [3160], '(MAP': [3161], 'kinase)': [3163], 'inhibitor': [3164, 3170], 'PI': [3168], 'wortmannin.': [3171], 'None': [3172], 'compounds': [3175], '3).': [3185], 'indicate': [3188, 3621], 'factor-κB,': [3223], 'NF-κB-responsive': [3240, 3529], 'reporter': [3241, 3530], '(luciferase)': [3243], 'This': [3250, 3386, 4421, 4464, 4657], 'system': [3251, 5191], 'because': [3254, 5937], 'levels': [3258], 'could': [3259, 5384], 'obtained': [3261, 5576], 'efficiency': [3265], 'transfection.': [3266], '(20': [3277, 3556], '(500': [3285, 3562], 'μg/ml).': [3286], 'enhancement': [3288], 'quantitated': [3294], 'lysates': [3298, 3548], 'measuring': [3300, 5579, 5587], 'activity.': [3303, 3315, 4941], 'Non-stimulated': [3304], 'basal': [3313], 'transcriptional': [3314, 3575], 'Fig.4': [3319], 'A,': [3320], '(black': [3323], 'bars)': [3324, 3328, 3559, 3565], '(gray': [3327], 'activating': [3332, 3414, 5326], 'With': [3342], '(337': [3345], '86%)': [3347], '(377': [3350], '104%)': [3352], 'significantly': [3359, 3593], 'level': [3366, 4417], 'RAGEΔcyto': [3375], 'remarkably': [3378], 'similarly': [3382, 3540], 'treated': [3383], 'indicates': [3387], 'needed': [3396], 'NF-κB,': [3400, 5051], 'addition': [3403, 3417, 3489, 3770], 'β,': [3408], 'regulation': [3429, 5440], 'cytoskeleton,': [3433], 'function': [3440, 3774], 'regulators': [3442, 4484], 'factors': [3446], '(31Perona': [3450], 'Montaner': [3452], 'Saniger': [3454], 'Sanchez-Perez': [3456], 'Bravo': [3458], 'Lacal': [3460], 'J.C.': [3461], 'Genes': [3462], 'Dev.': [3463], '11:': [3465], '463-475Crossref': [3466], '(537)': [3469], 'clearly': [3477], 'whether,': [3487], 'Ras,': [3491], 'N17Cdc42,': [3515], 'N17Ras': [3517], 'construct.': [3532], 'relative': [3534], 'RAGE-transfected': [3542, 4444, 4586], 'stimulation': [3552], '4': [3571], 'only': [3578, 5665], 'co-transfected': [3582], 'N17Ras.': [3584], 'able': [3590, 4709], 'amphoterin-induced': [3595, 4470, 5335, 5479, 5951], '(67': [3596], '4.3%)': [3598], 'AGE-induced': [3600], '(77': [3601], '7.5%)': [3603], 'transcription,': [3607], 'inhibition': [3609, 4648, 4701], 'Rho,': [3611], 'Rac,': [3612], 'effect.': [3618, 4656], 'members': [3629, 4622, 4841], 'apparent': [3637, 4506], 'During': [3642], 'last': [3644], 'years,': [3646], 'signal': [3648], 'transduction': [3649], 'differentiation': [3654], 'subject': [3661], 'intense': [3663], 'research.': [3664], 'interested': [3668], 'particular': [3671], 'receptor,': [3672], 'namely': [3673], 'recently': [3675, 4729], 'mediating': [3681, 4848], 'substrates': [3686], 'mobility': [3736], 'group': [3737], 'shown,': [3768], 'its': [3772, 5920], 'putative': [3773], 'nucleus,': [3777], 'hematopoietic': [3787], '32Nair': [3905], 'S.M.': [3906, 3920], 'Jungalwala': [3907, 3927], 'F.B.': [3908, 3928], 'Neurochem.': [3910], '68:': [3912], '1286-1297Crossref': [3913], '(35)': [3916], '33Nair': [3919], 'Z.': [3922], 'Chou': [3923], 'D.K.': [3924], 'Tobet': [3925], 'S.A.': [3926], 'Neuroscience.': [3929, 3975], '85:': [3931], '759-771Crossref': [3932], '(23)': [3935], '34Passalacqua': [3938], 