Title: The effect of vitamin D on the bones of young rats receiving diets low in calcium or phosphorus
Abstract: Weanling rats were maintained on diets adequate in phosphorus (0.42 per cent) but low in calcium (0.026 per cent) for 10 weeks. When vitamin D was included in the diet a condition showing certain similarities to osteoporosis was observed in the femur. In the absence of vitamin D the condition of the bones became increasingly osteomalacic and less porotic. Frank rickets was not produced in either of these circumstances. Diets adequate in calcium (0.6 per cent) but low in phosphorus (0.06 per cent) resulted in rickets even in the presence of vitamin D. The implications of these results are discussed in relation to the citrate content of the bone and the relative mobility of the skeletal calcium in the experimental conditions.
Publication Year: 1963
Publication Date: 1963-05-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 40
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