Publication Information

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'farnesylated': [20], 'prelamin': [21, 59, 81, 96], 'A': [22, 60, 97, 104], 'variant': [23], 'called': [24], 'progerin.': [25], 'The': [26], 'accumulation': [27], 'progerin': [29], 'at': [30], 'nuclear': [32, 63, 90, 102, 112], 'envelope': [33], 'causes': [34], 'mis-shapen': [35], 'nuclei': [36], 'and': [37, 93, 108, 138], 'results': [38], 'progeroid': [40, 136], 'syndromes.': [41], 'Previous': [42], 'studies': [43], 'cells': [45], 'from': [46, 99, 118], 'individuals': [47], 'with': [48, 146], 'have': [52], 'shown': [53], 'blocking': [55], 'farnesylation': [57, 79], 'ameliorates': [61], 'shape': [64, 91, 113], 'abnormalities.': [65], 'Here': [66], 'we': [67], 'observed': [68], 'an': [70], 'inhibitor': [71], 'farnesyl': [73], 'diphosphate': [74], 'synthase,': [75], 'N6-isopentenyladenosine,': [76], 'impeded': [77], 'A,': [82], 'causing': [83], 'decrease': [85], 'frequency': [88], 'abnormalities': [92], 'redistribution': [94], 'away': [98], 'inner': [101], 'envelope.': [103], 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'updated_date': '2024-12-09T08:20:29.852007', 'created_date': '2016-06-24'}