Publication Information

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158, 187, 215, 357, 386, 594, 637, 920, 927, 1095, 1212, 1220, 1270, 1544, 1612, 1619, 1660, 1721, 1816, 1947, 1994, 2059, 2097, 2173, 2365, 2421, 2531, 2583, 2757, 2908, 3088, 3096, 3165, 3264], 'ribonucleoprotein': [17, 216, 928, 1620], 'complex,': [18, 217], 'catalyzes': [19, 218], 'the': [20, 23, 30, 77, 110, 130, 137, 163, 179, 192, 219, 222, 229, 276, 309, 329, 336, 362, 378, 391, 400, 404, 412, 415, 425, 531, 544, 564, 572, 627, 650, 761, 767, 858, 1030, 1060, 1084, 1090, 1227, 1387, 1553, 1561, 1653, 1767, 1813, 1822, 1926, 2083, 2129, 2244, 2255, 2269, 2360, 2387, 2399, 2405, 2428, 2500, 2545, 2563, 2566, 2576, 2610, 2639, 2655, 2665, 2737, 2767, 2777, 2787, 2863, 2874, 2883, 2914, 3121, 3131, 3169, 3224, 3347, 3356, 3414, 3436], 'elongation': [21, 220], 'ends': [24, 223, 532], 'mammalian': [26, 225, 3135], 'chromosomal': [27, 226], 'DNA': [28, 227, 576, 582, 623, 933, 1899, 2047, 3272], '(telomeres),': [29, 228], 'length': [31, 230], 'which': [33, 232, 2331, 2497], 'regulates': [34, 178, 233, 377], 'proliferation.': [36, 235], 'Currently,': [37, 236], 'how': [38, 237], 'is': [40, 44, 55, 186, 239, 243, 254, 385, 411, 583, 926, 1017, 1238, 1253, 1434, 1541, 1608, 1618, 1678, 1704, 2441, 2550, 2559, 2598, 2606, 2697, 2714, 2841, 2850, 2870, 2891, 2897, 3118, 3125, 3263, 3389], 'regulated': [41, 56, 240, 255, 1542, 1610, 2232, 2852], 'not': [45, 135, 244, 334, 1263, 2215, 2591, 2670], 'yet': [46, 245, 1258, 2710], 'established.': [47, 246, 2217], 'The': [48, 247, 1665, 1700, 1762, 2207, 2218, 2433, 2518, 2593], 'present': [49, 248, 1666, 3126], 'study': [50, 249, 1667], 'shows': [51, 250, 1668], 'that': [52, 174, 184, 251, 373, 383, 578, 1265, 1377, 1600, 1655, 1669, 2475, 2544, 2565, 2595, 2693, 2704, 2749, 2803, 2848, 2872, 2894, 2911, 3116, 3392, 3413], 'by': [57, 99, 109, 121, 125, 153, 256, 298, 308, 320, 324, 352, 420, 1255, 1436, 1611, 1681, 1708, 1713, 1727, 1805, 1830, 1946, 2058, 2094, 2103, 2115, 2233, 2350, 2420, 2431, 2439, 2459, 2523, 2527, 2562, 2609, 2651, 2660, 2674, 2707, 2722, 2736, 2812, 2853, 3217, 3396], 'protein': [58, 72, 88, 111, 127, 175, 257, 271, 287, 310, 326, 374, 772, 862, 892, 1021, 1626, 1656, 1682, 1691, 1714, 1718, 1728, 1906, 1983, 2234, 2248, 2293, 2445, 2467, 2482, 2596, 2613, 2622, 2640, 2645, 2705, 2712, 2730, 2738, 2750, 2854, 2860, 2864, 2885, 2895, 3350], 'phosphorylation': [59, 176, 258, 375, 1631, 1657, 1715, 1729, 2614, 2623, 2646, 2706, 2751, 2855, 2896, 3212], 'human': [61, 146, 195, 260, 345, 394, 409, 645, 859, 1249, 1383, 1429, 1537, 2176, 2261, 2770, 2788], 'breast': [62, 147, 196, 261, 346, 395, 1538, 1674, 1733, 2262, 2771, 2789, 3437], 'cells.': [64, 170, 198, 263, 369, 397, 1245, 2265, 2408, 2773], 'Incubation': [65, 264], 'nuclear': [68, 118, 267, 317, 1670, 1930, 2324, 2370, 2436, 2484, 2625], 'extracts': [70, 269, 1984, 2145, 2325, 2486, 2627], 'with': [71, 157, 270, 356, 1226, 1231, 1548, 1622, 1773, 1815, 1844, 1937, 2131, 2146, 2172, 2291, 2386, 2396, 2489, 2534, 2582, 2631, 2793, 2844], 'phosphatase': [73, 112, 272, 311, 1683, 1692, 2446, 2641, 2865], '2A': [74, 273, 1684], '(PP2A)': [75, 274], 'abolished': [76, 275, 1680], 'activity;': [79, 278], 'contrast': [81, 280], 'cytoplasmic': [82, 281, 2279], 'was': [85, 101, 107, 123, 151, 284, 300, 306, 322, 350, 1856, 1912, 1942, 2041, 2087, 2113, 2160, 2224, 2272, 2283, 2332, 2525, 2573, 2578, 2647, 2676, 2734, 2809, 2825], 'unaffected,': [86, 285], 'and': [87, 91, 104, 106, 183, 286, 290, 303, 305, 382, 547, 560, 569, 789, 840, 890, 1026, 1052, 1056, 1424, 1556, 1606, 1711, 1730, 1784, 1795, 1821, 1824, 1890, 1902, 1918, 1929, 2049, 2074, 2126, 2252, 2278, 2297, 2341, 2371, 2390, 2491, 2615, 2703, 2752, 2762, 2801, 2830, 2856, 2862, 2893, 3093, 3095, 3158, 3219, 3329, 3360, 3412, 3449, 3455], 'phosphatases': [89, 288, 2249, 2294], '1': [90, 289, 1980, 2022, 2031, 2327, 2339, 2377, 2402, 2447], '2B': [92, 291, 2298, 2449], 'were': [93, 292, 1764, 1803, 1827, 1842, 1892, 1907, 1920, 1985, 2384, 2487, 2628], 'ineffective.': [94, 293], 