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5448, 5462, 5498, 5515, 5588, 5611, 5634, 5687, 5698, 5724, 5755, 5777, 5812, 5854, 5876, 5907, 5913, 5943, 5977, 6019, 6028, 6075, 6099, 6111, 6116, 6229, 6266, 6374, 6385, 6389, 6422, 6441, 6458, 6470, 6483, 6487, 6498, 6522, 6550, 6616, 6619, 6672, 6685, 6711, 6714, 6810, 6848, 6905, 6911, 6925, 6961, 6978, 7051, 7074, 7097, 7151, 7162, 7188, 7220, 7242, 7277, 7319, 7341, 7372, 7379, 7409, 7443, 7485, 7494, 7541, 7565, 7577, 7582], 'erythrocyte': [8, 219, 438, 689, 3333, 3584], 'plasma': [9, 220, 429, 3324], 'membrane.': [10, 221, 1124, 2123, 4020, 5023, 6485], 'We': [11, 222, 1158, 1702, 1825, 1881, 2008, 2860, 3194, 4055, 4539, 4601, 4724, 4781, 4908, 5760, 6094, 6242, 6369, 7225, 7560, 7683], 'have': [12, 223, 630, 768, 950, 1159, 1243, 1529, 1703, 1826, 1860, 1882, 2056, 2099, 2286, 2342, 2972, 3525, 3664, 3846, 4056, 4141, 4427, 4602, 4725, 4760, 4782, 4956, 4999, 5186, 5242, 5872, 6221, 6243, 6418, 6461, 6648, 6705, 7337], 'used': [13, 224, 801, 830, 1641, 3697, 3726, 4540], 'scanning': [14, 225], 'cysteine': [15, 63, 113, 226, 274, 324, 1183, 1238, 1262, 1272, 1389, 1643, 2062, 2190, 2865, 4080, 4136, 4160, 4170, 4287, 4542, 4962, 5090, 5765, 6424, 6552, 7230], 'mutagenesis': [16, 227, 992, 1239, 1644, 3888, 4137, 4543], 'and': [17, 40, 116, 124, 137, 139, 143, 152, 203, 228, 251, 327, 335, 348, 350, 354, 363, 414, 454, 527, 607, 642, 662, 723, 741, 811, 840, 862, 875, 901, 971, 1022, 1106, 1119, 1135, 1200, 1240, 1267, 1352, 1488, 1610, 1645, 1673, 1722, 1833, 1855, 1973, 2017, 2071, 2103, 2162, 2207, 2224, 2231, 2264, 2290, 2303, 2329, 2416, 2696, 2723, 2814, 2840, 3026, 3108, 3145, 3179, 3266, 3278, 3349, 3422, 3502, 3537, 3557, 3618, 3636, 3707, 3736, 3758, 3771, 3797, 3867, 3918, 4002, 4015, 4031, 4097, 4138, 4165, 4250, 4386, 4508, 4544, 4572, 4621, 4732, 4754, 4873, 4917, 4971, 5003, 5062, 5107, 5124, 5131, 5164, 5190, 5203, 5229, 5316, 5596, 5623, 5714, 5740, 5926, 6008, 6045, 6079, 6166, 6178, 6334, 6378, 6433, 6465, 6524, 6569, 6586, 6593, 6626, 6652, 6666, 6692, 6779, 7059, 7086, 7178, 7204, 7392, 7474, 7511, 7545, 7632, 7644, 7694], 'sulfhydryl-specific': [18, 229, 1283, 4181], 'chemistry': [19, 230, 1242, 1647, 4140, 4546], 'to': [20, 165, 175, 231, 376, 386, 664, 953, 1024, 1115, 1166, 1191, 1195, 1248, 1258, 1268, 1537, 1648, 1774, 1847, 1851, 1871, 1893, 1896, 1969, 1991, 1997, 2020, 2165, 2171, 2285, 2288, 2334, 2345, 2571, 2729, 2809, 2829, 2886, 2888, 2948, 2971, 3028, 3112, 3133, 3165, 3237, 3289, 3299, 3559, 3849, 3920, 4011, 4063, 4088, 4092, 4146, 4156, 4166, 4435, 4547, 4673, 4746, 4750, 4771, 4793, 4796, 4869, 4891, 4897, 4920, 5065, 5071, 5185, 5188, 5234, 5245, 5471, 5629, 5709, 5729, 5786, 5788, 5848, 5871, 5928, 6012, 6033, 6065, 6137, 6189, 6199, 6232, 6254, 6257, 6330, 6352, 6358, 6381, 6527, 6533, 6647, 6650, 6697, 6708, 6934, 7092, 7173, 7193, 7251, 7253, 7313, 7336, 7394, 7478, 7499, 7531, 7603, 7655, 7665], 'identify': [21, 94, 232, 305, 1167, 1249, 1649, 1872, 4064, 4147, 4548, 4772, 6233], 'pore-lining': [22, 199, 233, 410, 1650, 2613, 2778, 4549, 5513, 5678, 6976, 7142], 'residues': [23, 95, 163, 200, 234, 306, 374, 411, 767, 796, 866, 1168, 1184, 1209, 1250, 1263, 1273, 1407, 1545, 1651, 1707, 1835, 1873, 2000, 2023, 2129, 2191, 2248, 2341, 2455, 3201, 3663, 3692, 3762, 4065, 4081, 4106, 4148, 4161, 4171, 4305, 4443, 4550, 4606, 4734, 4773, 4900, 4923, 5029, 5091, 5148, 5241, 5355, 6101, 6234, 6361, 6384, 6491, 6553, 6610, 6704, 6818, 7567], 'in': [24, 235, 503, 560, 648, 658, 666, 687, 739, 959, 977, 987, 991, 1089, 1103, 1131, 1164, 1170, 1264, 1408, 1532, 1550, 1652, 1783, 1804, 2073, 2691, 2717, 2822, 2875, 2946, 3150, 3245, 3398, 3455, 3543, 3553, 3561, 3582, 3634, 3855, 3873, 3883, 3887, 3985, 3999, 4027, 4061, 4067, 4162, 4306, 4430, 4448, 4551, 4682, 4703, 4973, 5591, 5617, 5722, 5775, 5846, 6050, 6145, 6435, 7054, 7080, 7186, 7240, 7311, 7516, 7611], 'Ser643–Ser690': [26, 32, 237, 243, 2015, 4915, 6376], 'region': [27, 33, 238, 244, 1188, 1655, 1721, 1886, 1994, 2016, 2078, 2145, 2838, 3144, 4085, 4554, 4620, 4786, 4894, 4916, 4978, 5045, 5738, 6044, 6247, 6355, 6377, 6440, 6507, 7202, 7510], 'protein.': [30, 241, 1661, 4560], 'The': [31, 61, 173, 196, 242, 272, 384, 407, 682, 982, 1255, 1291, 2094, 2149, 2178, 2318, 2442, 2527, 2609, 2966, 3066, 3305, 3577, 3878, 4153, 4189, 4994, 5049, 5078, 5218, 5342, 5427, 5509, 5866, 5966, 6205, 6456, 6511, 6540, 6681, 6805, 6890, 6972, 7331, 7432, 7671], 'spans': [34, 245], 'transmembrane': [35, 48, 87, 103, 130, 160, 182, 246, 259, 298, 314, 341, 371, 393, 668, 804, 827, 833, 856, 1877, 1962, 2075, 2176, 2228, 2443, 3563, 3700, 3723, 3729, 3752, 4777, 4862, 4975, 5076, 5128, 5343, 6238, 6323, 6437, 6538, 6590, 6806], 'segment': [36, 247, 2076, 4976, 6438], '8': [37, 184, 248, 395, 2077, 4977, 6439], 'surrounds': [41, 252], 'Glu681,': [42, 253, 870, 958, 1890, 2166, 3300, 3766, 3854, 4790, 5066, 6200, 6251, 6528, 7666], 'which': [43, 85, 254, 296, 1109, 2112, 2167, 2594, 2718, 2811, 2998, 3205, 3296, 4005, 5012, 5067, 5494, 5618, 5711, 5898, 6105, 6196, 6474, 6529, 6957, 7081, 7175, 7363, 7571, 7662], 'may': [44, 153, 205, 255, 364, 416, 1136, 1957, 2623, 2812, 2843, 2849, 2950, 3059, 3311, 4032, 4857, 5523, 5712, 5743, 5749, 5850, 5959, 6211, 6318, 6986, 7176, 7207, 7214, 7315, 7425, 7677], 'reside': [45, 256, 1137, 1959, 2104, 4033, 4859, 5004, 6320, 6466], 'at': [46, 186, 257, 397, 1138, 1714, 1960, 1984, 2114, 2196, 2314, 2977, 3000, 3032, 3203, 3308, 4034, 4613, 4860, 4884, 5014, 5096, 5214, 5877, 5900, 5932, 6103, 6208, 6321, 6345, 6476, 6558, 6677, 7342, 7365, 7398, 7569, 7674], 'permeability': [49, 260, 1140, 1963, 3030, 3218, 3303, 4036, 4863, 5930, 6118, 6203, 6324, 7396, 7584, 7669], 'barrier.': [50, 261, 1964, 3219, 3304, 4864, 6119, 6204, 6325, 7585, 7670], 'Glu681': [51, 262, 986, 1037, 1096, 1112, 1127, 1966, 1996, 2019, 2622, 2628, 2683, 3033, 3212, 3882, 3933, 3992, 4008, 4023, 4040, 4866, 4896, 4919, 5522, 5528, 5583, 5933, 6112, 6327, 6357, 6380, 6985, 6991, 7046, 7399, 7578], 'also': [52, 263, 423, 1543, 2624, 3318, 4441, 5524, 6987], 'directly': [53, 264, 2154, 2846, 5054, 5746, 6516, 7210], 'interacts': [54, 265, 1152, 1981, 2629, 2720, 4049, 4881, 5529, 5620, 6342, 6992, 7083], 'with': [55, 119, 208, 266, 330, 419, 967, 973, 1153, 1390, 1780, 1982, 2173, 2192, 2233, 2453, 2498, 2545, 2630, 2721, 3156, 3208, 3293, 3863, 3869, 4050, 4288, 4679, 4882, 5073, 5092, 5133, 5353, 5398, 5445, 5530, 5621, 6056, 6108, 6193, 6343, 6535, 6554, 6595, 6816, 6861, 6908, 6993, 7084, 7522, 7574, 7659], 'some': [56, 267, 3061, 5961, 7427], 'anions': [57, 268, 1154, 2174, 2235, 2632, 4051, 5074, 5135, 5532, 6536, 6597, 6995], 'during': [58, 269, 1083, 1155, 1986, 2175, 2633, 3979, 4052, 4886, 5075, 5533, 6347, 6537, 6996], 'transport.': [60, 271, 1085, 2210, 3981, 5110, 6572], 'introduced': [62, 112, 273, 323, 1182, 2061, 2189, 