Publication Information

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735], 'grade': [184, 231, 251, 293, 313, 324, 367], 'bladder': [185, 205, 220, 232, 252, 294, 314, 325, 332, 368, 402, 414, 579, 996, 1011, 1235], 'cancer': [186, 206, 221, 233, 241, 253, 315, 326, 333, 369, 415, 580, 761, 1012], 'is': [187, 503, 1014, 1062], 'an': [188, 699], 'extremely': [189], 'aggressive': [190], 'malignancy': [191], 'associated': [192, 427], 'with': [193, 229, 291, 322, 365, 413, 1311], 'high': [194, 230, 250, 292, 312, 323, 366], 'rates': [195], 'morbidity': [197], 'mortality.': [199], 'Understanding': [200], 'how': [201], 'exosomes': [202, 288, 346, 358, 376, 522, 540, 564, 599, 639], 'may': [203], 'affect': [204], 'progression': [207, 242], 'could': [208, 430], 'reveal': [209], 'novel': [210, 433, 505, 981], 'therapeutic': [211, 434], 'targets.': [212], 'Materials': [213, 1218], 'Methods:': [215], 'derived': [217, 407], 'from': [218, 248, 289, 311, 360, 377, 408, 541], 'human': [219, 597, 1010], 'cell': [222, 254, 261, 355, 403, 542, 706, 803, 825, 857, 892, 895, 941], 'lines': [223], 'the': [225, 237, 249, 258, 318, 361, 378, 409, 890, 915, 1108, 1273, 1282], 'urine': [226, 319, 362, 379, 410], 'patients': [228, 290, 321, 364, 412, 1070], 'were': [234, 264, 302], 'assessed': [235], 'for': [236, 266, 275, 600, 800, 992, 1146, 1195], 'ability': [238], 'promote': [240, 464], 'in': [243, 286, 740, 805, 889, 995, 1015, 1039, 1064, 1112, 1153, 1171], 'standard': [244], 'assays.': [245], 'purified': [247, 359], 'line': [255, 262], 'TCC-SUP': [256], 'nonmalignant': [259], 'urothelial': [260, 352], 'SV-HUC': [263, 1239], 'submitted': [265], 'mass': [267], 'spectrometry': [268], 'analysis.': [269, 277, 767], 'EDIL-3': [270, 284, 301, 306, 340, 373, 383, 400], 'was': [271, 280], 'identified': [272], 'selected': [274], 'further': [276], 'Western': [278], 'blot': [279], 'done': [281], 'determine': [283], 'levels': [285, 374], 'urinary': [287, 598], 'cancer.': [295, 997], 'shRNA': [296], 'gene': [297, 912], 'knockdown': [298], 'recombinant': [300], 'applied': [303], 'study': [305], 'function.': [307, 781], 'Results:': [308], 'isolated': [310], 'cells': [316, 334, 644, 1262], 'promoted': [327], 'angiogenesis': [328], 'migration': [330, 804, 942], 'endothelial': [336, 354, 824, 856, 894], 'cells.': [337, 511, 624, 1240], 'We': [338], 'silenced': [339], 'expression': [341, 736], 'found': [343], 'that': [344, 463], 'shEDIL-3': [345], 'did': [347], 'not': [348], 'facilitate': [349], 'angiogenesis,': [350], 'migration.': [356, 404], 'Moreover,': [357], 'contained': [370], 'significantly': [371], 'higher': [372], 'than': [375], 'healthy': [381], 'controls.': [382], 'activated': [384], 'epidermal': [385, 393, 684, 945], 'growth': [386, 394, 466, 685, 722, 930, 946, 1007, 1059], 'factor': [387, 395, 686, 718, 947, 1008, 1033, 1060], 'receptor': [388, 396, 948, 965], 'signaling': [389, 397], 'while': [390], 'blockade': [391], 'abrogated': [398], 'this': [399, 1336, 1352, 1368, 1384, 1405, 1426, 1442, 1459, 1475], 