'Inhibition': [95, 294, 2455], 'PP2A': [100, 122, 161, 185, 299, 321, 360, 384, 1703, 1853, 2318, 2355, 2440, 2460, 2490, 2504, 2524, 2549, 2569, 2577, 2587, 2601, 2632, 2675, 2686, 3094, 3100, 3117, 3124, 3214, 3227, 3262, 3354, 3359, 3395, 3418], 'both': [102, 301], 'concentration-': [103, 302], 'time-dependent': [105, 304], 'prevented': [108, 307, 2526], 'inhibitor': [113, 312, 2642, 2740], 'okadaic': [114, 154, 313, 353, 1709, 1845, 2495, 2528, 2794, 2813], 'acid.': [115, 314], 'In': [116, 315, 1246, 1532, 1835, 2620, 2664, 2724, 2867], 'addition,': [117, 316, 1533, 2868, 3344], 'inhibited': [120, 319, 2320, 2356, 2673, 2735], 'reactivated': [124, 323, 2677], 'endogenous': [126, 325, 1717], 'kinase(s)': [128, 327, 2713, 2861], 'presence': [131, 138, 330, 337, 2656, 2666], 'ATP,': [133, 332, 2658, 2668], 'but': [134, 333, 1274, 2669], 'ATPγS.': [140, 339], 'Furthermore,': [141, 340, 3084], 'cultured': [145, 344, 2270, 2406], 'PMC42': [149, 348, 1676, 1735, 2264, 2407, 2791], 'stimulated': [152, 351, 2811], 'acid,': [155, 354, 2496], 'consistent': [156, 355, 2843], 'role': [159, 358, 596, 1661, 3167], 'for': [160, 359, 597, 931, 1272, 1277, 1990, 2066, 2071, 2077, 2090, 2106, 2157, 2274, 2552, 2633, 2796, 2899, 3434, 3452, 3458], 'regulation': [164, 363, 762, 1723, 2210, 2916], 'intact': [169, 368, 2783], 'These': [171, 370, 551, 1597, 2745], 'findings': [172, 371, 1598, 2847, 3086], 'suggest': [173, 372, 1599, 2748, 3087, 3115], 'reversibly': [177, 376, 1609, 2851], 'function': [180, 379, 554, 638], 'inhibitory': [189, 388, 2429], 'factor': [190, 389], 'nucleus': [193, 392, 2388, 2768, 3132], 'One': [398, 423], 'critical': [401], 'events': [402], 'oncogenic': [405, 3122, 3349, 3397], 'progression': [406], 'normal': [408, 432, 644, 1233, 1243, 1382], 'escape': [413], 'from': [414, 1849, 1858, 1868, 1893, 1908, 1913, 1921, 1934, 2128, 2260, 3112], 'limitations': [416], 'on': [417, 2096, 2121, 2254, 2570, 2838], 'proliferation': [418, 1283, 3363], 'imposed': [419], 'cellular': [421, 429, 1437, 2247], 'senescence.': [422], 'primary': [426, 921, 1248, 2219], 'mechanisms': [427, 651, 2208], 'underlying': [428, 652], 'senescence': [430, 654], 'diploid': [433], 'involves': [435, 2481], 'controlled': [436], 'telomere': [437, 587, 764, 924, 932, 2903], 'shortening': [438, 1228], 'division': [441, 642, 1280, 2922], '(for': [442], 'reviews,': [443], 'see': [444], 'Refs.': [445], '1Blackburn': [446], 'E.H.': [447, 611, 936, 1123], 'Annu.': [448, 516, 937, 1005, 2507], 'Rev.': [449, 517, 938, 1006, 2508], 'Biochem.': [450, 518, 939, 1007, 1520, 2509, 3039], '1992;': [451, 671, 692, 940, 3235], '61:': [452, 941], '113-129Crossref': [453, 942], 'PubMed': [454, 472, 522, 616, 674, 695, 724, 749, 784, 817, 835, 853, 884, 914, 943, 961, 1011, 1047, 1078, 1115, 1131, 1145, 1186, 1204, 1303, 1369, 1400, 1419, 1527, 1592, 1646, 1884, 2202, 2312, 2513, 2934, 2953, 3046, 3079, 3153, 3188, 3206, 3238, 3258, 3302, 3324, 3340, 3383], 'Scopus': [455, 473, 510, 523, 617, 675, 696, 725, 750, 785, 818, 836, 854, 885, 915, 944, 962, 999, 1012, 1048, 1079, 1116, 1132, 1146, 1187, 1205, 1304, 1341, 1370, 1401, 1420, 1469, 1528, 1593, 1647, 1885, 1975, 2203, 2313, 2514, 2935, 2954, 2988, 3047, 3080, 3154, 3189, 3207, 3239, 3303, 3325, 3384], '(593)': [456, 945], 'Google': [457, 475, 512, 525, 619, 677, 698, 727, 752, 787, 820, 838, 856, 887, 917, 946, 964, 1001, 1014, 1050, 1081, 1118, 1134, 1148, 1189, 1207, 1306, 1343, 1372, 1403, 1422, 1471, 1488, 1502, 1530, 1595, 1649, 1760, 1887, 1977, 2205, 2315, 2516, 2937, 2956, 2990, 3007, 3021, 3049, 3082, 3156, 3191, 3209, 3241, 3259, 3305, 3327, 3341, 3386], 'Scholar,': [458, 476, 513, 678, 699, 728, 947, 965, 1002, 1119, 1135, 1149, 1190, 1307, 1344, 1404, 1472, 1489, 1503, 2938, 2957, 2991, 3008, 3022, 3050, 3242], '2de': [459, 948], 'Lange': [460, 878, 949, 1291], 'T.': [461, 879, 897, 950, 1292, 1509, 1515, 3028, 3034, 3332, 3334], 'Proc.': [462, 807, 951, 1068, 1293, 1459, 1582, 2978, 3069, 3314], 'Natl.': [463, 808, 952, 1069, 1294, 1460, 1583, 1754, 2979, 3070, 3315], 'Acad.': [464, 809, 953, 1070, 1295, 