Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2022268574', 'doi': 'https://doi.org/10.1016/j.actatropica.2012.09.011', 'title': 'Recombinant Leishmania (Leishmania) infantum Ecto-Nucleoside Triphosphate Diphosphohydrolase NTPDase-2 as a new antigen in canine visceral leishmaniasis diagnosis', 'display_name': 'Recombinant Leishmania (Leishmania) infantum Ecto-Nucleoside Triphosphate Diphosphohydrolase NTPDase-2 as a new antigen in canine visceral leishmaniasis diagnosis', 'publication_year': 2012, 'publication_date': '2012-09-26', 'ids': {'openalex': 'https://openalex.org/W2022268574', 'doi': 'https://doi.org/10.1016/j.actatropica.2012.09.011', 'mag': '2022268574', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23022017'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.actatropica.2012.09.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S190456265', 'display_name': 'Acta Tropica', 'issn_l': '0001-706X', 'issn': ['0001-706X', '1873-6254'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://doi.org/10.1016/j.actatropica.2012.09.011', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108673786', 'display_name': 'Ronny Francisco de Souza', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146165071', 'display_name': 'Universidade Federal de Viçosa', 'ror': 'https://ror.org/0409dgb37', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I146165071']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Ronny Francisco de Souza', 'raw_affiliation_strings': ['Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I146165071']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068349836', 'display_name': 'Yaro Luciolo dos Santos', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146165071', 'display_name': 'Universidade Federal de Viçosa', 'ror': 'https://ror.org/0409dgb37', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I146165071']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Yaro Luciolo dos Santos', 'raw_affiliation_strings': ['Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I146165071']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006934979', 'display_name': 'Raphael de Souza Vasconcellos', 'orcid': 'https://orcid.org/0000-0002-5064-052X'}, 'institutions': [{'id': 'https://openalex.org/I146165071', 'display_name': 'Universidade Federal de Viçosa', 'ror': 'https://ror.org/0409dgb37', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I146165071']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Raphael de Souza Vasconcellos', 'raw_affiliation_strings': ['Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'Instituto Nacional de Biotecnologia Estrutural e Química Medicinal em Doenças Infecciosas-INBEQMeDI, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Instituto Nacional de Biotecnologia Estrutural e Química Medicinal em Doenças Infecciosas-INBEQMeDI, Brazil', 'institution_ids': []}, {'raw_affiliation_string': 'Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I146165071']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007636209', 'display_name': 'Lucas Borges‐Pereira', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146165071', 'display_name': 'Universidade Federal de Viçosa', 'ror': 'https://ror.org/0409dgb37', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I146165071']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Lucas Borges-Pereira', 'raw_affiliation_strings': ['Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I146165071']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083247417', 'display_name': 'Ivo Santana Caldas', 'orcid': 'https://orcid.org/0000-0002-4937-2425'}, 'institutions': [{'id': 'https://openalex.org/I10824318', 'display_name': 'Universidade Federal de Ouro Preto', 'ror': 'https://ror.org/056s65p46', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I10824318']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Ivo Santana Caldas', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Biológicas – NUPEB, Universidade Federal de Ouro Preto, Ouro Preto, CEP 35400-000, MG, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Biológicas – NUPEB, Universidade Federal de Ouro Preto, Ouro Preto, CEP 35400-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I10824318']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109988512', 'display_name': 'Márcia Rogéria de Almeida', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146165071', 'display_name': 'Universidade Federal de Viçosa', 'ror': 