2864, 4079, 4961, 5089, 5764, 6423, 6551, 7229], 'mutants': [64, 131, 141, 179, 275, 342, 352, 390, 2063, 2098, 2866, 2911, 4963, 4998, 5766, 5811, 6425, 6460, 7231, 7276], 'were': [65, 276, 2919, 5819, 7284], 'expressed': [66, 277, 502, 559, 3397, 3454], 'by': [67, 78, 91, 149, 278, 289, 302, 360, 674, 1095, 1198, 1282, 1539, 1798, 1853, 2087, 2269, 2872, 2923, 3116, 3569, 3991, 4095, 4180, 4437, 4697, 4752, 4987, 5169, 5772, 5823, 6016, 6449, 6631, 7237, 7288, 7482], 'transient': [68, 279], 'transfection': [69, 280], 'HEK293': [71, 282, 1785, 4684], 'cells.': [72, 283, 1786, 4685], 'Anion': [73, 284, 3040, 5940, 7406], 'exchange': [74, 108, 285, 319, 434, 641, 776, 980, 1042, 1133, 1660, 1782, 3115, 3329, 3536, 3672, 3876, 3938, 4029, 4559, 4681, 6015, 7481], 'activity': [75, 109, 286, 320], 'was': [76, 287, 989, 2168, 2883, 3163, 3885, 5068, 5783, 6063, 6530, 7248, 7529], 'assessed': [77, 288, 1287, 4185], 'measurement': [79, 290], 'changes': [81, 292], 'intracellular': [83, 140, 178, 193, 294, 351, 389, 404, 1118, 1776, 3279, 4014, 4675, 6179, 7645], 'pH,': [84, 295], 'follow': [86, 297], 'bicarbonate': [88, 299, 432, 3327], 'movement': [89, 300, 2541, 5441, 6904], 'mediated': [90, 301], 'AE1.': [92, 303, 779, 3675, 4039], 'To': [93, 304], 'that': [96, 145, 181, 307, 356, 392, 794, 1032, 1111, 1151, 1836, 1874, 1980, 2001, 2082, 2143, 2198, 2216, 2245, 2296, 2491, 2530, 2611, 2862, 3016, 3124, 3161, 3196, 3285, 3690, 3928, 4007, 4048, 4735, 4774, 4880, 4901, 4982, 5043, 5098, 5116, 5145, 5196, 5391, 5430, 5511, 5762, 5916, 6024, 6061, 6096, 6185, 6235, 6341, 6362, 6444, 6505, 6560, 6578, 6607, 6659, 6854, 6893, 6974, 7227, 7382, 7490, 7527, 7562, 7651], 'might': [97, 308, 2002, 4902, 6363], 'form': [98, 155, 309, 366, 1667, 1807, 2003, 2249, 2346, 3248, 4566, 4706, 4903, 5149, 5246, 6148, 6364, 6611, 6709, 7614], 'part': [99, 157, 310, 368, 772, 2256, 2347, 3668, 5156, 5247, 6618, 6710], 'an': [101, 312, 675, 1842, 2147, 2336, 2596, 3002, 3022, 3570, 4741, 5047, 5236, 5496, 5902, 5922, 6509, 6699, 6959, 7367, 7388], 'aqueous': [102, 313, 2337, 5237, 6700], 'pore,': [104, 315, 2201, 2958, 3121, 5101, 5858, 6021, 6563, 7323, 7487], 'we': [105, 316, 1177, 1204, 1663, 1758, 1859, 1989, 2214, 3159, 4074, 4101, 4562, 4657, 4759, 4889, 5114, 6059, 6220, 6350, 6576, 7525], 'measured': [106, 317], 'each': [111, 322, 1289, 4187], 'mutant': [114, 325, 3294, 6194, 7660], 'before': [115, 326], 'after': [117, 328, 3074, 5974, 7440], 'incubation': [118, 329], 'sulfhydryl': [121, 150, 332, 361, 1241, 1646, 1764, 1790, 2089, 2194, 2270, 2766, 3068, 3134, 4139, 4545, 4663, 4689, 4989, 5094, 5170, 5666, 5968, 6034, 6451, 6556, 6632, 7130, 7434, 7500], 'reagentspara-chloromercuribenzene': [122, 333], 'sulfonate': [123, 334], '2-(aminoethyl)methanethiosulfonate': [125, 336], 'hydrobromide.': [126, 337], 'Our': [127, 338, 3057, 5957, 6416, 6657, 7212, 7423], 'data': [128, 339, 2183, 3058, 3283, 5083, 5958, 6183, 6545, 7424, 7649], 'identified': [129, 197, 340, 408, 1205, 1531, 1544, 1723, 1827, 2057, 2128, 4102, 4429, 4442, 4622, 4726, 4957, 5028, 6419, 6490], 'A666C,': [132, 343], 'S667C,': [133, 344, 3180, 6080, 7546], 'L669C,': [134, 345], 'L673C,': [135, 346], 'L677C,': [136, 347], 'L680C': [138, 349], 'I684C': [142, 353], 'I688C': [144, 355], 'could': [146, 357, 2568, 2697, 5468, 5597, 6931, 7060], 'be': [147, 358, 1894, 2084, 2283, 2569, 2730, 2845, 4794, 4984, 5183, 5469, 5630, 5745, 6255, 6446, 6645, 6932, 7093, 7209], 'inhibited': [148, 359, 2085, 2247, 2871, 2922, 4985, 5147, 5771, 5822, 6447, 6609, 7236, 7287], 'reagents': [151, 362, 1284, 1765, 2090, 2203, 3135, 4182, 4664, 4990, 5103, 6035, 6452, 6565, 7501], 'therefore': [154, 365, 1160, 1958, 3267, 4057, 4858, 6167, 6319, 7633], 'a': [156, 159, 169, 367, 370, 380, 479, 482, 631, 634, 643, 714, 789, 1092, 1174, 1179, 1245, 1265, 1388, 1391, 1401, 1665, 1828, 1876, 2058, 2100, 2109, 2133, 2137, 2185, 2250, 2258, 2279, 2486, 2709, 2802, 2825, 2973, 3029, 3120, 3140, 3146, 3313, 3374, 3377, 3526, 3529, 3538, 3609, 3685, 3988, 4071, 4076, 4143, 4163, 4286, 4289, 4299, 4564, 4727, 4776, 4958, 5000, 5009, 5033, 5037, 5085, 5150, 5158, 5179, 5386, 5609, 5702, 5725, 5873, 5929, 6020, 6040, 6046, 6213, 6237, 6420, 6462, 6471, 6495, 6499, 6547, 6612, 6620, 6641, 6849, 7072, 7166, 7189, 7338, 7395, 7486, 7506, 7512, 7679], 'pore.': [161, 372, 1405, 1880, 2558, 2704, 2832, 2859, 4303, 4780, 5458, 5604, 5732, 5759, 6241, 6921, 7067, 7196, 7224, 7375], 'These': [162, 373], 'map': [164, 375], 'one': [166, 377, 1839, 1978, 2106, 2116, 2785, 4738, 4878, 5006, 5016, 5685, 6339, 6468, 6478, 7149], 'face': [167, 378, 1840, 2107, 2152, 2159, 2614, 2786, 2828, 4739, 5007, 5052, 5059, 5514, 5686, 5728, 6469, 6514, 6521, 6977, 7150, 7192], 'helical': [170, 189, 381, 400, 2101, 2139, 2151, 2803, 2827, 2837, 5001, 5039, 5051, 5703, 5727, 5737, 6463, 6501, 6513, 7167, 7191, 7201], 'wheel': [171, 382, 2140, 2804, 5040, 5704, 6502, 7168], 'plot.': [172, 383, 2805, 5705, 7169], 'ability': [174, 385], 'inhibit': [176, 387, 2208, 2887, 3113, 5108, 5787, 6013, 6570, 7252, 7479], 'two': [177, 188, 388, 399, 1763, 1789, 2261, 2292, 4662, 4688, 5161, 5192, 6623, 6654], 'suggests': [180, 391, 3015, 3139, 5915, 6039, 7381, 7505], 'helix': [183, 394, 2617, 5517, 6980], 'extends': [185, 396, 2113, 5013, 6475], 'least': [187, 398, 1985, 2115, 2978, 3001, 4885, 5015, 5878, 5901, 6346, 6477, 7343, 7366], 'turns': [190, 401], 'beyond': [191, 402, 2118, 5018, 6480], 'membrane': [194, 405, 430, 636, 690, 1375, 1897, 1907, 3225, 3243, 3325, 3531, 3585, 4273, 4797, 4807, 6125, 6143, 6258, 6268, 7591, 7609], 'surface.': [195, 406], 'hydrophobic': [198, 409, 2158, 2298, 2340, 2454, 2499, 2532, 2560, 5058, 5198, 5240, 5354, 5399, 5432, 5460, 6520, 6661, 6703, 6817, 6862, 6895, 6923], '(leucine,': [201, 412], 'isoleucine,': [202, 413, 1832, 2302, 4731, 5202, 6665], 'alanine)': [204, 415], 'limit': [206, 417], 'interactions': [207, 418], 'substrate': [209, 420, 2234, 5134, 6596], 'anions.': [210, 421], 'AE1,': [422, 1091, 1670, 1799, 1870, 2255, 3228, 3317, 3987, 4569, 4698, 4770, 5155, 6128, 6231, 6617, 7594], 'called': [424, 1671, 3319, 4570], 'Band': [425, 3320], '3,': [426, 3321], 'chloride': [431, 1074, 1412, 1470, 2355, 2880, 3326, 3970, 4310, 4368, 5255, 5780, 6718, 7245], 'protein': [435, 694, 713, 721, 1266, 1554, 1676, 2030, 2450, 3330, 3589, 3608, 3616, 4164, 4452, 4575, 4930, 5350, 6391, 6813], '(1Kopito': [439, 3334], 'R.R.': [440, 486, 541, 584, 616, 1049, 1685, 3335, 3381, 3436, 3479, 3511, 3945, 4584], 'Lodish': [441, 463, 3336, 3358], 'H.L.': [442, 3337], 'J.': [443, 465, 570, 617, 882, 907, 922, 938, 1011, 1050, 1217, 1222, 1308, 1323, 1423, 1440, 1456, 1476, 1564, 1625, 1686, 1734, 1739, 1912, 1927, 1943, 2034, 2039, 2366, 2383, 2404, 2639, 2654, 2670, 2742, 2895, 2986, 3084, 3089, 3338, 3360, 3465, 3512, 3778, 3803, 3818, 3834, 3907, 3946, 4114, 4119, 4206, 4221, 