'induced': [401], 'Conclusions:': [405], 'contains': [416], 'bioactive': [417], 'molecules': [418], 'such': [419], 'as': [420, 443], 'EDIL-3.': [421], 'Identifying': [422], 'these': [423], 'components': [424], 'their': [426, 887], 'oncogenic': [428], 'pathways': [429], 'lead': [431], 'targets': [435], 'treatment': [437], 'strategies.': [438], 'References': [439], '1': [440], ':': [441, 456, 479, 496, 520, 535, 562, 575, 590, 610, 637, 658, 674, 697, 714, 734, 756, 776, 790, 814, 837, 852, 872, 906, 928, 958, 979, 1005, 1029, 1055], 'Exosomes/microvesicles': [442], 'a': [444, 504, 646, 795, 818, 1017, 1036], 'mechanism': [445, 506, 982], 'cell-to-cell': [447], 'communication.': [448], 'Kidney': [449, 603], 'Int2010;': [450], '78:': [451], '838.': [452], 'Google': [453, 476, 493, 517, 532, 559, 572, 587, 607, 634, 655, 671, 694, 711, 731, 753, 773, 787, 811, 834, 849, 869, 903, 925, 955, 976, 1002, 1026, 1052, 1084], 'Scholar': [454, 477, 494, 518, 533, 560, 573, 588, 608, 635, 656, 672, 695, 712, 732, 754, 774, 788, 812, 835, 850, 870, 904, 926, 956, 977, 1003, 1027, 1053, 1085], '2': [455, 961], 'Glioblastoma': [457], 'microvesicles': [458, 481, 613], 'transport': [459], 'RNA': [460], 'proteins': [462], 'tumour': [465], 'provide': [468], 'diagnostic': [469], 'biomarkers.': [470], 'Nat': [471, 489, 512, 651, 782, 807, 830, 865], 'Cell': [472, 513, 550, 583, 972, 1021], 'Biol2008;': [473], '10:': [474, 669, 771], '1470.': [475], '3': [478], 'Tumour': [480], 'contain': [482], 'retrotransposon': [483], 'elements': [484], 'amplified': [486], 'oncogene': [487], 'sequences.': [488], 'Commun2011;': [490], '2:': [491, 785, 809, 832], '180.': [492], '4': [495], 'Exosome-mediated': [497], 'transfer': [498], 'mRNAs': [500], 'microRNAs': [502], 'genetic': [508], 'exchange': [509], 'between': [510], 'Biol2007;': [514], '9:': [515, 585, 1024], '654.': [516], '5': [519, 885], 'trigger': [523], 'fibroblast': [524], 'myofibroblast': [526], 'differentiation.': [527], 'Res2010;': [529], '70:': [530], '9621.': [531], '6': [534], 'Isolation': [536], 'characterization': [538], 'culture': [543], 'supernatants': [544], 'biological': [546], 'fluids.': [547], 'Curr': [548], 'Protoc': [549], 'Biol2006;': [551], '.': [552], 'chapt': [553], '3,': [554, 556, 881], 'unit': [555], 'p': [557], '22.': [558], '7': [561], 'Urinary': [563, 1142], 'proteomics.': [566], 'Mass': [567], 'Spectrom': [568], 'Rev2011;': [569], '30:': [570], '1185.': [571], '8': [574, 1061], 'analysis': [577, 663, 801], 'exosomes.': [581, 844], 'Mol': [582, 1080], 'Proteomics2010;': [584], '1324.': [586], '9': [589], 'Collection,': [591], 'storage,': [592], 'preservation,': [593], 'normalization': [595], 'biomarker': [601], 'discovery.': [602], 'Int2006;': [604], '69:': [605], '1471.': [606], '10': [609], 'cell-derived': [612], 'induce': [614], 'transformation': [615], 'by': [616, 723, 842, 911, 1088, 1106, 1224, 1335, 1351, 1367, 1383, 1404, 1425, 1441, 1458, 1474], 'transferring': [617], 'tissue': [618], 'transglutaminase': [619], 'fibronectin': [621], 