'https://ror.org/0409dgb37', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I146165071']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Márcia Rogéria de Almeida', 'raw_affiliation_strings': ['Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I146165071']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077424635', 'display_name': 'Maria Terezinha Bahia', 'orcid': 'https://orcid.org/0000-0003-1486-9455'}, 'institutions': [{'id': 'https://openalex.org/I10824318', 'display_name': 'Universidade Federal de Ouro Preto', 'ror': 'https://ror.org/056s65p46', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I10824318']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Maria Terezinha Bahia', 'raw_affiliation_strings': ['Núcleo de Pesquisa em Ciências Biológicas – NUPEB, Universidade Federal de Ouro Preto, Ouro Preto, CEP 35400-000, MG, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Núcleo de Pesquisa em Ciências Biológicas – NUPEB, Universidade Federal de Ouro Preto, Ouro Preto, CEP 35400-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I10824318']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072137122', 'display_name': 'Juliana Lopes Rangel Fietto', 'orcid': 'https://orcid.org/0000-0001-6122-1710'}, 'institutions': [{'id': 'https://openalex.org/I146165071', 'display_name': 'Universidade Federal de Viçosa', 'ror': 'https://ror.org/0409dgb37', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I146165071']}], 'countries': ['BR'], 'is_corresponding': True, 'raw_author_name': 'Juliana Lopes Rangel Fietto', 'raw_affiliation_strings': ['Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'Instituto Nacional de Biotecnologia Estrutural e Química Medicinal em Doenças Infecciosas-INBEQMeDI, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Bioquímica e Biologia Molecular, Universidade Federal de Viçosa, Viçosa, CEP 36570-000, MG, Brazil', 'institution_ids': ['https://openalex.org/I146165071']}, {'raw_affiliation_string': 'Instituto Nacional de Biotecnologia Estrutural e Química Medicinal em Doenças Infecciosas-INBEQMeDI, Brazil', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5072137122'], 'corresponding_institution_ids': ['https://openalex.org/I146165071'], 'apc_list': {'value': 3040, 'currency': 'USD', 'value_usd': 3040, 'provenance': 'doaj'}, 'apc_paid': {'value': 3040, 'currency': 'USD', 'value_usd': 3040, 'provenance': 'doaj'}, 'fwci': 2.528, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.917541, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '125', 'issue': '1', 'first_page': '60', 'last_page': '66'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10823', 'display_name': 'Research on Leishmaniasis Studies', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10823', 'display_name': 'Research on Leishmaniasis Studies', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10890', 'display_name': 'Trypanosoma species research and implications', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11193', 'display_name': 'Adenosine and Purinergic Signaling', 'score': 0.9871, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/canine-leishmaniasis', 'display_name': 'Canine leishmaniasis', 'score': 0.7957995}, {'id': 'https://openalex.org/keywords/leishmania-chagasi', 'display_name': 'Leishmania chagasi', 'score': 0.4671625}], 'concepts': [{'id': 'https://openalex.org/C2781257258', 'wikidata': 'https://www.wikidata.org/wiki/Q1950789', 'display_name': 'Leishmania infantum', 'level': 4, 'score': 0.9423028}, {'id': 'https://openalex.org/C2778689377', 'wikidata': 'https://www.wikidata.org/wiki/Q2046113', 'display_name': 'Visceral leishmaniasis', 'level': 3, 'score': 0.9369879}, {'id': 'https://openalex.org/C2777625542', 'wikidata': 'https://www.wikidata.org/wiki/Q5032413', 'display_name': 'Canine leishmaniasis', 'level': 5, 'score': 0.7957995}, {'id': 'https://openalex.org/C2776555147', 'wikidata': 'https://www.wikidata.org/wiki/Q331283', 'display_name': 'Leishmaniasis', 'level': 2, 'score': 0.7509525}, {'id': 'https://openalex.org/C2781092759', 'wikidata': 'https://www.wikidata.org/wiki/Q524818', 'display_name': 'Leishmania', 'level': 3, 'score': 0.6766063}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.6456302}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.5684528}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.53084266}, {'id': 'https://openalex.org/C2909011054', 'wikidata': 'https://www.wikidata.org/wiki/Q1950789', 'display_name': 'Leishmania