Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2025509227', 'doi': 'https://doi.org/10.1136/sti.47.5.348', 'title': 'Clinical progression of ocular syphilis and neurosyphilis despite treatment with massive doses of penicillin. Failure to demonstrate treponemes in affected tissues.', 'display_name': 'Clinical progression of ocular syphilis and neurosyphilis despite treatment with massive doses of penicillin. Failure to demonstrate treponemes in affected tissues.', 'publication_year': 1971, 'publication_date': '1971-10-01', 'ids': {'openalex': 'https://openalex.org/W2025509227', 'doi': 'https://doi.org/10.1136/sti.47.5.348', 'mag': '2025509227', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/5123624', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1048223'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/sti.47.5.348', 'pdf_url': 'https://sti.bmj.com/content/sextrans/47/5/348.full.pdf', 'source': {'id': 'https://openalex.org/S112197712', 'display_name': 'Sexually Transmitted Infections', 'issn_l': '1368-4973', 'issn': ['1368-4973', '1472-3263'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://sti.bmj.com/content/sextrans/47/5/348.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5081016995', 'display_name': 'C N Sowmini', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801220108', 'display_name': 'Government General Hospital', 'ror': 'https://ror.org/05qkf9y72', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801220108']}, {'id': 'https://openalex.org/I159337121', 'display_name': 'Madras Medical College', 'ror': 'https://ror.org/050ztxn78', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I159337121']}], 'countries': ['IN'], 'is_corresponding': True, 'raw_author_name': 'C N Sowmini', 'raw_affiliation_strings': ['From the Institute of Venereology, Government General Hospital, and the Department of Venereology, Madras Medical College, Madras-3, India'], 'affiliations': [{'raw_affiliation_string': 'From the Institute of Venereology, Government General Hospital, and the Department of Venereology, Madras Medical College, Madras-3, India', 'institution_ids': ['https://openalex.org/I2801220108', 'https://openalex.org/I159337121']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5081016995'], 'corresponding_institution_ids': ['https://openalex.org/I2801220108', 'https://openalex.org/I159337121'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 3, 'citation_normalized_percentile': {'value': 0.63527, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 71, 'max': 73}, 'biblio': {'volume': '47', 'issue': '5', 'first_page': '348', 'last_page': '355'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11934', 'display_name': 'Biological Basis and Clinical Management of Syphilis', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11934', 'display_name': 'Biological Basis and Clinical Management of Syphilis', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11117', 'display_name': 'Hypersensitivity Reactions to Drugs and Medications', 'score': 0.9278, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10428', 'display_name': 'Vaginal Microbiome and Sexually Transmitted Infections', 'score': 0.9238, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/neurosyphilis', 'display_name': 'Neurosyphilis', 'score': 0.595912}, {'id': 'https://openalex.org/keywords/syphilis', 'display_name': 'Syphilis', 'score': 0.519588}, {'id': 'https://openalex.org/keywords/syphilis-serodiagnosis', 'display_name': 'Syphilis Serodiagnosis', 'score': 0.5136673}, {'id': 'https://openalex.org/keywords/ocular-manifestations', 'display_name': 'Ocular Manifestations', 'score': 0.507402}], 'concepts': [{'id': 'https://openalex.org/C2781319584', 'wikidata': 'https://www.wikidata.org/wiki/Q7888578', 'display_name': 'Neurosyphilis', 'level': 4, 'score': 0.96014607}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.89466685}, {'id': 'https://openalex.org/C2776983459', 'wikidata': 'https://www.wikidata.org/wiki/Q41083', 'display_name': 'Syphilis', 'level': 3, 'score': 0.8941704}, {'id': 'https://openalex.org/C174802600', 'wikidata': 'https://www.wikidata.org/wiki/Q12190', 'display_name': 'Penicillin', 'level': 3, 'score': 0.8036129}, {'id': 'https://openalex.org/C2780187896', 'wikidata': 'https://www.wikidata.org/wiki/Q134745', 'display_name': 'Treponema', 'level': 4, 'score': 0.63506484}, {'id': 'https://openalex.org/C2908804808', 'wikidata': 'https://www.wikidata.org/wiki/Q41083', 'display_name': 'Syphilis Serodiagnosis', 'level': 4, 'score': 0.5136673}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.4776529}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.42963222}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.4246981}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.33863312}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.08827448}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005128', 