Publication Information

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318, 350, 356, 395, 419, 423, 436, 475, 489, 505, 508, 567, 663, 744, 840, 1418, 1436, 1526, 1562, 1673, 1719, 1740, 1782, 1895, 1972, 1988, 2023, 2133, 2383, 2397, 2416, 2446, 2460, 2514, 2621, 2662, 2743, 2764, 2769, 2795, 2854, 2892, 2898, 2989, 3031, 3035, 3064, 3160, 3164, 3272, 3282, 3296, 3379, 3429, 3452, 3472, 3480, 3493, 3511, 3513, 3525, 3540, 3550, 3697, 3722, 3775, 3798, 3910, 3919, 3930, 3964, 4000, 4037, 4065, 4067, 4108, 4144, 4155, 4168, 4177, 4199, 4211, 4272, 4276, 4288, 4311, 4323, 4330, 4342], '25': [15, 241], 'kDa': [16, 242], '(SNAP25)': [17, 243], 'the': [19, 109, 121, 127, 161, 190, 207, 245, 335, 347, 353, 387, 416, 433, 503, 509, 558, 624, 838, 853, 1017, 1102, 1523, 1667, 1670, 1676, 1714, 1771, 1779, 1985, 2125, 2130, 2313, 2502, 2511, 2765, 2890, 2895, 3001, 3029, 3041, 3189, 3278, 3286, 3293, 3377, 3427, 3432, 3448, 3453, 3465, 3491, 3509, 3523, 3526, 3541, 3546, 3587, 3698, 3720, 3727, 3735, 3744, 3753, 3771, 3781, 3795, 3799, 3819, 3920, 3931, 3962, 3998, 4034, 4079, 4083, 4087, 4103, 4153, 4181, 4197, 4202, 4209, 4242, 4258, 4273, 4285, 4309, 4321, 4351], 'vesicle': [20, 246, 1104, 1458, 3300], 'SNARE': [21, 182, 223, 247, 408, 449, 659, 841, 1064, 1795, 2373, 2463], 'vesicle-associated': [23, 249, 452], '(VAMP)': [26, 252], 'are': [27, 45, 253, 271, 557, 615, 661, 1448, 1976], 'essential': [28, 173, 204, 254, 399, 430, 1725, 3966], 'for': [29, 120, 137, 164, 174, 206, 255, 346, 363, 390, 400, 432, 498, 562, 632, 1101, 1338, 1450, 1556, 1598, 1603, 1726, 1778, 1830, 1893, 2032, 2042, 2306, 2311, 2326, 2334, 2427, 2455, 2499, 2673, 2689, 2731, 2839, 3004, 3021, 3054, 3070, 3077, 3109, 3180, 3280, 3312, 3726, 3806, 3812, 3967, 4105], 'a': [30, 52, 90, 118, 133, 145, 256, 278, 316, 344, 359, 371, 472, 476, 565, 629, 745, 1335, 1451, 1681, 1888, 1896, 2505, 2519, 2525, 2536, 2542, 2560, 2569, 2579, 2611, 2663, 2903, 3032, 3309, 3531, 3601, 3740, 3749, 3924, 3928, 4218], 'late': [31, 62, 257, 288, 1452, 2766], 'Ca2+-dependent': [32, 148, 175, 218, 258, 374, 401, 444, 1059, 1201, 1422, 1453, 1524, 1685, 1727, 1790, 2619, 2767, 2942, 2959, 3146, 3695, 3824, 4035, 4127, 4228, 4286], 'step': [33, 63, 259, 289, 1454, 2768], 'in': [34, 64, 82, 126, 144, 212, 260, 290, 308, 352, 370, 438, 481, 748, 843, 1108, 1428, 1439, 1536, 1684, 1784, 1801, 1929, 1935, 1968, 2061, 2136, 2443, 2452, 2629, 2655, 2676, 2694, 2698, 2771, 2858, 2865, 2902, 3006, 3167, 3183, 3292, 3431, 3484, 3508, 3545, 3770, 3997, 4082, 4122, 4152, 4180, 4201, 4223, 4252, 4325, 4337, 4360], 'regulated': [35, 213, 261, 439, 1429, 1437, 1785, 2899], 'exocytosis,': [36, 115, 138, 262, 341, 364, 1527, 3283], 'but': [37, 95, 263, 321, 2056, 2966, 3520], 'their': [38, 264], 'precise': [39, 265, 1416], 'roles': [40, 266], 'regulation': [42, 129, 268, 355, 3295], 'by': [43, 100, 152, 269, 326, 378, 1021, 1745, 1884, 1982, 2000, 2010, 2015, 2051, 2071, 2146, 2153, 2169, 2225, 2265, 2297, 2318, 2320, 2377, 2438, 2466, 2550, 2589, 2651, 2684, 2740, 2846, 2861, 3044, 3066, 3274, 3470, 3498, 3984, 4045, 4053, 4166, 4187], 'Ca2+': [44, 102, 110, 128, 135, 191, 270, 328, 336, 354, 361, 417, 1336, 1748, 1960, 2041, 2863, 2893, 2947, 2964, 3005, 3050, 3062, 3151, 3158, 3294, 3310, 3430, 3473, 3489, 3521, 3554, 3572, 3604, 3776, 4001, 4080, 4093, 4106, 4169, 4236, 4303, 4324, 4361], 'poorly': [46, 272], 'understood.': [47, 273], 'Botulinum': [48, 274], 'neurotoxin': [49, 275, 463, 1515], '(BoNT)': [50, 276, 1516], 'E,': [51, 277], 'protease': [53, 279, 2707], 'that': [54, 202, 280, 428, 571, 622, 742, 837, 973, 1061, 1446, 1455, 1530, 1666, 1736, 1774, 1900, 2063, 2124, 2775, 2850, 2906, 3053, 3177, 3288, 3488, 3693, 4350, 4358], 'cleaves': [55, 72, 281, 298, 1550, 3081, 3114], 'SNAP25': [56, 73, 125, 143, 170, 211, 282, 299, 351, 369, 396, 437, 556, 1534, 1563, 1592, 1674, 1720, 1783, 2070, 2544, 2626, 2736, 2750, 2796, 2990, 3273, 3289, 3382, 3437, 3460, 3494, 3507, 3564, 3768, 3789, 3807, 3965, 3972, 3982, 4038, 4075, 4121, 4145, 4182, 4203, 4277, 4293], 'at': [57, 74, 283, 300, 1541, 1593, 1833, 1932, 2035, 2058, 2072, 2329, 2380, 2389, 2430, 2670, 2686, 2746, 2789, 2945, 2962, 2971, 2981, 3037, 3149, 3543, 3569, 3577, 4091], 'Arg180-Ile181,': [58, 284], 'completely': [59, 285, 1521, 2778, 4043], 'inhibits': [60, 286, 573], 'this': [61, 287, 490, 1717, 2840, 3168], 'PC12': [65, 291, 1798, 2137, 2772, 2909, 3170], 'cell': [66, 292, 2138, 2910, 3171], 'membranes,': [67, 293], 'whereas': [68, 156, 294, 382, 2782], 'BoNT': [69, 93, 97, 104, 153, 157, 194, 295, 319, 323, 330, 379, 383, 420, 1544, 1548, 1599, 1604, 1737, 1992, 2005, 2052, 2134, 2776, 2783, 2851, 2896, 2937, 2955, 2974, 2977, 2997, 3045, 3071, 3078, 3110, 3161, 3181, 3275, 3977, 3980, 4048, 4056, 4073, 4098, 4190, 4279, 4327, 4339], 'A,': [70, 296, 1545, 1993, 3396, 3444, 3476, 4159], 'which': [71, 116, 297, 342, 482, 1528, 1546, 2434, 3080, 3112, 4162], 'Gln197-Arg198,': [75, 301], 'is': [76, 215, 302, 441, 471, 485, 1056, 1721, 1742, 1787, 2047, 2122, 2129, 3174], 'only': [77, 303, 1553, 2057, 2786], 'partially': [78, 304, 1554, 1743, 4051], 'inhibitory.': [79, 305], 