4321, 4338, 4354, 4374, 4462, 4523, 4585, 4633, 4638, 4812, 4827, 4843, 4934, 4939, 5266, 5283, 5304, 5539, 5554, 5570, 5642, 5795, 5886, 5984, 5989, 6273, 6288, 6304, 6395, 6400, 6729, 6746, 6767, 7002, 7017, 7033, 7105, 7260, 7351, 7450, 7455], 'Cell.': [444, 595, 3339, 3490], 'Biochem.': [445, 2585, 3340, 5485, 6948], '1985;': [446, 3341], '29:': [447, 3342], '1-17Crossref': [448, 3343], 'PubMed': [449, 474, 493, 522, 552, 579, 602, 622, 705, 895, 913, 931, 947, 1017, 1061, 1233, 1315, 1332, 1347, 1368, 1432, 1447, 1462, 1485, 1505, 1524, 1575, 1605, 1636, 1697, 1750, 1820, 1918, 1936, 1952, 2050, 2375, 2390, 2413, 2437, 2476, 2522, 2589, 2645, 2663, 2679, 2755, 2902, 2939, 2993, 3100, 3261, 3344, 3369, 3388, 3417, 3447, 3474, 3497, 3517, 3600, 3791, 3809, 3827, 3843, 3913, 3957, 4130, 4213, 4230, 4245, 4266, 4330, 4345, 4360, 4383, 4403, 4422, 4473, 4503, 4534, 4596, 4649, 4719, 4818, 4836, 4852, 4950, 5275, 5290, 5313, 5337, 5376, 5422, 5489, 5545, 5563, 5579, 5655, 5802, 5839, 5893, 6000, 6161, 6279, 6297, 6313, 6411, 6738, 6753, 6776, 6800, 6839, 6885, 6952, 7008, 7026, 7042, 7118, 7267, 7304, 7358, 7466, 7627], 'Scopus': [450, 494, 523, 553, 603, 706, 763, 896, 914, 1018, 1062, 1234, 1316, 1333, 1348, 1369, 1448, 1463, 1506, 1525, 1576, 1606, 1637, 1698, 1751, 1821, 1919, 2051, 2391, 2438, 2477, 2523, 2590, 2646, 2756, 2903, 2940, 2994, 3101, 3262, 3345, 3389, 3418, 3448, 3498, 3601, 3658, 3792, 3810, 3914, 3958, 4131, 4214, 4231, 4246, 4267, 4346, 4361, 4404, 4423, 4474, 4504, 4535, 4597, 4650, 4720, 4819, 4951, 5291, 5338, 5377, 5423, 5490, 5546, 5656, 5803, 5840, 5894, 6001, 6162, 6280, 6412, 6754, 6801, 6840, 6886, 6953, 7009, 7119, 7268, 7305, 7359, 7467, 7628], '(42)': [451, 3346], 'Google': [452, 475, 496, 525, 555, 580, 605, 623, 708, 765, 898, 916, 932, 948, 1020, 1064, 1236, 1318, 1335, 1350, 1371, 1433, 1450, 1465, 1486, 1508, 1527, 1578, 1608, 1639, 1700, 1753, 1823, 1921, 1937, 1953, 2053, 2376, 2393, 2414, 2440, 2479, 2525, 2592, 2648, 2664, 2680, 2758, 2905, 2942, 2996, 3103, 3264, 3347, 3370, 3391, 3420, 3450, 3475, 3500, 3518, 3603, 3660, 3794, 3812, 3828, 3844, 3916, 3960, 4133, 4216, 4233, 4248, 4269, 4331, 4348, 4363, 4384, 4406, 4425, 4476, 4506, 4537, 4599, 4652, 4722, 4821, 4837, 4853, 4953, 5276, 5293, 5314, 5340, 5379, 5425, 5492, 5548, 5564, 5580, 5658, 5805, 5842, 5896, 6003, 6164, 6282, 6298, 6314, 6414, 6739, 6756, 6777, 6803, 6842, 6888, 6955, 7011, 7027, 7043, 7121, 7270, 7307, 7361, 7469, 7630], 'Scholar)': [453, 526, 949, 1021, 1351, 1487, 1528, 3265, 3348, 3421, 3845, 3917, 4249, 4385, 4426, 6165, 7631], 'kidney': [455, 3350], '(2Brosius': [456, 3351], 'III,': [457, 3352], 'F.C.': [458, 3353], 'Alper': [459, 1009, 3354, 3905], 'S.L.': [460, 728, 1010, 2513, 3355, 3623, 3906, 5413, 6876], 'Garcia': [461, 3356], 'A.M.': [462, 3357], 'H.F.': [464, 3359], 'Biol.': [466, 571, 759, 923, 939, 1051, 1223, 1424, 1477, 1565, 1626, 1687, 1740, 1928, 1944, 2040, 2367, 2405, 2655, 2671, 3090, 3361, 3466, 3654, 3819, 3835, 3947, 4120, 4322, 4375, 4463, 4524, 4586, 4639, 4828, 4844, 4940, 5267, 5305, 5555, 5571, 5990, 6289, 6305, 6401, 6730, 6768, 7018, 7034, 7456], 'Chem.': [467, 572, 924, 940, 1052, 1224, 1425, 1478, 1566, 1627, 1688, 1741, 1929, 1945, 2041, 2368, 2406, 2656, 2672, 3091, 3362, 3467, 3820, 3836, 3948, 4121, 4323, 4376, 4464, 4525, 4587, 4640, 4829, 4845, 4941, 5268, 5306, 5556, 5572, 5991, 6290, 6306, 6402, 6731, 6769, 7019, 7035, 7457], '1989;': [468, 596, 3363, 3491], '264:': [469, 3364], '7784-7787Abstract': [470, 3365], 'Full': [471, 576, 599, 928, 944, 1056, 1058, 1228, 1230, 1429, 1444, 1482, 1521, 1570, 1572, 1631, 1633, 1692, 1694, 1745, 1747, 1933, 1949, 2045, 2047, 2372, 2387, 2410, 2434, 2471, 2473, 2660, 2676, 2899, 2990, 3095, 3097, 3366, 3471, 3494, 3824, 3840, 3952, 3954, 4125, 4127, 4327, 4342, 4380, 4419, 4468, 4470, 4529, 4531, 4591, 4593, 4644, 4646, 4833, 4849, 4945, 4947, 5272, 5287, 5310, 5334, 5371, 5373, 5560, 5576, 5799, 5890, 5995, 5997, 6294, 6310, 6406, 6408, 6735, 6750, 6773, 6797, 6834, 6836, 7023, 7039, 7264, 7355, 7461, 7463], 'Text': [472, 577, 600, 929, 945, 1057, 1059, 1229, 1231, 1430, 1445, 1483, 1522, 1571, 1573, 1632, 1634, 1693, 1695, 1746, 1748, 1934, 1950, 2046, 2048, 2373, 2388, 2411, 2435, 2472, 2474, 2661, 2677, 2900, 2991, 3096, 3098, 3367, 3472, 3495, 3825, 3841, 3953, 3955, 4126, 4128, 4328, 4343, 4381, 4420, 4469, 4471, 4530, 4532, 4592, 4594, 4645, 4647, 4834, 4850, 4946, 4948, 5273, 5288, 5311, 5335, 5372, 5374, 5561, 5577, 5800, 5891, 5996, 5998, 6295, 6311, 6407, 6409, 6736, 6751, 6774, 6798, 6835, 6837, 7024, 7040, 7265, 7356, 7462, 7464], 'PDF': [473, 578, 601, 930, 946, 1060, 1232, 1431, 1446, 1484, 1523, 1574, 1635, 1696, 1749, 1935, 1951, 2049, 2374, 2389, 2412, 2436, 2475, 2662, 2678, 2901, 2992, 3099, 3368, 3473, 3496, 3826, 3842, 3956, 4129, 4329, 4344, 4382, 4421, 4472, 4533, 4595, 4648, 4835, 4851, 4949, 5274, 5289, 5312, 5336, 5375, 5562, 5578, 5801, 5892, 5999, 6296, 6312, 6410, 6737, 6752, 6775, 6799, 6838, 7025, 7041, 7266, 7357, 7465], 'Scholar).': [476, 624, 899, 1065, 1372, 1701, 1754, 1824, 1954, 2441, 2480, 2526, 2681, 2906, 2943, 3056, 3104, 3371, 3519, 3661, 3795, 3961, 4134, 4270, 4538, 4600, 4653, 4723, 4854, 5341, 5380, 5426, 5581, 5806, 5843, 5956, 6004, 6315, 6415, 6804, 6843, 6889, 7044, 7122, 7271, 7308, 7422, 7470], 'member': [480, 3375], 'multigene': [483, 3378], 'family': [484, 3379], '(3Kopito': [485, 3380], 'Int.': [487, 3382], 'Rev.': [488, 2584, 3383, 5484, 6947], 'Cytol.': [489, 3384], '1990;': [490, 549, 3385, 3444], '123:': [491, 3386], '177-199Crossref': [492, 3387], '(166)': [495, 3390], 'Scholar);': [497, 556, 3392, 3451], 'AE2': [498, 3393], 'most': [500, 2157, 2536, 3395, 5057, 5436, 6519, 6899], 'broadly': [501, 3396], 'tissues': [504, 3399], 'such': [505, 2278, 3400, 5178, 6640], 'as': [506, 771, 1210, 1677, 1727, 1977, 2236, 3213, 3401, 3667, 4107, 4576, 4626, 4877, 5136, 6113, 6338, 6598, 7579], 'gastric': [507, 3402], 'parietal': [508, 3403], 'cells': [509, 3404], '(4Jöns': [510, 3405], 'T.': [511, 2465, 3406, 5365, 6828], 'Warrings': [512, 3407], 'B.': [513, 3052, 3408, 5952, 7418], 'Jöns': [514, 3409], 'A.': [515, 548, 1325, 1364, 1500, 1516, 1601, 2429, 2509, 2935, 3410, 3443, 4223, 4262, 4398, 4414, 4499, 5329, 5409, 5835, 6792, 6872, 7300], 'Drenckhahn': [516, 3411], 'D.': [517, 880, 2580, 2740, 3412, 3776, 5480, 5640, 6943, 7103], 'Histochemistry.': [518, 3413], '1994;': [519, 619, 1426, 1518, 2369, 2431, 3414, 3514, 4324, 4416, 5269, 5331, 6732, 6794], '102:': [520, 3415], '255-263Crossref': [521, 3416], '(41)': [524, 3419], 'choroid': [528, 3423], 'plexus': [529, 3424], '(5Lindsey': [530, 3425], 'A.E.': [531, 590, 1614, 3426, 3485, 4512], 'Schneider': [532, 593, 3427, 3488], 'K.': [533, 594, 1008, 3428, 3489, 3904], 'Simmons': [534, 587, 3429, 3482], 'D.M.': [535, 588, 3430, 3483], 'Baron': [536, 3431], 'R.': [537, 1219, 1557, 