Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2022871996', 'doi': 'https://doi.org/10.1097/00004850-200405000-00001', 'title': 'A review of acute treatments for bipolar depression', 'display_name': 'A review of acute treatments for bipolar depression', 'publication_year': 2004, 'publication_date': '2004-05-01', 'ids': {'openalex': 'https://openalex.org/W2022871996', 'doi': 'https://doi.org/10.1097/00004850-200405000-00001', 'mag': '2022871996', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15107653'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00004850-200405000-00001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S149156103', 'display_name': 'International Clinical Psychopharmacology', 'issn_l': '0268-1315', 'issn': ['0268-1315', '1473-5857'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310318547', 'host_organization_name': 'Wolters Kluwer', 'host_organization_lineage': ['https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019721873', 'display_name': 'Peter H. Silverstone', 'orcid': 'https://orcid.org/0000-0001-5176-7074'}, 'institutions': [{'id': 'https://openalex.org/I154425047', 'display_name': 'University of Alberta', 'ror': 'https://ror.org/0160cpw27', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I154425047']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Peter H. Silverstone', 'raw_affiliation_strings': ['Departments of Psychiatry and Neuroscience, University of Alberta, Edmonton, Alberta, Canada. [email protected]'], 'affiliations': [{'raw_affiliation_string': 'Departments of Psychiatry and Neuroscience, University of Alberta, Edmonton, Alberta, Canada. [email protected]', 'institution_ids': ['https://openalex.org/I154425047']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007825498', 'display_name': 'Trevor Silverstone', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Trevor Silverstone', 'raw_affiliation_strings': [], 'affiliations': []}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.465, 'has_fulltext': False, 'cited_by_count': 50, 'citation_normalized_percentile': {'value': 0.4808, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '19', 'issue': '3', 'first_page': '113', 'last_page': '124'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10854', 'display_name': 'Epidemiology and Management of Bipolar Disorder', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10854', 'display_name': 'Epidemiology and Management of Bipolar Disorder', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11921', 'display_name': 'Efficacy and Safety of Electroconvulsive Therapy', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12229', 'display_name': 'Prenatal Exposure to Antiepileptic Drugs', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mood-stabilizer', 'display_name': 'Mood stabilizer', 'score': 0.66351056}, {'id': 'https://openalex.org/keywords/bupropion', 'display_name': 'Bupropion', 'score': 0.6584829}, {'id': 'https://openalex.org/keywords/depression', 'display_name': 'Depression', 'score': 0.536034}, {'id': 'https://openalex.org/keywords/divalproex', 'display_name': 'Divalproex', 'score': 0.46298707}], 'concepts': [{'id': 'https://openalex.org/C2778802184', 'wikidata': 'https://www.wikidata.org/wiki/Q410346', 'display_name': 'Lamotrigine', 'level': 3, 'score': 0.88489366}, {'id': 'https://openalex.org/C2776174506', 'wikidata': 'https://www.wikidata.org/wiki/Q131755', 'display_name': 'Bipolar disorder', 'level': 3, 'score': 0.72297835}, {'id': 'https://openalex.org/C2780550438', 'wikidata': 'https://www.wikidata.org/wiki/Q2622367', 'display_name': 'Mood stabilizer', 'level': 4, 'score': 0.66351056}, {'id': 'https://openalex.org/C2779908668', 'wikidata': 'https://www.wikidata.org/wiki/Q834280', 'display_name': 'Bupropion', 'level': 3, 'score': 0.6584829}, {'id': 'https://openalex.org/C2778541603', 