'difference': [81, 307, 2841], 'toxin': [83, 309, 1512, 1677, 2325, 3067, 3988, 4305], 'effectiveness': [84, 310], 'was': [85, 139, 150, 171, 311, 365, 376, 397, 1552, 1664, 1966, 2030, 2222, 2262, 2316, 2465, 2627, 2785, 2844, 2856, 2968, 3026, 3068, 3074, 3290, 3383, 3400, 3461, 3467, 3973, 4042, 4076, 4163, 4184, 4250], 'found': [86, 140, 312, 366, 3384], 'to': [87, 113, 141, 178, 216, 313, 339, 367, 404, 442, 855, 1016, 1330, 1432, 1539, 1723, 1788, 1962, 1984, 2039, 2049, 2068, 2450, 2497, 2532, 2541, 2565, 2573, 2583, 2625, 2724, 3013, 3176, 3306, 3385, 3439, 3458, 3506, 3530, 3558, 3563, 3599, 3810, 3917, 3992, 4112, 4133, 4292, 4314], 'result': [88, 314, 3030], 'from': [89, 315, 1442, 2556, 4146], 'reversal': [91, 192, 317, 418, 3063, 3159], 'A': [94, 105, 158, 195, 320, 331, 384, 421, 833, 1738, 2053, 2593, 2784, 2852, 2956, 2978, 2998, 3046, 3072, 3162, 3276, 3978, 4057, 4099, 4280, 4328, 4340], 'not': [96, 322, 2993, 3027, 3075, 3585, 3793], 'E': [98, 154, 324, 380, 1520, 1549, 1600, 1996, 2055, 2777, 2938, 2975, 4049, 4191, 4282], 'inhibition': [99, 196, 325, 422, 1739, 2135, 2853, 2897, 2967, 3043, 3065, 3163, 3182, 4066, 4088, 4329, 4341], 'elevated': [101, 327], 'concentrations.': [103, 329], 'treatment': [106, 159, 332, 385, 2022, 2939, 2957, 4046, 4054, 4100, 4188, 4306], 'essentially': [107, 333, 2999, 4101], 'increased': [108, 160, 334, 386, 3000, 3277, 3522, 4102], 'concentration': [111, 337, 4081, 4244], 'required': [112, 163, 338, 389, 631, 1449, 3557, 3725], 'activate': [114, 340], 'suggested': [117, 343, 1332, 2845], 'role': [119, 205, 345, 431, 1100, 1333, 1417, 1683, 1777], 'C': [122, 167, 208, 348, 393, 434, 1671, 1780, 4274], 'terminus': [123, 168, 209, 349, 394, 435, 1672, 1781, 4275], 'exocytosis.': [131, 357, 3297], 'Synaptotagmin,': [132, 358], 'proposed': [134, 360, 3305], 'sensor': [136, 362, 1337, 3311], 'bind': [142, 368, 3386], 'Ca2+-stimulated': [146, 372, 3728, 3786, 4175], 'manner.': [147, 373], 'binding': [149, 177, 375, 403, 2335, 2620, 2630, 2732, 3433, 3438, 3451, 3466, 3482, 3505, 3542, 3562, 3769, 3825, 3908, 4070, 4084, 4111, 4240, 4255, 4287, 4310], 'abolished': [151, 377, 4044], 'treatment,': [155, 381], 'Ca2+concentration': [162, 388], 'binding.': [165, 391], 'also': [172, 398, 3462], 'synaptotagmin': [176, 221, 402, 447, 1106, 1419, 1793, 2158, 2220, 2423, 2515, 2623, 3302, 3371, 3390, 3440, 3454, 3496, 3560, 3723, 3813, 3911, 3968, 3995, 4040, 4068, 4109, 4118, 4156, 4178, 4221, 4238, 4290, 4343, 4356], 'SNAP25·syntaxin': [179, 405], 'SNAP25·syntaxin·VAMP': [181, 407], 'complexes.': [183, 225, 409, 451, 1797], 'These': [184, 410, 613, 3142, 3804], 'results': [185, 411, 1772, 3805], 'clarify': [186, 412], 'classical': [187, 413, 1734], 'observations': [188, 414, 1735], 'on': [189, 415, 2641, 2760, 2894, 4116, 4230], 'neurosecretion,': [198, 424], 'they': [200, 426], 'suggest': [201, 427, 1773], 'an': [203, 429, 1098, 1775, 2677, 3387, 4213], 'exocytosis': [214, 440, 1339, 1438, 1786, 2770, 3008, 3036, 3313, 4331], 'mediate': [217, 443, 623, 977, 1789, 3694], 'interactions': [219, 445, 850, 1202, 1423, 1728, 1791, 3593, 3787, 3815, 4128, 4345], 'between': [220, 446, 1675, 1792, 2842, 4129, 4320], 'botulinum': [462, 1514], 'glutathione': [464, 2305], 'S-transferase': [465, 2141], '3-(cyclohexylamino)propanesulfonic': [466], 'acid': [467], 'Regulated': [468], 'neurotransmitter': [469], 'secretion': [470, 2043, 2901, 3165], 'specialized': [473], 'version': [474], 'general': [477], 'fusion': [479, 484, 501, 510, 634, 858, 983, 1019, 1466, 1558, 1687, 2143, 2293, 3783], 'mechanism': [480], 'exocytotic': [483], 'strictly': [486], 'Ca2+-regulated.': [487], 'Studies': [488, 962, 1435, 2763], 'process': [491], 'have': [492, 1096, 4363], 'yielded': [493], 'insights': [494], 'into': [495, 665], 'universal': [496], 'mechanisms': [497], 'intracellular': [499], 'identity': [504], 'core': [506], 'components': [507], 'machinery': [511], '(1.Sudhof': [512, 1067, 1340, 3314], 'T.C.': [513, 703, 1068, 1124, 1216, 1235, 1297, 1312, 1341, 1364, 1382, 1400, 1646, 2480, 3315, 3337, 3355, 3656, 3671, 3701, 3874, 3889, 4377, 4392], 'Nature.': [514, 649, 824, 891, 904, 1069, 1298, 1342, 3099, 3316, 3657, 3875, 4378], '1995;': [515, 1070, 1239, 1261, 1299, 1316, 1343, 1404, 2244, 2279, 3129, 3317, 3620, 3658, 3675, 3838, 3876, 3893, 4379, 4396], '375:': [516, 1071, 1300, 1344, 3318, 3659, 3877, 4380], '645-653Crossref': [517, 1072, 1345, 3319], 'PubMed': [518, 532, 548, 588, 608, 653, 687, 711, 737, 770, 788, 811, 828, 878, 895, 908, 927, 957, 1009, 1050, 1073, 1089, 1132, 1150, 1173, 1193, 1223, 1245, 1269, 1283, 1302, 1324, 1346, 1372, 1389, 1410, 1486, 1506, 1583, 1629, 1660, 1708, 1765, 1861, 1877, 1920, 2090, 2116, 2186, 2212, 2252, 2287, 2488, 2816, 2832, 2882, 2932, 3103, 3137, 3212, 3229, 3249, 3265, 3320, 3345, 3362, 3421, 3628, 3642, 3661, 3683, 3713, 3846, 3860, 3879, 3901, 3955, 4027, 4382], 'Scopus': [519, 533, 549, 589, 609, 654, 688, 712, 738, 771, 789, 812, 829, 879, 896, 909, 928, 958, 1010, 1051, 1074, 1090, 1133, 1151, 1174, 1194, 1224, 1246, 1270, 1303, 1325, 1347, 1373, 1390, 1411, 1487, 1507, 1584, 1630, 1709, 1766, 1862, 1878, 1921, 2091, 2117, 2187, 