Publication Information

{'id': 'https://openalex.org/W2022245027', 'doi': 'https://doi.org/10.1111/j.1365-2249.2006.03214.x', 'title': 'Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice', 'display_name': 'Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice', 'publication_year': 2006, 'publication_date': '2006-09-27', 'ids': {'openalex': 'https://openalex.org/W2022245027', 'doi': 'https://doi.org/10.1111/j.1365-2249.2006.03214.x', 'mag': '2022245027', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17034586', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1942055'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2249.2006.03214.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S11896317', 'display_name': 'Clinical & Experimental Immunology', 'issn_l': '0009-9104', 'issn': ['0009-9104', '1365-2249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942055', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108435576', 'display_name': 'Reiko Ito', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150208', 'display_name': 'Molecular Oncology (United States)', 'ror': 'https://ror.org/04rtkc841', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210150208']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R Ito', 'raw_affiliation_strings': ['Departments of Microbiology', 'Molecular Gastroenterology and Hepatology'], 'affiliations': [{'raw_affiliation_string': 'Departments of Microbiology', 'institution_ids': []}, {'raw_affiliation_string': 'Molecular Gastroenterology and Hepatology', 'institution_ids': ['https://openalex.org/I4210150208']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055615011', 'display_name': 'Masaharu Shin‐Ya', 'orcid': 'https://orcid.org/0000-0003-0710-0074'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M Shin-Ya', 'raw_affiliation_strings': ['Departments of Microbiology'], 'affiliations': [{'raw_affiliation_string': 'Departments of Microbiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110457809', 'display_name': 'T Kishida', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'T Kishida', 'raw_affiliation_strings': ['Departments of Microbiology'], 'affiliations': [{'raw_affiliation_string': 'Departments of Microbiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013137101', 'display_name': 'Atsuyo Urano', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I65143321', 'display_name': 'Hitachi (Japan)', 'ror': 'https://ror.org/02exqgm79', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I65143321']}, {'id': 'https://openalex.org/I4210143417', 'display_name': 'Public Works Research Institute', 'ror': 'https://ror.org/04b8j4a33', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210143417']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'A Urano', 'raw_affiliation_strings': ['Life Science Promotion Center, Hitachi Government and Public Corporation System Engineering, Ltd, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Life Science Promotion Center, Hitachi Government and Public Corporation System Engineering, Ltd, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I65143321', 'https://openalex.org/I4210143417']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024345452', 'display_name': 'Ryusuke Takada', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150208', 'display_name': 'Molecular Oncology (United States)', 'ror': 'https://ror.org/04rtkc841', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210150208']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R Takada', 'raw_affiliation_strings': ['Molecular Gastroenterology and Hepatology'], 'affiliations': [{'raw_affiliation_string': 'Molecular Gastroenterology and Hepatology', 'institution_ids': ['https://openalex.org/I4210150208']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100968572', 'display_name': 'Junichi Sakagami', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150208', 'display_name': 'Molecular Oncology (United States)', 'ror': 'https://ror.org/04rtkc841', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210150208']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J Sakagami', 'raw_affiliation_strings': ['Molecular Gastroenterology and Hepatology'], 'affiliations': [{'raw_affiliation_string': 'Molecular Gastroenterology and Hepatology', 'institution_ids': ['https://openalex.org/I4210150208']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060693017', 'display_name': 'Jirô Imanishi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J Imanishi', 'raw_affiliation_strings': ['Departments of Microbiology'], 'affiliations': [{'raw_affiliation_string': 'Departments of Microbiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079116380', 'display_name': 'Masaki Kita', 'orcid': 