'Zicca': [3940], 'Sparatore': [3942, 3969], 'Patrone': [3944, 3962], 'Melloni': [3946, 3971], 'Pontremoli': [3948, 3973], 'FEBS': [3950], 'Lett.': [3951], '400:': [3953], '275-279Crossref': [3954], '(50)': [3957], '35Passalacqua': [3960], 'Picotti': [3964], 'G.B.': [3965], 'Del': [3966], 'Rio': [3967], '82:': [3977], '1021-1028Crossref': [3978], 'et': [3985, 4899], 'al.': [3986, 4900], 'showed': [4029], 'manner,': [4037], 'spatially': [4051], 'temporally': [4053], 'pattern': [4056], 'ligands': [4068], '12Yan': [4115], 'Scholar),': [4151, 4321], 'dramatically': [4155], 'different.': [4156], 'generate': [4159], 'RAGE-dependent': [4171], 'Despite': [4238], 'intensive': [4239], 'investigation': [4240], 'it': [4241, 4715, 4727, 4782, 5331, 5567], 'unknown': [4244], 'bringing': [4251], 'sources': [4257], 'reactive': [4259], 'oxygen': [4260], 'species': [4261], 'themselves': [4262], '(21Yan': [4263], '36Hensley': [4291], 'Carney': [4293], 'Mattson': [4295], 'Aksenova': [4297], 'Harris': [4299], 'Wu': [4301], 'J.F.': [4302, 5228], 'Floyd': [4303], 'Butterfield': [4305], '3270-3274Crossref': [4316], '(1093)': [4319], 'close': [4322], 'presents': [4339], 'several': [4340], 'interesting': [4341, 4998, 5891], 'questions.': [4342], 'our': [4346, 5515, 5546, 5572, 5723], 'aim': [4347], 'acts': [4353], 'Transfection': [4369], 'sufficient': [4378, 4929], 'confirming': [4387], 'when': [4400, 5445, 5531], 'reduced': [4414], 'implies': [4422], 'perhaps': [4434, 4796], 'complex': [4437, 5812], 'necessary': [4438, 4958, 4979, 5861], 'initiate': [4440, 4981], 'extension.': [4442, 4983], 'lower': [4451, 4591, 4778], 'rather': [4459, 4675, 5496], 'observed.': [4463], 'dose': [4467], 'dependence': [4468], 'changes.': [4472], 'now': [4478], 'widely': [4479], 'accepted': [4480], 'key': [4483], 'cytoskeleton': [4488, 4794, 4859], 'becoming': [4505], 'critical': [4513], 'cytoskeletally': [4517], 'driven': [4518], 'striking': [4582], 'resemblance': [4583], 'typical': [4597], 'Cdc42-induced': [4598], '(37Nobes': [4601, 5759], 'C.D.': [4602, 5760], 'Hall': [4603, 4754, 4866, 4903, 5761, 5819, 5993], '81:': [4607, 5765], '53-62Abstract': [4608, 5766], '(3747)': [4614, 5772], 'might': [4623, 4967, 5212, 5895], 'Indeed,': [4629], 'reasonable': [4659], 'since': [4660], 'mediator': [4668], 'lysophosphatidic': [4671], 'acid-induced': [4672], 'retraction': [4674], '(28Kozma': [4681], 'alone': [4707], 'block': [4711], 'seems': [4716], 'lie': [4719, 5549], 'same': [4722], 'pathway.': [4724], 'fact': [4726], 'PAK,': [4737], 'downstream': [4739, 4850], 'effector': [4740], '(38Obermeier': [4746], 'Manser': [4750, 4862], 'Yen': [4752], 'S.C.': [4753], 'EMBO': [4758, 4907, 5789], '4328-4339Crossref': [4762], '(174)': [4765], 'considering': [4769], 'possible': [4784, 5381, 5435], 'mediate': [4789], 'effects': [4791], 'independently,': [4795], 'different': [4798, 5558], 'neuritogenesis.': [4801], '(PAK)': [4805], 'serine/threonine': [4808], 'kinases': [4809], 'targets': [4814], 'active': [4816], '(39Manser': [4820], 'Leung': [4822, 4864], 