Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2018847636', 'doi': 'https://doi.org/10.1021/ja038381e', 'title': 'Paranemic Crossover DNA: A Generalized Holliday Structure with Applications in Nanotechnology', 'display_name': 'Paranemic Crossover DNA: A Generalized Holliday Structure with Applications in Nanotechnology', 'publication_year': 2004, 'publication_date': '2004-01-23', 'ids': {'openalex': 'https://openalex.org/W2018847636', 'doi': 'https://doi.org/10.1021/ja038381e', 'mag': '2018847636', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/14871096', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3737428'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ja038381e', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111155417', 'display_name': 'Journal of the American Chemical Society', 'issn_l': '0002-7863', 'issn': ['0002-7863', '1520-5126', '1943-2984'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc3737428?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5000199801', 'display_name': 'Zhiyong Shen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Zhiyong Shen', 'raw_affiliation_strings': ['Contribution from the Department of Chemistry, New York University, New York, New York 10003'], 'affiliations': [{'raw_affiliation_string': 'Contribution from the Department of Chemistry, New York University, New York, New York 10003', 'institution_ids': ['https://openalex.org/I57206974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064979753', 'display_name': 'Hao Yan', 'orcid': 'https://orcid.org/0000-0001-7397-9852'}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hao Yan', 'raw_affiliation_strings': ['Contribution from the Department of Chemistry, New York University, New York, New York 10003'], 'affiliations': [{'raw_affiliation_string': 'Contribution from the Department of Chemistry, New York University, New York, New York 10003', 'institution_ids': ['https://openalex.org/I57206974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100450964', 'display_name': 'Tong Wang', 'orcid': 'https://orcid.org/0000-0001-6615-000X'}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tong Wang', 'raw_affiliation_strings': ['Contribution from the Department of Chemistry, New York University, New York, New York 10003'], 'affiliations': [{'raw_affiliation_string': 'Contribution from the Department of Chemistry, New York University, New York, New York 10003', 'institution_ids': ['https://openalex.org/I57206974']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5003005300', 'display_name': 'Nadrian C. Seeman', 'orcid': 'https://orcid.org/0000-0002-9680-4649'}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nadrian C. Seeman', 'raw_affiliation_strings': ['Contribution from the Department of Chemistry, New York University, New York, New York 10003'], 'affiliations': [{'raw_affiliation_string': 'Contribution from the Department of Chemistry, New York University, New York, New York 10003', 'institution_ids': ['https://openalex.org/I57206974']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.396, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 180, 'citation_normalized_percentile': {'value': 0.999979, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '126', 'issue': '6', 'first_page': '1666', 'last_page': '1674'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10207', 'display_name': 'Advanced biosensing and bioanalysis techniques', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10207', 'display_name': 'Advanced biosensing and bioanalysis techniques', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10432', 'display_name': 'DNA and Nucleic Acid Chemistry', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C130965112', 'wikidata': 'https://www.wikidata.org/wiki/Q1624837', 'display_name': 'Holliday junction', 'level': 4, 'score': 0.90583855}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.89820856}, {'id': 'https://openalex.org/C171250308', 'wikidata': 'https://www.wikidata.org/wiki/Q11468', 'display_name': 'Nanotechnology', 'level': 1, 'score': 0.6340312}, {'id': 'https://openalex.org/C122507166', 'wikidata': 'https://www.wikidata.org/wiki/Q628906', 'display_name': 'Crossover', 'level': 2, 'score': 0.5375163}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.5162406}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C102744134', 'wikidata': 'https://www.wikidata.org/wiki/Q22280388', 'display_name': 'Homologous recombination', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C154945302', 'wikidata': 'https://www.wikidata.org/wiki/Q11660', 'display_name': 'Artificial intelligence', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D036103', 'descriptor_name': 'Nanotechnology', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D002942', 'descriptor_name': 'Circular Dichroism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000138', 'qualifier_name': 'chemical synthesis', 'is_major_topic': False}, {'descriptor_ui': 'D018983', 'descriptor_name': 'DNA Footprinting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004586', 'descriptor_name': 'Electrophoresis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054856', 'descriptor_name': 'G-Quadruplexes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006358', 'descriptor_name': 'Hot Temperature', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006860', 'descriptor_name': 'Hydrogen Bonding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017665', 'descriptor_name': 'Hydroxyl Radical', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D009690', 'descriptor_name': 'Nucleic Acid Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ja038381e', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111155417', 'display_name': 'Journal of the American Chemical Society', 'issn_l': '0002-7863', 'issn': ['0002-7863', '1520-5126', '1943-2984'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3737428', 'pdf_url': 'https://europepmc.org/articles/pmc3737428?