'https://orcid.org/0000-0001-6685-4461'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'M Kita', 'raw_affiliation_strings': ['Departments of Microbiology'], 'affiliations': [{'raw_affiliation_string': 'Departments of Microbiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084935260', 'display_name': 'Yoshihiro Ueda', 'orcid': 'https://orcid.org/0000-0002-1112-9841'}, 'institutions': [{'id': 'https://openalex.org/I40677808', 'display_name': 'Kyoto Prefectural University of Medicine', 'ror': 'https://ror.org/028vxwa22', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I40677808']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Y Ueda', 'raw_affiliation_strings': ['Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan'], 'affiliations': [{'raw_affiliation_string': 'Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan', 'institution_ids': ['https://openalex.org/I40677808']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074919264', 'display_name': 'Yoichiro Iwakura', 'orcid': 'https://orcid.org/0000-0002-9934-5775'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I161296585', 'display_name': 'Tokyo University of Science', 'ror': 'https://ror.org/05sj3n476', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I161296585']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Y Iwakura', 'raw_affiliation_strings': ['Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I74801974', 'https://openalex.org/I161296585']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024179981', 'display_name': 'Keisuke Kataoka', 'orcid': 'https://orcid.org/0000-0002-8263-9902'}, 'institutions': [{'id': 'https://openalex.org/I4210150208', 'display_name': 'Molecular Oncology (United States)', 'ror': 'https://ror.org/04rtkc841', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210150208']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'K Kataoka', 'raw_affiliation_strings': ['Molecular Gastroenterology and Hepatology'], 'affiliations': [{'raw_affiliation_string': 'Molecular Gastroenterology and Hepatology', 'institution_ids': ['https://openalex.org/I4210150208']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017078328', 'display_name': 'Takeshi Okanoue', 'orcid': 'https://orcid.org/0000-0002-2390-3400'}, 'institutions': [{'id': 'https://openalex.org/I4210150208', 'display_name': 'Molecular Oncology (United States)', 'ror': 'https://ror.org/04rtkc841', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210150208']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T Okanoue', 'raw_affiliation_strings': ['Molecular Gastroenterology and Hepatology'], 'affiliations': [{'raw_affiliation_string': 'Molecular Gastroenterology and Hepatology', 'institution_ids': ['https://openalex.org/I4210150208']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5024134678', 'display_name': 'Osam Mazda', 'orcid': 'https://orcid.org/0000-0001-9489-3556'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'O Mazda', 'raw_affiliation_strings': ['Departments of Microbiology'], 'affiliations': [{'raw_affiliation_string': 'Departments of Microbiology', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5024134678'], 'corresponding_institution_ids': [], 'apc_list': {'value': 2650, 'currency': 'GBP', 'value_usd': 3250, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.028, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 342, 'citation_normalized_percentile': {'value': 0.999932, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '146', 'issue': '2', 'first_page': '330', 'last_page': '338'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11532', 'display_name': 'Chemokine receptors and signaling', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11532', 'display_name': 'Chemokine receptors and signaling', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/proinflammatory-cytokine', 'display_name': 'Proinflammatory cytokine', 'score': 0.6517879}, {'id': 'https://openalex.org/keywords/monokine', 'display_name': 'Monokine', 'score': 0.47869068}], 'concepts': [{'id': 'https://openalex.org/C164027704', 'wikidata': 'https://www.wikidata.org/wiki/Q3491837', 'display_name': 'Proinflammatory cytokine', 'level': 3, 'score': 0.6517879}, {'id': 'https://openalex.org/C2780841837', 'wikidata': 'https://www.wikidata.org/wiki/Q24741149', 'display_name': 'Interferon gamma', 'level': 3, 'score': 0.62570727}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.6145722}, {'id': 'https://openalex.org/C2778260677', 'wikidata': 'https://www.wikidata.org/wiki/Q917447', 'display_name': 'Inflammatory bowel disease', 'level': 3, 'score': 0.6049752}, {'id': 'https://openalex.org/C13373296', 'wikidata': 'https://www.wikidata.org/wiki/Q421866', 'display_name': 'Chemokine', 'level': 3, 