1736, 2036, 2457, 2517, 3086, 3432, 4116, 4455, 4635, 4936, 5357, 5417, 5986, 6397, 6820, 6880, 7452], 'Lee': [538, 585, 3433, 3480], 'B.S.': [539, 586, 3434, 3481], 'Kopito': [540, 615, 1048, 1218, 1684, 1735, 2035, 3085, 3435, 3510, 3944, 4115, 4583, 4634, 4935, 5985, 6396, 7451], 'Proc.': [542, 1358, 1595, 2929, 3437, 4256, 4493, 5829, 7294], 'Natl.': [543, 1359, 1596, 2930, 3438, 4257, 4494, 5830, 7295], 'Acad.': [544, 1360, 1597, 2931, 3439, 4258, 4495, 5831, 7296], 'Sci.': [545, 1361, 1598, 2932, 3440, 4259, 4496, 5832, 7297], 'U.': [546, 1362, 1599, 2933, 3441, 4260, 4497, 5833, 7298], 'S.': [547, 610, 878, 884, 906, 1321, 1363, 1600, 1911, 2638, 2738, 2744, 2934, 3442, 3505, 3774, 3780, 3802, 4219, 4261, 4498, 4811, 5538, 5638, 5644, 5834, 6272, 7001, 7101, 7107, 7299], '87:': [550, 3445], '5278-5282Crossref': [551, 3446], '(140)': [554, 1607, 3449, 4505], 'AE3': [557, 3452], 'excitable': [561, 3456], 'tissues:': [562, 3457], 'heart': [563, 3458], '(6Linn': [564, 3459], 'S.C.': [565, 3460], 'Kudrycki': [566, 3461], 'K.E.': [567, 3462], 'Schull': [568, 3463], 'G.E.': [569, 3464], '1992;': [573, 925, 1502, 1930, 2657, 3468, 3821, 4400, 4830, 5557, 6291, 7020], '267:': [574, 926, 1931, 2658, 3469, 3822, 4831, 5558, 6292, 7021], '7927-7935Abstract': [575, 3470], 'Scholar),': [581, 606, 1466, 1579, 1609, 2394, 2415, 2997, 3476, 3501, 4364, 4477, 4507, 5294, 5315, 5897, 6757, 6778, 7362], 'brain': [582, 3477], '(7Kopito': [583, 3478], 'Lindsey': [589, 3484], 'Morgans': [591, 611, 3486, 3506], 'C.W.': [592, 612, 3487, 3507], '59:': [597, 3492], '927-937Abstract': [598, 3493], '(204)': [604, 3499], 'retina': [608, 3503], '(8Kobayashi': [609, 3504], 'Casey': [613, 1220, 1737, 2037, 3087, 3508, 4117, 4636, 4937, 5987, 6398, 7453], 'J.R.': [614, 1221, 1681, 1738, 2038, 3088, 3509, 4118, 4580, 4637, 4938, 5988, 6399, 7454], 'Neurosci.': [618, 3513], '14:': [620, 3515], '6266-6279Crossref': [621, 3516], 'All': [625, 670, 2780, 3520, 3565, 5680, 7144], 'exchangers': [629, 672, 3524, 3567], 'two-domain': [632, 3527], 'structure:': [633, 3528], '55-kDa': [635, 3530], 'domain': [637, 646, 661, 3532, 3541, 3556], 'responsible': [638, 3533], 'for': [639, 716, 791, 1080, 1288, 1296, 1383, 2181, 2540, 3004, 3063, 3534, 3611, 3687, 3976, 4186, 4194, 4281, 5081, 5440, 5904, 5963, 6543, 6903, 7369, 7429, 7688], '43–77-kDa': [644, 3539], 'cytoplasmic': [645, 1720, 3540, 4619], 'involved': [647, 1130, 1169, 3542, 4026, 4066], 'cytoskeletal': [649, 3544], 'interactions.': [650, 3545], 'Membrane': [651, 3546], 'domains': [652, 3547], 'are': [653, 1849, 2130, 2267, 2326, 2867, 3110, 3548, 4748, 5030, 5167, 5226, 5767, 6010, 6492, 6629, 6689, 7232, 7476], 'highly': [654, 3549], 'conserved': [655, 1039, 3550, 3935], '(80%': [656, 3551], 'homology': [657, 3552], 'whole': [660, 3555], 'close': [663, 2808, 3558, 5708, 7172], '90%': [665, 3560], 'segments).': [669, 3564], 'function': [673, 724, 3568, 3619], 'electroneutral': [676, 3571], '"Ping-Pong"': [677, 3572], 'mechanism': [678, 777, 3573, 3673], 'Cl−/HCO3−': [680, 1781, 3575, 4680], 'exchange.': [681, 3576], 'high': [683, 2574, 3306, 3578, 5474, 6206, 6937, 7672], 'abundance': [684, 3579], '(50%': [691, 3586], 'integral': [693, 3588], '(9Fairbanks': [695, 3590], 'G.': [696, 1815, 3256, 3591, 4714, 6156, 7622], 'Steck': [697, 3592], 'T.L.': [698, 3593], 'Wallach': [699, 3594], 'D.F.H.': [700, 3595], 'Biochemistry.': [701, 891, 1311, 1328, 1343, 2751, 3596, 3787, 4209, 4226, 4241, 5651, 7114], '1971;': [702, 3597], '10:': [703, 3598], '2606-2617Crossref': [704, 3599], '(6158)': [707, 3602], 'Scholar))': [709, 3604], 'has': [710, 787, 1113, 1293, 1379, 1542, 1974, 2707, 3605, 3683, 4009, 4191, 4277, 4440, 4874, 5607, 6335, 7070], 'made': [711, 3606], 'model': [715, 790, 2274, 2693, 2710, 3012, 3610, 3686, 5174, 5593, 5610, 5912, 6636, 7056, 7073, 7378], 'study': [718, 3613], 'transport': [720, 961, 1088, 1253, 1281, 1301, 1548, 1553, 1769, 2634, 3615, 3857, 3984, 4151, 4179, 4199, 4446, 4451, 4668, 5534, 6997], 'structure': [722, 2484, 2854, 3617, 5384, 5754, 6847, 7219], '(10Reithmeier': [725, 3620], 'R.A.F.': [726, 755, 3621, 3650], 'Chan': [727, 3622], 'Popov': [729, 3624], 'M.': [730, 1002, 1004, 1340, 1436, 1453, 1473, 1498, 1559, 1809, 2379, 2401, 2891, 2982, 3250, 3625, 3898, 3900, 4238, 4334, 4351, 4371, 4396, 4457, 4708, 5279, 5301, 5791, 5882, 6150, 6742, 6764, 7256, 7347, 7616], 'Konings': [731, 3626], 'W.N.': [732, 3627], 'Kaback': [733, 1309, 1326, 1341, 3628, 4207, 4224, 4239], 'H.R.': [734, 1310, 1327, 3629, 4208, 4225], 'Lolkema': [735, 3630], 'J.S.': [736, 921, 1926, 2653, 3631, 3817, 4826, 5553, 6287, 7016], 'Transport': [737, 3041, 3632, 5941, 7407], 'Processes': [738, 3633], 'Eukaryotic': [740, 3635], 'Prokaryotic': [742, 3637], 'Organisms.': [743, 3638], '2.': [744, 3639], 'Elsevier': [745, 3049, 3640, 5949, 7415], 'Science': [746, 3050, 3641, 5950, 7416], 'Publishing': [747, 3642], 'Co.,': [748, 3643], 'Inc.,': [749, 3644], 'New': [750, 3645], 'York1996:': [751, 3646], '281-309Google': [752, 3647], 'Scholar,': [753, 917, 933, 1319, 1336, 1434, 1451, 1922, 1938, 2377, 2649, 2665, 3648, 3813, 3829, 4217, 4234, 4332, 4349, 4822, 4838, 5277, 5549, 5565, 6283, 6299, 6740, 7012, 7028], '11Reithmeier': [754, 3649], 'Curr.': [756, 3651], 'Opin.': [757, 3652], 'Struct.': [758, 3653], '1993;': [760, 1344, 1479, 2407, 3655, 4242, 4377, 5307, 6770], '3:': [761, 3656], '515-523Crossref': [762, 3657], '(94)': [764, 3659], 'Scholar).Several': [766], 'been': [769, 1294, 1530, 1975, 2343, 3665, 4192, 4428, 4875, 5243, 6336, 6706], 'implicated': [770, 1976, 3666, 4876, 6337], 'On': [780, 2211, 3676, 5111, 6573], 'basis': [782, 2213, 3678, 5113, 6575], 'indirect': [784, 3680], 'evidence,': [785, 3681], 'Passow': [786, 889, 2706, 2749, 3682, 3785, 5606, 5649, 7069, 7112], 'proposed': [788, 3684], 'translocation': [793, 1156, 1404, 1879, 2006, 2229, 2312, 2445, 2494, 2566, 2715, 2858, 2909, 2957, 3019, 3272, 3689, 4053, 4302, 4779, 4906, 5129, 5212, 5345, 5394, 5466, 5615, 5758, 5809, 5857, 5919, 6172, 6240, 6367, 6591, 6675, 6808, 6857, 6929, 7078, 7223, 7274, 7322, 7385, 7638], 'involves': [795, 3691], 'from': [797, 1189, 1710, 1866, 1902, 2763, 2795, 3274, 3693, 4086, 4609, 4766, 4802, 5663, 5695, 6174, 6227, 6263, 7127, 7159, 7640], 'TMs': [798, 3694], '1The': [799, 3695], 'abbreviations': [800, 829, 3696, 3725], 'are:': [802, 831, 3698, 3727], 'TM,': [803, 832, 3699, 3728], 'segment;': [805, 834, 3701, 3730], 'AE1C−,': [806, 835, 1672, 3702, 3731, 4571], 'cysteineless': [807, 836, 1276, 1666, 3703, 3732, 4174, 4565], 'AE1;': [808, 837, 3704, 3733], 'BCECF-AM,': [809, 838, 3705, 3734], '2′,7′-bis(2-carboxyethyl)-(5': [810, 839, 3706, 3735], '6)-carboxyfluorescein,': [812, 841, 3708, 3737], 'acetoxymethyl': [813, 842, 3709, 3738], 'ester;': [814, 843, 3710, 3739], 'biotin': [815, 844, 3711, 3740], 'maleimide,': [816, 845, 3712, 