1461, 1584, 2980, 3071, 3316], 'Sci.': [465, 810, 954, 1071, 1296, 1462, 1585, 1971, 2981, 3072, 3317], 'U.': [466, 811, 955, 1072, 1297, 1463, 1575, 1586, 2982, 3062, 3073, 3318], 'S.': [467, 490, 668, 798, 812, 956, 979, 1073, 1171, 1298, 1321, 1464, 1517, 1587, 2983, 3036, 3074, 3246, 3288, 3319, 3367], 'A.': [468, 813, 957, 1074, 1299, 1465, 1493, 1588, 2984, 3012, 3075, 3140, 3175, 3320], '1994;': [469, 721, 778, 958, 1300, 1366, 1881, 2199, 2309, 3252], '91:': [470, 959, 1301], '2882-2885Crossref': [471, 960, 1302], '(295)': [474, 963, 1305], '3Harley': [477, 966, 1308], 'C.B.': [478, 666, 688, 707, 742, 967, 1175, 1309, 1352, 1476, 2185, 2995], 'Kim': [479, 968, 1310, 1957], 'N.W.': [480, 701, 969, 1311, 1346, 1958, 2179], 'Prowse': [481, 704, 970, 1312, 1349, 2182], 'K.R.': [482, 705, 971, 1313, 1350, 2183], 'Weinrich': [483, 716, 972, 1156, 1314, 1361, 1959, 2194], 'S.L.': [484, 717, 973, 1157, 1315, 1362, 1960, 2195], 'Hirsch': [485, 974, 1316], 'K.': [486, 975, 1035, 1103, 1317, 1507, 1634, 1962, 3026], 'West': [487, 708, 976, 1172, 1318, 1353, 2186], 'M.D.': [488, 709, 977, 1173, 1319, 1354, 2187], 'Bacchetti': [489, 667, 978, 1320], 'Hirte': [491, 980, 1322], 'H.W.': [492, 981, 1323, 1440, 1573, 2959, 3060], 'Counter': [493, 982, 1324], 'C.M.': [494, 656, 983, 1325], 'Greider': [495, 663, 685, 984, 1038, 1106, 1178, 1195, 1326, 1392, 1637, 2926], 'C.W.': [496, 515, 664, 686, 985, 1004, 1039, 1107, 1121, 1179, 1196, 1327, 1393, 1638, 2927], 'Wright': [497, 714, 986, 1328, 1359, 1965, 2192], 'W.E.': [498, 715, 987, 1329, 1360, 1966, 2193], 'Shay': [499, 718, 739, 988, 1330, 1363, 1967, 2196], 'J.M.': [500, 989, 1331], 'Cold': [501, 990, 1332], 'Spring': [502, 991, 1333], 'Harbor': [503, 992, 1334], 'Symp.': [504, 993, 1335], 'Quant.': [505, 994, 1336], 'Biol.': [506, 691, 831, 995, 1337, 1395, 2929, 3149, 3184, 3202, 3250], '1995;': [507, 746, 814, 832, 881, 996, 1041, 1109, 1183, 1338, 1640, 1972, 3150, 3185, 3203], '59:': [508, 997, 1140, 1339], '307-315Crossref': [509, 998, 1340], '(407)': [511, 1000, 1342], '4Greider': [514, 1003], '1996;': [519, 850, 1008, 1075, 1201, 1397, 1416, 1466, 1485, 1499, 1524, 1589, 2931, 2950, 2985, 3004, 3018, 3043, 3076], '65:': [520, 1009], '337-365Crossref': [521, 1010], '(905)': [524, 1013], 'Scholar).': [526, 620, 753, 918, 1015, 1082, 1208, 1373, 1531, 1596, 1761, 1888, 1978, 2206, 2316, 2517, 3083, 3210, 3260, 3387], 'Telomeres': [527], 'are': [528, 758, 2754], 'defined': [529], 'as': [530, 636, 1219, 1257, 1381, 1851, 1871, 1952, 2133, 2709, 2756], 'all': [534], 'eukaryotic': [535], 'chromosomes': [536, 557], 'comprising': [537], 'an': [538, 1256, 1788, 2329, 2535, 2699, 2708], 'array': [539], 'tandem': [541], 'repeats': [542], 'hexanucleotide': [545], '5′-TTAGGG-3′': [546], 'its': [548, 2553, 2900], 'binding': [549, 3345], 'proteins.': [550], 'nucleoprotein': [552], 'structures': [553], 'to': [555, 562, 570, 649, 1094, 1222, 2169, 2225, 2364, 2499, 2649, 2679, 2682, 2685, 2716, 3163, 3353], 'protect': [556], 'against': [558, 2586], 'exonucleases': [559], 'ligases,': [561], 'prevent': [563], 'activation': [565], 'DNA-damage': [567], 'checkpoints,': [568], 'counter': [571], 'loss': [573], 'terminal': [575], 'segments': [577], 'occurs': [579, 2781], 'when': [580], 'linear': [581, 632], 'replicated.': [584], 'Mutation': [585], 'repeat,': [588], 'however,': [589, 1251], 'blocks': [590], 'chromosome': [591], 'separation': [592], 'suggesting': [593, 2543, 2692, 2907], 'regulatory': [595, 2889, 3166], 'telomeres': [598, 634, 1230, 1289], 'anaphase': [600], 'mitosis': [601], '(5Kirk': [602], 'K.E.': [603], 'Harmon': [604], 'B.P.': [605], 'Reichardt': [606], 'I.K.': [607], 'Sedat': [608], 'J.W.': [609, 719, 740, 1364, 1748, 1968, 2197], 'Blackburn': [610, 1122], 'Science.': [612, 720, 880, 910, 1182, 1365, 1880, 2198, 2308, 3234], '1997;': [613, 911], '275:': [614, 912], '1478-1481Crossref': [615], '(189)': [618], 'Since': [621, 1615], 'conventional': [622], 'polymerases': [624], 'cannot': [625], 'replicate': [626, 1223], 'very': [628], '5′': [629], 'end': [630], 'DNA,': [633], 