'wikidata': 'https://www.wikidata.org/wiki/Q152763', 'display_name': 'Lithium (medication)', 'level': 2, 'score': 0.630612}, {'id': 'https://openalex.org/C2779177272', 'wikidata': 'https://www.wikidata.org/wiki/Q76560', 'display_name': 'Antidepressant', 'level': 3, 'score': 0.5683744}, {'id': 'https://openalex.org/C2779253243', 'wikidata': 'https://www.wikidata.org/wiki/Q410412', 'display_name': 'Carbamazepine', 'level': 3, 'score': 0.5607371}, {'id': 'https://openalex.org/C2776619155', 'wikidata': 'https://www.wikidata.org/wiki/Q201872', 'display_name': 'Olanzapine', 'level': 3, 'score': 0.54378873}, {'id': 'https://openalex.org/C2777330709', 'wikidata': 'https://www.wikidata.org/wiki/Q131543', 'display_name': 'Electroconvulsive therapy', 'level': 3, 'score': 0.53611606}, {'id': 'https://openalex.org/C2776809841', 'wikidata': 'https://www.wikidata.org/wiki/Q185935', 'display_name': 'Mania', 'level': 4, 'score': 0.5169305}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.5051523}, {'id': 'https://openalex.org/C2780634440', 'wikidata': 'https://www.wikidata.org/wiki/Q408535', 'display_name': 'Quetiapine', 'level': 3, 'score': 0.49879122}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.47211397}, {'id': 'https://openalex.org/C2908949014', 'wikidata': 'https://www.wikidata.org/wiki/Q240642', 'display_name': 'Divalproex', 'level': 5, 'score': 0.46298707}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.43911496}, {'id': 'https://openalex.org/C2776921671', 'wikidata': 'https://www.wikidata.org/wiki/Q758295', 'display_name': 'Atypical antipsychotic', 'level': 4, 'score': 0.42054614}, {'id': 'https://openalex.org/C2780494398', 'wikidata': 'https://www.wikidata.org/wiki/Q208144', 'display_name': 'Antipsychotic', 'level': 3, 'score': 0.41903514}, {'id': 'https://openalex.org/C2778186239', 'wikidata': 'https://www.wikidata.org/wiki/Q41571', 'display_name': 'Epilepsy', 'level': 2, 'score': 0.20210144}, {'id': 'https://openalex.org/C2776412080', 'wikidata': 'https://www.wikidata.org/wiki/Q7431605', 'display_name': 'Schizophrenia (object-oriented programming)', 'level': 2, 'score': 0.19696766}, {'id': 'https://openalex.org/C558461103', 'wikidata': 'https://www.wikidata.org/wiki/Q154430', 'display_name': 'Anxiety', 'level': 2, 'score': 0.09988424}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C2777843972', 'wikidata': 'https://www.wikidata.org/wiki/Q2462253', 'display_name': 'Smoking cessation', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001714', 'descriptor_name': 'Bipolar Disorder', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000927', 'descriptor_name': 'Anticonvulsants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000928', 'descriptor_name': 'Antidepressive Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000928', 'descriptor_name': 'Antidepressive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001569', 'descriptor_name': 'Benzodiazepines', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D001569', 'descriptor_name': 'Benzodiazepines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001714', 'descriptor_name': 'Bipolar Disorder', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D001714', 'descriptor_name': 'Bipolar Disorder', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018491', 'descriptor_name': 'Dopamine Agonists', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D018491', 'descriptor_name': 'Dopamine Agonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004565', 'descriptor_name': 'Electroconvulsive Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018020', 'descriptor_name': 'Lithium Compounds', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D018020', 'descriptor_name': 'Lithium Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012892', 'descriptor_name': 'Sleep