3741], '3-(N-maleimidylpropionyl)biocytin;': [817, 846, 3713, 3742], 'MTSEA,': [818, 847, 2291, 3169, 3714, 3743, 5191, 6069, 6653, 7535], '2-(aminoethyl)methanethiosulfonate,': [819, 848, 3715, 3744], 'hydrobromide;': [820, 849, 3716, 3745], 'pCMBS,': [821, 850, 3166, 3717, 3746, 6066, 7532], 'para-chloromercuribenzene': [822, 851, 3718, 3747], 'sulfonate;': [823, 852, 3719, 3748], 'CFTR,': [824, 853, 3720, 3749], 'cystic': [825, 854, 1410, 2353, 3721, 3750, 4308, 5253, 6716], 'fibrosis': [826, 855, 1411, 2354, 3722, 3751, 4309, 5254, 6717], 'regulator.1The': [828, 3724], 'regulator.': [857, 3753], '5,': [858, 3754], '8,': [859, 3755], '10,': [860, 3756], '12,': [861, 3757], '13,': [863, 3759], 'including': [864, 3760], 'mouse': [865, 995, 1029, 3761, 3891, 3925], 'Glu472,': [867, 3763], 'Glu535,': [868, 3764], 'Lys539,': [869, 3765], 'His703,': [871, 3767], 'Arg731,': [872, 3768], 'His735,': [873, 3769], 'His816,': [874, 3770], 'His834': [876, 3772], '(12Müller-Berger': [877, 2737, 3773, 5637, 7100], 'Karbach': [879, 2739, 3775, 5639, 7102], 'Konig': [881, 2741, 3777, 5641, 7104], 'Lepke': [883, 2743, 3779, 5643, 7106], 'Wood': [885, 2745, 3781, 5645, 7108], 'P.G.': [886, 2746, 3782, 5646, 7109], 'Appelhans': [887, 2747, 3783, 5647, 7110], 'H.': [888, 890, 2748, 2750, 3784, 3786, 5648, 5650, 7111, 7113], '1995;': [892, 1053, 1365, 1689, 2752, 2936, 3788, 3949, 4263, 4588, 5652, 5836, 7115, 7301], '34:': [893, 2753, 3789, 5653, 7116], '9315-9324Crossref': [894, 2754, 3790, 5654, 7117], '(50)': [897, 915, 1920, 2647, 2757, 3793, 3811, 4820, 5547, 5657, 6281, 7010, 7120], 'Jennings': [900, 3038, 3796, 5938, 7404], 'co-workers': [902, 3798], '(13Jennings': [903, 1908, 2635, 3799, 4808, 5535, 6269, 6998], 'M.L.': [904, 919, 935, 1909, 1924, 1940, 2636, 2651, 2667, 3035, 3039, 3800, 3815, 3831, 4809, 4824, 4840, 5536, 5551, 5567, 5935, 5939, 6270, 6285, 6301, 6999, 7014, 7030, 7401, 7405], 'Al-Rhaiyel': [905, 1910, 2637, 3801, 4810, 5537, 6271, 7000], 'Gen.': [908, 1012, 1457, 1913, 2640, 3804, 3908, 4355, 4813, 5540, 6274, 7003], 'Physiol.': [909, 1013, 1458, 1914, 2641, 3805, 3909, 4356, 4814, 5541, 6275, 7004], '1988;': [910, 1915, 2642, 3806, 4815, 5542, 6276, 7005], '92:': [911, 1366, 1916, 2643, 2937, 3807, 4264, 4816, 5543, 5837, 6277, 7006, 7302], '161-178Crossref': [912, 1917, 2644, 3808, 4817, 5544, 6278, 7007], '14Jennings': [918, 1923, 2650, 3814, 4823, 5550, 6284, 7013], 'Smith': [920, 1925, 2652, 3816, 4825, 5552, 6286, 7015], '13964-13971Abstract': [927, 1932, 2659, 3823, 4832, 5559, 6293, 7022], '15Jennings': [934, 1939, 2666, 3830, 4839, 5566, 6300, 7029], 'Anderson': [936, 1941, 2668, 3832, 4841, 5568, 6302, 7031], 'M.P.': [937, 1561, 1942, 2669, 3833, 4459, 4842, 5569, 6303, 7032], '1987;': [941, 1946, 2673, 3837, 4846, 5573, 6307, 7036], '262:': [942, 1947, 2674, 3838, 4847, 5574, 6308, 7037], '1691-1697Abstract': [943, 1948, 2675, 3839, 4848, 5575, 6309, 7038], 'strong': [951, 3847], 'evidence': [952, 3848], 'implicate': [954, 3850], 'TM8': [956, 1145, 1163, 1187, 1654, 1717, 2138, 2161, 2307, 2719, 2817, 2836, 3079, 3129, 3852, 4042, 4060, 4084, 4553, 4616, 5038, 5061, 5207, 5619, 5717, 5736, 5979, 6029, 6500, 6523, 6670, 7082, 7181, 7200, 7445, 7495], 'residue,': [957, 3853], 'process,': [962, 3858], 'since': [963, 2277, 2959, 3859, 5177, 5859, 6639, 7324], 'labeling': [964, 3860], 'this': [965, 1377, 1533, 1756, 1857, 1885, 2212, 2273, 3157, 3309, 3861, 4275, 4431, 4655, 4757, 4785, 5112, 5173, 6057, 6209, 6218, 6246, 6574, 6635, 7523, 7675], 'residue': [966, 1150, 1956, 1979, 3862, 4047, 4856, 4879, 6317, 6340], "Woodward's": [968, 1066, 1899, 1970, 3864, 3962, 4799, 4870, 6260, 6331], 'reagent': [969, 1067, 1900, 1971, 3865, 3963, 4800, 4871, 6261, 6332], 'K': [970, 1068, 1972, 3866, 3964, 4872, 6333], 'reduction': [972, 3868], 'sodium': [974, 1491, 1580, 3870, 4389, 4478], 'borohydride': [975, 3871], 'resulted': [976, 3872], 'altered': [978, 3874], 'kinetics.': [981, 3877], 'functional': [983, 1679, 3879, 4578], 'role': [984, 1035, 3880, 3931], 'confirmed': [990, 3886], 'experiments': [993, 3889], '(16Chernova': [997, 3893], 'M.N.': [998, 3894], 'Jiang': [999, 3895], 'L.': [1000, 1620, 2582, 3896, 4518, 5482, 6945], 'Crest': [1001, 3897], 'Hand': [1003, 3899], 'Vandorpe': [1005, 3901], 'D.H.': [1006, 3902], 'Strange': [1007, 3903], '1997;': [1014, 1329, 1459, 3910, 4227, 4357], '109:': [1015, 1460, 3911, 4358], '345-360Crossref': [1016, 3912], '(81)': [1019, 3915], 'extended': [1023, 3919], 'homologous': [1026, 3922], 'position': [1027, 3923], 'AE2,': [1030, 3926], 'suggesting': [1031, 3927], 'mechanistic': [1034, 3930], 'among': [1040, 2776, 3936, 5676, 7140], 'proteins': [1043, 3939], '(17Sekler': [1044, 3940], 'I.': [1045, 3941], 'Lo': [1046, 3942], 'R.S.': [1047, 3943], '270:': [1054, 1690, 3950, 4589], '28751-28758Abstract': [1055, 3951], '(52)': [1063, 3959], 'chemical': [1069, 1196, 3965, 4093], 'modification': [1070, 1197, 3966, 4094], 'abolishes': [1073, 3969], 'transport,': [1075, 1988, 3971, 4888, 6349], 'yet': [1076, 3972], 'relieves': [1077, 3973], 'requirement': [1079, 3975], 'proton': [1081, 3977], 'cotransport': [1082, 1100, 3978, 3996], 'sulfate': [1084, 1087, 1987, 2631, 3980, 3983, 4887, 5531, 6348, 6994], 'During': [1086, 3982], 'unmodified': [1090, 3986], 'proton,': [1093, 3989], 'supplied': [1094, 3990], 'cotransported.': [1098, 3994], 'Sulfate/proton': [1099, 3995], 'takes': [1101, 3997], 'place': [1102, 3998], 'both': [1104, 1116, 3106, 3185, 3275, 4000, 4012, 6006, 6085, 6175, 7472, 7551, 7641], 'inward': [1105, 4001], 'outward': [1107, 3023, 4003, 5923, 7389], 'directions,': [1108, 4004], 'implies': [1110, 4006], 'access': [1114, 2287, 3269, 4010, 5187, 6169, 6649, 7635], 'extracellular': [1120, 3277, 4016, 6177, 7643], 'sides': [1121, 4017], 'Taken': [1125, 4021], 'together,': [1126, 4022], 'functionally': [1129, 4025], 'events': [1134, 4030], 'barrier': [1141, 3031, 4037, 5931, 7397], 'AE1.Glu681': [1143], 'best': [1148, 4045], 'characterized': [1149, 1674, 4046, 4573], 'event.': [1157, 4054], 'focused': [1161, 1883, 4058, 4783, 6244], 'on': [1162, 1838, 1884, 2105, 2621, 2685, 2731, 2784, 2801, 3233, 4059, 4737, 4784, 5005, 5521, 5585, 5631, 5684, 5701, 6133, 6245, 6467, 6984, 7048, 7094, 7148, 7165, 7599, 7701], 'efforts': [1165, 4062], 'translocation.': [1172, 2177, 4069, 5077, 6539], 'In': [1173, 1755, 2907, 3154, 4070, 4654, 5807, 6054, 6217, 7272, 7520], 'previous': [1175, 4072], 'report': [1176, 1757, 4073, 4656], 'analyzed': [1178, 4075], 'panel': [1180, 4077], 'spanning': [1185, 1208, 1728, 4082, 4105, 4627], 'Ser643': [1190, 4087], 'Ser690.': [1192, 4089], 'Using': [1193, 4090], 'accessibility': [1194, 4091], '3-(N-maleimidylpropionyl)biocytin': [1199, 4096], 'lucifer': [1201, 4098], 'yellow': [1202, 4099], 'iodoacetamide': [1203, 4100], 'bilayer': [1207, 1730, 4104, 4629], 'sequence': [1212, 1725, 1829, 1865, 2059, 3198, 4109, 4624, 4728, 4765, 4959, 6098, 6226, 6421, 7564], 'Met664–Gln683': [1213, 1726, 4110, 4625], '(18Tang': [1214, 1731, 2031, 3081, 4111, 4630, 4931, 5981, 6392, 7447], 'X.