Clinical and Pathologic Impact of Select Chromatin-modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma

Name: Work Video:
Duration: 3 min 30 s
A. Ari Hakimi; Ying‐Bei Chen; James Wren; Mithat Gönen; Omar Abdel‐Wahab; Adriana Heguy; Han Liu; Shugaku Takeda; Satish K. Tickoo; Victor E. Reuter; Martin H. Voss; Robert J. Motzer; Jonathan Coleman; Emily H. Cheng; Paul Russo; James J. Hsieh
{'id': 'https://openalex.org/W2019756490', 'doi': 'https://doi.org/10.1016/j.eururo.2012.09.005', 'title': 'Clinical and Pathologic Impact of Select Chromatin-modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma', 'display_name': 'Clinical and Pathologic Impact of Select Chromatin-modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma', 'publication_year': 2012, 'publication_date': '2012-09-27', 'ids': {'openalex': 'https://openalex.org/W2019756490', 'doi': 'https://doi.org/10.1016/j.eururo.2012.09.005', 'mag': '2019756490', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23036577', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3615105'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.eururo.2012.09.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96871409', 'display_name': 'European Urology', 'issn_l': '0302-2838', 'issn': ['0302-2838', '1421-993X', '1873-7560'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc3615105?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5089094298', 'display_name': 'A. Ari Hakimi', 'orcid': 'https://orcid.org/0000-0002-0930-8824'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'A. Ari Hakimi', 'raw_affiliation_strings': ['Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003119579', 'display_name': 'Ying‐Bei Chen', 'orcid': 'https://orcid.org/0000-0001-5207-3648'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ying Bei Chen', 'raw_affiliation_strings': ['Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086226688', 'display_name': 'James Wren', 'orcid': 'https://orcid.org/0000-0002-2028-1132'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James Michael Wren', 'raw_affiliation_strings': ['Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051277222', 'display_name': 'Mithat Gönen', 'orcid': 'https://orcid.org/0000-0001-8683-8477'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mithat Gonen', 'raw_affiliation_strings': ['Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA,'], 'affiliations': [{'raw_affiliation_string': 'Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA,', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025595346', 'display_name': 'Omar Abdel‐Wahab', 'orcid': 'https://orcid.org/0000-0002-3907-6171'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Omar Abdel-Wahab', 'raw_affiliation_strings': ['Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center New York NY USA'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center New York NY USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025018584', 'display_name': 'Adriana Heguy', 'orcid': 'https://orcid.org/0000-0002-2836-6683'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Adriana Heguy', 'raw_affiliation_strings': ['Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100349032', 'display_name': 'Han Liu', 'orcid': 'https://orcid.org/0000-0002-0014-4675'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Han Liu', 'raw_affiliation_strings': ['Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060705907', 'display_name': 'Shugaku Takeda', 'orcid': 'https://orcid.org/0000-0003-4730-9390'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Shugaku Takeda', 'raw_affiliation_strings': ['Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028587910', 'display_name': 'Satish K. Tickoo', 'orcid': 'https://orcid.org/0000-0002-9775-0478'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Satish K. Tickoo', 'raw_affiliation_strings': ['Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010536553', 'display_name': 'Victor E. Reuter', 'orcid': 'https://orcid.org/0000-0002-7593-1016'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Victor E. Reuter', 'raw_affiliation_strings': ['Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091859782', 'display_name': 'Martin H. Voss', 'orcid': 'https://orcid.org/0000-0003-0551-5807'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Martin H. Voss', 'raw_affiliation_strings': ['Department of Medicine, Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059063118', 'display_name': 'Robert J. Motzer', 'orcid': 'https://orcid.org/0000-0001-6925-2327'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert J. Motzer', 'raw_affiliation_strings': ['Department of Medicine, Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081581200', 'display_name': 'Jonathan Coleman', 'orcid': 'https://orcid.org/0000-0002-6428-7835'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jonathan A. Coleman', 'raw_affiliation_strings': ['Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103090213', 'display_name': 'Emily H. Cheng', 'orcid': 'https://orcid.org/0000-0002-3595-2648'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Emily H. Cheng', 'raw_affiliation_strings': ['Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030709443', 'display_name': 'Paul Russo', 'orcid': 'https://orcid.org/0000-0001-7487-6783'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Paul Russo', 'raw_affiliation_strings': ['Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA'], 'affiliations': [{'raw_affiliation_string': 'Urology Service Department of Surgery Memorial Sloan-Kettering Cancer Center New York NY USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5021734597', 'display_name': 'James J. Hsieh', 'orcid': 'https://orcid.org/0000-0003-3595-0551'}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}, {'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James J. Hsieh', 'raw_affiliation_strings': ['Department of Medicine, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA', 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA', 'institution_ids': ['https://openalex.org/I205783295']}, {'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 5250, 'currency': 'USD', 'value_usd': 5250, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 8.925, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 223, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '63', 'issue': '5', 'first_page': '848', 'last_page': '854'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10449', 'display_name': 'Renal cell carcinoma treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bap1', 'display_name': 'BAP1', 'score': 0.9607322}, {'id': 'https://openalex.org/keywords/clinical-significance', 'display_name': 'Clinical Significance', 'score': 0.43868586}], 'concepts': [{'id': 'https://openalex.org/C37846818', 'wikidata': 'https://www.wikidata.org/wiki/Q18032813', 'display_name': 'BAP1', 'level': 3, 'score': 0.9607322}, {'id': 'https://openalex.org/C2781278892', 'wikidata': 'https://www.wikidata.org/wiki/Q18556340', 'display_name': 'Clear cell renal cell carcinoma', 'level': 3, 'score': 0.81643414}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6423665}, {'id': 'https://openalex.org/C2777472916', 'wikidata': 'https://www.wikidata.org/wiki/Q1164529', 'display_name': 'Renal cell carcinoma', 'level': 2, 'score': 0.4963644}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.48482955}, {'id': 'https://openalex.org/C2778560582', 'wikidata': 'https://www.wikidata.org/wiki/Q18347894', 'display_name': 'Clear cell', 'level': 3, 'score': 0.45143774}, {'id': 'https://openalex.org/C63363279', 'wikidata': 'https://www.wikidata.org/wiki/Q5133848', 'display_name': 'Clinical significance', 'level': 2, 'score': 0.43868586}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.39343715}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34637308}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.34293783}], 'mesh': [{'descriptor_ui': 'D002292', 'descriptor_name': 'Carcinoma, Renal Cell', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D002292', 'descriptor_name': 'Carcinoma, Renal Cell', 'qualifier_ui': 'Q000556', 'qualifier_name': 'secondary', 'is_major_topic': True}, {'descriptor_ui': 'D042002', 'descriptor_name': 'Chromatin Assembly and Disassembly', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016147', 'descriptor_name': 'Genes, Tumor Suppressor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007680', 'descriptor_name': 'Kidney Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D007680', 'descriptor_name': 'Kidney Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002292', 'descriptor_name': 'Carcinoma, Renal Cell', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D002292', 'descriptor_name': 'Carcinoma, Renal Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D042002', 'descriptor_name': 'Chromatin Assembly and Disassembly', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004252', 'descriptor_name': 'DNA Mutational Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005787', 'descriptor_name': 'Gene Frequency', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020022', 'descriptor_name': 'Genetic Predisposition to Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053208', 'descriptor_name': 'Kaplan-Meier Estimate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007680', 'descriptor_name': 'Kidney Neoplasms', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D007680', 'descriptor_name': 'Kidney Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060787', 'descriptor_name': 'Neoplasm Grading', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009367', 'descriptor_name': 'Neoplasm Staging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016017', 'descriptor_name': 'Odds Ratio', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047368', 'descriptor_name': 'Tumor Burden', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.eururo.2012.09.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96871409', 'display_name': 'European Urology', 'issn_l': '0302-2838', 'issn': ['0302-2838', '1421-993X', '1873-7560'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3615105', 'pdf_url': 'https://europepmc.org/articles/pmc3615105?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615105', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23036577', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3615105', 'pdf_url': 'https://europepmc.org/articles/pmc3615105?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.78}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W1511815964', 'https://openalex.org/W1520588455', 'https://openalex.org/W1571627051', 'https://openalex.org/W1977845140', 'https://openalex.org/W1995684639', 'https://openalex.org/W1999491723', 'https://openalex.org/W2007265317', 'https://openalex.org/W2008285831', 'https://openalex.org/W2008809596', 'https://openalex.org/W2015416439', 'https://openalex.org/W2016444631', 'https://openalex.org/W2024064023', 'https://openalex.org/W2057802075', 'https://openalex.org/W2060605982', 'https://openalex.org/W2072257321', 'https://openalex.org/W2079212177', 'https://openalex.org/W2085531754', 'https://openalex.org/W2092892924', 'https://openalex.org/W2095698093', 'https://openalex.org/W2102057116', 'https://openalex.org/W2103313018', 'https://openalex.org/W2106417221', 'https://openalex.org/W2106797333', 'https://openalex.org/W2111326065', 'https://openalex.org/W2115494288', 'https://openalex.org/W2126675803', 'https://openalex.org/W2150575159', 'https://openalex.org/W2161609794', 'https://openalex.org/W2331498988', 'https://openalex.org/W4238906713'], 'related_works': ['https://openalex.org/W4388312533', 'https://openalex.org/W4376526696', 'https://openalex.org/W4289731958', 'https://openalex.org/W3098705614', 'https://openalex.org/W2907865819', 'https://openalex.org/W2898452673', 'https://openalex.org/W2890931368', 'https://openalex.org/W2019756490', 'https://openalex.org/W2004612544', 'https://openalex.org/W1994819973'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2019756490', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 10}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 31}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 20}, {'year': 2017, 'cited_by_count': 21}, {'year': 2016, 'cited_by_count': 29}, {'year': 2015, 'cited_by_count': 22}, {'year': 2014, 'cited_by_count': 25}, {'year': 2013, 'cited_by_count': 22}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-08T17:00:57.700553', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