Deprivation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/00004850-200405000-00001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S149156103', 'display_name': 'International Clinical Psychopharmacology', 'issn_l': '0268-1315', 'issn': ['0268-1315', '1473-5857'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310318547', 'host_organization_name': 'Wolters Kluwer', 'host_organization_lineage': ['https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15107653', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.85, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 189, 'referenced_works': ['https://openalex.org/W105987577', 'https://openalex.org/W117890930', 'https://openalex.org/W122815215', 'https://openalex.org/W137284767', 'https://openalex.org/W148226213', 'https://openalex.org/W1490135084', 'https://openalex.org/W1534112212', 'https://openalex.org/W1561543846', 'https://openalex.org/W1563652268', 'https://openalex.org/W1580914753', 'https://openalex.org/W160067425', 'https://openalex.org/W16007235', 'https://openalex.org/W1623346414', 'https://openalex.org/W168796211', 'https://openalex.org/W171967332', 'https://openalex.org/W173265093', 'https://openalex.org/W1764919821', 'https://openalex.org/W1890987751', 'https://openalex.org/W1930195718', 'https://openalex.org/W1964735383', 'https://openalex.org/W1965021757', 'https://openalex.org/W1965480477', 'https://openalex.org/W1965632145', 'https://openalex.org/W1965941677', 'https://openalex.org/W1966000037', 'https://openalex.org/W1972677128', 'https://openalex.org/W1973339853', 'https://openalex.org/W1974183999', 'https://openalex.org/W1976130667', 'https://openalex.org/W1980181121', 'https://openalex.org/W1981207331', 'https://openalex.org/W1981234468', 'https://openalex.org/W1982377327', 'https://openalex.org/W1983626572', 'https://openalex.org/W1984395863', 'https://openalex.org/W1985086901', 'https://openalex.org/W1993284855', 'https://openalex.org/W1993494277', 'https://openalex.org/W1994070887', 'https://openalex.org/W1994141304', 'https://openalex.org/W1994510319', 'https://openalex.org/W1994759548', 'https://openalex.org/W1996352074', 'https://openalex.org/W1998085422', 'https://openalex.org/W1999389597', 'https://openalex.org/W1999488122', 'https://openalex.org/W2003629147', 'https://openalex.org/W2008000852', 'https://openalex.org/W2008923408', 'https://openalex.org/W2011347417', 'https://openalex.org/W2011665759', 'https://openalex.org/W2015919652', 'https://openalex.org/W2016999205', 'https://openalex.org/W2018445669', 'https://openalex.org/W2019393379', 'https://openalex.org/W2021627893', 'https://openalex.org/W2023228200', 'https://openalex.org/W2023319347', 'https://openalex.org/W2023768937', 'https://openalex.org/W2023879908', 'https://openalex.org/W2024700133', 'https://openalex.org/W2025915637', 'https://openalex.org/W2028468262', 'https://openalex.org/W2029639141', 'https://openalex.org/W2029738937', 'https://openalex.org/W2031358990', 'https://openalex.org/W2034283258', 'https://openalex.org/W2034718172', 'https://openalex.org/W2035713462', 'https://openalex.org/W2035886212', 'https://openalex.org/W2036072463', 'https://openalex.org/W2037182446', 'https://openalex.org/W2037231243', 'https://openalex.org/W2039222880', 'https://openalex.org/W2041409401', 'https://openalex.org/W2044567703', 'https://openalex.org/W2046089270', 'https://openalex.org/W2048002593', 'https://openalex.org/W2048511631', 'https://openalex.org/W2048549144', 'https://openalex.org/W2049031623', 'https://openalex.org/W2052024880', 'https://openalex.org/W2052992892', 'https://openalex.org/W2054835817', 'https://openalex.org/W2056270749', 'https://openalex.org/W2057170051', 'https://openalex.org/W2057822023', 'https://openalex.org/W2058120764', 'https://openalex.org/W2058432935', 'https://openalex.org/W2058662910', 'https://openalex.org/W2059975487', 