Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2017947609', 'doi': 'https://doi.org/10.1042/bj20080762', 'title': 'KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cells', 'display_name': 'KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cells', 'publication_year': 2008, 'publication_date': '2008-09-10', 'ids': {'openalex': 'https://openalex.org/W2017947609', 'doi': 'https://doi.org/10.1042/bj20080762', 'mag': '2017947609', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18774944'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj20080762', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100430448', 'display_name': 'Min‐Young Lee', 'orcid': 'https://orcid.org/0000-0003-3396-7632'}, 'institutions': [{'id': 'https://openalex.org/I193775966', 'display_name': 'Yonsei University', 'ror': 'https://ror.org/01wjejq96', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I193775966']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Min-Young Lee', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea', 'institution_ids': ['https://openalex.org/I193775966']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030861100', 'display_name': 'Jong‐Seok Moon', 'orcid': 'https://orcid.org/0000-0002-2537-7854'}, 'institutions': [{'id': 'https://openalex.org/I193775966', 'display_name': 'Yonsei University', 'ror': 'https://ror.org/01wjejq96', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I193775966']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jong-Seok Moon', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea', 'institution_ids': ['https://openalex.org/I193775966']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103567456', 'display_name': 'Sahng Wook Park', 'orcid': 'https://orcid.org/0000-0002-9594-7074'}, 'institutions': [{'id': 'https://openalex.org/I193775966', 'display_name': 'Yonsei University', 'ror': 'https://ror.org/01wjejq96', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I193775966']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sahng\xa0Wook Park', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea', 'institution_ids': ['https://openalex.org/I193775966']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103050342', 'display_name': 'Yookyung Koh', 'orcid': 'https://orcid.org/0000-0002-4022-4012'}, 'institutions': [{'id': 'https://openalex.org/I193775966', 'display_name': 'Yonsei University', 'ror': 'https://ror.org/01wjejq96', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I193775966']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Yoo-kyung Koh', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea', 'institution_ids': ['https://openalex.org/I193775966']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049685258', 'display_name': 'Yong‐Ho Ahn', 'orcid': 'https://orcid.org/0000-0002-4133-0757'}, 'institutions': [{'id': 'https://openalex.org/I193775966', 'display_name': 'Yonsei University', 'ror': 'https://ror.org/01wjejq96', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I193775966']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Yong-Ho Ahn', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea', 'institution_ids': ['https://openalex.org/I193775966']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5019900739', 'display_name': 'Kyung‐Sup Kim', 'orcid': 'https://orcid.org/0000-0001-8483-8537'}, 'institutions': [{'id': 'https://openalex.org/I193775966', 'display_name': 'Yonsei University', 'ror': 'https://ror.org/01wjejq96', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I193775966']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Kyung-Sup Kim', 'raw_affiliation_strings': ['Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry and Molecular Biology, Brain Korea 2 1 Project for Medical Science, Institute of Genetic Science, Center for Chronic Disease Research, Yonsei University, College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea', 'institution_ids': ['https://openalex.org/I193775966']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.708, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 36, 'citation_normalized_percentile': {'value': 0.828623, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '417', 'issue': '1', 'first_page': '313', 'last_page': '322'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13426', 'display_name': 'Kruppel-like factors research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13426', 'display_name': 'Kruppel-like factors research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12465', 'display_name': 'Cancer, Lipids, and Metabolism', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9845, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2779723316', 'wikidata': 'https://www.wikidata.org/wiki/Q6459234', 'display_name': 'LNCaP', 'level': 4, 'score': 0.8692812}, {'id': 'https://openalex.org/C48289651', 'wikidata': 'https://www.wikidata.org/wiki/Q106916817', 'display_name': 'Fatty acid synthase', 'level': 3, 'score': 0.78997654}, {'id': 