Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2022543394', 'doi': 'https://doi.org/10.1016/0303-7207(75)90005-2', 'title': 'Inhibitors of protein and RNA synthesis and 1,25-dihydroxycholecalciferol formation in vitro', 'display_name': 'Inhibitors of protein and RNA synthesis and 1,25-dihydroxycholecalciferol formation in vitro', 'publication_year': 1975, 'publication_date': '1975-03-01', 'ids': {'openalex': 'https://openalex.org/W2022543394', 'doi': 'https://doi.org/10.1016/0303-7207(75)90005-2', 'mag': '2022543394', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1123104'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0303-7207(75)90005-2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191044671', 'display_name': 'Molecular and Cellular Endocrinology', 'issn_l': '0303-7207', 'issn': ['0303-7207', '1872-8057'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113786380', 'display_name': 'Richard G. Larkins', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210130048', 'display_name': 'Royal Victoria Hospital', 'ror': 'https://ror.org/03rq50d77', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1289110261', 'https://openalex.org/I4210130048']}, {'id': 'https://openalex.org/I138801177', 'display_name': 'University of Ulster', 'ror': 'https://ror.org/01yp9g959', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I138801177']}, {'id': 'https://openalex.org/I2801748203', 'display_name': 'Hammersmith Hospital', 'ror': 'https://ror.org/05jg8yp15', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2801748203']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'R.G. Larkins', 'raw_affiliation_strings': ['Endocrine Unit, Royal Postgraduate Medical School, Department of Chemical Pathology, Hammersmith Hospital, London W12, OHS U.K.'], 'affiliations': [{'raw_affiliation_string': 'Endocrine Unit, Royal Postgraduate Medical School, Department of Chemical Pathology, Hammersmith Hospital, London W12, OHS U.K.', 'institution_ids': ['https://openalex.org/I4210130048', 'https://openalex.org/I138801177', 'https://openalex.org/I2801748203']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080939577', 'display_name': 'S. J. MacAuley', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210130048', 'display_name': 'Royal Victoria Hospital', 'ror': 'https://ror.org/03rq50d77', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1289110261', 'https://openalex.org/I4210130048']}, {'id': 'https://openalex.org/I138801177', 'display_name': 'University of Ulster', 'ror': 'https://ror.org/01yp9g959', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I138801177']}, {'id': 'https://openalex.org/I2801748203', 'display_name': 'Hammersmith Hospital', 'ror': 'https://ror.org/05jg8yp15', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2801748203']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'S.J. Macauley', 'raw_affiliation_strings': ['Endocrine Unit, Royal Postgraduate Medical School, Department of Chemical Pathology, Hammersmith Hospital, London W12, OHS U.K.'], 'affiliations': [{'raw_affiliation_string': 'Endocrine Unit, Royal Postgraduate Medical School, Department of Chemical Pathology, Hammersmith Hospital, London W12, OHS U.K.', 'institution_ids': ['https://openalex.org/I4210130048', 'https://openalex.org/I138801177', 'https://openalex.org/I2801748203']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5004215185', 'display_name': 'I. MacIntyre', 'orcid': 'https://orcid.org/0000-0003-4420-3822'}, 'institutions': [{'id': 'https://openalex.org/I4210130048', 'display_name': 'Royal Victoria Hospital', 'ror': 'https://ror.org/03rq50d77', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1289110261', 'https://openalex.org/I4210130048']}, {'id': 'https://openalex.org/I138801177', 'display_name': 'University of Ulster', 'ror': 'https://ror.org/01yp9g959', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I138801177']}, {'id': 'https://openalex.org/I2801748203', 'display_name': 'Hammersmith Hospital', 'ror': 'https://ror.org/05jg8yp15', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2801748203']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'I. Macintyre', 'raw_affiliation_strings': ['Endocrine Unit, Royal Postgraduate Medical School, Department of Chemical Pathology, Hammersmith Hospital, London W12, OHS U.K.'], 'affiliations': [{'raw_affiliation_string': 'Endocrine Unit, Royal Postgraduate Medical School, Department of Chemical Pathology, Hammersmith Hospital, London W12, OHS U.K.', 'institution_ids': ['https://openalex.org/I4210130048', 'https://openalex.org/I138801177', 'https://openalex.org/I2801748203']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.967, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 18, 'citation_normalized_percentile': {'value': 0.671177, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '2', 'issue': '3', 'first_page': '193', 'last_page': '202'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11150', 'display_name': 'Endoplasmic Reticulum Stress and Disease', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11150', 'display_name': 'Endoplasmic Reticulum Stress and Disease', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12286', 'display_name': 'Erythrocyte Function and Pathophysiology', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12827', 'display_name': 'Biochemical and Molecular Research', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/puromycin', 'display_name': 'Puromycin', 'score': 0.93688333}, {'id': 'https://openalex.org/keywords/dactinomycin', 'display_name': 'Dactinomycin', 'score': 0.53917706}], 'concepts': [{'id': 'https://openalex.org/C2778128677', 'wikidata': 'https://www.wikidata.org/wiki/Q412895', 'display_name': 'Cycloheximide', 'level': 3, 'score': 0.97815955}, {'id': 'https://openalex.org/C2779200571', 'wikidata': 'https://www.wikidata.org/wiki/Q424696', 'display_name': 'Puromycin', 'level': 3, 'score': 0.93688333}, {'id': 'https://openalex.org/C3675279', 'wikidata': 'https://www.wikidata.org/wiki/Q211935', 'display_name': 'Protein biosynthesis', 'level': 2, 'score': 0.77565193}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.65790665}, {'id': 'https://openalex.org/C24998067', 'wikidata': 'https://www.wikidata.org/wiki/Q4114622', 'display_name': 'Stimulation', 'level': 2, 'score': 0.59020615}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5838636}, {'id': 'https://openalex.org/C2776695378', 'wikidata': 'https://www.wikidata.org/wiki/Q186127', 'display_name': 'Dactinomycin', 'level': 4, 'score': 0.53917706}, {'id': 'https://openalex.org/C25642318', 'wikidata': 'https://www.wikidata.org/wiki/Q1992532', 'display_name': 'Incubation', 'level': 2, 'score': 0.50940615}, {'id': 'https://openalex.org/C28212737', 'wikidata': 'https://www.wikidata.org/wiki/Q5381543', 'display_name': 'Enzyme assay', 'level': 3, 'score': 0.4915596}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.488164}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.48410332}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.48244077}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.42750898}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.37231487}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3559487}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.34660047}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D004100', 'descriptor_name': 'Dihydroxycholecalciferols', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D006887', 'descriptor_name': 'Hydroxycholecalciferols', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D007684', 'descriptor_name': 'Kidney Tubules', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014176', 'descriptor_name': 'Protein Biosynthesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D000546', 'descriptor_name': 'Amanitins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000546', 'descriptor_name': 'Amanitins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002645', 'descriptor_name': 'Chickens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003513', 'descriptor_name': 'Cycloheximide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003513', 'descriptor_name': 'Cycloheximide', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D003609', 'descriptor_name': 'Dactinomycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003609', 'descriptor_name': 'Dactinomycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D003864', 'descriptor_name': 'Depression, Chemical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004100', 'descriptor_name': 'Dihydroxycholecalciferols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006887', 'descriptor_name': 'Hydroxycholecalciferols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007684', 'descriptor_name': 'Kidney Tubules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007684', 'descriptor_name': 'Kidney Tubules', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011691', 'descriptor_name': 'Puromycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011691', 'descriptor_name': 'Puromycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0303-7207(75)90005-2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191044671', 'display_name': 'Molecular and Cellular Endocrinology', 'issn_l': '0303-7207', 'issn': ['0303-7207', '1872-8057'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1123104', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1437796291', 'https://openalex.org/W1502976322', 'https://openalex.org/W1554181408', 'https://openalex.org/W1575735806', 'https://openalex.org/W1967946050', 'https://openalex.org/W1983775630', 'https://openalex.org/W2019551545', 'https://openalex.org/W2022909845', 'https://openalex.org/W2023881622', 'https://openalex.org/W2038116500', 'https://openalex.org/W2041745844', 'https://openalex.org/W2047996698', 'https://openalex.org/W2048597325', 'https://openalex.org/W2080759619', 'https://openalex.org/W2083021879', 'https://openalex.org/W2092959403', 'https://openalex.org/W2132966886', 'https://openalex.org/W2152828858', 'https://openalex.org/W2271008403', 'https://openalex.org/W50976702'], 'related_works': ['https://openalex.org/W2416922799', 'https://openalex.org/W2167414261', 'https://openalex.org/W2092502122', 'https://openalex.org/W2049621312', 'https://openalex.org/W2028180603', 'https://openalex.org/W2022543394', 'https://openalex.org/W2022337075', 'https://openalex.org/W1992083144', 'https://openalex.org/W1980224338', 'https://openalex.org/W1599027486'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2022543394', 'counts_by_year': [{'year': 2018, 'cited_by_count': 1}], 'updated_date': '2025-01-17T20:50:19.908114', 'created_date': '2016-06-24'}