'shorten': [635], 'each': [640, 1232, 2012, 2039, 2289], 'somatic': [646, 1244], 'cells,': [647, 2784], 'contributing': [648], '(6Counter': [655], 'Avilion': [657, 1158], 'A.A.': [658, 1159, 1746], 'LeFeuvre': [659], 'C.E.': [660], 'Stewart': [661], 'N.G.': [662], 'Harley': [665, 687, 706, 741, 1174, 1351, 2184], 'EMBO': [669], 'J.': [670, 689, 806, 874, 1065, 1151, 1169, 1413, 1753, 2947, 3147, 3182, 3200, 3229, 3244, 3249, 3335], '11:': [672], '1921-1929Crossref': [673], '(1930)': [676], '7Levy': [679], 'M.Z.': [680], 'Allsopp': [681, 1166], 'R.C.': [682, 730, 1167], 'Futcher': [683], 'A.B.': [684], 'Mol.': [690, 829, 1394, 2928], '225:': [693], '951-960Crossref': [694], '(892)': [697], '8Kim': [700, 1345], 'Piatyszek': [702, 737, 1347, 2180], 'M.A.': [703, 738, 1192, 1348, 1956, 2181], 'Ho': [710, 1355, 2188], 'P.L.': [711, 1356, 2189], 'Coviello': [712, 1357, 2190], 'G.M.': [713, 1358, 2191], '266:': [722, 1367, 2200], '2011-2015Crossref': [723, 1368, 2201], '(6550)': [726, 1371, 2204], '9Allsopp': [729], 'Chang': [731, 1164], 'E.': [732, 1165, 1505, 1964, 3024, 3193, 3365], 'Kashefi-Aazam': [733], 'M.': [734, 826, 1194, 1519, 1569, 3038, 3056, 3313, 3373, 3375], 'Rogaev': [735], 'E.I.': [736], 'Exp.': [743, 1414, 2948], 'Cell': [744, 1801, 1970, 3148, 3183, 3201], 'Res.': [745, 1484, 1522, 3003, 3041], '220:': [747], '194-200Crossref': [748], '(453)': [751], 'However,': [754], 'several': [755], 'specialized': [756], 'proteins': [757, 793, 2890, 3092], 'involved': [759, 2599, 2755, 3119, 3405], 'metabolism,': [765], 'including': [766, 2427], 'yeast': [768], 'double': [769], 'strand': [770, 791], 'telomere-binding': [771, 792, 861], 'Rap1': [773], '(10Shore': [774], 'D.': [775, 870, 1198, 1491, 3010, 3371], 'Trends': [776], 'Genet.': [777, 1200], '10:': [779, 851, 1500, 3019], '408-412Abstract': [780], 'Full': [781, 1044, 1112, 1128, 1142, 1643, 3255, 3299, 3380], 'Text': [782, 1045, 1113, 1129, 1143, 1644, 3256, 3300, 3381], 'PDF': [783, 1046, 1114, 1130, 1144, 1645, 3257, 3301, 3382], '(263)': [786], 'Scholar)': [788, 1051], 'single': [790], 'Rlf6p': [794], '(11Konkel': [795], 'L.M.': [796], 'Enomoto': [797], 'Chamberlain': [799], 'E.M.': [800], 'McCune-Zierath': [801], 'P.': [802, 876, 1497, 2506, 3016, 3138, 3173], 'Iyadurai': [803], 'S.J.': [804, 1744], 'Berman': [805], '92:': [815, 1467, 2986], '5558-5562Crossref': [816], '(34)': [819], 'Scholar),': [821, 839, 857, 888, 1423, 1650, 3157, 3328], 'Cdc13': [822], '(12Garvik': [823], 'B.': [824, 868, 1181, 3142, 3177], 'Carson': [825], 'Hartwell': [827], 'L.': [828, 865, 895], 'Cell.': [830, 1040, 1108, 1124, 1138, 1396, 1639, 2930, 3295, 3376], '15:': [833], '6128-6138Crossref': [834], '(559)': [837], 'Est1': [841], '(13VirtaPearlman': [842], 'V.': [843, 847, 899, 3195], 'Morris': [844], 'D.K.': [845], 'Lundblad': [846], 'Genes': [848], 'Dev.': [849], '3094-3104Crossref': [852], '(141)': [855], 'duplex': [860], 'TRF': [863], '(14Chong': [864], 'van': [866], 'Steensel': [867], 'Broccoli': [869], 'Erdjument-Bromage': [871], 'H.': [872], 'Hanish': [873], 'Tempst': [875], 'de': [877, 1285, 2091], '270:': [882], '1663-1667Crossref': [883], '(619)': [886], 'telomerase-associated': [891], 'TP1': [893], '(15Harrington': [894], 'McPhail': [896], 'Mar': [898], 'Zhou': [900], 'W.': [901], 'Oulton': [902], 'R.': [903, 1037, 1105, 1458, 1567, 1581, 1636, 2977, 3054, 3068, 3309], 'Bass': [904], 'M.B.': [905], 'Arruda': [906], 'I.': [907], 'Robinson': [908, 1878, 2306], 'M.O.': [909], '973-977Crossref': [913], '(630)': [916], 'Telomerase,': [919], 'determinant': [922], 'length,': [925], 'complex': [929, 1621, 2424], 'specific': [930, 2584], 'synthesis': [934, 1287, 2904], '(1Blackburn': [935], 'It': [1016, 3388], 'composed': [1018], 'two': [1020, 1625], 'subunits': [1022], '95': [1024], 'kDa': [1025, 1028, 1055, 1058], '80': [1027], 'ciliate': [1031, 1061], 'Tetrahymena': [1032], 'thermophila': [1033], '(16Collins': [1034, 1102, 1633], 'Kobayashi': [1036, 1104, 1635], '81:': [1042, 1110, 1641], '677-686Abstract': [1043, 1111, 1642], '(243)': [1049, 1117, 1648], '120': [1054], '43': [1057], 