Title: Urinary excretion of hydroxyproline and proline during surgical stress
Abstract: The urinary excretion of hydroxyproline, proline, total nitrogen, and creatinine in six patients was analyzed for a period of six days prior to and eight days after surgery. In the postoperative period, an increased amount of proline and hydroxyproline is excreted which could be related to the protein catabolic reaction which takes place during surgical stress. The results obtained suggest that collagen participates in the metabolic changes which are produced as a result of the aforementioned phenomenon. The increased urinary excretion of proline, the metabolic precursor of hydroxyproline, could be related to the increased urinary excretion of total amino nitrogen and at the same time to a defect in the hydroxylation of proline.
Publication Year: 1968
Publication Date: 1968-06-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 2
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