Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2022664710', 'doi': 'https://doi.org/10.1016/j.bbagrm.2011.11.005', 'title': 'Mitochondrial DNA nucleoid structure', 'display_name': 'Mitochondrial DNA nucleoid structure', 'publication_year': 2011, 'publication_date': '2011-12-03', 'ids': {'openalex': 'https://openalex.org/W2022664710', 'doi': 'https://doi.org/10.1016/j.bbagrm.2011.11.005', 'mag': '2022664710', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22142616'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbagrm.2011.11.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210203689', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms', 'issn_l': '1874-9399', 'issn': ['1874-9399', '1876-4320'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5064165292', 'display_name': 'Daniel Bogenhagen', 'orcid': 'https://orcid.org/0000-0002-9993-2574'}, 'institutions': [{'id': 'https://openalex.org/I59553526', 'display_name': 'Stony Brook University', 'ror': 'https://ror.org/05qghxh33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I59553526']}, {'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Daniel F. Bogenhagen', 'raw_affiliation_strings': ['Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794-8651, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY 11794-8651, USA', 'institution_ids': ['https://openalex.org/I59553526', 'https://openalex.org/I1327163397']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5064165292'], 'corresponding_institution_ids': ['https://openalex.org/I59553526', 'https://openalex.org/I1327163397'], 'apc_list': None, 'apc_paid': None, 'fwci': 2.364, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 249, 'citation_normalized_percentile': {'value': 0.999716, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '1819', 'issue': '9-10', 'first_page': '914', 'last_page': '920'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Dynamics and Reactive Oxygen Species Regulation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Dynamics and Reactive Oxygen Species Regulation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11027', 'display_name': 'Metabolic Disorders and Biochemical Genetics', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'Ribosome Structure and Translation Mechanisms', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nucleoid', 'display_name': 'Nucleoid', 'score': 0.81564915}, {'id': 'https://openalex.org/keywords/rna-structure', 'display_name': 'RNA Structure', 'score': 0.54512}, {'id': 'https://openalex.org/keywords/organelle', 'display_name': 'Organelle', 'score': 0.48350528}], 'concepts': [{'id': 'https://openalex.org/C53642103', 'wikidata': 'https://www.wikidata.org/wiki/Q459485', 'display_name': 'Nucleoid', 'level': 4, 'score': 0.81564915}, {'id': 'https://openalex.org/C83640560', 'wikidata': 'https://www.wikidata.org/wiki/Q180951', 'display_name': 'Chromatin', 'level': 3, 'score': 0.7086174}, {'id': 'https://openalex.org/C24586158', 'wikidata': 'https://www.wikidata.org/wiki/Q27075', 'display_name': 'Mitochondrial DNA', 'level': 3, 'score': 0.69951844}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6757552}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.6436459}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.5779532}, {'id': 'https://openalex.org/C64927066', 'wikidata': 'https://www.wikidata.org/wiki/Q36293', 'display_name': 'Histone', 'level': 3, 'score': 0.5301448}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.51047075}, {'id': 'https://openalex.org/C153957851', 'wikidata': 'https://www.wikidata.org/wiki/Q201448', 'display_name': 'Transfer RNA', 'level': 4, 'score': 0.48388657}, {'id': 'https://openalex.org/C168240541', 'wikidata': 'https://www.wikidata.org/wiki/Q45948', 'display_name': 'Organelle', 'level': 2, 'score': 0.48350528}, {'id': 'https://openalex.org/C28859421', 'wikidata': 'https://www.wikidata.org/wiki/Q39572', 'display_name': 'Mitochondrion', 'level': 2, 'score': 