'Euplotes': [1062], 'aediculatus': [1063], '(17Lingner': [1064], 'Cech': [1066], 'T.R.': [1067], '93:': [1076, 1590, 3077], '10712-10717Crossref': [1077], '(228)': [1080], 'While': [1083], '95-kDa': [1085], 'subunit': [1086, 1092, 2589, 3216], 'binds': [1087, 1093, 2498], 'substrate': [1088, 2008], 'oligonucleotides,': [1089], '80-kDa': [1091], 'RNA': [1097, 1217], 'component': [1098], '159': [1100], 'nucleotides': [1101], '18Greider': [1120], '1987;': [1125], '51:': [1126], '887-988Abstract': [1127], '(847)': [1133], '19Morin': [1136], 'G.B.': [1137], '1989;': [1139, 2510], '521-529Abstract': [1141], '(1376)': [1147], '20Feng': [1150], 'Funk': [1152], 'W.D.': [1153], 'Wang': [1154], 'S.S.': [1155], 'Chiu': [1160], 'C.P.': [1161], 'Adams': [1162], 'R.R.': [1163], 'Yu': [1168], 'Le': [1170], 'Andrews': [1176], 'W.H.': [1177], 'Villeporteau': [1180], '269:': [1184, 3253], '1236-1241Crossref': [1185], '(2079)': [1188], '21Blasco': [1191], 'Rizen': [1193], 'Hanahan': [1197], 'Nat.': [1199], '12:': [1202], '200-204Crossref': [1203], '(287)': [1206], 'Thus,': [1209], 'uses': [1211], 'portion': [1213], 'this': [1215, 2237, 2718, 2727], 'internal': [1216], 'moiety': [1218], 'template': [1221], 'telomeres.': [1224], 'Consistent': [1225], 'division,': [1235], 'below': [1239], 'detectable': [1240], 'most': [1247], 'malignancies,': [1250], 'activated': [1254], 'unknown': [1259], 'mechanism.': [1260], 'This': [1261, 2558, 2836], 'suggests': [1262], 'only': [1264], 'may': [1268, 2415, 2461, 2912, 3403, 3424], 'be': [1269, 2170, 2231, 2418, 3404, 3425], 'marker': [1271], 'malignancy': [1273], 'also': [1275, 2560], 'crucial': [1276], 'unlimited': [1278], 'tumor': [1282, 3273, 3401], 'through': [1284, 1716, 2698, 2858, 2920], 'novo': [1286, 2092], '(2de': [1290], 'Recent': [1374], 'studies': [1375, 2223, 3114], 'indicate': [1376], 'increases': [1380], 'T': [1384], 'enter': [1386], 'cycle': [1389, 3171], '(22Buchkovich': [1390, 2924], 'K.J.': [1391, 2925], '7:': [1398, 2932], '1443-1454Crossref': [1399, 2933], '(202)': [1402, 2936], '23Weng': [1405, 2939], 'N.P.': [1406, 2940], 'Levine': [1407, 2941], 'B.L.': [1408, 2942, 3231, 3286], 'June': [1409, 2943], 'C.H.': [1410, 2944], 'Hodes': [1411, 2945], 'R.J.': [1412, 2946], 'Med.': [1415, 2949], '183:': [1417, 2951], '2471-2479Crossref': [1418, 2952], '(365)': [1421, 2955], 'promyelocytic': [1430], 'leukemic': [1431], 'HL60': [1432], 'repressed': [1435], 'differentiation': [1438], '(24Sharma': [1439], 'Sokoloski': [1441, 1576, 2960, 3063], 'J.A.': [1442, 1577, 2961, 3064], 'Perez': [1443, 2962], 'J.R.': [1444, 2963], 'Maltese': [1445, 2964], 'J.Y.': [1446, 2965], 'Sartorelli': [1447, 2966], 'A.C.': [1448, 2967], 'Stein': [1449, 2968], 'C.A.': [1450, 2969], 'Nichols': [1451, 2970], 'G.': [1452, 2971, 3307], 'Khaled': [1453, 2972], 'Z.': [1454, 2973], 'Telang': [1455, 2974], 'N.T.': [1456, 2975], 'Narayanan': [1457, 1580, 2976, 3067], '12343-12346Crossref': [1468, 2987], '(299)': [1470, 2989], '25Bestilny': [1473, 2992], 'L.J.': [1474, 2993], 'Brown': [1475, 2994], 'Miura': [1477, 2996], 'Y.': [1478, 1511, 2997, 3030], 'Roberstson': [1479, 2998], 'L.D.': [1480, 2999], 'Riabowol': [1481, 3000], 'K.T.': [1482, 3001], 'Cancer': [1483, 1755, 3002], '56:': [1486, 3005], '3796-3802PubMed': [1487, 3006], '26Xu': [1490, 3009], 'Gruber': [1492, 3011], 'Peterson': [1494, 3013], 'C.': [1495, 3014, 3311, 3369], 'Pisa': [1496, 3015], 'Leukemia.': [1498, 3017], '1354-1357PubMed': [1501, 3020], '27Savoysky': [1504, 3023], 'Yoshida': [1506, 1516, 3025, 3035], 'Ohtomo': [1508, 3027], 'Yamaguchi': [1510, 3029], 'Akamatsu': [1512, 3031], 'K.I.': [1513, 3032], 'Yamazaki': [1514, 3033], 'Tsuchiya': [1518, 3037], 'Biophys.': [1521, 3040], 'Commun.': [1523, 3042], '226:': [1525, 3044], '329-334Crossref': [1526, 3045], '(94)': [1529, 3048], 'cycle-dependent': [1546], 'manner,': [1547], 'S': [1554], 'phase': [1555, 1563], 'decreased': [1557], 'G2/M': [1562], '(28Zhu': [1564], 'X.L.': [1565, 3052], 'Kumar': [1566, 3053], 'Mandal': [1568, 3055], 'Sharma': [1570, 1572, 3057, 3059], 'N.': [1571, 3058], 'Dhingra': [1574, 