'https://openalex.org/W2061070907', 'https://openalex.org/W2062696434', 'https://openalex.org/W2063347068', 'https://openalex.org/W2064288410', 'https://openalex.org/W2064478935', 'https://openalex.org/W2065648976', 'https://openalex.org/W2066364574', 'https://openalex.org/W2066627514', 'https://openalex.org/W2068173411', 'https://openalex.org/W2068508452', 'https://openalex.org/W2070238765', 'https://openalex.org/W2070861572', 'https://openalex.org/W2073585956', 'https://openalex.org/W2073740255', 'https://openalex.org/W2074142296', 'https://openalex.org/W2076717931', 'https://openalex.org/W2077648424', 'https://openalex.org/W2078611955', 'https://openalex.org/W2080984453', 'https://openalex.org/W2081125298', 'https://openalex.org/W2084151035', 'https://openalex.org/W2084686735', 'https://openalex.org/W2085589409', 'https://openalex.org/W2085665483', 'https://openalex.org/W2086878753', 'https://openalex.org/W2089401246', 'https://openalex.org/W2089904748', 'https://openalex.org/W2090339413', 'https://openalex.org/W2090382442', 'https://openalex.org/W2090392055', 'https://openalex.org/W2095055072', 'https://openalex.org/W2099789765', 'https://openalex.org/W2102460856', 'https://openalex.org/W2104719459', 'https://openalex.org/W2107231683', 'https://openalex.org/W2108061350', 'https://openalex.org/W2109442247', 'https://openalex.org/W2109620132', 'https://openalex.org/W2110200618', 'https://openalex.org/W2112503260', 'https://openalex.org/W2112505980', 'https://openalex.org/W2113580630', 'https://openalex.org/W2115147704', 'https://openalex.org/W2118696790', 'https://openalex.org/W2120383646', 'https://openalex.org/W2121339106', 'https://openalex.org/W2123791787', 'https://openalex.org/W2124907633', 'https://openalex.org/W2124969157', 'https://openalex.org/W2125595726', 'https://openalex.org/W2126464268', 'https://openalex.org/W2126891996', 'https://openalex.org/W2127942376', 'https://openalex.org/W2128478444', 'https://openalex.org/W2130040176', 'https://openalex.org/W2131214108', 'https://openalex.org/W2136947532', 'https://openalex.org/W2142644082', 'https://openalex.org/W2147420992', 'https://openalex.org/W2148756669', 'https://openalex.org/W2154790483', 'https://openalex.org/W2156492694', 'https://openalex.org/W2159163640', 'https://openalex.org/W2159498454', 'https://openalex.org/W2161480846', 'https://openalex.org/W2164399469', 'https://openalex.org/W2171118650', 'https://openalex.org/W2291547218', 'https://openalex.org/W2317383367', 'https://openalex.org/W2327976943', 'https://openalex.org/W2329661970', 'https://openalex.org/W2345733617', 'https://openalex.org/W2386118537', 'https://openalex.org/W2400656446', 'https://openalex.org/W2405219202', 'https://openalex.org/W2409172845', 'https://openalex.org/W2409500620', 'https://openalex.org/W2409762864', 'https://openalex.org/W2412344197', 'https://openalex.org/W2413578938', 'https://openalex.org/W2419618723', 'https://openalex.org/W2422903526', 'https://openalex.org/W2424959181', 'https://openalex.org/W2436809137', 'https://openalex.org/W2466972082', 'https://openalex.org/W2775781581', 'https://openalex.org/W3185308597', 'https://openalex.org/W4210965604', 'https://openalex.org/W4237794358', 'https://openalex.org/W4248277343', 'https://openalex.org/W4250049866', 'https://openalex.org/W4252541936', 'https://openalex.org/W4255812818', 'https://openalex.org/W4323282383', 'https://openalex.org/W4362211646', 'https://openalex.org/W51818355', 'https://openalex.org/W71868372', 'https://openalex.org/W93818550'], 'related_works': ['https://openalex.org/W45453568', 'https://openalex.org/W2407460829', 'https://openalex.org/W2261290102', 'https://openalex.org/W2185219103', 'https://openalex.org/W2146729326', 'https://openalex.org/W2105670269', 'https://openalex.org/W2092753016', 'https://openalex.org/W201608531', 