2213, 2253, 2288, 2489, 2817, 2833, 2883, 2933, 3104, 3138, 3213, 3230, 3266, 3321, 3346, 3363, 3422, 3629, 3662, 3684, 3714, 3847, 3880, 3902, 3956, 4028, 4383], '(1770)': [520, 1075, 1348, 3322], 'Google': [521, 535, 551, 591, 611, 656, 690, 714, 740, 773, 791, 814, 831, 881, 898, 911, 930, 960, 1012, 1053, 1076, 1092, 1135, 1153, 1176, 1196, 1226, 1248, 1272, 1284, 1305, 1327, 1349, 1375, 1392, 1413, 1489, 1509, 1586, 1632, 1661, 1711, 1768, 1864, 1880, 1923, 2093, 2119, 2189, 2215, 2255, 2290, 2491, 2819, 2835, 2885, 2935, 3106, 3140, 3215, 3232, 3250, 3268, 3323, 3348, 3365, 3424, 3631, 3643, 3664, 3686, 3716, 3849, 3861, 3882, 3904, 3958, 4030, 4385], 'Scholar,': [522, 536, 592, 691, 715, 774, 792, 815, 882, 899, 912, 931, 1077, 1136, 1154, 1177, 1227, 1249, 1273, 1285, 1306, 1350, 1376, 1490, 1865, 2094, 2190, 2820, 3216, 3233, 3251, 3349, 3632, 3644, 3665, 3850, 3862, 3883, 4386], '2.Calakos': [523], 'N.': [524, 1212, 1295, 1378, 2198, 3351, 3654, 3872, 4375], 'Scheller': [525, 676, 777, 1276, 2172, 2177, 2203, 3122, 3635, 3853], 'R.H.': [526, 677, 778, 1277, 2178, 2204, 3123, 3636, 3854], 'Physiol.': [527, 3224], 'Rev.': [528], '1996;': [529, 1280, 1478, 1575, 1700, 1853, 2808, 3639, 3705, 3857], '76:': [530], '1-29Crossref': [531], '(312)': [534], '3.Martin': [537], 'T.F.J.': [538, 1474, 1492, 1571, 1696, 1849, 1869, 1906, 2804, 2824, 2918], 'Trends': [539, 579, 599], 'Cell': [540, 600], 'Biol.': [541, 601, 727, 807, 923, 1259, 1314, 1476, 1496, 1573, 1652, 1698, 1851, 1910, 2242, 2277, 2806, 2922, 3127, 3618, 3673, 3836, 3891, 4394], '1997;': [542, 729, 762, 780, 870, 1498, 1912, 2087, 2924, 3246, 3418, 4024], '7:': [543], '271-276Abstract': [544], 'Full': [545, 585, 605, 684, 732, 734, 765, 767, 783, 785, 873, 875, 952, 954, 1004, 1006, 1045, 1047, 1084, 1086, 1129, 1147, 1190, 1242, 1264, 1266, 1319, 1321, 1369, 1407, 1481, 1483, 1501, 1503, 1578, 1580, 1657, 1703, 1705, 1762, 1856, 1858, 1915, 1917, 2183, 2209, 2247, 2249, 2282, 2284, 2811, 2813, 2879, 2927, 2929, 3132, 3134, 3209, 3342, 3623, 3625, 3678, 3680, 3708, 3710, 3841, 3843, 3896, 3898, 3950, 3952], 'Text': [546, 586, 606, 685, 733, 735, 766, 768, 784, 786, 874, 876, 953, 955, 1005, 1007, 1046, 1048, 1085, 1087, 1130, 1148, 1191, 1243, 1265, 1267, 1320, 1322, 1370, 1408, 1482, 1484, 1502, 1504, 1579, 1581, 1658, 1704, 1706, 1763, 1857, 1859, 1916, 1918, 2184, 2210, 2248, 2250, 2283, 2285, 2812, 2814, 2880, 2928, 2930, 3133, 3135, 3210, 3343, 3624, 3626, 3679, 3681, 3709, 3711, 3842, 3844, 3897, 3899, 3951, 3953], 'PDF': [547, 587, 607, 686, 736, 769, 787, 877, 956, 1008, 1049, 1088, 1131, 1149, 1192, 1244, 1268, 1323, 1371, 1409, 1485, 1505, 1582, 1659, 1707, 1764, 1860, 1919, 2185, 2211, 2251, 2286, 2815, 2881, 2931, 3136, 3211, 3344, 3627, 3682, 3712, 3845, 3900, 3954], '(123)': [550], 'Scholar).': [552, 612, 657, 832, 961, 1013, 1093, 1197, 1414, 1510, 1587, 1712, 1769, 1924, 2120, 2216, 2256, 2291, 2492, 2836, 2886, 2936, 3141, 3269, 3425, 3687, 3717, 3905, 3959, 4031], 'VAMP,1': [553], 'syntaxin,': [554, 1532, 2385], 'neural': [559], 'substrates': [561], 'clostridial': [563], 'neurotoxins,': [564], 'family': [566], 'highly': [568], 'selective': [569], 'proteases': [570], 'potently': [572], 'neurosecretion': [574, 1055, 1110, 1430, 1741, 2855], '(4.Montecucco': [575], 'C.': [576, 800, 1118, 1287, 1308, 1358, 1623, 2084, 2102, 3098, 3125, 3331, 3646, 3667, 3864, 3885, 4367, 4388], 'Schiavo': [577], 'G.': [578, 1609, 2080, 3084, 3117, 3404, 3406, 4010, 4012], 'Biochem.': [580], 'Sci.': [581, 1166, 1758, 2875, 3205, 3414, 4020], '1993;': [582, 650, 681, 1144, 1187, 1626, 2180], '18:': [583], '324-327Abstract': [584], '(217)': [590], '5.Niemann': [593], 'H.': [594, 642, 695, 705, 719, 756, 864, 1650, 1751, 2108, 2171, 2472, 2482, 2868, 3198, 3257], 'Blasi': [595, 1637], 'J.': [596, 707, 726, 1258, 1278, 1313, 1475, 1495, 1572, 1617, 1638, 1651, 1697, 1756, 1850, 1872, 1909, 2111, 2192, 2236, 2241, 2276, 2484, 2805, 2827, 2873, 2921, 3126, 3203, 3244, 3617, 3637, 3672, 3703, 3835, 3855, 3890, 3937, 4393], 'Jahn': [597, 722, 757, 820, 865, 887, 1217, 1256, 1383, 1647, 2274, 3356, 3615, 3833], 'R.': [598, 723, 754, 758, 821, 862, 866, 888, 901, 1218, 1257, 1384, 1648, 1867, 2002, 2078, 2170, 2275, 2590, 2822, 3357, 3616, 3834], '1994;': [602, 708, 1126, 1170, 1366, 1654, 2206, 2485, 3339], '4:': [603], '179-183Abstract': [604], '(293)': [610], 'receptors': [620], '(SNAREs)': [621], 'association': [626], 'ofN-ethylmaleimide-sensitive': [627], 'factor,': [628], '(6.Sollner': [635], 'T.': [636, 671, 693, 699, 933, 985, 1026, 1636, 2110, 2234, 2470, 2476, 3253, 3255], 'Whiteheart': [637, 674], 'S.W.': [638, 675], 'Brunner': [639], 'M.': [640, 941, 993, 1034, 1112, 1158, 1160, 1352, 2100, 2226, 2232, 2238, 2551, 3235, 3325], 'Erdjument-Bromage': [641], 'Geromanos': [643], 'S.': [644, 697, 1168, 1255, 1640, 1753, 1755, 2011, 2104, 2106, 2273, 2474, 2870, 2872, 3200, 3202, 3220, 3416, 3614, 3832, 4022], 'Tempst': [645], 'P.': [646, 2076, 3094], 'Rothman': [647, 678, 946, 998, 1039, 3407, 4013], 'J.E.': [648, 679, 947, 999, 1040, 3408, 4014], '362:': [651], '318-324Crossref': [652], '(2637)': [655], 'capable': [662], 