3061], 'Hsiao': [1578, 3065], 'R.S.': [1579, 3066], '6091-6095Crossref': [1591, 3078], '(245)': [1594, 3081], 'growth': [1605], 'development': [1607], 'molecular': [1613, 2758, 2909], 'switch.': [1614], 'vertebrate': [1616], 'at': [1623, 1787, 1798, 1839, 1987, 2154, 2345, 2832, 2879, 3127, 3268], 'least': [1624, 2880, 3269], 'components': [1627, 2468, 2886], 'containing': [1628, 1939, 1998], 'multiple': [1629], 'potential': [1630, 3097, 3427], 'sites': [1632], 'we': [1651, 2239, 2785], 'tested': [1652], 'hypothesis': [1654, 2594], 'might': [1658, 2230], 'play': [1659, 3164], 'function.': [1664], 'specifically': [1679], '(PP2A).': [1685], '1The': [1686], 'abbreviations': [1687], 'used': [1688], 'are:': [1689], 'PP2A,': [1690], '2A;': [1693], 'CHAPS,': [1694], '3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic': [1695], 'acid;': [1696], 'ATPγS,': [1697, 2671], 'adenosine': [1698], '5′-O-(thiotriphosphate).': [1699], 'effect': [1701, 2330, 2430, 2567, 2837], 'turn': [1706], 'blocked': [1707], 'acid': [1710, 1846, 2529, 2795, 2814, 2820], 'reversed': [1712], 'kinase(s),': [1719], 'indicating': [1720], 'reversible': [1722, 2915], 'dephosphorylation.': [1731], 'Human': [1732], 'been': [1738, 2167, 2216, 3161], 'described': [1739, 1872, 1953], 'earlier': [1740], '(29Whitehead': [1741], 'R.H.': [1742], 'Quirk': [1743], 'Vitali': [1745], 'Funder': [1747], 'Sutherland': [1749], 'R.L.': [1750], 'Murphy': [1751], 'L.C.': [1752], 'Inst.': [1756], '1984;': [1757], '73:': [1758], '643-648PubMed': [1759], 'maintained': [1765], 'medium': [1768], 'RPMI': [1770], '1640': [1771], 'supplemented': [1772], 'fetal': [1774], 'calf': [1775], 'serum': [1776], '(10%),': [1777], 'insulin': [1778], '(0.6': [1779], 'μg/ml),': [1780, 1783], 'hydrocortisone': [1781], '(1': [1782, 1847, 2815], 'galactose': [1785], '(0.1%)': [1786], 'enclosed': [1789], 'humidified': [1790], 'atmosphere': [1791], '95%': [1793], 'O2': [1794], '5%': [1796], 'CO2': [1797], '37': [1799], '°C.': [1800], 'nuclei': [1802], 'isolated': [1804], 'centrifugation': [1806], '(3000': [1807], '×': [1808, 1833], 'g)': [1809], 'after': [1810, 2286, 2575, 2636, 2720, 2827], 'homogenization': [1811], 'Teflon/glass': [1817], 'homogenizer': [1818], '(10': [1819], 'ml),': [1820], 'cytosolic': [1823], 'membrane': [1825, 2276, 2361, 2391], 'fractions': [1826, 1931, 2393], 'separated': [1828], 'further': [1829, 2607, 2652], 'ultracentrifugation': [1831], '(100,000': [1832], 'g).': [1834], 'some': [1836], 'experiments,': [1837, 2624], '80%': [1840], 'confluence': [1841], 'treated': [1843, 2786], 'μm,': [1848], 'Calbiochem)': [1850], 'indicated.': [1852], '(>95%': [1854], 'pure)': [1855], 'obtained': [1857], 'Biomol': [1859], 'Research': [1860], 'Laboratories': [1861], '(Plymouth': [1862], 'Meeting,': [1863], 'PA)': [1864], 'or': [1865, 1932, 2152, 2469, 2887, 3399], 'partially': [1866], 'purified': [1867], 'rat': [1869], 'liver': [1870], 'previously': [1873, 1954], '(30Liu': [1874, 2302], 'J.-P.': [1875, 2303], 'Sim': [1876, 2304], 'A.T.R.': [1877, 2305], 'P.J.': [1879, 2307], '265:': [1882, 2310], '970-973Crossref': [1883, 2311], '(183)': [1886, 2314], 'PP1': [1889], 'PP2B': [1891], 'UBI': [1894], '(Lake': [1895], 'Placid,': [1896], 'NY).': [1897], 'Taq': [1898], 'polymerase,': [1900], 'dNTP,': [1901], 'T4': [1903, 2034], 'gene': [1904, 2035], '32': [1905, 2036], 'Boehringer': [1909], 'Mannheim.': [1910], '[α-32P]ATP': [1911], 'Amersham.': [1914], 'Gel': [1915], 'electrophoresis': [1916, 2095, 2125], 'reagents': [1917], 'equipment': [1919], 'Bio-Rad.': [1922], 'Telomerase': [1923, 2281, 2409], 'membrane,': [1927], 'cytosolic,': [1928], 'extracted': [1933, 2259], 'whole': [1935], 'buffer': [1938, 1997], '2.5%': [1940], 'CHAPS': [1941], 'determined': [1943, 2241], 'duplicate': [1945], 'slightly': [1948], 'modified': [1949], 'TRAP': [1950], 'assay': [1951], '(31Piatyszek': [1955], 'Hiyama': [1961, 1963], 'Methods': [1969], '17:': [1973], '1-16Crossref': [1974], '(396)': [1976], 'Briefly,': [1979], 'μg': [1981, 2005, 2032, 2051, 2148], 'incubated': [1986, 2630], '30': [1988, 2067, 2072, 