chagasi', 'level': 4, 'score': 0.4671625}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.4583248}, {'id': 'https://openalex.org/C71928629', 'wikidata': 'https://www.wikidata.org/wiki/Q804206', 'display_name': 'Parasite hosting', 'level': 2, 'score': 0.15315789}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000251', 'descriptor_name': 'Adenosine Triphosphatases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019411', 'descriptor_name': 'Clinical Laboratory Techniques', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D004283', 'descriptor_name': 'Dog Diseases', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D018314', 'descriptor_name': 'Leishmania infantum', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': True}, {'descriptor_ui': 'D007898', 'descriptor_name': 'Leishmaniasis, Visceral', 'qualifier_ui': 'Q000662', 'qualifier_name': 'veterinary', 'is_major_topic': True}, {'descriptor_ui': 'D010274', 'descriptor_name': 'Parasitology', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D014730', 'descriptor_name': 'Veterinary Medicine', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D000251', 'descriptor_name': 'Adenosine Triphosphatases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000953', 'descriptor_name': 'Antigens, Protozoan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000953', 'descriptor_name': 'Antigens, Protozoan', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019411', 'descriptor_name': 'Clinical Laboratory Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016054', 'descriptor_name': 'DNA, Protozoan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016054', 'descriptor_name': 'DNA, Protozoan', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D016054', 'descriptor_name': 'DNA, Protozoan', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004283', 'descriptor_name': 'Dog Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004283', 'descriptor_name': 'Dog Diseases', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D004285', 'descriptor_name': 'Dogs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004797', 'descriptor_name': 'Enzyme-Linked Immunosorbent Assay', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004797', 'descriptor_name': 'Enzyme-Linked Immunosorbent Assay', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018314', 'descriptor_name': 'Leishmania infantum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007898', 'descriptor_name': 'Leishmaniasis, Visceral', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D007898', 'descriptor_name': 'Leishmaniasis, Visceral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010274', 'descriptor_name': 'Parasitology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014730', 'descriptor_name': 'Veterinary Medicine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.actatropica.2012.09.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S190456265', 'display_name': 'Acta Tropica', 'issn_l': '0001-706X', 'issn': ['0001-706X', '1873-6254'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://www.locus.ufv.br/handle/123456789/12625', 'pdf_url': 'https://locus.ufv.br//bitstream/123456789/12625/1/1-s2.0-S0001706X12003166-main.pdf', 'source': {'id': 'https://openalex.org/S4306400786', 'display_name': 'Americanae (AECID Library)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://www.repositorio.ufop.br/handle/123456789/4928', 'pdf_url': 'http://www.repositorio.ufop.br/jspui/bitstream/123456789/4928/1/ARTIGO_RecombinantLeishmaniaLeishmania.pdf', 'source': {'id': 'https://openalex.org/S4306402641', 'display_name': 'LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I4383465926', 'host_organization_name': 'LA Referencia', 'host_organization_lineage': ['https://openalex.org/I4383465926'], 'host_organization_lineage_names': ['LA Referencia'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23022017', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.actatropica.2012.09.