Title: A Ratiometric and Targetable Fluorescent Sensor for Quantification of Mitochondrial Zinc Ions
Abstract: Chemistry – A European JournalVolume 18, Issue 4 p. 1050-1054 Communication A Ratiometric and Targetable Fluorescent Sensor for Quantification of Mitochondrial Zinc Ions Lin Xue, Lin Xue Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this authorGuoping Li, Guoping Li Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this authorCailan Yu, Cailan Yu Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this authorProf. Hua Jiang, Corresponding Author Prof. Hua Jiang [email protected] Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this author Lin Xue, Lin Xue Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this authorGuoping Li, Guoping Li Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this authorCailan Yu, Cailan Yu Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this authorProf. Hua Jiang, Corresponding Author Prof. Hua Jiang [email protected] Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, 100190 (P.R. China)Search for more papers by this author First published: 21 December 2011 https://doi.org/10.1002/chem.201103007Citations: 72Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract Trapping in mitochondria: A ratiometric fluorescent sensor for the detection of mitochondrial Zn2+ was synthesised and evaluated on the basis of inhibition of resonance. The sensor, with good selectivity and high sensitivity, can quantify the free Zn2+ level in mitochondria, and can be used to visualise the mitochondrial Zn2+ change in living cells (see figure). Supporting Information Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description chem_201103007_sm_miscellaneous_information.pdf3.9 MB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. References 1 1aD. W. Domaille, E. L. Que, C. J. Chang, Nat. Chem. Biol. 2008, 4, 168–175; 1bT. Terai, T. Nagano, Curr. Opin. Chem. Biol. 2008, 12, 515–521. 2 2aX. Xie, T. G. Smart, Nature 1991, 349, 521–524; 2bJ. M. Berg, Y. 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Publication Year: 2011
Publication Date: 2011-12-21
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 79
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