2828], '°C': [1989, 2065, 2070, 2076, 2156], '20': [1991], 'min': [1992, 2159, 2829], '50-μl': [1995], 'reaction': [1996, 2040, 2063, 2086], '10': [1999, 2158, 2346], 'mm': [2000, 2020, 2023, 2026], 'Tris,': [2001], 'pH': [2002], '8.3,': [2003], '0.1': [2004, 2050], '(5′-AATCCGTCGAGCAGAGTT-3′),': [2009], '50': [2010, 2069], 'μm': [2011], 'deoxynucleoside': [2013], 'triphosphate,': [2014], '0.5': [2015], 'μCi': [2016], '[α-32P]dATP,': [2018], '1.5': [2019], 'MgCl2,': [2021], 'EGTA,': [2024], '68': [2025], 'KCl,': [2027], '0.05%': [2028], 'Tween': [2029], '20,': [2030], 'protein.': [2037], 'To': [2038, 2236, 2473, 2774], 'then': [2042, 2088, 2284], 'added': [2043], '2': [2044, 2147, 2336, 2351, 2541, 2689, 2743], 'units': [2045], 'ofTaq': [2046], 'polymerase': [2048, 2061, 2084], 'downstream': [2053], 'primer': [2054], 'CX': [2055], '(5′-CCCTTACCCTTACCCTTACCCTAA-3′),': [2056], 'followed': [2057, 2102, 2659], '31-cycle': [2060], 'chain': [2062, 2085], '(94': [2064], 's,': [2068, 2073, 2347], '72': [2075], '45': [2078], 's).': [2079], 'Twenty': [2080], 'μl': [2081], 'analyzed': [2089], 'synthesized32P-telomeres': [2093], '10%': [2098], 'non-denaturing': [2099, 2122], 'polyacrylamide': [2100, 2123], 'gel': [2101, 2124], 'overnight': [2104], 'exposure': [2105], 'autoradiography.': [2107], 'For': [2108, 2135], 'relative': [2109], 'quantification,': [2110], 'measured': [2114], 'scintillation': [2116], 'counting': [2117], '32P-telomeres': [2119], 'resolved': [2120], 'sliced': [2127], 'gels': [2130], 'autoradiographs': [2132], 'templates.': [2134], 'experimental': [2136], 'controls': [2137], 'assay,': [2141], 'treatment': [2142], 'RNase': [2150], 'A': [2151], 'heating': [2153], '90': [2155], 'routinely': [2161], 'included.': [2162], 'Inappropriate': [2163], 'has': [2166, 3160], 'found': [2168, 2802], 'associated': [2171, 2385], 'variety': [2174], 'cancers': [2177, 3411], '(8Kim': [2178], 'aim': [2220], 'these': [2222, 2621, 2807, 3085], 'test': [2226], 'whether': [2227], 'phosphorylation.': [2235], 'end,': [2238], 'effects': [2242], 'three': [2245, 3270], 'major': [2246], '(1,': [2250], '2A,': [2251, 2296], '2B)': [2253], 'Subcellular': [2266], 'fractionation': [2267], 'performed': [2273], 'nuclear,': [2275], 'particulate,': [2277], 'fractions.': [2280], 'examined': [2285], 'incubation': [2287, 2653], 'fraction': [2290, 2363], 'exogenous': [2292], '1,': [2295], 'under': [2299], 'dephosphorylation': [2300, 2464, 2597, 2687, 2721, 2753, 2779, 3419], 'conditions': [2301], 'Interestingly,': [2317], 'markedly': [2319, 2810], '(Fig.': [2326, 2376, 2401, 2540, 2688, 2742, 2817], 'A),': [2328, 2542], 'concentration-dependent': [2333, 2532], '(ED5010': [2334], '±': [2335], 'units,': [2337], 'Fig.': [2338], 'B)': [2340], 'rapid': [2342], '(significant': [2343], 'inhibition': [2344, 2349, 2434, 2477, 2519, 2554, 2602, 3393], 'complete': [2348], 'min;': [2352, 2635], 'Fig.1': [2353], 'C).': [2354, 2378], 'particulate': [2362, 2392], 'lesser': [2366], 'extent': [2367], 'than': [2368], 'appeared': [2372], 'inactive': [2373], 'cytosol': [2375, 2400], 'Substantial': [2379], '(45%)': [2389], '(38%),': [2394], 'compared': [2395], '17%': [2397], 'C)': [2403], 'different': [2412, 2797], 'subcellular': [2413], 'locations': [2414], 'thus': [2416, 2842, 3390], 'ultimately': [2417], 'achieved': [2419], 'balance': [2422], 'control': [2425, 2875], 'mechanisms,': [2426], 'PP2A.': [2432, 2723], 'specific,': [2442], 'since': [2443], 'neither': [2444], 'nor': [2448], 'affected': [2450], '(Fig.1': [2453], 'B).': [2454, 2744], 'reflect': [2462], 'direct': [2463, 3265], 'indirect': [2470], 'protein-protein': [2471], 'interactions.': [2472], 'verify': [2474], 'PP2A-induced': [2476], 'dephosphorylation,': [2483, 2857], 'coincubated': [2488], 'various': [2492], 'concentrations': [2493], 'catalytic': [2501, 2546, 2588, 3215], 'motif': [2502], '(32Cohen': [2505], '58:': [2511], '453-508Crossref': [2512], '(2156)': [2515], 'fashion,': [2533], 'ED50': [2536], '0.2': [2538], 'nm': [2539], 'required': [2551, 2898], 'activity.': [2557, 2619], 'supported': [2561, 2608], 'observation': [2564], 