Publication Information

{'id': 'https://openalex.org/W2025137231', 'doi': 'https://doi.org/10.1101/sqb.1976.040.01.021', 'title': 'Characterization of Torpedo californica Acetylcholine Receptor: Its Subunit Composition and Ligand-binding Properties', 'display_name': 'Characterization of Torpedo californica Acetylcholine Receptor: Its Subunit Composition and Ligand-binding Properties', 'publication_year': 1976, 'publication_date': '1976-01-01', 'ids': {'openalex': 'https://openalex.org/W2025137231', 'doi': 'https://doi.org/10.1101/sqb.1976.040.01.021', 'mag': '2025137231', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1065525'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1101/sqb.1976.040.01.021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S78756772', 'display_name': 'Cold Spring Harbor Symposia on Quantitative Biology', 'issn_l': '0091-7451', 'issn': ['0091-7451', '1943-4456'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103458756', 'display_name': 'Michael A. Raftery', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M. A. Raftery', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003537159', 'display_name': 'Richard Vandlen', 'orcid': 'https://orcid.org/0000-0002-0477-3807'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'R. L. Vandlen', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065947748', 'display_name': 'K. Reed', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'K. L. Reed', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5057196413', 'display_name': 'T. Lee', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'T. Lee', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 11.379, 'has_fulltext': False, 'cited_by_count': 153, 'citation_normalized_percentile': {'value': 0.817847, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '40', 'issue': '0', 'first_page': '193', 'last_page': '202'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11818', 'display_name': 'Nicotinic Acetylcholine Receptors Study', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11818', 'display_name': 'Nicotinic Acetylcholine Receptors Study', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11641', 'display_name': 'Insect and Pesticide Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1109', 'display_name': 'Insect Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/electrophorus', 'display_name': 'Electrophorus', 'score': 0.9888631}], 'concepts': [{'id': 'https://openalex.org/C123419017', 'wikidata': 'https://www.wikidata.org/wiki/Q7826734', 'display_name': 'Torpedo', 'level': 4, 'score': 0.9917729}, {'id': 'https://openalex.org/C158685282', 'wikidata': 'https://www.wikidata.org/wiki/Q429766', 'display_name': 'Electrophorus', 'level': 5, 'score': 0.9888631}, {'id': 'https://openalex.org/C80161118', 'wikidata': 'https://www.wikidata.org/wiki/Q408520', 'display_name': 'Acetylcholine receptor', 'level': 3, 'score': 0.8904867}, {'id': 'https://openalex.org/C2779570518', 'wikidata': 'https://www.wikidata.org/wiki/Q412256', 'display_name': 'Nicotinic acetylcholine receptor', 'level': 4, 'score': 0.6119811}, {'id': 'https://openalex.org/C104292427', 'wikidata': 'https://www.wikidata.org/wiki/Q899781', 'display_name': 'Protein subunit', 'level': 3, 'score': 0.57240325}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.56382596}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.5322169}, {'id': 'https://openalex.org/C188987157', 'wikidata': 'https://www.wikidata.org/wiki/Q7030581', 'display_name': 'Nicotinic agonist', 'level': 3, 'score': 0.50177336}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.47793534}, {'id': 'https://openalex.org/C2775910092', 'wikidata': 'https://www.wikidata.org/wiki/Q180623', 'display_name': 'Acetylcholine', 'level': 2, 'score': 0.46964023}, {'id': 'https://openalex.org/C2777240379', 'wikidata': 'https://www.wikidata.org/wiki/Q776995', 'display_name': 'Neuromuscular junction', 'level': 2, 'score': 0.41358355}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.37093413}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33609354}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.0826287}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.05841139}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000109', 'descriptor_name': 'Acetylcholine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008566', 'descriptor_name': 'Membranes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011950', 'descriptor_name': 'Receptors, Cholinergic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000109', 'descriptor_name': 'Acetylcholine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000110', 'descriptor_name': 'Acetylcholinesterase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000110', 'descriptor_name': 'Acetylcholinesterase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001667', 'descriptor_name': 'Binding, Competitive', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002038', 'descriptor_name': 'Bungarotoxins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002038', 'descriptor_name': 'Bungarotoxins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002217', 'descriptor_name': 'Carbachol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002217', 'descriptor_name': 'Carbachol', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003650', 'descriptor_name': 'Decamethonium Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003650', 'descriptor_name': 'Decamethonium Compounds', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004557', 'descriptor_name': 'Electric Organ', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005399', 'descriptor_name': 'Fishes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006584', 'descriptor_name': 'Hexamethonium Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006584', 'descriptor_name': 'Hexamethonium Compounds', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008024', 'descriptor_name': 'Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008566', 'descriptor_name': 'Membranes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008970', 'descriptor_name': 'Molecular Weight', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1101/sqb.1976.040.01.021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S78756772', 'display_name': 'Cold Spring Harbor Symposia on Quantitative Biology', 'issn_l': '0091-7451', 'issn': ['0091-7451', '1943-4456'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1065525', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Life below water', 'id': 'https://metadata.un.org/sdg/14', 'score': 0.91}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 1, 'referenced_works': ['https://openalex.org/W1506578135'], 'related_works': ['https://openalex.org/W81472463', 'https://openalex.org/W785279518', 'https://openalex.org/W2594449112', 'https://openalex.org/W2142055365', 'https://openalex.org/W2129900022', 'https://openalex.org/W2085533367', 'https://openalex.org/W2072353469', 'https://openalex.org/W2026016956', 'https://openalex.org/W2025137231', 'https://openalex.org/W196396901'], 'abstract_inverted_index': {'The': [0], 'initial': [1], 'observation': [2], 'of': [3, 6, 10, 43, 51, 57, 66, 86], 'the': [4, 11, 41, 47, 63, 80], 'specificity': [5], 'in': [7], 'vivo': [8], 'blockade': [9], 'nicotinic': [12], 'acetylcholine': [13], 'receptor': [14], '(AChR)': [15], 'by': [16], 'neurotoxins': [17], 'from': [18, 26, 62, 93, 101], 'Bungarus': [19], 'multicinctus': [20], 'α-toxin': [21], '(α-BGT)': [22], 'and': [23, 30, 70, 105, 112], 'similar': [24], 'toxins': [25], 'Naja': [27], 'species': [28], '(Lee': [29], 'Chang': [31], '1966;': [32], 'Lee': [33], 'et': [34, 97, 109], 'al.': [35, 98, 110], '1967)': [36], 'afforded': [37], 'unique': [38], 'tools': [39], 'for': [40, 54], 'characterization': [42], 'these': [44], 'receptors': [45], 'at': [46, 79], 'biochemical': [48], 'level.': [49], 'Quantities': [50], 'AChR': [52], 'suitable': [53], 'such': [55], 'types': [56, 85], 'study': [58], 'are': [59, 76], 'available': [60], 'only': [61], 'electric': [64], 'tissues': [65], 'Electrophorus': [67], 'electricus,': [68], 'Torpedo': [69, 94, 102], 'Narcine': [71], 'species.': [72], 'In': [73], 'vitro': [74], 'studies': [75], 'carried': [77], 'out': [78], 'present': [81], 'time': [82], 'with': [83], 'two': [84], 'preparations:': [87], '(1)': [88], 'highly': [89], 'enriched': [90], 'membrane': [91], 'fragments': [92], 'marmorata': [95], '(Cohen': [96], '1972)': [99], 'or': [100], 'californica': [103], '(Duguid': [104], 'Raftery': [106], '1973;': [107], 'Reed': [108], '1975)': [111], '(2)': [113], 'detergent-solubilized,': [114], 'purified': [115], 'AChR.': [116]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2025137231', 'counts_by_year': [{'year': 2016, 'cited_by_count': 3}], 'updated_date': '2024-12-10T02:25:37.273926', 'created_date': '2016-06-24'}