'assembling': [664], 'extremely': [666], 'stable': [667], 'heterotrimeric': [668, 2462], 'complexes': [669, 842, 975, 2374, 2464], '(7.Sollner': [670], 'Bennett': [672, 803, 2201, 3120], 'M.K.': [673, 804, 2202, 3121], 'Cell.': [680, 761, 869, 948, 1000, 1041, 1125, 1143, 1186, 1238, 1365, 1403, 2179, 3338], '75:': [682], '409-418Abstract': [683], '(1586)': [689], '8.Hayashi': [692], 'McMahon': [694, 2471], 'Yamasaki': [696, 1639, 2473], 'Binz': [698, 2109, 2475, 3254], 'Hata': [700, 2477], 'Y.': [701, 1114, 1275, 1354, 2478, 3327, 3634, 3852], 'Sudhof': [702, 1123, 1215, 1234, 1296, 1311, 1363, 1381, 1399, 1645, 2479, 3336, 3354, 3655, 3670, 3873, 3888, 4376, 4391], 'Niemann': [704, 1649, 2481, 3256], 'EMBO': [706, 2483], '13:': [709, 2207, 2486], '5051-5061Crossref': [710, 2487], '(664)': [713, 2490], '9.Fasshauer': [716], 'D.': [717, 819, 886, 3939], 'Otto': [718], 'Eliason': [720], 'W.K.': [721], 'Brunger': [724, 822, 889, 919], 'A.T.': [725, 823, 890, 920], 'Chem.': [728, 1260, 1315, 1477, 1497, 1574, 1653, 1699, 1852, 1911, 2243, 2278, 2807, 2923, 3128, 3619, 3674, 3837, 3892, 4395], '272:': [730, 1499, 1913, 2925], '28036-28041Abstract': [731], '(281)': [739], 'Scholar)': [741, 1328, 1881], 'consist': [743, 3918], 'four-helix': [746], 'bundle': [747], 'parallel': [749], 'alignment': [750], '(10.Hanson': [751, 859], 'P.I.': [752, 860, 903, 1253, 2271, 3612, 3830], 'Roth': [753, 861], 'Morisaki': [755, 863], 'Heuser': [759, 867], 'J.R.': [760, 868], '90:': [763, 871], '523-535Abstract': [764, 872], '(671)': [772, 880], '11.Lin': [775], 'R.C.': [776], 'Neuron.': [779, 1080, 2205, 3704, 3946], '19:': [781], '1087-1094Abstract': [782], '(274)': [790], '12.Poirier': [793], 'M.A.': [794], 'Xiao': [795], 'W.': [796], 'Macosko': [797], 'J.C.': [798], 'Chan': [799], 'Shin': [801], 'Y.-K.': [802], 'Nature': [805, 921, 3260], 'Struct.': [806, 922], '1998;': [808, 825, 892, 905, 949, 1001, 1042, 1081, 3262], '5:': [809], '765-769Crossref': [810], '(419)': [813], '13.Sutton': [816, 883], 'R.B.': [817, 884, 1229, 1394], 'Fasshauer': [818, 885, 3938], '395:': [826, 893], '347-353Crossref': [827, 894], '(1932)': [830, 897], 'current': [834], 'hypothesis': [835], 'suggests': [836], 'formation': [839, 1066], 'transacross': [844], 'apposing': [845], 'membranes': [846, 2912], 'promotes': [847], 'intimate': [848], 'bilayer': [849, 978], 'provides': [852], 'energy': [854], 'drive': [856], '14.Jahn': [900], 'Hanson': [902, 1252, 2270, 3611, 3829], '393:': [906], '14-15Crossref': [907], '(79)': [910], '15.Fiebig': [913], 'K.M.': [914], 'Rice': [915], 'L.M.': [916], 'Pollock': [917], 'E.': [918, 1079, 1644, 2266, 3259, 3981], '1999;': [924, 2113, 3947], '6:': [925], '117-123Crossref': [926], '(237)': [929], '16.Weber': [932], 'Zemelman': [934, 986, 1027], 'B.V.': [935, 987, 1028], 'McNew': [936, 988, 1029], 'J.A.': [937, 989, 1030, 1470, 1494, 1567, 1692, 1845, 1908, 2800, 2920], 'Westermann': [938, 990, 1031], 'B.': [939, 991, 1032, 1289, 2001, 3088, 3648, 3866, 4369], 'Gmachl': [940, 992, 1033], 'Parlati': [942, 994, 1035], 'F.': [943, 995, 1036, 1619, 3086], 'Sollner': [944, 996, 1037, 3409, 4015], 'T.H.': [945, 997, 1038, 3410, 4016], '92:': [950, 1002, 1043], '759-772Abstract': [951, 1003, 1044], '(2021)': [959, 1011, 1052], 'with': [963, 1203, 1209, 1424, 1729, 1807, 1818, 2017, 2322, 2402, 2420, 2501, 2510, 2524, 2610, 2632, 2638, 2706, 2749, 2996, 3048, 3374, 3495, 3565, 3594, 3730, 3788, 3816, 3923, 3976, 3986, 3994, 4039, 4047, 4055, 4072, 4086, 4136, 4189, 4257, 4267, 4278], 'donor': [964], 'acceptor': [966], 'proteoliposomes': [967], 'containing': [968, 2340, 2394, 2413, 2913, 3743, 3752], 'VAMP': [969, 2165, 2387, 2528, 2584, 3082], 'or': [970, 1426, 1540, 2060, 2308, 2351, 2363, 2386, 2408, 2517, 2553, 2578, 2594, 2728, 2733, 2756, 3108, 3192, 3548, 3748, 3773, 3979, 4281], 'syntaxin/SNAP25': [971], 'indicate': [972], 'trans-SNARE': [974], 'can': [976], 'phospholipid': [979], 'mixing': [980], 'possibly': [982], '(16.Weber': [984, 1025], 'In': [1014, 1713, 2953, 3376, 3447, 3779, 4032, 4217], 'contrast': [1015], 'slow': [1018], 'mediated': [1020], 'reconstituted': [1022], 'SNAREsin': [1023], 'vitro': [1024], 'Scholar),': [1054, 1662, 3107, 3366], 'rapid': [1057, 1109], 'suggesting': [1060], 'Ca2+may': [1062], 'regulate': [1063], 'complex': [1065, 2407, 3185], '17.Neher': [1078], '20:': [1082], '389-399Abstract': [1083], '(856)': [1091], 'Genetic': [1094], 'studies': [1095, 2336, 2631, 2848, 4115, 4256], 'established': [1097], 'important': [1099, 1776], 'Ca2+-binding': [1103, 3299], 'I': [1107, 1199, 2159, 2516, 2624, 3391, 3441, 3455, 3497, 3504, 3561, 3592, 3724, 3814, 3912, 3969, 3996, 4041, 4069, 4110, 4119, 4157, 4179, 4222, 4239, 4291], '(18.Geppert': [1111], 'Goda': [1113, 1353, 3326], 'Hammer': [1115, 1355, 3328], 'R.E.': [1116, 1356, 3329], 'Li': [1117, 1357, 3330], 'Rosahl': [1119, 1359, 3332], 'T.W.': [1120, 1360, 3333], 'Stevens': [1121, 1361, 3334], 'C.F.': [1122, 1362, 3335], '79:': [1127, 1367, 3340], '717-727Abstract': [1128, 1368, 3341], '(1223)': [1134, 1374, 3347], '19.DiAntonio': [1137], 'A.': [1138, 1169, 1468, 1565, 1611, 1642, 1690, 1843, 2798, 3417, 4023], 'Parfitt': [1139], 