'score': 0.5742034}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.5291113}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.51578784}, {'id': 'https://openalex.org/C2779603739', 'wikidata': 'https://www.wikidata.org/wiki/Q6470553', 'display_name': 'Monokine', 'level': 4, 'score': 0.47869068}, {'id': 'https://openalex.org/C2775862500', 'wikidata': 'https://www.wikidata.org/wiki/Q2453464', 'display_name': 'Colitis', 'level': 2, 'score': 0.46676275}, {'id': 'https://openalex.org/C203565725', 'wikidata': 'https://www.wikidata.org/wiki/Q420012', 'display_name': 'Myeloperoxidase', 'level': 3, 'score': 0.42388743}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3854413}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.34135026}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.26997903}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.1297617}], 'mesh': [{'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000208', 'descriptor_name': 'Acute Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018932', 'descriptor_name': 'Chemokine CCL2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018932', 'descriptor_name': 'Chemokine CCL2', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D054357', 'descriptor_name': 'Chemokine CXCL10', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054370', 'descriptor_name': 'Chemokine CXCL9', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019743', 'descriptor_name': 'Chemokines, CXC', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019743', 'descriptor_name': 'Chemokines, CXC', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D003106', 'descriptor_name': 'Colon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003106', 'descriptor_name': 'Colon', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D016264', 'descriptor_name': 'Dextran Sulfate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004198', 'descriptor_name': 'Disease Susceptibility', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009195', 'descriptor_name': 'Peroxidase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009195', 'descriptor_name': 'Peroxidase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015431', 'descriptor_name': 'Weight Loss', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2249.2006.03214.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S11896317', 'display_name': 'Clinical & Experimental Immunology', 'issn_l': '0009-9104', 'issn': ['0009-9104', '1365-2249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942055', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17034586', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942055', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.66, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 69, 'referenced_works': ['https://openalex.org/W1565959221', 'https://openalex.org/W1597959509', 'https://openalex.org/W1602835962', 'https://openalex.org/W1606902694', 'https://openalex.org/W160934395', 'https://openalex.org/W1637709771', 'https://openalex.org/W1639777098', 'https://openalex.org/W1770444308', 'https://openalex.org/W1813646352', 'https://openalex.org/W1855226200', 'https://openalex.org/W1926035455', 'https://openalex.org/W1966961395', 'https://openalex.org/W1969963380', 'https://openalex.org/W1971119469', 'https://openalex.org/W1981190747', 'https://openalex.org/W1981327571', 'https://openalex.org/W1981859543', 'https://openalex.org/W1987778106', 'https://openalex.org/W1988019016', 'https://openalex.org/W1992291375', 'https://openalex.org/W2000119033', 'https://openalex.org/W2002427790', 'https://openalex.org/W2006371190', 'https://openalex.org/W2006654054', 'https://openalex.org/W2009680323', 'https://openalex.org/W2013888332', 'https://openalex.org/W2017328476', 'https://openalex.org/W2020087526', 'https://openalex.org/W2023325143', 'https://openalex.org/W2028882736', 'https://openalex.org/W2036403755', 'https://openalex.org/W2043647235', 'https://openalex.org/W2045281561', 'https://openalex.org/W2046412495', 'https://openalex.org/W2050445005', 'https://openalex.org/W2051836311', 'https://openalex.org/W2054164832', 'https://openalex.org/W2056939719', 'https://openalex.org/W2057447694', 'https://openalex.org/W2057626594', 'https://openalex.org/W2058100963', 'https://openalex.org/W2059072304', 'https://openalex.org/W2060741577', 'https://openalex.org/W2060866254', 'https://openalex.org/W2062942063', 'https://openalex.org/W2086196933', 'https://openalex.org/W2090305209', 'https://openalex.org/W2092424797', 'https://openalex.org/W2105360761', 'https://openalex.org/W2108229642', 'https://openalex.org/W2113855055', 'https://openalex.org/W2114029992', 'https://openalex.org/W2116761160', 'https://openalex.org/W2120056104', 