-B.': [1215, 1732, 2032, 3082, 4112, 4631, 4932, 5982, 6393, 7448], 'Fujinaga': [1216, 1733, 2033, 3083, 4113, 4632, 4933, 5983, 6394, 7449, 7697], '1998;': [1225, 1567, 1602, 1628, 1742, 2042, 2519, 3092, 4122, 4465, 4500, 4526, 4641, 4942, 5419, 5992, 6403, 6882, 7458], '273:': [1226, 1568, 1629, 1743, 2043, 3093, 4123, 4466, 4527, 4642, 4943, 5993, 6404, 7459], '22545-22553Abstract': [1227, 1744, 2044, 3094, 4124, 4643, 4944, 5994, 6405, 7460], '(92)': [1235, 1752, 2052, 3102, 4132, 4651, 4952, 6002, 6413, 7468], 'Scholar).Substituted': [1237], 'proved': [1244, 1380, 4142, 4278], 'fruitful': [1246, 4144], 'approach': [1247, 1292, 1378, 4145, 4190, 4276], 'pathway.': [1254, 4152], 'method': [1256, 4154], 'mutate': [1259, 4157], 'all': [1260, 4158], 'native': [1261, 4159], 'systematically': [1269, 1704, 4167, 4603], 're-introduce': [1270, 4168], 'unique': [1271, 4169], 'into': [1274, 1718, 2702, 2852, 4172, 4617, 5602, 5752, 7065, 7217], 'background.': [1277, 4175], 'Inhibition': [1278, 4176], 'then': [1286, 4184], 'mutant.': [1290, 4188], 'useful': [1295, 4193], 'studies': [1297, 2876, 4195, 5776, 7241], 'bacterial': [1300, 2487, 2914, 4198, 5387, 5814, 6850, 7279], 'proteins,': [1302, 1376, 4200, 4274], 'lactose': [1303, 4201], 'permease': [1304, 4202], '(19He': [1305, 4203], 'M.M.': [1306, 4204], 'Sun': [1307, 1322, 4205, 4220], '1996;': [1312, 1441, 1817, 2384, 2468, 2896, 2987, 3258, 4210, 4339, 4716, 5284, 5368, 5796, 5887, 6158, 6747, 6831, 7261, 7352, 7624], '35:': [1313, 1818, 3259, 4211, 4717, 6159, 7625], '12909-12914Crossref': [1314, 4212], '(35)': [1317, 4215], '20Frillingos': [1320, 4218], 'Gonzalez': [1324, 4222], '36:': [1330, 4228], '269-273Crossref': [1331, 4229], '(45)': [1334, 4232], '21Dunten': [1337, 4235], 'R.L.': [1338, 4236], 'Sahin-Tóth': [1339, 4237], 'R.H.': [1342, 4240], '32:': [1345, 4243], '12644-12650Crossref': [1346, 4244], '(60)': [1349, 4247], 'UhpT': [1353, 4251], '(22Yan': [1354, 2925, 4252, 5825, 7290], 'R.T.': [1355, 2926, 4253, 5826, 7291], 'Maloney': [1356, 2927, 4254, 5827, 7292], 'P.C.': [1357, 2928, 4255, 5828, 7293], '5973-5976Crossref': [1367, 2938, 4265, 5838, 7303], '(79)': [1370, 2941, 4268, 5841, 7306], 'Among': [1373, 4271], 'mammalian': [1374, 4272], 'very': [1381, 2607, 4279, 5507, 6970], 'successful': [1382, 4280], 'ion': [1384, 1395, 1403, 2493, 2554, 2602, 4282, 4293, 4301, 5393, 5454, 5502, 6856, 6917, 6965], 'channels.': [1385, 4283], 'Derivatization': [1386, 4284], 'methanethiosulfonate': [1392, 1540, 4290, 4438], 'will': [1393, 3230, 4291, 6130, 7596], 'impair': [1394, 4292], 'conductance': [1396, 4294], 'through': [1397, 1716, 2556, 4295, 4615, 5456, 6919], 'steric': [1398, 3117, 3173, 4296, 6017, 6073, 7483, 7539], 'blockage': [1399, 3118, 4297, 6018, 7484], 'confined': [1402, 4300], 'Pore-lining': [1406, 4304], 'channel,': [1413, 2356, 2881, 4311, 5256, 5781, 6719, 7246], 'CFTR': [1414, 2357, 2879, 2967, 4312, 5257, 5779, 5867, 6720, 7244, 7332], '(23Akabas': [1415, 2358, 4313, 5258, 6721], 'M.H.': [1416, 1438, 1455, 1475, 1494, 1510, 2359, 2381, 2403, 2423, 2893, 2984, 4314, 4336, 4353, 4373, 4392, 4408, 5259, 5281, 5303, 5323, 5793, 5884, 6722, 6744, 6766, 6786, 7258, 7349], 'Kaufmann': [1417, 1511, 2360, 2424, 4315, 4409, 5260, 5324, 6723, 6787], 'C.': [1418, 1512, 2361, 2425, 4316, 4410, 5261, 5325, 6724, 6788], 'Cook': [1419, 2362, 4317, 5262, 6725], 'T.A.': [1420, 2363, 4318, 5263, 6726], 'Archdeacon': [1421, 1513, 2364, 2426, 4319, 4411, 5264, 5326, 6727, 6789], 'P.': [1422, 1514, 2365, 2427, 2461, 4320, 4412, 5265, 5327, 5361, 6728, 6790, 6824], '269:': [1427, 2370, 4325, 5270, 6733], '14865-14868Abstract': [1428, 2371, 4326, 5271, 6734], '24Cheung': [1435, 2378, 4333, 5278, 6741], 'Akabas': [1437, 1454, 1474, 2380, 2402, 2892, 2983, 4335, 4352, 4372, 5280, 5302, 5792, 5883, 6743, 6765, 7257, 7348, 7687], 'Biophys.': [1439, 2382, 2894, 2985, 4337, 5282, 5794, 5885, 6745, 7259, 7350], '70:': [1442, 2385, 2897, 2988, 4340, 5285, 5797, 5888, 6748, 7262, 7353], '2688-2695Abstract': [1443, 2386, 2898, 2989, 4341, 5286, 5798, 5889, 6749, 7263, 7354], '(96)': [1449, 2392, 2904, 2995, 4347, 5292, 5804, 5895, 6755, 7269, 7360], '25Cheung': [1452, 4350], '289-299Crossref': [1461, 4359], '(85)': [1464, 4362], 'γ-aminobutyric': [1467, 2396, 4365, 5296, 6759], 'acid': [1468, 1864, 2397, 4366, 4764, 5297, 6225, 6760], 'receptor': [1469, 1490, 2398, 2419, 4367, 4388, 5298, 5319, 6761, 6782], 'channel': [1471, 1492, 2230, 2313, 2399, 2421, 2446, 2489, 2603, 2968, 4369, 4390, 5130, 5213, 5299, 5321, 5346, 5389, 5503, 5868, 6592, 6676, 6762, 6784, 6809, 6852, 6966, 7333], '(26Xu': [1472, 2400, 4370, 5300, 6763], '268:': [1480, 2408, 4378, 5308, 6771], '21505-21508Abstract': [1481, 2409, 4379, 5309, 6772], 'acetylcholine': [1489, 2418, 4387, 5318, 6781], '(27Akabas': [1493, 4391], 'Stauffer': [1495, 4393], 'D.A.': [1496, 1616, 2503, 4394, 4514, 5403, 6866], 'Xu': [1497, 1812, 3253, 4395, 4711, 6153, 7619], 'Karlin': [1499, 1515, 2428, 4397, 4413, 5328, 6791], 'Science.': [1501, 2518, 4399, 5418, 6881], '258:': [1503, 4401], '307-310Crossref': [1504, 4402], '(595)': [1507, 4405], 'Scholar,28Akabas': [1509, 4407], 'Neuron.': [1517, 2430, 4415, 5330, 6793], '13:': [1519, 2432, 4417, 5332, 6795], '919-927Abstract': [1520, 2433, 4418, 5333, 6796], '(356)': [1526, 2439, 4424, 5339, 6802], 'way.': [1534, 4432], 'Differential': [1535, 4433], 'sensitivity': [1536, 2947, 3189, 3288, 3307, 4434, 5847, 6089, 6188, 6207, 7312, 7555, 7654, 7673], 'inhibition': [1538, 1852, 4436, 4751], 'compounds': [1541, 4439], 'pathway': [1549, 2716, 2910, 4447, 5616, 5810, 7079, 7275], 'glutamate': [1552, 4450], 'GLT-1': [1555, 4453], '(29Zarbiv': [1556, 4454], 'Grunewald': [1558, 4456], 'Kavanaugh': [1560, 4458], 'Kanner': [1562, 4460], 'B.I.': [1563, 4461], '14231-14237Abstract': [1569, 4467], '(69)': [1577, 4475], 'glucose': [1581, 2915, 2960, 4479, 5815, 5860, 7280, 7325], 'cotransporter': [1582, 4480], '(30Loo': [1583, 4481], 'D.D.F.': [1584, 4482], 'Hirayama': [1585, 4483], 'B.A.': [1586, 4484], 'Gallardo': [1587, 4485], 'E.M.': [1588, 1594, 4486, 4492], 'Lam': [1589, 4487], 'J.T.': [1590, 4488], 'Turk': [1591, 4489], 'E.': [1592, 4490], 'Wright': [1593, 4491], '95:': [1603, 4501], '7789-7794Crossref': [1604, 4502], 'sodium/calcium': [1611, 4509], '(31Doering': [1613, 4511], 'Nicoll': [1615, 4513], 'Lu': [1617, 1619, 4515, 4517], 'Y.': [1618, 1683, 1811, 1813, 3252, 3254, 4516, 4582, 4710, 4712, 6152, 6154, 7618, 7620], 'Weiss': [1621, 4519], 'J.N.': [1622, 4520], 'Philipson': [1623, 4521], 'K.D.': [1624, 4522], '778-783Abstract': [1630, 4528], '(68)': [1638, 4536], 'Scholar).We': [1640], 'substituted': [1642, 4541], 'human': [1657, 1669, 1869, 2080, 4556, 4568, 4769, 4980, 6230, 6442], 