'K.D.': [1140], 'Schwarz': [1141], 'T.L.': [1142], '73:': [1145, 1188], '1281-1290Abstract': [1146], '(218)': [1152], '20.Littleton': [1155], 'J.T.': [1156], 'Stern': [1157], 'Perin': [1159], 'Bellen': [1161], 'H.J.': [1162], 'Proc.': [1163, 3411, 4017], 'Natl.': [1164, 3412, 4018], 'Acad.': [1165, 3413, 4019], 'U.': [1167, 3415, 4021], '91:': [1171], '10888-10892Crossref': [1172], '(248)': [1175], '21.Nonet': [1178], 'M.L.': [1179], 'Grundahl': [1180], 'K.': [1181, 2098, 2229, 2240], 'Meyer': [1182], 'B.J.': [1183], 'Rand': [1184], 'J.B.': [1185], '1291-1305Abstract': [1189], '(459)': [1195], 'Synaptotagmin': [1198, 3503, 3591, 3688], 'exhibits': [1200], 'acidic': [1204], 'phospholipids': [1205, 1425], 'as': [1206, 1208, 1334, 1839, 1978, 2604, 2643, 3188, 3308, 3399, 3759, 4006, 4249], 'well': [1207], '(22.Brose': [1211], 'Petrenko': [1213, 1379, 3352], 'A.G.': [1214, 1380, 3353], 'Science.': [1219, 1385, 3358], '1992;': [1220, 1386, 3100, 3359], '256:': [1221, 1387, 3360], '1021-1025Crossref': [1222, 1388, 3361], '(772)': [1225, 1391, 3364], '23.Sutton': [1228], 'Davletov': [1230, 1309, 1395, 3668, 3886, 4389], 'B.A.': [1231, 1310, 1396, 3669, 3887, 4390], 'Berghuis': [1232, 1397], 'A.M.': [1233, 1398], 'Sprang': [1236, 1401], 'S.R.': [1237, 1402], '80:': [1240, 1405], '929-938Abstract': [1241, 1406], '(606)': [1247, 1412], '24.Chapman': [1250], 'E.R.': [1251, 2269, 3610, 3828, 3945], 'An': [1254, 2272, 2837, 3613, 3831], '270:': [1262, 1317, 2245, 2280, 3130, 3621, 3676, 3839, 3894, 4397], '23667-23671Abstract': [1263, 2281, 3622, 3840], '(323)': [1271, 2289, 3630, 3848], '25.Kee': [1274, 3633, 3851], 'Neurosci.': [1279, 3245, 3261, 3638, 3856], '16:': [1281, 3640, 3858], '1975-1981Crossref': [1282, 3641, 3859], '26.Li': [1286, 3645, 3863], 'Ullrich': [1288, 3647, 3865, 4368], 'Zhang': [1290, 3649, 3867, 4370], 'J.Z.': [1291, 3650, 3868, 4371], 'Anderson': [1292, 3651, 3869, 4372], 'R.G.W.': [1293, 3652, 3870, 4373], 'Brose': [1294, 3653, 3871, 4374], '594-599Crossref': [1301, 3660, 3878, 4381], '(541)': [1304, 3663, 3881, 4384], '27.Li': [1307, 3666, 3884, 4387], '24898-24902Abstract': [1318, 3677, 3895], '(128)': [1326, 3685, 3903], 'leading': [1329], 'its': [1331, 1421, 3990], '18.Geppert': [1351], '22.Brose': [1377, 3350], 'Scholar,23.Sutton': [1393], 'remains': [1431], 'be': [1433, 1724], 'determined.': [1434], 'preparations': [1441, 2025], 'neuroendocrine': [1443], 'cells': [1444, 1799, 2773, 3196], 'demonstrated': [1445], 'SNAREs': [1447], 'occurs': [1456], 'after': [1457], 'docking': [1459], 'ATP-dependent': [1461], 'priming': [1462], 'immediately': [1464], 'before': [1465], '(28.Banerjee': [1467, 1564, 1689, 1842, 2797], 'Kowalchyk': [1469, 1493, 1566, 1691, 1844, 1907, 2799, 2919], 'DasGupta': [1471, 1568, 1612, 1693, 1846, 1870, 2801, 2825, 3095, 3221], 'B.R.': [1472, 1569, 1613, 1694, 1847, 1871, 2802, 2826, 3096, 3222], 'Martin': [1473, 1570, 1695, 1848, 1868, 2803, 2823], '271:': [1479, 1576, 1701, 1854, 2809], '20227-20230Abstract': [1480, 1577, 1702, 1855, 2810], '(143)': [1488, 1585, 1710, 1863, 2818], '29.Martin': [1491], '14447-14453Abstract': [1500, 1914, 2926], '(71)': [1508, 1922, 2934], 'Tetanus': [1511], 'B,': [1517, 1994, 3079, 4263, 4296], 'C1,': [1518, 3111], 'inhibited': [1522, 2779, 2941, 2958, 3145, 4052], 'triggering': [1525, 3007], 'implied': [1529], 'VAMP,': [1531], 'participate': [1535], 'steps': [1537], 'close': [1538], 'fusion.': [1542], 'Paradoxically': [1543], 'like': [1547], 'SNAP25,': [1551, 2384, 2405, 3731], 'inhibitory': [1555, 2791], 'triggered': [1557], 'despite': [1559, 2792], 'efficient': [1560], 'proteolysis': [1561, 2050, 2991], 'Because': [1588, 3270], 'these': [1589, 4130], 'toxins': [1590, 2843, 3143], 'cleave': [1591, 2069], 'distinct': [1594, 1682], 'C-terminal': [1595, 2543], 'sites': [1596, 1679], '(Arg180-Ile181': [1597], 'Gln197-Arg198': [1602], 'A;': [1605], 'see': [1606], 'Refs.': [1607], '30.Schiavo': [1608], 'Santucci': [1610], 'Mehta': [1614], 'P.P.': [1615], 'Jontes': [1616], 'Fenfenati': [1618], 'Wilson': [1620, 2081, 2552], 'M.C.': [1621, 2082], 'Montecucco': [1622, 2083, 3097, 3124], 'FEBS': [1624, 2085], 'Lett.': [1625, 2086], '335:': [1627], '99-103Crossref': [1628], '(379)': [1631], 'Scholar': [1633], '31.Binz': [1635], 'Baumeister': [1641], 'Link': [1643], '269:': [1655], '1617-1620Abstract': [1656], 'it': [1663, 3791], 'inferred': [1665], 'domain': [1668, 1718, 3393, 3457, 3738, 3746, 3755, 3802, 3821, 3909, 3922, 3933], 'within': [1669], 'cleavage': [1678, 2310, 2794, 3271, 3985], 'plays': [1680], 'events': [1688], 'present': [1715, 2980], 'study,': [1716], 'revealed': [1722, 4126], 'synaptotagmin.': [1730], 'This': [1731, 3024], 'finding': [1732], 'clarifies': [1733], 'reversed': [1744, 2860], 'elevating': [1746, 2862], 'neuronal': [1747], 'levels': [1749, 2864], '(32.Lundh': [1750, 2867, 3197], 'Leander': [1752, 2869, 3199], 'Thesleff': [1754, 2871, 3201, 3219], 'Neurol.': [1757, 2874, 3204], '1977;': [1759, 2876, 3206], '32:': [1760, 2877, 3207], '29-43Abstract': [1761, 2878, 3208], '(152)': [1767, 2884, 3214], 'Moreover,': [1770], 'grown': [1800], "Dulbecco's": [1802], 'modified': [1803], 'culture': [1804], 