0.48042083}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.47945774}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3814234}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.23109561}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004272', 'descriptor_name': 'DNA, Mitochondrial', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004272', 'descriptor_name': 'DNA, Mitochondrial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009707', 'descriptor_name': 'Nucleosomes', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009707', 'descriptor_name': 'Nucleosomes', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D009707', 'descriptor_name': 'Nucleosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012335', 'descriptor_name': 'RNA, Ribosomal', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012335', 'descriptor_name': 'RNA, Ribosomal', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012335', 'descriptor_name': 'RNA, Ribosomal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbagrm.2011.11.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210203689', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms', 'issn_l': '1874-9399', 'issn': ['1874-9399', '1876-4320'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22142616', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320306135', 'funder_display_name': 'Ellison Medical Foundation', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 98, 'referenced_works': ['https://openalex.org/W12952247', 'https://openalex.org/W1519160353', 'https://openalex.org/W1548912336', 'https://openalex.org/W1573889570', 'https://openalex.org/W1575382738', 'https://openalex.org/W1579112009', 'https://openalex.org/W1737281046', 'https://openalex.org/W1801560648', 'https://openalex.org/W1963625553', 'https://openalex.org/W1964758691', 'https://openalex.org/W1966276039', 'https://openalex.org/W1967390196', 'https://openalex.org/W1968197570', 'https://openalex.org/W1972645332', 'https://openalex.org/W1979809549', 'https://openalex.org/W1984543814', 'https://openalex.org/W1988121111', 'https://openalex.org/W1989840530', 'https://openalex.org/W1996592585', 'https://openalex.org/W1996943057', 'https://openalex.org/W2000007356', 'https://openalex.org/W2000454435', 'https://openalex.org/W2001709662', 'https://openalex.org/W2002635425', 'https://openalex.org/W2005314998', 'https://openalex.org/W2005318857', 'https://openalex.org/W2005520835', 'https://openalex.org/W2007153791', 'https://openalex.org/W2010300247', 'https://openalex.org/W2010957401', 'https://openalex.org/W2011116207', 'https://openalex.org/W2011135370', 'https://openalex.org/W2013571070', 'https://openalex.org/W2015181317', 'https://openalex.org/W2016160555', 'https://openalex.org/W2024185588', 'https://openalex.org/W2024595059', 'https://openalex.org/W2025779835', 'https://openalex.org/W2028323021', 'https://openalex.org/W2031665897', 'https://openalex.org/W2034418364', 'https://openalex.org/W2036791811', 'https://openalex.org/W2039071554', 'https://openalex.org/W2040175583', 'https://openalex.org/W2041959633', 'https://openalex.org/W2045824221', 'https://openalex.org/W2055006666', 'https://openalex.org/W2055557007', 'https://openalex.org/W2057289695', 'https://openalex.org/W2057695252', 'https://openalex.org/W2058153670', 'https://openalex.org/W2059430355', 'https://openalex.org/W2060177007', 'https://openalex.org/W2062063518', 'https://openalex.org/W2062630699', 'https://openalex.org/W2067322059', 'https://openalex.org/W2070842365', 'https://openalex.org/W2071668318', 'https://openalex.org/W2077283568', 'https://openalex.org/W2078844770', 'https://openalex.org/W2088001012', 'https://openalex.org/W2091543686', 'https://openalex.org/W2091998164', 'https://openalex.org/W2099352677', 'https://openalex.org/W2100702807', 'https://openalex.org/W2101814873', 'https://openalex.org/W2105688529', 'https://openalex.org/W2109942343', 'https://openalex.org/W2112264396', 'https://openalex.org/W2113434530', 'https://openalex.org/W2113623900', 