'Previously': [1662, 4561], 'constructed': [1664, 4563], 'fully': [1678, 2921, 4577, 5821, 7286], '(32Casey': [1680, 4579], 'Ding': [1682, 4581], '8521-8527Abstract': [1691, 4590], '(54)': [1699, 4598], 'replaced': [1705, 4604], 'glycosylation': [1712, 4611], 'site': [1713, 2774, 3070, 3215, 3310, 4612, 5674, 5970, 6115, 6210, 7138, 7436, 7581, 7676], 'Asn642': [1715, 4614], 'measure': [1759, 4658], 'effect': [1761, 4660], 'upon': [1766, 4665], 'function,': [1770, 4669], 'using': [1771, 4670], 'BCECF': [1772, 4671], 'fluorescence': [1773, 4672], 'monitor': [1775, 4674], 'pH': [1777, 4676], 'shifts': [1778, 4677], 'associated': [1779, 4678], 'transfected': [1784, 4683], 'Of': [1787, 4686], 'reagents,': [1791, 4690], 'pCMBS': [1792, 1854, 2091, 2289, 2882, 2924, 2949, 3107, 3188, 3221, 3290, 4691, 4753, 4991, 5189, 5782, 5824, 5849, 6007, 6088, 6121, 6190, 6453, 6651, 7247, 7289, 7314, 7473, 7554, 7587, 7656], 'membrane-impermeant': [1794, 4693], 'but': [1795, 2605, 2725, 3167, 4694, 5505, 5625, 6067, 6968, 7088, 7533], 'slowly': [1796, 4695], 'transported': [1797, 4696], 'while': [1800, 2790, 4699, 5690, 7154], 'MTSEA': [1801, 3109, 3241, 4700, 6009, 6141, 7475, 7607], 'membrane-permeant': [1803, 4702], 'its': [1805, 2699, 3246, 4704, 5599, 6146, 7062, 7612], 'unprotonated': [1806, 4705], '(33Holmgren': [1808, 3249, 4707, 6149, 7615], 'Liu': [1810, 3251, 4709, 6151, 7617], 'Yellen': [1814, 3255, 4713, 6155, 7621], 'Neuropharmacology.': [1816, 3257, 4715, 6157, 7623], '797-804Crossref': [1819, 3260, 4718, 6160, 7626], '(191)': [1822, 3263, 4721, 6163, 7629], 'leucine,': [1831, 2301, 4730, 5201, 6664], 'alanine': [1834, 2304, 4733, 5204, 6667], 'lie': [1837, 4736], 'α-helix': [1843, 4742], 'and,': [1844, 4743], 'when': [1845, 4744], 'mutated': [1846, 4745], 'cysteine,': [1848, 4747], 'susceptible': [1850, 4749], 'MTSEA.DISCUSSIONIn': [1856], 'paper': [1858, 4758, 6219], 'examined': [1861, 4761, 6222], 'amino': [1863, 2299, 2324, 2500, 4763, 5199, 5224, 5400, 6224, 6662, 6687, 6863], 'SER643–SER690': [1867, 4767, 6228], 'line': [1875, 2199, 2226, 2305, 2335, 2830, 3155, 4775, 5099, 5126, 5205, 5235, 5730, 6055, 6236, 6561, 6588, 6668, 6698, 7194, 7521], 'because': [1887, 2627, 4787, 5527, 6248, 6990], 'it': [1888, 3229, 4788, 6129, 6249, 7595], 'contains': [1889, 4789, 6250], 'shown': [1891, 2169, 4791, 5069, 6252, 6531], 'previously': [1892, 2170, 4792, 5070, 6253, 6532], 'accessible': [1895, 1968, 4795, 4868, 6256, 6329], 'impermeant': [1898, 4798, 6259], 'K,': [1901, 4801, 6262], 'either': [1903, 2086, 4803, 4986, 6264, 6448], 'side': [1904, 2320, 2700, 4804, 5220, 5600, 6265, 6683, 7063], 'This': [1955, 2769, 2819, 2944, 4855, 5669, 5719, 5844, 6316, 7133, 7183, 7309], 'Because': [1965, 4865, 6326], 'anions,': [1983, 4883, 6344], 'decided': [1990, 4890, 6351], 'examine': [1992, 4892, 6353], 'surrounding': [1995, 4895, 6356], 'find': [1998, 4898, 6359], 'other': [1999, 2765, 2781, 4899, 5665, 5681, 6360, 7129, 7145], 'channel.': [2007, 2338, 4907, 5238, 6368, 6701], 'recently': [2009, 4909, 6370], 'determined': [2010, 4910, 6371], 'topology': [2012, 4912, 6373], 'localized': [2018, 4918, 6379], 'within': [2021, 2132, 4921, 5032, 6382, 6494], 'four': [2022, 4922, 6383], 'cytosolic': [2026, 3235, 4926, 6135, 6387, 7601], 'surface': [2027, 2120, 2253, 2539, 3236, 4927, 5020, 5153, 5439, 6136, 6388, 6482, 6615, 6902, 7602], 'Scholar).Our': [2054, 4954], 'results': [2055, 2848, 4955, 5748, 6417, 7213], '(Ala666,': [2064, 4964, 6426], 'Ser667,': [2065, 2218, 4965, 5118, 6427, 6580], 'Leu669,': [2066, 2219, 4966, 5119, 6428, 6581], 'Leu673,': [2067, 2220, 4967, 5120, 6429, 6582], 'Leu677,': [2068, 2221, 4968, 5121, 6430, 6583], 'Leu680,': [2069, 2222, 3204, 4969, 5122, 6104, 6431, 6584, 7570], 'Ile684,': [2070, 2223, 4970, 5123, 6432, 6585], 'Ile688)': [2072, 4972, 6434], 'can': [2083, 3222, 3268, 4983, 6122, 6168, 6445, 7588, 7634], 'or': [2092, 4992, 6454], 'MTSEA.': [2093, 4755, 4993, 6455], 'locations': [2095, 4995, 6457], 'periodicity': [2102, 5002, 6464], 'predicted': [2110, 2728, 5010, 5628, 6472, 7091], 'α-helix,': [2111, 5011, 6473], 'turn': [2117, 5017, 6479], 'Seven': [2124, 5024, 6486], 'eight': [2127, 5027, 6489], 'found': [2131, 2344, 3160, 3195, 3292, 5031, 5244, 6060, 6095, 6192, 6493, 6707, 7526, 7561, 7658], '100°': [2134, 5034, 6496], 'arc': [2135, 5035, 6497], 'plot,': [2141, 5041, 6503], 'indicating': [2142, 5042, 6504], 'forms': [2146, 3021, 5046, 5921, 6508, 7387], 'α-helix.': [2148, 5048, 6510], 'sensitive': [2150, 3132, 3164, 3183, 5050, 6032, 6064, 6083, 6512, 7498, 7530, 7549], 'opposite': [2155, 5055, 6517], 'adjacent': [2164, 3298, 5064, 6198, 6526, 7664], 'interact': [2172, 2232, 5072, 5132, 6534, 6594], 'simplest': [2179, 5079, 6541], 'explanation': [2180, 5080, 6542], 'our': [2182, 2692, 3282, 5082, 5592, 6182, 6544, 7055, 7648], 'covalent': [2186, 5086, 6548], 'interaction': [2187, 5087, 6549], 'compounds;': [2195, 5095, 6557], 'sites': [2197, 2782, 5097, 5682, 6559, 7146], 'these': [2202, 2323, 5102, 5223, 6564, 6686], 'block': [2204, 5104, 6566], 'pore': [2206, 2495, 2550, 2567, 2690, 2736, 2974, 3020, 3149, 3273, 3315, 5106, 5395, 5450, 5467, 5590, 5636, 5874, 5920, 6049, 6173, 6215, 6568, 6858, 6913, 6930, 7053, 7099, 7339, 7386, 7515, 7639, 7681], 'propose': [2215, 5115, 6577], 'Ala666,': [2217, 5117, 6579], 'Ile688': [2225, 5125, 6587], 'they': [2237, 5137, 6599], 'cross': [2238, 5138, 6600], 'bilayer.': [2240, 5140, 6602], 'An': [2241, 5141, 6603], 'alternate': [2242, 5142, 6604], 'possibility': [2243, 5143, 6605], 'conformationally': [2251, 5151, 6613], 'active': [2252, 5152, 6614], 'cleft': [2259, 2280, 5159, 5180, 6621, 6642], 'where': [2260, 5160, 6622], 'helices': [2262, 5162, 6624], 'meet': [2263, 5163, 6625], 'whose': [2265, 5165, 6627], 'movements': [2266, 5166, 6628], 'blocked': [2268, 5168, 6630], 'modification.': [2271, 5171, 6633], 'However,': [2272, 2339, 2682, 5172, 5239, 5582, 6634, 6702, 7045], 'unlikely': [2276, 5176, 6638], 'would': [2281, 2551, 2820, 5181, 5451, 5720, 6643, 6914, 7184], 'not': [2282, 2327, 2619, 2844, 3168, 3231, 5182, 5227, 5519, 5744, 6068, 6131, 6644, 6690, 6982, 7208, 7534, 7597], 'likely': [2284, 5184, 6646], 'hydrophilic': [2293, 2328, 2773, 5193, 5228, 5673, 6655, 6691, 7137], 'reagents.Our': [2294, 5194], 'observation': [2295, 2610, 3123, 5195, 5510, 6023, 6658, 6973, 7489], 'acids': [2300, 2325, 2501, 5200, 5225, 5401, 6663, 6688, 6864], 'portion': [2308, 3127, 5208, 6027, 6671, 7493], 'first': [2315, 3067, 5215, 5967, 6678, 7433], 'seems': [2316, 5216, 6679], 'surprising.': [2317, 5217, 6680], 'alkyl': [2319, 5219, 6682], 'chains': [2321, 5221, 6684], 'cannot': [2330, 5230, 6693], 'contribute': [2331, 5231, 6694], 'hydrogen': [2332, 5232, 6695], 'bonds': [2333, 5233, 6696], 'lining': [2350, 2533, 2561, 5250, 5433, 5461, 6713, 6896, 6924], 'Na+': [2420, 5320, 6783], '(28Akabas': [2422, 5322, 6785], 