'recipient': [623], 'Proc': [625], 'Natl': [626], 'Acad': [627], 'Sci': [628], 'U': [629], 'S': [630], 'A2011;': [631], '108:': [632], '4852.': [633], '11': [636], 'Melanoma': [638], 'educate': [640], 'bone': [641], 'marrow': [642], 'progenitor': [643], 'toward': [645], 'pro-metastatic': [647], 'phenotype': [648], 'through': [649, 943], 'MET.': [650], 'Med2012;': [652, 1081], '18:': [653, 1082], '883.': [654], '12': [657], 'Microfluidic': [659], 'isolation': [660], 'transcriptome': [662], 'serum': [665], 'microvesicles.': [666], 'Lab': [667, 845], 'Chip2010;': [668], '505.': [670], '13': [673], 'The': [675, 715, 815, 873, 1144, 1241], 'extracellular': [676, 916], 'matrix': [677, 917], 'protein': [678, 918], 'Del1': [679, 719], 'induces': [680], 'apoptosis': [681, 1075], 'via': [682, 987], 'its': [683, 828], 'motif.': [687], 'Biochem': [688], 'Biophys': [689], 'Res': [690], 'Commun2010;': [691], '393:': [692], '757.': [693], '14': [696], 'Del-1,': [698], 'endogenous': [700], 'leukocyte-endothelial': [701], 'adhesion': [702, 876], 'inhibitor,': [703], 'limits': [704], 'inflammatory': [705], 'recruitment.': [707], 'Science2008;': [708], '322:': [709], '1101.': [710], '15': [713], 'embryonic': [716], 'angiogenic': [717], 'accelerates': [720], 'tumor': [721, 822, 843, 891], 'enhancing': [724], 'vascular': [725], 'formation.': [726], 'Microvasc': [727], 'Res2002;': [728], '64:': [729], '148.': [730], '16': [733], 'level': [737], 'EDIL3': [739], 'HCC': [741, 746], 'predicts': [742], 'poor': [743], 'prognosis': [744], 'patients.': [747], 'World': [748], 'J': [749, 898, 920, 950, 971, 1047], 'Gastroenterol2010;': [750], '16:': [751, 901], '4611.': [752], '17': [755], 'Predicting': [757], 'ulcerative': [758, 1068], 'colitis-associated': [759], 'colorectal': [760], 'using': [762], 'reverse-transcription': [763], 'polymerase': [764], 'chain': [765], 'reaction': [766], 'Clin': [768, 921, 1048], 'Colorectal': [769], 'Cancer2011;': 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[897], 'Prev2007;': [900], '517.': [902], '24': [905], 'Neovascularization': [907], 'ischemic': [909], 'tissues': [910], 'delivery': [913], 'Del-1.': [919], 'Invest2003;': [922], '112:': [923], '30.': [924], '25': [927], 'Epidermal': [929, 1006], 'factor-like': [931], 'repeats': [932], 'thrombospondins': [934], 'activate': [935], 'phospholipase': [936], 'Cgamma': [937], 'increase': [939], 'epithelial': [940], 'indirect': [944], 'activation.': [949], 'Biol': [951], 'Chem2009;': [952], '284:': [953], '6389.': [954], '26': [957], 'Integrin': [959], '1-dependent': [963], 'EGF': [964], 'activation': [966], 'at': [967], 'cell-cell': [968], 'contact': [969], 'sites.': [970], 'Sci2000;': [973], '113:': [974], '2139.': [975], '27': [978], 'A': [980, 1097], 'PPAR': [984], 'gamma': [985], 'EGFR': [988], 'signalling': [989], 'constitutes': [990], 'rational': [991], 'combination': [993], 'therapy': [994], 'PLoS': [998], 'One2013;': [999], '8:': [1000], 'e55997.': [1001], '28': [1004], 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