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737428', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/14871096', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3737428', 'pdf_url': 'https://europepmc.org/articles/pmc3737428?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1507168345', 'https://openalex.org/W1567090568', 'https://openalex.org/W1567767550', 'https://openalex.org/W1588048883', 'https://openalex.org/W1617520624', 'https://openalex.org/W1656731888', 'https://openalex.org/W1877880288', 'https://openalex.org/W1964451198', 'https://openalex.org/W1972139613', 'https://openalex.org/W1974231617', 'https://openalex.org/W1978648636', 'https://openalex.org/W1980403812', 'https://openalex.org/W1986390091', 'https://openalex.org/W1986730363', 'https://openalex.org/W1988959992', 'https://openalex.org/W1993748356', 'https://openalex.org/W1998164097', 'https://openalex.org/W2006908644', 'https://openalex.org/W2008596281', 'https://openalex.org/W2009943333', 'https://openalex.org/W2011108001', 'https://openalex.org/W2015553561', 'https://openalex.org/W2017276607', 'https://openalex.org/W2021529955', 'https://openalex.org/W2023747155', 'https://openalex.org/W2028143623', 'https://openalex.org/W2028521594', 'https://openalex.org/W2030673893', 'https://openalex.org/W2035421467', 'https://openalex.org/W2037120730', 'https://openalex.org/W2038125628', 'https://openalex.org/W2046002563', 'https://openalex.org/W2048178077', 'https://openalex.org/W2051952928', 'https://openalex.org/W2057792991', 'https://openalex.org/W2068480338', 'https://openalex.org/W2068744615', 'https://openalex.org/W2069109754', 'https://openalex.org/W2080311192', 'https://openalex.org/W2082410415', 'https://openalex.org/W2098818518', 'https://openalex.org/W2106111891', 'https://openalex.org/W2113854943', 'https://openalex.org/W2123017921', 'https://openalex.org/W2126466006', 'https://openalex.org/W2134768908', 'https://openalex.org/W2142450735', 'https://openalex.org/W2172060739', 'https://openalex.org/W2313993185', 'https://openalex.org/W2335390566', 'https://openalex.org/W2616798345', 'https://openalex.org/W2995121509', 'https://openalex.org/W4253664160', 'https://openalex.org/W4256439663'], 'related_works': ['https://openalex.org/W4391375266', 'https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2166911703', 'https://openalex.org/W2078814861', 'https://openalex.org/W2072343802', 'https://openalex.org/W1531601525', 'https://openalex.org/W1197411634'], 'abstract_inverted_index': {'Paranemic': [0], 'crossover': [1, 55, 121, 188, 219], '(PX)': [2], 'DNA': [3, 8, 44, 102, 162, 186], 'is': [4, 38, 112, 173, 217], 'a': [5, 11, 80, 104, 120, 202, 218], 'four-stranded': [6], 'coaxial': [7], 'complex': [9], 'containing': [10], 'central': [12, 59], 'dyad': [13, 60], 'axis': [14, 61], 'that': [15, 39, 153, 170, 178, 215], 'relates': [16], 'two': [17, 41, 140], 'flanking': [18], 'parallel': [19, 43], 'double': [20, 45, 187], 'helices.': [21], 'The': [22, 32], 'strands': [23], 'are': [24, 156, 181, 193, 233], 'held': [25], 'together': [26], 'exclusively': [27], 'by': [28], 'Watson-Crick': [29], 'base': [30], 'pairing.': [31], 'key': [33], 'feature': [34], 'of': [35, 84, 92, 108, 135, 207, 223], 'the': [36, 40, 58, 132, 154, 171, 179, 208, 224, 228], 'structure': [37], 'adjacent': [42], 'helices': [46], 'form': [47], 'crossovers': [48], 'at': [49, 62, 114, 221], 'every': [50, 63, 122], 'point': [51, 220], 'possible.': [52], 'Hence,': [53], 'reciprocal': [54], 'points': [56], 'flank': [57], 'major': [64, 89, 105], 'or': [65, 95, 128, 146], 'minor': [66, 81], 'groove': [67, 82, 90, 106], 'separation.': [68], 'This': [69], 'motif': [70], 'has': [71], 'been': [72], 'modeled': [73], 'and': [74, 88], 'characterized': [75], 'in': [76, 183, 205, 227], 'an': [77], 'oligonucleotide': [78], 'system;': [79], 'separation': [83, 107], 'five': [85], 'nucleotide': [86, 97, 110], 'pairs': [87, 98, 111], 'separations': [91], 'six,': [93], 'seven,': [94], 'eight': [96], 'produce': [99], 'stable': [100], 'PX': [101, 161], 'molecules;': [103], '9': [109], 'possible': [113], 'low': [115], 'concentrations.': [116], 'Every': [117], 'strand': [118, 137], 'undergoes': [119], 'helical': [123, 141], 'repeat': [124], '(11,': [125], '12,': [126], '13,': [127], '14': [129], 'nucleotides),': [130], 'but': [131], 'structural': [133], 'period': [134], 'each': [136, 206, 222], 'corresponds': [138], 'to': [139, 185], 'repeats': [142], '(22,': [143], '24,': [144], '26,': [145], '28': [147], 'nucleotides).': [148], 'Nondenaturing': [149], 'gel': [150], 'electrophoresis': [151], 'shows': [152], 'molecules': [155, 180, 232], 'stable,': [157], 'forming': [158], 'well-behaved': [159], 'complexes.': [160], 'can': [163], 'be': [164], 'produced': [165], 'from': [166], 'closed': [167], 'dumbbells,': [168], 'demonstrating': [169], 'molecule': [172], 'paranemic.': [174], 'Ferguson': [175], 'analysis': [176, 213], 'indicates': [177], 'similar': [182], 'shape': [184], 'molecules.': [189, 209], 'Circular': [190], 'dichroism': [191], 'spectra': [192], 'consistent': [194], 'with': [195], 'B-form': [196], 'DNA.': [197], 'Thermal': [198], 'transition': [199, 204], 'profiles': [200], 'suggest': [201], 'premelting': [203], 'Hydroxyl': [210], 'radical': [211], 'autofootprinting': [212], 'confirms': [214], 'there': [216], 'positions': [225], 'expected': [226], 'secondary': [229], 'structure.': [230], 'These': [231], 'generalized': [234], 'Holliday': [235], 'junctions.': [236]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2018847636', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-13T13:30:56.101573', 'created_date': '2016-06-24'}