'Salihuddin': [4824], 'Z.S.': [4827], '367:': [4832], '40-46Crossref': [4833], '(1305)': [4836], 'PAK': [4839, 5030], 'considered': [4843], 'main': [4845], 'candidate': [4846], 'effectors': [4847, 5033], '(40Lim': [4860], 'Eur.': [4868], 'Biochem.': [4870], '242:': [4872], '171-185Crossref': [4873], '(273)': [4876], '41Sells': [4879], 'M.A.': [4880], 'Chernoff': [4881], 'Trends': [4883, 5093], '7:': [4887], '162-167Abstract': [4888], '(265)': [4894], 'Recently,': [4897, 5060, 5346], 'Daniels': [4898], '(42Daniels': [4901], 'R.H.': [4902], 'P.S.': [4904], 'Bokoch': [4905, 5844], '754-764Crossref': [4911], '(257)': [4914], 'reported': [4917], 'targeting': [4920], 'PAK1': [4922, 4939, 4956], 'via': [4923], 'C-terminal': [4925], 'isoprenylation': [4926], 'PC12': [4935], 'independently': [4937], 'Quite': [4942], 'interestingly,': [4943], 'truncated': [4946], 'found': [4949, 5663], 'acidic': [4952, 4993], 'glutamate/aspartate-rich': [4953], 'region': [4954, 4966, 5401], 'They': [4962], 'speculated': [4963], 'act': [4968], 'recruit': [4970], 'plasma': [4975], 'membrane,': [4976], 'contains': [4989], 'highly': [4992], 'region.': [4994], 'will': [4996, 5012, 5595], 'identification': [5002], 'give': [5013], 'insight': [5015], 'and/or': [5036, 5971], 'awaits': [5041], 'investigation.': [5043], 'One': [5044], 'best': [5047], 'characterized': [5048], 'factors,': [5050], 'classically': [5053], 'linked': [5054], 'inflammation': [5056], 'responses.': [5059], 'begun': [5063], 'function,': [5073], 'particularly': [5074], 'neurodegenerative': [5079], "43O'Neill": [5089], 'L.A.': [5090], 'Kaltschmidt': [5091], 'Neurosci.': [5094, 5372], '20:': [5096], '252-258Abstract': [5097], '(921)': [5105], 'Activation': [5108], 'hallmark': [5113], 'genes': [5203], 'molecule-1': [5209], '(VCAM-1),': [5210], 'contribute': [5213, 5340, 5356], '(44Schmidt': [5221], 'Li': [5227], 'Crandall': [5229], '96:': [5245], '1395-1403Crossref': [5246], '(824)': [5249], 'response': [5259, 5275], 'macrophage-colony-stimulating': [5270], 'strengthening': [5272], 'inflammatory': [5274, 5344], 'likely': [5333], 'changes': [5336], 'processes.': [5345], 'nerve': [5347], 'factor-dependent': [5349], 'survival': [5359, 5388], 'sympathetic': [5361], '(45Maggirwar': [5363], 'S.B.': [5364], 'Sarmiere': [5365], 'P.D.': [5366], 'Dewhurst': [5367], 'Freeman': [5369], 'R.S.': [5370], '18:': [5374], '10356-10365Crossref': [5375], 'Interestingly,': [5395], 'analysis': [5397], 'promoter': [5400], 'revealed': [5405], 'functional': [5410, 5635], 'sites': [5412], '(46Li': [5413], '16498-16506Abstract': [5422], '(453)': [5430], 'autoregulatory': [5436], 'loop': [5437], 'expression.': [5443], 'manuscript': [5447], 'preparation': [5450], 'finding': [5452], 'published': [5454], '(47Li': [5455], 'Qu': [5457], '30870-30878Abstract': [5466], '(70)': [5474], 'showing': [5477], 'increase': [5480], 'mediated': [5485], 'Sp1': [5494], 'Soluble': [5501], 'matrix-bound': [5512, 5534], 'assay': [5517], 'weaker': [5522], 'compared': [5532], '(data': [5536], 'shown).': [5538], 