'https://openalex.org/W2115512131', 'https://openalex.org/W2118397007', 'https://openalex.org/W2119165025', 'https://openalex.org/W2120005496', 'https://openalex.org/W2120695551', 'https://openalex.org/W2120997014', 'https://openalex.org/W2125577771', 'https://openalex.org/W2126354256', 'https://openalex.org/W2129398678', 'https://openalex.org/W2131402057', 'https://openalex.org/W2133572194', 'https://openalex.org/W2135457714', 'https://openalex.org/W2139004845', 'https://openalex.org/W2148885675', 'https://openalex.org/W2149682982', 'https://openalex.org/W2151698573', 'https://openalex.org/W2158592000', 'https://openalex.org/W2161291398', 'https://openalex.org/W2166393810', 'https://openalex.org/W2166664098', 'https://openalex.org/W2168310850', 'https://openalex.org/W2168754435', 'https://openalex.org/W2169506226', 'https://openalex.org/W2170353382', 'https://openalex.org/W2170819005', 'https://openalex.org/W2170946953', 'https://openalex.org/W293285070'], 'related_works': ['https://openalex.org/W2185911465', 'https://openalex.org/W2175891077', 'https://openalex.org/W2069932381', 'https://openalex.org/W2069207793', 'https://openalex.org/W2039193920', 'https://openalex.org/W2013429818', 'https://openalex.org/W1978523645', 'https://openalex.org/W1966276039', 'https://openalex.org/W1927685827', 'https://openalex.org/W1818252956'], 'abstract_inverted_index': {'Eukaryotic': [0], 'cells': [1, 37, 64], 'are': [2, 95], 'characterized': [3], 'by': [4], 'their': [5, 91], 'content': [6], 'of': [7, 29, 35, 69, 71, 110, 126, 136], 'intracellular': [8], 'membrane-bound': [9], 'organelles,': [10], 'including': [11], 'mitochondria': [12], 'as': [13, 15, 56, 101], 'well': [14], 'nuclei.': [16], 'These': [17], 'two': [18, 22], 'DNA-containing': [19], 'compartments': [20], 'employ': [21], 'distinct': [23], 'strategies': [24], 'for': [25, 90], 'storage': [26], 'and': [27, 86, 123], 'readout': [28], 'genetic': [30], 'information.': [31], 'The': [32, 93], 'diploid': [33], 'nuclei': [34], 'human': [36, 63], 'contain': [38, 65], 'about': [39, 45], '6': [40], 'billion': [41], 'base': [42], 'pairs': [43], 'encoding': [44], '25,000': [46], 'protein-encoding': [47], 'genes,': [48], 'averaging': [49], '120': [50], 'kB/gene,': [51], 'packaged': [52], 'in': [53, 118, 129], 'chromatin': [54], 'arranged': [55], 'a': [57, 72, 137], 'regular': [58], 'nucleosomal': [59], 'array.': [60], 'In': [61], 'contrast,': [62], 'hundreds': [66], 'to': [67], 'thousands': [68], 'copies': [70, 106], 'ca.16': [73], 'kB': [74], 'mtDNA': [75, 127], 'genome': [76], 'tightly': [77], 'packed': [78], 'with': [79, 84], '13': [80], 'protein-coding': [81], 'genes': [82, 88], 'along': [83], 'rRNA': [85], 'tRNA': [87], 'required': [89], 'expression.': [92], 'mtDNAs': [94], 'dispersed': [96], 'throughout': [97], 'the': [98, 120], 'mitochondrial': [99], 'network': [100], 'histone-free': [102], 'nucleoids': [103, 128], 'containing': [104], 'single': [105], 'or': [107], 'small': [108], 'clusters': [109], 'genomes.': [111], 'This': [112, 132], 'review': [113], 'will': [114], 'summarize': [115], 'recent': [116], 'advances': [117], 'understanding': [119], 'microscopic': [121], 'structure': [122], 'molecular': [124], 'composition': [125], 'higher': [130], 'eukaryotes.': [131], 'article': [133], 'is': [134], 'part': [135], 'Special': [138], 'Issue': [139], 'entitled:': [140], 'Mitochondrial': [141], 'Gene': [142], 'Expression.': [143]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2022664710', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 25}, {'year': 2022, 'cited_by_count': 27}, {'year': 2021, 'cited_by_count': 25}, {'year': 2020, 'cited_by_count': 14}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 26}, {'year': 2017, 'cited_by_count': 20}, {'year': 2016, 'cited_by_count': 22}, {'year': 2015, 'cited_by_count': 21}, {'year': 2014, 'cited_by_count': 22}, {'year': 2013, 'cited_by_count': 15}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-09-17T15:27:07.394479', 'created_date': '2016-06-24'}