'medium': [1805], 'supplemented': [1806], '5%': [1808, 1812], 'horse': [1809], 'serum': [1810, 1815, 1953, 2361, 2534], 'iron-supplemented': [1813], 'calf': [1814], 'were': [1816, 1837, 1927, 2013, 2149, 2166, 2295, 2375, 2400, 2418, 2426, 2436, 2495, 2602, 2608, 2649, 2682, 2722, 2738, 2979, 3556, 3596, 3757, 3808, 4317], 'incubated': [1817, 2401, 2419, 2637], '0.5': [1819, 1826, 2421], 'μCi/ml': [1820], '[3H]norepinephrine': [1821, 1989], '(Amersham': [1822, 2300], 'Pharmacia': [1823, 2301], 'Biotech)': [1824, 2302], 'plus': [1825, 3927], 'mm': [1827, 2019, 2349, 2353, 2710, 2726], 'sodium': [1828], 'ascorbate': [1829], '16': [1831], 'h': [1832, 2328, 2429], '37': [1834], 'oC.': [1835], 'Cells': [1836], 'washed': [1838, 2441], 'described': [1840, 2467, 2644], 'previously': [1841, 3179, 3401, 3597, 4007], '33.Lomneth': [1866, 2821], 'Neurochem.': [1873, 2112, 2828], '1991;': [1874, 2829], '57:': [1875, 2830], '1413-1421Crossref': [1876, 2831], '(57)': [1879, 2834], 'homogenized': [1883], 'multiple': [1885], 'passes': [1886], 'through': [1887], 'stainless': [1889], 'steel': [1890], 'ball': [1891], 'homogenizer': [1892], 'preparation': [1894, 3173], 'fraction': [1899], 'contains': [1901, 3689], 'docked': [1902, 2914], 'dense-core': [1903, 2915], 'vesicles': [1904, 2916], '(29.Martin': [1905, 2917], 'Secretion': [1925], 'assays': [1926], 'conducted': [1928, 2031, 2739], '5-min': [1930], 'incubations': [1931, 2062], '30': [1933, 2036], 'oC': [1934, 2037, 2382, 2432, 2748], '0.05': [1936, 2699], 'm': [1937, 1942, 1949, 1956, 2342, 2657, 2700], 'HEPES,': [1938, 2343, 2701], 'pH': [1939, 2344, 2702], '7.2,': [1940, 2345, 2703], '0.12': [1941], 'potassium': [1943], 'glutamate,': [1944], '0.02': [1945, 2341], 'mpotassium': [1946], 'acetate,': [1947], '0.002': [1948, 1955], 'EGTA,': [1950, 2354], '0.1%': [1951], 'bovine': [1952, 2360, 2533], 'albumin,': [1954, 2535], 'MgATP,': [1957], 'free': [1959], 'adjusted': [1961, 2723], 'indicated': [1963], 'values.': [1964], '[3H]Norepinephrine': [1965], 'detected': [1967], 'supernatants': [1969], 'following': [1970, 2433, 2503], 'centrifugation': [1971, 2439, 2685], 'reaction': [1973, 3434, 4085], 'mixtures.': [1974], 'Results': [1975], 'plotted': [1977], 'percent': [1979, 3042], 'norepinephrine': [1980, 2900, 2943, 2960, 3147], 'release': [1981, 2944, 2961, 3148], 'normalization': [1983], 'total': [1986], 'content': [1987], 'per': [1990], 'incubation.': [1991], 'holotoxins': [1997], '(generously': [1998, 2008], 'provided': [1999, 2009, 2168, 2224, 2264, 2549, 2588], 'DasGupta)': [2003], 'C1': [2006], 'holotoxin': [2007], 'Kozaki)': [2012], 'activated': [2014], 'preincubation': [2016], '5': [2018, 2390], 'dithiothreitol.': [2020], 'Toxin': [2021], '(at': [2026], '1–100': [2027], 'nm': [2028], 'BoNT)': [2029], '3': [2033, 4059, 4096, 4171, 4269, 4347], 'min': [2034, 2675, 2691], 'prior': [2038, 2449], 'adding': [2040], 'incubations.': [2044], 'Mouse': [2045], 'SNAP23': [2046, 2127], 'susceptible': [2048], 'concentrations': [2059, 2948, 2984, 3051, 3152, 3555, 4094], 'exceed': [2064], 'those': [2065, 3811, 4134], 'used': [2066, 2603, 3758], 'here': [2067], 'least': [2073], '1000-fold': [2074], '(34.Washbourne': [2075], 'Pellizzari': [2077], 'Baldini': [2079], '418:': [2088], '1-5Crossref': [2089], '(117)': [2092], '35.Vaidyanathan': [2095], 'V.V.': [2096], 'Yoshino': [2097], 'Jahnz': [2099], 'Dorries': [2101], 'Bade': [2103], 'Nauenburg': [2105], 'Neimann': [2107], '72:': [2114, 2181], '327-337Crossref': [2115], '(189)': [2118], 'It': [2121], 'unlikely': [2123], 'rat': [2126, 2633, 2653, 4147], 'functional': [2131], 'target': [2132], 'membranes.': [2139], 'Glutathione': [2140], '(GST)': [2142], 'encoded': [2145], 'pGEX': [2147], 'vectors': [2148], 'produced': [2150], 'inEscherichia': [2151], 'coli': [2152], 'standard': [2154], 'methods.': [2155], 'Vectors': [2156], 'encoding': [2157, 2219, 2259], 'C2AB,': [2160], 'C2A,': [2161], 'C2B,': [2162], 'SNAP25B,': [2163], 'kindly': [2167, 2223, 2263], '(36.Elferink': [2173], 'L.A.': [2174], 'Peterson': [2175], 'M.R.': [2176], '153-159Abstract': [2182], '(209)': [2188], '37.Pevsner': [2191], 'Hsu': [2193], 'S.-C.': [2194], 'Braun': [2195], 'J.E.A.': [2196], 'Calakos': [2197], 'Ting': [2199], 'A.E.': [2200], '353-361Abstract': [2208], '(525)': [2214], 'vector': [2218, 2258], 'III': [2221], 'Fukuda': [2227], 'Mikoshiba': [2230, 2239], '(38.Fukuda': [2231], 'Kojima': [2233], 'Aruga': [2235], 'Niinobe': [2237], '26523-26527Abstract': [2246], '(162)': [2254], '1A': [2261], 'Chapman': [2267, 3944], '(24.Chapman': [2268, 3609, 3827], 'GST': [2292], 'purified': [2296, 2908, 3169], 'glutathione-agarose': [2298, 2642], 'chromatography': [2299], 'using': [2303, 2616, 2659], 'either': [2304, 3987], 'elution': [2307], 'thrombin': [2309], 'removing': [2312], 'GST.': [2314], 'GST-SNAP25': [2315, 2417, 2566, 2639, 4232], 'cleaved': [2317, 3975], 'BoNTs': [2319, 3056], 'incubation': [2321, 2379, 2742], '∼1': [2323], 'μm': [2324, 2404, 2422, 3534, 3571], '1': [2327, 2348, 2403, 2428, 2575, 2725, 2729, 3578], 'room': [2330], 'temperature.': [2331], 'Standard': [2332], 'conditions': [2333], 'employed': [2337], '200-μl': [2338], 