'https://openalex.org/W2133260339', 'https://openalex.org/W2149958822', 'https://openalex.org/W2153869022', 'https://openalex.org/W2154824668', 'https://openalex.org/W2163647166', 'https://openalex.org/W2166372209', 'https://openalex.org/W2253732259', 'https://openalex.org/W2334402680', 'https://openalex.org/W2402628576', 'https://openalex.org/W2996355482', 'https://openalex.org/W3000793605', 'https://openalex.org/W407114964', 'https://openalex.org/W4211264883', 'https://openalex.org/W4291777677', 'https://openalex.org/W4313331693'], 'related_works': ['https://openalex.org/W2795010423', 'https://openalex.org/W2314334159', 'https://openalex.org/W2257717364', 'https://openalex.org/W2151925533', 'https://openalex.org/W2120640738', 'https://openalex.org/W2101357039', 'https://openalex.org/W2052433487', 'https://openalex.org/W2010502980', 'https://openalex.org/W1991495317', 'https://openalex.org/W1770444308'], 'abstract_inverted_index': {'Cytokines': [0], 'may': [1], 'be': [2], 'crucially': [3], 'involved': [4], 'in': [5, 49, 55, 72, 119, 122, 173, 201, 222, 233], 'the': [6, 30, 33, 73, 103, 125, 128, 133, 136, 165, 202, 223], 'pathogenesis': [7], 'of': [8, 70, 78, 86, 105, 111, 124, 127, 135, 149, 155, 161, 183, 205, 209, 225], 'inflammatory': [9, 162], 'bowel': [10, 129], 'diseases': [11], '(IBD),': [12], 'but': [13, 207], 'it': [14], 'remains': [15], 'controversial': [16], 'whether': [17], 'interferon': [18], '(IFN)-gamma,': [19], 'a': [20, 67, 75], 'typical': [21], 'proinflammatory': [22], 'cytokine,': [23], 'is': [24], 'an': [25, 234], 'essential': [26], 'mediator': [27], 'to': [28, 57], 'cause': [29], 'disorders.': [31], 'In': [32, 89], 'present': [34, 213], 'study,': [35], 'IFN-gamma(-/-)': [36, 168, 210], 'and': [37, 108, 143, 158, 196, 228], 'wild-type': [38], '(WT)': [39], 'C57BL/6': [40], 'mice': [41, 65, 94, 169], 'were': [42], 'fed': [43], '2.5%': [44], 'dextran': [45], 'sodium': [46], 'sulphate': [47], '(DSS)': [48], 'drinking': [50], 'water': [51], 'for': [52], '7': [53], 'days,': [54], 'order': [56], 'investigate': [58], 'DSS-induced': [59, 98], 'intestinal': [60, 114], 'inflammation.': [61], 'The': [62, 212], 'DSS-treated': [63, 150], 'WT': [64, 120, 151, 206], 'exhibited': [66], 'robust': [68], 'production': [69, 182], 'IFN-gamma': [71, 92, 218], 'gut,': [74], 'remarkable': [76], 'loss': [77], 'body': [79, 106], 'weight,': [80], 'as': [81, 83, 100, 130, 132], 'well': [82, 131], 'high': [84], 'rate': [85, 110], 'mortality': [87], '(60%).': [88], 'striking': [90], 'contrast,': [91], 'deficient': [93], 'did': [95], 'not': [96, 208], 'develop': [97], 'colitis,': [99, 227], 'indicated': [101, 180], 'by': [102, 189], 'maintenance': [104], 'weight': [107], 'survival': [109], '100%.': [112], 'Severe': [113], 'inflammation': [115], 'was': [116], 'demonstrated': [117], 'exclusively': [118], 'animals': [121], 'terms': [123], 'shortening': [126], 'elevation': [134], 'disease': [137], 'activity': [138, 142], 'index,': [139], 'myeloperoxidase': [140], '(MPO)': [141], 'serum': [144], 'haptoglobin': [145], 'level.': [146], 'Histological': [147], 'study': [148], 'intestine': [152, 204], 'revealed': [153], 'disruption': [154], 'mucosal': [156], 'epithelium': [157], 'massive': [159], 'infiltration': [160], 'cells,': [163], 'while': [164], 'organ': [166], 'from': [167], 'remained': [170], 'virtually': [171], 'normal': [172], 'appearance.': [174], 'Enzyme-linked': [175], 'immunosorbent': [176], 'assay': [177], '(ELISA)': [178], 'analyses': [179], 'abundant': [181], 'three': [184], 'chemokines,': [185], 'i.e.': [186], 'monokine': [187], 'induced': [188], 'interferon-gamma': [190], '(MIG),': [191], 'interferon-inducible': [192], 'protein': [193], '10': [194], '(IP-10)': [195], 'monocyte': [197], 'chemoattractant': [198], 'protein-1': [199], '(MCP-1),': [200], 'DSS-irritated': [203], 'mice.': [211], 'results': [214], 'demonstrate': [215], 'clearly': [216], 'that': [217], 'plays': [219], 'indispensable': [220], 'roles': [221], 'initiation': [224], 'DSS': [226], 'some': [229], 'chemokines': [230], 'are': [231], 'produced': [232], 'IFN-gamma-dependent': [235], 'fashion.': [236]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2022245027', 'counts_by_year': [{'year': 2024, 'cited_by_count': 26}, {'year': 2023, 'cited_by_count': 25}, {'year': 2022, 'cited_by_count': 21}, {'year': 2021, 'cited_by_count': 31}, {'year': 2020, 'cited_by_count': 20}, {'year': 2019, 'cited_by_count': 36}, {'year': 2018, 'cited_by_count': 31}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 28}, {'year': 2015, 'cited_by_count': 14}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 13}, {'year': 2012, 'cited_by_count': 13}], 'updated_date': '2025-01-06T09:59:46.401411', 'created_date': '2016-06-24'}