Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2019687915', 'doi': 'https://doi.org/10.1016/0968-0004(94)90133-3', 'title': 'The ins and outs of Raf kinases', 'display_name': 'The ins and outs of Raf kinases', 'publication_year': 1994, 'publication_date': '1994-11-01', 'ids': {'openalex': 'https://openalex.org/W2019687915', 'doi': 'https://doi.org/10.1016/0968-0004(94)90133-3', 'mag': '2019687915', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7855890'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0968-0004(94)90133-3', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136233269', 'display_name': 'Trends in Biochemical Sciences', 'issn_l': '0968-0004', 'issn': ['0968-0004', '1362-4326'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108410466', 'display_name': 'Günter Daum', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I25974101', 'display_name': 'University of Würzburg', 'ror': 'https://ror.org/00fbnyb24', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I25974101']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Günter Daum', 'raw_affiliation_strings': ['G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany', 'institution_ids': ['https://openalex.org/I25974101']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075930077', 'display_name': 'Iris Eisenmann-Tappe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I25974101', 'display_name': 'University of Würzburg', 'ror': 'https://ror.org/00fbnyb24', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I25974101']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Iris Eisenmann-Tappe', 'raw_affiliation_strings': ['G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany', 'institution_ids': ['https://openalex.org/I25974101']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012087549', 'display_name': 'Hans-Werner Fries', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I25974101', 'display_name': 'University of Würzburg', 'ror': 'https://ror.org/00fbnyb24', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I25974101']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Hans-Werner Fries', 'raw_affiliation_strings': ['G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany', 'institution_ids': ['https://openalex.org/I25974101']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008315598', 'display_name': 'Jakob Troppmair', 'orcid': 'https://orcid.org/0000-0002-0611-3837'}, 'institutions': [{'id': 'https://openalex.org/I25974101', 'display_name': 'University of Würzburg', 'ror': 'https://ror.org/00fbnyb24', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I25974101']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Jakob Troppmair', 'raw_affiliation_strings': ['G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany', 'institution_ids': ['https://openalex.org/I25974101']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5001270756', 'display_name': 'Ulf R. Rapp', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I25974101', 'display_name': 'University of Würzburg', 'ror': 'https://ror.org/00fbnyb24', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I25974101']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Ulf R. Rapp', 'raw_affiliation_strings': ['G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'G. Daum, I. Eisenmann-Tappe, H-W. Fries, J. Troppmair and U.R. Rapp are at the Institute of Medical Radiobiology and Cell Biology, University of Würzburg, Versbacher Strasse 5, D-97078 Würzburg, Germany', 'institution_ids': ['https://openalex.org/I25974101']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 6830, 'currency': 'USD', 'value_usd': 6830, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 7.378, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 537, 'citation_normalized_percentile': {'value': 0.930163, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '19', 'issue': '11', 'first_page': '474', 'last_page': '480'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11533', 'display_name': 'Melanoma and MAPK Pathways', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11533', 'display_name': 'Melanoma and MAPK Pathways', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12835', 'display_name': 'FOXO transcription factor regulation', 'score': 0.9929, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11503', 'display_name': 'Cytokine Signaling Pathways and Interactions', 'score': 0.9895, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C184235292', 'wikidata': 'https://www.wikidata.org/wiki/Q421851', 'display_name': 'Kinase', 'level': 2, 'score': 0.70232576}, {'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.657008}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5998089}, {'id': 'https://openalex.org/C2910050888', 'wikidata': 'https://www.wikidata.org/wiki/Q4857068', 'display_name': 'Protein-Serine-Threonine Kinases', 'level': 4, 'score': 0.5938897}, {'id': 'https://openalex.org/C101544691', 'wikidata': 'https://www.wikidata.org/wiki/Q420511', 'display_name': 'Receptor tyrosine kinase', 'level': 3, 'score': 0.5614466}, {'id': 'https://openalex.org/C2775880066', 'wikidata': 'https://www.wikidata.org/wiki/Q186521', 'display_name': 'Threonine', 'level': 4, 'score': 0.5349404}, {'id': 'https://openalex.org/C2776414213', 'wikidata': 'https://www.wikidata.org/wiki/Q183290', 'display_name': 'Serine', 'level': 3, 'score': 0.5269614}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.45334268}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4298664}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3281576}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3106952}, {'id': 'https://openalex.org/C97029542', 'wikidata': 'https://www.wikidata.org/wiki/Q281417', 'display_name': 'Protein kinase A', 'level': 3, 'score': 0.282969}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.06716514}], 'mesh': [{'descriptor_ui': 'D017346', 'descriptor_name': 'Protein Serine-Threonine Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017346', 'descriptor_name': 'Protein Serine-Threonine Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019908', 'descriptor_name': 'Proto-Oncogene Proteins c-raf', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0968-0004(94)90133-3', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136233269', 'display_name': 'Trends in Biochemical Sciences', 'issn_l': '0968-0004', 'issn': ['0968-0004', '1362-4326'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7855890', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Life on land', 'id': 'https://metadata.un.org/sdg/15', 'score': 0.46}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W145366285', 'https://openalex.org/W1487879160', 'https://openalex.org/W1518252063', 'https://openalex.org/W1539582413', 'https://openalex.org/W1540963075', 'https://openalex.org/W1577992990', 'https://openalex.org/W1585517331', 'https://openalex.org/W1675086682', 'https://openalex.org/W1962420186', 'https://openalex.org/W1968401207', 'https://openalex.org/W1969785844', 'https://openalex.org/W1971180899', 'https://openalex.org/W1971977518', 'https://openalex.org/W1972008234', 'https://openalex.org/W1974564127', 'https://openalex.org/W1994926193', 'https://openalex.org/W2002292023', 'https://openalex.org/W2004629227', 'https://openalex.org/W2026951979', 'https://openalex.org/W2029275361', 'https://openalex.org/W2029869462', 'https://openalex.org/W2046216255', 'https://openalex.org/W2061920396', 'https://openalex.org/W2088854448', 'https://openalex.org/W2143678301', 'https://openalex.org/W2171569176', 'https://openalex.org/W2171596565', 'https://openalex.org/W2432579033', 'https://openalex.org/W2473183335', 'https://openalex.org/W346745165', 'https://openalex.org/W4249015842'], 'related_works': ['https://openalex.org/W4255835953', 'https://openalex.org/W4251675583', 'https://openalex.org/W4239074997', 'https://openalex.org/W4232519528', 'https://openalex.org/W2912581221', 'https://openalex.org/W2300735653', 'https://openalex.org/W2125033869', 'https://openalex.org/W2116966920', 'https://openalex.org/W1978122481', 'https://openalex.org/W1557644410'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2019687915', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-16T11:35:07.516359', 'created_date': '2016-06-24'}