Abstract: All endogenous opioid peptides isolated belong to one of three peptide families, each deriving from a distinct precursor molecule: pro-opiomelanocortin is the common precursor for β-endorphin and ACTH; pro-enkephalin A is the common precursor for Met-enkephalin and Leu-enkephalin, as well as for several opioid peptides such as peptide E, BAM-22P, -20P, -12P and peptide F; pro-enkephalin B is another precursor for Leu-enkephalin and for a variety of opioid peptides such as dynorphin 1–17 and α-neo-endorphin. This article provides a short overview of our present knowledge of processing, distribution and receptor selectivity in these three opioid peptide systems.
Publication Year: 1983
Publication Date: 1983-01-01
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 177
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot