Title: Erk-independent Regulation of Growth in Pancreatic Carcinoma via Rap1
Abstract:Aims: For the small GTPase Rap1 it has been shown that it inhibits growth in pancreatic cancer cells. The underlying mechanism has not yet been fully clarified. Interestingly this effect of Rap1 mayno...Aims: For the small GTPase Rap1 it has been shown that it inhibits growth in pancreatic cancer cells. The underlying mechanism has not yet been fully clarified. Interestingly this effect of Rap1 maynot be due to interference to Ras effector function. There is evidence for additional functions of endogenous Rap1 in cellular differentiation, adhesion and cell migration.The aim of the present study was to explore the influence of endogenous Rap1 activation on pancreatic cell growth.Read More
Publication Year: 2005
Publication Date: 2005-05-01
Language: en
Type: article
Indexed In: ['crossref']
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