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S190456265', 'display_name': 'Acta Tropica', 'issn_l': '0001-706X', 'issn': ['0001-706X', '1873-6254'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Sustainable cities and communities', 'id': 'https://metadata.un.org/sdg/11', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1772540997', 'https://openalex.org/W1840052409', 'https://openalex.org/W1981737897', 'https://openalex.org/W1998693545', 'https://openalex.org/W2022345289', 'https://openalex.org/W2046306052', 'https://openalex.org/W2055389258', 'https://openalex.org/W2058410729', 'https://openalex.org/W2059364805', 'https://openalex.org/W2064797931', 'https://openalex.org/W2084059035', 'https://openalex.org/W2096906633', 'https://openalex.org/W2098031413', 'https://openalex.org/W2098798785', 'https://openalex.org/W2099284132', 'https://openalex.org/W2111518271', 'https://openalex.org/W2115187706', 'https://openalex.org/W2116056104', 'https://openalex.org/W2116708519', 'https://openalex.org/W2121411268', 'https://openalex.org/W2123191684', 'https://openalex.org/W2128934286', 'https://openalex.org/W2129191015', 'https://openalex.org/W2135073781', 'https://openalex.org/W2138133068', 'https://openalex.org/W2138505632', 'https://openalex.org/W2138599948', 'https://openalex.org/W2138749645', 'https://openalex.org/W2139588481', 'https://openalex.org/W2150127515', 'https://openalex.org/W2160784956', 'https://openalex.org/W2306346490', 'https://openalex.org/W2804007336'], 'related_works': ['https://openalex.org/W2903001743', 'https://openalex.org/W2427615828', 'https://openalex.org/W2227211840', 'https://openalex.org/W2126683399', 'https://openalex.org/W2116790292', 'https://openalex.org/W2115957392', 'https://openalex.org/W2077000196', 'https://openalex.org/W2065953118', 'https://openalex.org/W2022268574', 'https://openalex.org/W1139037058'], 'abstract_inverted_index': {'Canine': [0], 'visceral': [1, 15, 64], 'leishmaniasis': [2, 51, 65, 190, 211], 'is': [3, 59], 'an': [4], 'important': [5], 'public': [6], 'health': [7], 'concern.': [8], 'In': [9, 70], 'the': [10, 20, 60, 67, 90, 109, 121, 178, 193], 'epidemiological': [11], 'context': [12], 'of': [13, 23, 50, 63, 92, 101, 150, 160, 170, 181, 188, 195], 'human': [14, 39, 210], 'leishmaniasis,': [16], 'dogs': [17, 27], 'are': [18], 'considered': [19], 'main': [21], 'reservoir': [22], 'Leishmania': [24, 54], 'parasites;': [25], 'therefore,': [26], 'must': [28], 'be': [29], 'epidemiologically': [30], 'monitored': [31], 'constantly': [32], 'in': [33, 66, 89, 108, 185], 'endemic': [34], 'areas.': [35], 'Furthermore,': [36], 'dog': [37], 'to': [38, 119, 198], 'transmission': [40], 'has': [41], 'been': [42], 'correlated': [43], 'with': [44, 166], 'emerging': [45], 'urbanization': [46], 'and': [47, 96, 106, 138, 156, 191, 209], 'increasing': [48], 'rates': [49], 'infection': [52], 'worldwide.': [53], '(Leishmania)': [55], 'infantum': [56, 77], '(L.': [57, 78], 'chagasi)': [58, 79], 'etiologic': [61], 'agent': [62], 'New': [68], 'World.': [69], 'this': [71, 182], 'work,': [72], 'a': [73, 126, 147, 157, 167], 'new': [74], 'L.': [75], '(L.)': [76], 'recombinant': [80, 183], 'antigen,': [81], 'named': [82], 'ATP': [83, 102], 'diphosphohydrolase': [84, 103], '(rLic-NTPDase-2),': [85], 'intended': [86], 'for': [87], 'use': [88, 180], 'immunodiagnosis': [91], 'CVL': [93], 'was': [94, 104], 'produced': [95], 'validated.': [97], 'The': [98, 144], 'extracellular': [99], 'domain': [100], 'cloned': [105], 'expressed': [107], 'pET21b-Escherichia': [110], 'coli': [111], 'expression': [112], 'system.': [113], 'Indirect': [114], 'ELISA': [115], 'assays': [116, 208], 'were': [117], 'used': [118], 'detect': [120], 'purified': [122], 'rLic-NTPDase-2': [123], 'antigen': [124], 'using': [125], 'standard': [127], 'canine': [128, 189], 'sera': [129], 'library.': [130], 'This': [131], 'library': [132], 'contained': [133], 'CVL-positive': [134], 'samples,': [135], 'leishmaniasis-negative': [136], 'samples': [137, 139], 'from': [140], 'Trypanosoma': [141], 'cruzi-infected': [142], 'dogs.': [143], 'results': [145], 'show': [146], 'high': [148, 158, 168], 'sensitivity': [149], '100%': [151, 161], '(95%': [152, 162], 'CI': [153, 163], '=': [154, 164, 173], '92.60–100.0%)': [155], 'specificity': [159], '86.77–100.0%),': [165], 'degree': [169], 'confidence': [171], '(k': [172], '1).': [174], 'These': [175], 'findings': [176], 'demonstrate': [177], 'potential': [179], 'protein': [184], 'immune': [186], 'diagnosis': [187], 'open': [192], 'possibility': [194], 'its': [196], 'application': [197], 'other': [199], 'diagnostic': [200], 'approaches,': [201], 'such': [202], 'as': [203], 'immunochromatography': [204], 'fast': [205], 'lateral': [206], 'flow': [207], 'diagnosis.': [212]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2022268574', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 5}], 'updated_date': '2024-12-16T06:12:52.616688', 'created_date': '2016-06-24'}