'reactions': [2339], '0.15m': [2346], 'KCl,': [2347], 'CaCl2': [2350], '2': [2352, 2674, 2713, 3395, 3443, 3475, 3501, 3536], '0.5%': [2355], 'Triton': [2356, 2696], 'X-100,': [2357], '2.5%': [2359], 'albumin': [2362], '1%': [2364, 2695], 'cold': [2365], 'fish': [2366], 'skin': [2367], 'gelatin': [2368], '(Sigma).': [2369], 'Binary': [2370], 'ternary': [2372, 2409], 'formed': [2376], 'overnight': [2378, 2741], '4': [2381, 2431, 2747, 4234, 4262, 4295], 'each': [2388], 'μm.': [2391], 'Glutathione-agarose': [2392, 2411], 'beads': [2393, 2412, 2435], '5–10': [2395, 2414], 'μg': [2396, 2415], 'GST-synaptotagmin': [2398], '(C2AB)': [2399], 'binary': [2406, 4253], 'complex.': [2410], '(C2AB).': [2424, 3803], 'Incubations': [2425], 'recovered': [2437], 'twice': [2442], '400': [2444], 'μl': [2445], 'assay': [2447, 2905], 'buffer': [2448, 2454], 'solubilization': [2451], 'sample': [2453], 'SDS-polyacrylamide': [2456], 'gel': [2457], 'electrophoresis.': [2458], 'Detection': [2459], 'SDS-resistant': [2461], 'methods': [2468], '(8.Hayashi': [2469], 'Electrophoresed': [2493], 'samples': [2494], 'transferred': [2496], 'nitrocellulose': [2498], 'immunoblotting': [2500], 'antibodies:': [2504], 'polyclonal': [2506, 2520, 2537, 2562], 'rabbit': [2507, 2521, 2538, 2561], 'antibody': [2508, 2522, 2539, 2563, 2572, 2582], 'generated': [2509, 2523, 2540, 2564], 'C2AB': [2512], 'regions': [2513], 'III,': [2518], '15-residue': [2526], 'N-terminal': [2527], 'peptide': [2529, 2545], 'sequence': [2530], 'conjugated': [2531], '(residues': [2546], '195–206,': [2547], 'generously': [2548, 2587], 'obtained': [2554], 'commercially': [2555], 'StressGen': [2557], 'Biotechnologies': [2558], 'Corp.),': [2559], '(Alomone': [2567], 'Labs),': [2568], 'mouse': [2570, 2580, 2757], 'monoclonal': [2571, 2581, 2751], '(HPC-1,': [2576], 'Sigma),': [2577], '(Cl': [2585], '69.1,': [2586], 'Jahn).': [2591], '125I-Protein': [2592], 'goat': [2595], 'anti-mouse': [2596], 'IgG': [2597], '(NEN': [2598], 'Life': [2599], 'Science': [2600], 'Products)': [2601], 'secondary': [2605], 'reagents.': [2606], 'Autoradiograms': [2607], 'quantitated': [2609], 'Molecular': [2612], 'Dynamics': [2613], 'SI': [2614], 'Densitometer': [2615], 'ImageQuaNT': [2617], 'software.': [2618], 'native': [2622, 4117, 4289, 4312], 'assessed': [2628], 'brain': [2634, 2647, 4123, 4148, 4224], 'detergent': [2635, 2744, 4124, 4149, 4225], 'extracts': [2636, 2648, 2721, 2745, 4125, 4150, 4226], 'immobilized': [2640, 2759, 3388, 3459, 3760, 3971, 4231], 'above.': [2645], 'Rat': [2646], 'prepared': [2650], 'homogenizing': [2652], 'brains': [2654], '0.32': [2656], 'sucrose': [2658], '10': [2660], 'strokes': [2661], 'motor-driven': [2664], 'Teflon': [2665], 'glass': [2666], 'homogenizer.': [2667], 'Following': [2668], 'clarification': [2669], '5,000': [2671], 'rpm': [2672, 2688], 'SS34': [2678], 'rotor,': [2679], 'crude': [2680], 'synaptosomes': [2681], 'collected': [2683], '11,000': [2687], '12': [2690], 'solubilized': [2693], 'X-100': [2697], '0.1': [2704], 'mNaCl': [2705], 'inhibitors': [2708], '(1': [2709], 'phenylmethylsulfonyl': [2711], 'fluoride,': [2712], 'μg/ml': [2714, 2718], 'pepstatin,': [2715], '20': [2717], 'aprotinin).': [2719], 'Detergent': [2720], 'EGTA': [2727], 'mmCaCl2': [2730], 'immunoprecipitation': [2734, 4143], 'studies.': [2735], 'immunoprecipitations': [2737], 'antibodies': [2752], '(Sternberger': [2753], 'Monoclonals': [2754], 'Inc.)': [2755], 'immunoglobulins': [2758], 'A-Sepharose.': [2762], 'showed': [2774, 3487], 'Ca2+-triggered': [2780], 'fusion,': [2781], 'partially,': [2787], 'if': [2788], 'all,': [2790], 'effective': [2793, 2983, 4352], 'explanation': [2838], 'earlier': [2847], 'demonstrating': [2849], 'unique': [2857, 3069, 3157], 'being': [2859], 'synapses': [2866], 'We': [2887], 'therefore': [2888], 'examined': [2889], 'effects': [2891, 4322], 'cell-free': [2904], 'utilizes': [2907], 'strongly': [2940, 2969, 3144, 3468, 4089], 'all': [2946, 3038, 3150], 'tested': [2949, 3576], '(Fig.1,': [2950], 'upper': [2951, 3397, 3445, 4334], 'panel).': [2952, 3060, 3155, 3446, 3478], 'contrast,': [2954, 3780, 4033], 'intermediate': [2963], 'concentrations,': [2965], 'reduced': [2970, 4090, 4284], 'high': [2972, 4092], 'Ca2+concentrations.': [2973], 'maximally': [2982], 'catalyzed': [2986], 'similar': [2987, 3175, 3603, 3809, 4132, 4219], 'extents': [2988], '(∼80%,': [2992], 'shown).': [2994, 3590], 'Treatment': [2995], 'apparent': [3002], 'EC50': [3003, 3279, 4104], '(from': [3009], '2.3': [3010], '±': [3011, 3015, 3019], '0.3': [3012], '4.4': [3014], '1.1': [3016], 'μm;': [3017], 'mean': [3018], 'S.D.': [3020], 'six': [3022], 'experiments).': [3023], 'increase': [3025], 'simply': [3028], 'partial': [3033, 3823], 'attenuation': [3034], 'Ca2+concentrations': [3039, 4353], 'since': [3040], 'decreased': [3047], 'increasing': [3049], 'unlike': [3052], 'other': [3055], '(Fig.': [3057, 3153, 3394, 3442, 3474, 3500, 3535, 4058, 4095, 4139, 4233, 4261, 4294, 4332, 4346], '1,': [3058, 4333], 'middle': [3059], 'observed': [3076, 3166, 3568, 4071, 4135, 4251], '(39.Schiavo': [3083], 'Benfenati': [3085], 'Poulain': [3087], 'Rosetto': [3089], 'O.': [3090], 'Polverino': [3091], 