'carbohydrate': [2444, 5344, 6807], 'maltoporin': [2449, 5349, 6812], 'lined': [2452, 2497, 5352, 5397, 6815, 6860], '(44Dutzler': [2456, 5356, 6819], 'Wang': [2458, 5358, 6821], 'Y.F.': [2459, 5359, 6822], 'Rizkallah': [2460, 5360, 6823], 'Rosenbusch': [2462, 5362, 6825], 'J.P.': [2463, 5363, 6826], 'Schirmer': [2464, 5364, 6827], 'Structure': [2466, 5366, 6829], '(Lond.).': [2467, 5367, 6830], '4:': [2469, 5369, 6832], '127-134Abstract': [2470, 5370, 6833], '(154)': [2478, 5378, 6841], 'Similarly,': [2481, 2874, 5381, 5774, 6844, 7239], 'crystal': [2483, 5383, 6846], 'K+': [2488, 5388, 6851], 'illustrated': [2490, 5390, 6853], '(45Doyle': [2502, 5402, 6865], 'Cabral': [2504, 5404, 6867], 'J.M.': [2505, 2511, 5405, 5411, 6868, 6874], 'Pfuetzner': [2506, 5406, 6869], 'R.A.': [2507, 5407, 6870], 'Kuo': [2508, 5408, 6871], 'Gulbis': [2510, 5410, 6873], 'Cohen': [2512, 5412, 6875], 'Chait': [2514, 5414, 6877], 'B.T.': [2515, 5415, 6878], 'MacKinnon': [2516, 5416, 6879], '280:': [2520, 5420, 6883], '69-77Crossref': [2521, 5421, 6884], '(5686)': [2524, 5424, 6887], 'authors': [2528, 5428, 6891], 'speculated': [2529, 5429, 6892], 'provides': [2534, 2999, 5434, 5899, 6897, 7364], 'energetically': [2537, 5437, 6900], 'favorable': [2538, 5438, 6901], 'ions.': [2543, 5443, 6906], 'Interactions': [2544, 5444, 6907], 'wall': [2547, 5447, 6910], 'only': [2552, 2772, 2868, 2884, 3226, 5452, 5672, 5768, 5784, 6126, 6915, 7136, 7233, 7249, 7592], 'impede': [2553, 5453, 6916], 'transit': [2555, 5455, 6918], 'A': [2559, 5459, 6922], 'important': [2570, 5470, 6933], 'facilitate': [2572, 5472, 6935], 'turnover': [2575, 5475, 6938], 'rate': [2576, 5476, 6939], '(105': [2577, 5477, 6940], 'anions·s−1': [2578, 5478, 6941], '(46Jay': [2579, 5479, 6942], 'Cantley': [2581, 5481, 6944], 'Annu.': [2583, 5483, 6946], '1986;': [2586, 5486, 6949], '55:': [2587, 5487, 6950], '511-538Crossref': [2588, 5488, 6951], '(110)': [2591, 5491, 6954], 'Scholar)),': [2593, 5493, 6956], 'order': [2597, 5497, 6960], 'magnitude': [2599, 5499, 6962], 'slower': [2600, 5500, 6963], 'than': [2601, 2964, 3136, 3190, 5501, 5864, 6036, 6090, 6964, 7329, 7502, 7556], 'fluxes,': [2604, 5504, 6967], 'still': [2606, 5506, 6969], 'fast.': [2608, 5508, 6971], 'centered': [2620, 5520, 6983], 'seem': [2625, 5525, 6988], 'surprising,': [2626, 5526, 6989], 'edge': [2687, 2733, 5587, 5633, 7050, 7096], '(Fig.': [2694, 5594, 7057], '6)': [2695, 5595, 7058], 'extend': [2698, 5598, 7061], 'chain': [2701, 5601, 7064], 'Interestingly,': [2705, 5605, 7068], 'presented': [2708, 5608, 7071], 'TM9': [2722, 5622, 7085], 'TM10,': [2724, 5624, 7087], 'E681': [2726, 5626, 7089], 'Scholar).Mutant': [2759, 5659], 'S667C': [2760, 2791, 2806, 5660, 5691, 5706, 7124, 7155, 7170], 'stands': [2761, 5661, 7125], 'apart': [2762, 5662, 7126], 'reagent-sensitive': [2767, 3069, 5667, 5969, 7131, 7435], 'sites.': [2768, 5668, 7132], 'observed': [2775, 2861, 5675, 5761, 7139, 7226], 'residues.': [2779, 5679, 7143], 'cluster': [2783, 5683, 7147], 'helix,': [2789, 5689, 7153], '60°': [2793, 5693, 7157], 'removed': [2794, 5694, 7158], 'rest': [2797, 5697, 7161], 'mutants,': [2800, 3184, 5700, 6084, 7164, 7550], 'Pro670,': [2810, 5710, 7174], 'kink': [2813, 5713, 7177], 'twist': [2815, 5715, 7179], 'helix.': [2818, 5718, 7182], 'result': [2821, 5721, 7185], 'exposure': [2823, 5723, 7187], 'discontinuous': [2826, 5726, 7190], 'That': [2833, 5733, 7197], 'above': [2839, 5739, 7203], 'below': [2841, 5741, 7205], 'Pro680': [2842, 5742, 7206], 'aligned.Our': [2847, 5747], 'provide': [2850, 3060, 5750, 5960, 7215, 7426], 'insight': [2851, 5751, 7216], 'partially': [2869, 5769, 7234], '(<40%)': [2870, 5770, 7235], 'pCMBS.': [2873, 3176, 5773, 6076, 7238, 7542], 'able': [2885, 5785, 7250], '25–75%': [2889, 5789, 7254], '(24Cheung': [2890, 2981, 5790, 5881, 7255, 7346], 'contrast': [2908, 5808, 7273], '6-phosphate': [2916, 2961, 5816, 5861, 7281, 7326], 'transporter,': [2917, 5817, 7282], 'UhpT,': [2918, 5818, 7283], 'nearly': [2920, 5820, 7285], 'difference': [2945, 5845, 7310], 'reflect': [2951, 3312, 5851, 6212, 7316, 7678], 'size': [2953, 3006, 5853, 5906, 7318, 7371], 'larger': [2963, 3172, 5863, 6072, 7328, 7538], 'chloride.': [2965, 5865, 7330], 'estimated': [2970, 5870, 7335], 'diameter': [2975, 5875, 7340], '6': [2979, 5879, 7344], 'Å': [2980, 5880, 7345], 'approximation': [3003, 5903, 7368], 'pore.One': [3010, 5910], 'prevailing': [3011, 5911, 7377], 'facing': [3024, 5924, 7390], 'funnel': [3025, 5925, 7391], 'narrows': [3027, 5927, 7393], '(47Jennings': [3034, 5934, 7400], 'Hamasaki': [3036, 5936, 7402], 'N.': [3037, 5937, 7403], 'Protein': [3042, 5942, 7408], 'Red': [3045, 5945, 7411], 'Blood': [3046, 5946, 7412], 'Cell': [3047, 5947, 7413], 'Membrane.': [3048, 5948, 7414], 'Publishers': [3051, 5951, 7417], 'V.,': [3053, 5953, 7419], 'Amsterdam1989:': [3054, 5954, 7420], '59-72Google': [3055, 5955, 7421], 'support': [3062, 5962, 7428], 'model.': [3065, 5965, 7431], '(Ala666)': [3071, 5971, 7437], 'located': [3073, 5973, 7439], 'start': [3076, 5976, 7442], '(Met664)': [3080, 5980, 7446], 'Since': [3105, 3220, 6005, 6120, 7471, 7586], 'expected': [3111, 6011, 7477], 'inner': [3126, 3152, 3192, 6026, 6052, 6092, 7492, 7518, 7558], 'more': [3131, 3141, 3147, 6031, 6041, 6047, 7497, 7507, 7513], 'outer': [3138, 3143, 6038, 6043, 7504, 7509], 'open': [3142, 6042, 7508], 'closed': [3148, 6048, 7514], 'region.': [3153, 6053, 7519], 'model,': [3158, 6058, 7524], 'L669C': [3162, 6062, 7528], 'reflecting': [3170, 6070, 7536], 'bulk': [3174, 6074, 7540], 'Furthermore,': [3177, 6077, 7543], 'A666C': [3178, 6078, 7544], 'outermost': [3182, 6082, 7548], 'had': [3186, 6086, 7552], 'lower': [3187, 6087, 7553], 'mutants.': [3193, 6093, 7559], 'pCMBS-inhibited': [3200, 6100, 7566], 'ended': [3202, 6102, 7568], 'consistent': [3207, 6107, 7573], 'identification': [3210, 6110, 7576], 'permeate': [3223, 6123, 7589], 'via': [3227, 6127, 7593], 'accumulate': [3232, 6132, 7598], 'any': [3238, 6138, 7604], 'extent.': [3239, 6139, 7605], 'Conversely,': [3240, 6140, 7606], 'permeant': [3244, 6144, 7610], 'deprotonated': [3247, 6147, 7613], 'surfaces.': [3280, 6180, 7646], 'Finally,': [3281, 6181, 7647], 'show': [3284, 6184, 7650], 'greatest': [3287, 6187, 7653], 'L680C,': [3295, 6195, 7661], 'presumed': [3302, 6202, 7668], 'smaller': [3314, 6214, 7680], 'diameter.': [3316, 6216, 7682], 'Several': [3662], 'Substituted': [4135], 'DISCUSSIONIn': [4756], 'reagents.': [6656], 'Mutant': [7123], 'aligned.': [7211], 'One': [7376], 'thank': [7684], 'Dr.': [7685, 7691, 7695], 'Myles': [7686], 'helpful': [7689, 7699], 'advice.': [7690], 'Andrew': [7692], 'Taylor': [7693], 'Jocelyne': [7696], 'provided': [7698], 'comments': [7700], 'manuscript.': [7703]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2023755723', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-12T11:01:17.725212', 'created_date': '2016-06-24'}