'descriptor_name': 'Eye Diseases', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D009494', 'descriptor_name': 'Neurosyphilis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D010406', 'descriptor_name': 'Penicillins', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D013587', 'descriptor_name': 'Syphilis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D013587', 'descriptor_name': 'Syphilis', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001177', 'descriptor_name': 'Arthropathy, Neurogenic', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D001177', 'descriptor_name': 'Arthropathy, Neurogenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002908', 'descriptor_name': 'Chronic Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005128', 'descriptor_name': 'Eye Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005901', 'descriptor_name': 'Glaucoma', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D005901', 'descriptor_name': 'Glaucoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007500', 'descriptor_name': 'Iritis', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D007500', 'descriptor_name': 'Iritis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007634', 'descriptor_name': 'Keratitis', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D007634', 'descriptor_name': 'Keratitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009494', 'descriptor_name': 'Neurosyphilis', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': False}, {'descriptor_ui': 'D009494', 'descriptor_name': 'Neurosyphilis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009748', 'descriptor_name': 'Nutrition Disorders', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D009748', 'descriptor_name': 'Nutrition Disorders', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009896', 'descriptor_name': 'Optic Atrophy', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D009896', 'descriptor_name': 'Optic Atrophy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010406', 'descriptor_name': 'Penicillins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013587', 'descriptor_name': 'Syphilis', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D013587', 'descriptor_name': 'Syphilis', 'qualifier_ui': 'Q000134', 'qualifier_name': 'cerebrospinal fluid', 'is_major_topic': False}, {'descriptor_ui': 'D013587', 'descriptor_name': 'Syphilis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013588', 'descriptor_name': 'Syphilis Serodiagnosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013590', 'descriptor_name': 'Syphilis, Congenital', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013590', 'descriptor_name': 'Syphilis, Congenital', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D013606', 'descriptor_name': 'Tabes Dorsalis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013606', 'descriptor_name': 'Tabes Dorsalis', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D014376', 'descriptor_name': 'Tuberculosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014376', 'descriptor_name': 'Tuberculosis', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/sti.47.5.348', 'pdf_url': 'https://sti.bmj.com/content/sextrans/47/5/348.full.pdf', 'source': {'id': 'https://openalex.org/S112197712', 'display_name': 'Sexually Transmitted Infections', 'issn_l': '1368-4973', 'issn': ['1368-4973', '1472-3263'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1048223', 'pdf_url': 'https://europepmc.org/articles/pmc1048223?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1048223', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/5123624', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/sti.47.5.348', 'pdf_url': 'https://sti.bmj.com/content/sextrans/47/5/348.full.pdf', 'source': {'id': 'https://openalex.org/S112197712', 'display_name': 'Sexually Transmitted Infections', 'issn_l': '1368-4973', 'issn': ['1368-4973', '1472-3263'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.81, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 3, 'referenced_works': ['https://openalex.org/W1989965447', 'https://openalex.org/W2395161513', 'https://openalex.org/W2611463800'], 'related_works': ['https://openalex.org/W88550938', 'https://openalex.org/W4377939159', 'https://openalex.org/W4220771317', 'https://openalex.org/W2968974283', 'https://openalex.org/W2411753238', 'https://openalex.org/W2139551294', 'https://openalex.org/W2096866463', 'https://openalex.org/W2049221070', 'https://openalex.org/W2025945292', 'https://openalex.org/W1983196939'], 'abstract_inverted_index': {'Clinical': [0], 'progression': [1], 'of': [2], 'ocular': [3], 'syphilis': [4], 'and': [5], 'neurosyphilis': [6], 'despite': [7], 'treatment': [8]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2025509227', 'counts_by_year': [], 'updated_date': '2024-09-11T23:16:42.084753', 'created_date': '2016-06-24'}