'de': [3092], 'Laureto': [3093], '359:': [3101], '832-835Crossref': [3102], '(1459)': [3105], 'preferentially': [3113], '(40.Schiavo': [3116], 'Shone': [3118], 'C.C.': [3119], '10566-10570Abstract': [3131], '(241)': [3139], '1,lower': [3154], 'reported': [3178, 3402, 3598, 4008], 'more': [3184], 'systems': [3186], 'such': [3187], 'neuromuscular': [3190], 'junction': [3191], 'hippocampal': [3193], 'chromaffin': [3195], '41.Sellin': [3217], 'L.C.': [3218], 'Acta': [3223], 'Scand.': [3225], '1983;': [3226], '119:': [3227], '127-133Crossref': [3228], '(66)': [3231], '42.Capogna': [3234], 'McKinney': [3236], 'R.A.': [3237], "O'Connor": [3238], 'V.O.': [3239], 'Gahwiler': [3240], 'B.H.': [3241], 'Thompson': [3242], 'S.M.': [3243], '17:': [3247, 3706], '7190-7202Crossref': [3248], '43.Xu': [3252], 'Neher': [3258], '1:': [3263], '192-200Crossref': [3264], '(291)': [3267], 'Ca2+activation': [3281], 'we': [3284, 3368], 'considered': [3285], 'possibility': [3287], 'involved': [3291], 'has': [3303, 3913], 'been': [3304, 3915, 4364], 'function': [3307], 'Scholar,18.Geppert': [3324], 'so': [3367], 'determined': [3369], 'whether': [3370], 'interacts': [3372], 'directly': [3373], 'SNAP25.': [3375, 4113, 4315], 'absence': [3378, 3510, 3547, 3774, 3999], 'Ca2+,': [3380], 'recombinant': [3381, 3389, 3732, 4137, 4259], 'cytoplasmic': [3392, 3456, 3737, 3801], 'panel)': [3398, 4335], '(44.Schiavo': [3403, 4009], 'Stenbeck': [3405, 4011], '94:': [3419, 4025], '997-1001Crossref': [3420, 4026], '(259)': [3423, 4029], 'However,': [3426], 'inclusion': [3428, 3471, 4167], 'markedly': [3435, 4164, 4283, 4307], 'enhanced': [3436, 4165], 'reverse': [3449], 'orientation,': [3450], 'observed,': [3463], 'stimulated': [3469, 3490], 'lower': [3477], 'Quantitation': [3479], 'several': [3481], 'experiments': [3483], 'both': [3485], 'formats': [3486], 'interaction': [3492, 3527, 3588, 3729, 4036], '2.5–5-fold': [3499], 'B).': [3502, 3778, 4235], 'Ca2+was': [3512], 'relatively': [3514], 'low': [3515], 'affinity': [3516, 3524], '(K': [3517], 'D∼1.2': [3518], 'μm),': [3519], 'about': [3528], '6-fold': [3529], 'K': [3532], 'D∼0.2': [3533], 'C).': [3537], 'stoichiometry': [3539], 'saturation': [3544], 'presence': [3549, 3772], 'Ca2+approached': [3551], '1:1.': [3552], 'High': [3553], 'stimulate': [3559, 3586], 'half-maximal': [3566], 'stimulation': [3567, 4107], '∼200': [3570], '(Fig.3': [3573, 3777, 4002], 'A).': [3574, 4097, 4270], 'When': [3575], 'mm,': [3579], 'Sr2+,': [3580], 'Ba2+,': [3581], 'Mg2+': [3583], 'did': [3584, 3792], '(not': [3589], 'exhibit': [3600], 'very': [3602], 'dependence': [3605], 'cation': [3607], 'specificity': [3608], 'two': [3690], 'C2': [3691], 'domains': [3692], 'activities': [3696], '(45.Sudhof': [3700], 'Rizo': [3702], '379-388Abstract': [3707], '(397)': [3715], 'To': [3718, 3960], 'define': [3719, 3961], 'region': [3721, 3742, 3751, 3926, 3963], 'representing': [3734], 'full': [3736, 3796], '(C2AB),': [3739], 'membrane-proximal': [3741], 'C2A': [3745, 3782, 3820, 3921], '(C2A),': [3747], 'membrane-distal': [3750], 'C2B': [3754, 3763, 3932], '(C2B)': [3756], 'ligands.': [3761], 'exhibited': [3765, 3785, 3822, 4227], 'virtually': [3766], 'no': [3767], 'although': [3790], 'possess': [3794], 'activity': [3797, 3826], 'complete': [3800], 'where': [3818], 'recently': [3914], 'shown': [3916], 'linker': [3925], 'portion': [3929], '(62.Davis': [3934], 'A.F.': [3935], 'Bai': [3936], 'Wolowick': [3940], 'M.J.': [3941], 'Lewis': [3942], 'J.L.': [3943], '24:': [3948], '363-376Abstract': [3949], '(215)': [3957], 'binding,': [3970], 'quantitatively': [3974], 'truncated': [3983], 'retained': [3989], 'capacity': [3991], 'interact': [3993], 'C,': [4003, 4060], 'closed': [4004], 'bars)': [4005], 'open': [4061], 'bars).': [4062], 'extent': [4064], 'A-treated': [4074], 'dependent': [4077], 'upon': [4078], 'Additional': [4114], '4).': [4140, 4193], 'specific': [4142], 'resulted': [4151], 'co-isolation': [4154], '(Fig.4': [4158], 'lane': [4160, 4297], '2),': [4161], '(lane': [4170, 4192], 'versus': [4172, 4299], '2).': [4173], 'retention': [4176, 4210, 4229], 'immunoprecipitates': [4183], 'largely': [4185], 'eliminated': [4186], 'Neither': [4194, 4302], 'condition': [4195, 4207], 'altered': [4196], 'recovery': [4198], 'immunoprecipitates,': [4204], 'neither': [4206], 'promoted': [4208, 4237], 'CAPS,': [4212], 'abundant': [4214], 'cytosolic': [4215], 'protein.': [4216], 'manner,': [4220], 'over': [4241], 'same': [4243], 'range': [4245], '(EC50': [4246], '∼300': [4247], 'μm)': [4248], 'lanes': [4264], '3–6;': [4265], 'compare': [4266], 'Fig.': [4268], 'Cleavage': [4271], '6': [4298], '7and': [4300], '8).': [4301], 'nor': [4304], 'affected': [4308], 'There': [4316], 'considerable': [4318], 'similarities': [4319], 'reversing': [4326, 4338], 'I-SNAP25': [4344], 'A)': [4348], 'except': [4349], 'differed.': [4354], 'Several': [4355], 'isoforms': [4357], 'differ': [4359], 'sensitivity': [4362], 'characterized': [4365], '(26.Li': [4366], '24898-2490': [4398]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2020593055', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-14T02:52:38.729934', 'created_date': '2016-06-24'}