'https://openalex.org/W2000136537', 'https://openalex.org/W1983810387'], 'abstract_inverted_index': {'Bipolar': [0], 'patients': [1, 30, 47], 'generally': [2], 'spend': [3], 'much': [4], 'more': [5, 22], 'time': [6], 'in': [7, 45, 116, 147, 230], 'the': [8, 15, 53, 72, 105, 108, 122, 126, 129, 170, 179, 202, 225], 'depressed': [9, 54, 256], 'phase': [10, 55], 'of': [11, 43, 52, 56, 63, 74, 77, 110, 149, 169, 181, 204, 239], 'their': [12], 'illness': [13], 'than': [14, 31, 166], 'manic': [16], 'phase,': [17], 'and': [18, 26, 83, 88, 95, 140, 151, 155, 196, 243, 269], 'there': [19, 32, 38], 'are': [20, 33, 134, 198], 'many': [21], 'bipolar': [23, 27, 34, 46, 57, 111, 257], 'type': [24, 35], 'II': [25], 'spectrum': [28], 'disorder': [29, 58, 258], 'I.': [36], 'Additionally,': [37], 'is': [39, 59, 102, 113, 143, 206, 209, 235, 262], 'a': [40, 61, 183, 193, 237, 251], 'significant': [41], 'risk': [42, 180, 203], 'suicide': [44], 'when': [48], 'depressed.': [49], 'The': [50], 'treatment': [51, 109, 174, 254, 275], 'therefore': [60], 'matter': [62], 'some': [64, 145], 'priority.': [65], 'Here,': [66], 'we': [67], 'review': [68], 'current': [69], 'evidence': [70, 123, 131, 146, 212], 'supporting': [71], 'use': [73], 'five': [75], 'groups': [76], 'treatments:': [78], 'anti-depressants;': [79], 'lithium;': [80], 'anti-convulsants': [81], '(valproate,': [82], 'carbamazepine,': [84], 'lamotrigine,': [85], 'gabapentin);': [86], 'anti-psychotics;': [87], 'other': [89, 273], 'treatments': [90, 127], '(electroconvulsive': [91], 'therapy,': [92], 'benzodiazepines,': [93], 'sleep-deprivation,': [94], 'dopamine': [96], 'agonists).': [97], 'From': [98], 'this': [99, 228, 267], 'review,': [100, 229], 'it': [101, 271], 'apparent': [103], 'that': [104, 236], 'literature': [106], 'regarding': [107], 'depression': [112], 'significantly': [114], 'limited': [115], 'several': [117], 'key': [118], 'areas.': [119], 'Nonetheless,': [120], 'from': [121, 227], 'currently': [124], 'available,': [125], 'with': [128, 175, 272], 'best': [130], 'for': [132, 213, 218, 255], 'efficacy': [133], 'selective': [135], 'serotonin': [136], 'reuptake': [137], 'inhibitors': [138], '(SSRIs)': [139], 'lamotrigine.': [141], 'There': [142, 208], 'also': [144, 159, 210], 'favour': [148], 'bupropion': [150], 'moclobemide.': [152], 'Although': [153], 'lithium': [154], 'olanzapine': [156], 'monotherapies': [157], 'can': [158], 'be': [160], 'beneficial,': [161], 'they': [162], 'appear': [163], 'less': [164], 'efficacious': [165], 'antidepressants.': [167], 'One': [168], 'major': [171], 'concerns': [172], 'about': [173], 'antidepressants': [176], 'has': [177], 'been': [178], 'precipitating': [182], 'switch': [184], 'into': [185], 'mania.': [186], 'However,': [187], 'recent': [188, 211], 'studies': [189], 'suggest': [190], 'that,': [191], 'if': [192], 'mood': [194], 'stabilizer': [195], 'antidepressant': [197, 216], 'given': [199], 'concurrently,': [200], 'then': [201], 'switching': [205], 'minimized.': [207], 'an': [214, 240, 245], 'independent': [215], 'action': [217], 'at': [219], 'least': [220], 'one': [221], 'atypical': [222, 241], 'antipsychotic.': [223], 'Therefore,': [224], 'conclusion': [226], 'contrast': [231], 'to': [232, 265], 'previous': [233], 'suggestions,': [234], 'combination': [238], 'antipsychotic': [242], 'either': [244], 'SSRI': [246], 'or': [247], 'lamotrigine': [248], 'may': [249], 'provide': [250], 'useful': [252], 'first-line': [253], 'patients.': [259], 'Further': [260], 'research': [261], 'clearly': [263], 'required': [264], 'examine': [266], 'approach': [268], 'compare': [270], 'possible': [274], 'options.': [276]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2022871996', 'counts_by_year': [{'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-31T11:40:24.959976', 'created_date': '2016-06-24'}