'somewhere': [5550], 'else,': [5551], 'example': [5553], 'use': [5556], 'types': [5560], 'length': [5563], 'stimulation.': [5565], 'Also': [5566], 'should': [5568], 'noted': [5570], 'localization': [5582], 'Further': [5593], 'establish': [5599], 'molecular': [5601], 'vivo.': [5614], 'dependent': [5627], 'Ras.': [5636, 6020], 'Deletion': [5637], 'AGE.': [5654], 'approach': [5660], 'again,': [5661], 'schematic': [5682], 'model': [5683], 'presented': [5684], 'similar,': [5691], 'yet': [5692], 'unknown,': [5693], 'membrane-proximal': [5694], 'component': [5696], 'signaling,': [5706], 'parallel,': [5709], 'cytoskeletal': [5720], 'reorganization.': [5721], 'do': [5725], 'exclude': [5728], 'possibility': [5730, 5892], 'cross-talk': [5732, 5750], 'Cdc42-Rac': [5739], 'There': [5744], 'substantial': [5746], '48Frost': [5775], 'J.A.': [5776], 'Steen': [5777], 'Shapiro': [5779], 'Lewis': [5781], 'Ahn': [5783], 'P.E.': [5786], 'Cobb': [5787], 'M.H.': [5788], '16:': [5792, 5884], '6426-6438Crossref': [5793], '(362)': [5796], 'addition,': [5800], 'participate': [5806], 'NADPH': [5811], 'phagocytes': [5814], '(49Abo': [5815], 'Pick': [5817], 'Totty': [5821], 'Teahan': [5823], 'C.G.': [5824], 'Segal': [5825], 'A.W.': [5826], '353:': [5829], '668-670Crossref': [5830], '(767)': [5833], '50Knaus': [5836], 'U.G.': [5837], 'Heyworth': [5838], 'P.G.': [5839], 'Evans': [5840], 'Curnutte': [5842], 'J.T.': [5843], '254:': [5848], '1512-1515Crossref': [5849], '(545)': [5852], 'redox-dependent': [5859], 'nonphagocytic': [5866], '(51Sulciner': [5868], 'Irani': [5870], 'Yu': [5872], 'Z.X.': [5873], 'Ferrans': [5874], 'V.J.': [5875], 'Goldschmidt-Clermont': [5876], 'Finkel': [5878], '7115-7121Crossref': [5885], 'Thus': [5889], 'intracellular': [5897], 'production': [5898], 'radicals': [5900], 'remains.': [5908], 'An': [5909], 'intriguing': [5910], 'scenario': [5911], 'appearing': [5913], 'ligands:': [5922], 'AGE,': [5923], 'Detailed': [5928], 'understanding': [5929], 'important': [5936, 5961], 'pathophysiological': [5940], 'relevance': [5941], 'β-peptide.': [5946], 'On': [5947], 'hand,': [5950], 'RAGE/Cdc42-Rac': [5956], 'connections': [5968], 'thank': [5978], 'generously': [5983], 'providing': [5984, 5995, 6015], 'us': [5985, 5996, 6016], 'human': [5988], 'cDNA;': [5990], 'plasmids': [6000], 'Cdc42;': [6009], 'Peränen': [6013], 'excellent': [6022], 'technical': [6023], 'assistance': [6024], 'Eeva-Liisa': [6026], 'Saarikalle': [6027], 'Seija': [6029], 'Lehto': [6030], 'gratefully': [6032], 'acknowledged.': [6033]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2026885016', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 14}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 20}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 15}, {'year': 2017, 'cited_by_count': 24}, {'year': 2016, 'cited_by_count': 25}, {'year': 2015, 'cited_by_count': 25}, {'year': 2014, 'cited_by_count': 31}, {'year': 2013, 'cited_by_count': 32}, {'year': 2012, 'cited_by_count': 41}], 'updated_date': '2024-12-15T22:47:09.789685', 'created_date': '2016-06-24'}