Title: A Potential Role for Nerve Growth Factor in Regulating the Maturation of Inhibitory Neurotransmission
Abstract:Interneurons mediate inhibition in the CNS by releasing GABA, which hyperpolarizes postsynaptic neurons by promoting chloride entry through GABAA receptors. Low levels of intracellular chloride ([Cl−]...Interneurons mediate inhibition in the CNS by releasing GABA, which hyperpolarizes postsynaptic neurons by promoting chloride entry through GABAA receptors. Low levels of intracellular chloride ([Cl−]i) in postsynaptic neurons, maintained by the chloride exporter KCC2, are required for theRead More