'avoided': [2574], 'absorbed': [2579], 'advance': [2581], 'antibody': [2585], '(data': [2590], 'shown).': [2592], 'correlation': [2611], 'between': [2612, 3090], 'reactivation': [2616, 2694, 2733, 3408], 'first': [2629], '3': [2634], 'addition': [2637], 'sodium': [2643], 'fluoride,': [2644], 'allowed': [2648], 'proceed': [2650], 'analysis.': [2663], 'back': [2678], 'equivalent': [2681], 'those': [2683], 'prior': [2684], 'B),': [2690], 'strongly': [2691], 'ATP': [2700], 'hydrolysis-dependent': [2701], 'mechanism': [2702, 2910], 'unidentified': [2711, 2859], 'likely': [2715, 2871], 'mediate': [2717], 'process': [2719], 'support': [2725], 'concept': [2728], 'phosphorylation,': [2731], 'kinase': [2739], 'H-7': [2741], 'data': [2746], 'unequivocally': [2747], 'switch': [2759], 'up-': [2761], 'down-regulating': [2763], 'determine': [2775], 'if': [2776], 'PP2A-mediated': [2778], 'event': [2780], 'periods': [2798], 'time': [2800], 'μm)': [2816], '3).': [2818], 'Okadaic': [2819], 'stimulation': [2821, 3416], 'seen': [2826], 'peaked': [2831], '2–3': [2833], 'h': [2834], '(Fig.3).': [2835], 'thein': [2845], 'vitro': [2846], '2A.': [2866], 'it': [2869, 3159], 'activity,': [2878], 'one': [2881], 'phosphorylated': [2892], 'cancer,': [2906], 'explain': [2913], 'cycles': [2923], '24Sharma': [2958], '28Zhu': [3051], 'link': [3089], 'target': [3098, 3266], 'controlling': [3102], 'therapy.': [3107], 'Several': [3108], 'lines': [3109], 'evidence': [3111], 'previous': [3113], 'process.': [3123], 'high': [3128], 'non-transformed': [3134], 'fibroblasts': [3136], '(33Turowski': [3137, 3172], 'Fernandez': [3139, 3174], 'Favre': [3141, 3176], 'Lamb': [3143, 3178], 'N.J.': [3144, 3179], 'Hemmings': [3145, 3180], 'B.A.': [3146, 3181], '129:': [3151, 3186], '397-410Crossref': [3152, 3187], '(136)': [3155, 3190], 'suggested': [3162], 'during': [3168], 'Scholar,34Sontag': [3192], 'Nunbhakdi-Craig': [3194], 'Bloom': [3196], 'G.S.': [3197], 'Mumby': [3198, 3312, 3374], 'M.C.': [3199], '128:': [3204], '1131-1144Crossref': [3205], '(296)': [3208], 'Tyrosine': [3211], 'receptor-linked': [3218], 'non-receptor': [3220], 'tyrosine': [3221], 'kinases': [3222], 'inhibits': [3223, 3355], '(35Chen': [3228], 'Martin': [3230, 3285], 'Brautigan': [3232, 3247, 3291], 'D.L.': [3233, 3248, 3292], '257:': [3236], '1261-1264Crossref': [3237], '(538)': [3240], '36Chen': [3243], 'Parsons': [3245], 'Chem.': [3251], '7957-7962Abstract': [3254], 'Moreover,': [3261], 'distinct': [3271], 'virus': [3274, 3277, 3280], 'families,': [3275], 'simian': [3276], '40,': [3278], 'polyoma': [3279], '(37Pallas': [3281], 'D.C.': [3282], 'Shahrik': [3283], 'L.K.': [3284], 'Jaspers': [3287], 'Miller': [3289], 'T.B.': [3290], 'Roberts': [3293], 'T.M.': [3294], '1990;': [3296, 3321], '60:': [3297], '167-176Abstract': [3298], '(457)': [3304], 'Scholar,38Walter': [3306], 'Ruediger': [3308], 'Slaughter': [3310], '87:': [3322], '2521-2525Crossref': [3323], '(159)': [3326], 'adenovirus': [3330], '(39Kleinberger': [3331], 'Shenk': [3333], 'Virol.': [3336], '1993;': [3337, 3377], '67:': [3338], '7556-7560Crossref': [3339], 'Scholar);': [3342], 'viral': [3348, 3400], 'small-t': [3351], 'antigen': [3352], 'stimulates': [3361], '(40Sontag': [3364], 'Fedorov': [3366], 'Kamibayashi': [3368], 'Robbins': [3370], 'Cobb': [3372], '75:': [3378], '887-897Abstract': [3379], '(461)': [3385], 'conceivable': [3391], 'signals': [3398], 'antigens': [3402], 'certain': [3410], 'pharmacological': [3415], 'therapeutic': [3428], 'significance.': [3429], 'We': [3430], 'thank': [3431], 'Bob': [3432], 'Whitehead': [3433], 'supplying': [3435], 'line,': [3440], 'Michael': [3441], 'Berndt,': [3442], 'Alex': [3443], 'Bobik,': [3444], 'Noel': [3445], 'Fidge,': [3446], 'Ban-Hock': [3447], 'Toh,': [3448], 'Elizabeth': [3450], 'Woodcock': [3451], 'their': [3453], 'advice,': [3454], 'Zhi-Yong': [3456], 'Yang': [3457], 'technical': [3459], 'assistance.': [3460]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2018513924', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2025-01-07T20:52:24.953718', 'created_date': '2016-06-24'}