Title: Nonlinear HCV and linear ALT dynamics in serum during high dose interferon
Abstract: We not:ced no sigcaficant ditferences in race, age, virology, or response to therapy.(>0.05).Fisher exact test was used to compare the characteristic data.hnear regression analysts however showed a significant (p = 0.05) linear relationship between ALT and lwer fibrosis on biopsies Conclusion Our stnd:es indicate that a normal ALT (0-50 IU/L) did not preclude more severe liver inJUry in a significant percent of cases Iherefore, the use of ALT in patients with HCV infection is not a p,~dictable indicator of significant underlying liver disease.T1268