'https://openalex.org/C85051948', 'wikidata': 'https://www.wikidata.org/wiki/Q416064', 'display_name': 'Sterol regulatory element-binding protein', 'level': 4, 'score': 0.61687565}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5517983}, {'id': 'https://openalex.org/C119056186', 'wikidata': 'https://www.wikidata.org/wiki/Q1431332', 'display_name': 'Gene silencing', 'level': 3, 'score': 0.51860976}, {'id': 'https://openalex.org/C61367390', 'wikidata': 'https://www.wikidata.org/wiki/Q416601', 'display_name': 'Androgen receptor', 'level': 4, 'score': 0.4910636}, {'id': 'https://openalex.org/C22615655', 'wikidata': 'https://www.wikidata.org/wiki/Q203221', 'display_name': 'Small interfering RNA', 'level': 4, 'score': 0.48634177}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.4624548}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.45502928}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.4090207}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3576738}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3330055}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.28698212}, {'id': 'https://openalex.org/C54009773', 'wikidata': 'https://www.wikidata.org/wiki/Q1429031', 'display_name': 'Transfection', 'level': 3, 'score': 0.24651372}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17787099}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.15357831}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.15178663}, {'id': 'https://openalex.org/C4733338', 'wikidata': 'https://www.wikidata.org/wiki/Q2792936', 'display_name': 'Lipid metabolism', 'level': 2, 'score': 0.101897985}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000728', 'descriptor_name': 'Androgens', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D064429', 'descriptor_name': 'Fatty Acid Synthases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D051741', 'descriptor_name': 'Kruppel-Like Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D051780', 'descriptor_name': 'Sterol Regulatory Element Binding Protein 1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000728', 'descriptor_name': 'Androgens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064429', 'descriptor_name': 'Fatty Acid Synthases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D064429', 'descriptor_name': 'Fatty Acid Synthases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047468', 'descriptor_name': 'Immunoprecipitation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007438', 'descriptor_name': 'Introns', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D007438', 'descriptor_name': 'Introns', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051741', 'descriptor_name': 'Kruppel-Like Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051741', 'descriptor_name': 'Kruppel-Like Transcription Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020133', 'descriptor_name': 'Reverse Transcriptase Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051780', 'descriptor_name': 'Sterol Regulatory Element Binding Protein 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051780', 'descriptor_name': 'Sterol Regulatory Element Binding Protein 1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj20080762', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18774944', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.64, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1844022234', 'https://openalex.org/W1898639226', 'https://openalex.org/W1965734230', 'https://openalex.org/W1971286169', 'https://openalex.org/W1982517502', 'https://openalex.org/W1985933433', 'https://openalex.org/W1991861950', 'https://openalex.org/W1993343317', 'https://openalex.org/W1995139299', 'https://openalex.org/W1995571423', 'https://openalex.org/W1995889915', 'https://openalex.org/W2000566591', 'https://openalex.org/W2004181770', 'https://openalex.org/W2008543341', 'https://openalex.org/W2012220368', 'https://openalex.org/W2016539451', 'https://openalex.org/W2017330272', 'https://openalex.org/W2028405970', 'https://openalex.org/W2032691440', 'https://openalex.org/W2032869210', 'https://openalex.org/W2037071441', 'https://openalex.org/W2037409829', 'https://openalex.org/W2038183822', 'https://openalex.org/W2039501269', 'https://openalex.org/W2039971229', 'https://openalex.org/W2048272531', 'https://openalex.org/W2048548143', 'https://openalex.org/W2049481073', 'https://openalex.org/W2064129352', 'https://openalex.org/W2064365978', 'https://openalex.org/W2077328356', 'https://openalex.org/W2085559675', 'https://openalex.org/W2089126365', 'https://openalex.org/W2093265805', 'https://openalex.org/W2095358593', 'https://openalex.org/W2097632838', 'https://openalex.org/W2100705255', 'https://openalex.org/W2109165881', 'https://openalex.org/W2122002354', 'https://openalex.org/W2126590121', 'https://openalex.org/W2131734657', 'https://openalex.org/W2133383018', 'https://openalex.org/W2135501426', 'https://openalex.org/W2137724838', 'https://openalex.org/W2138282645', 'https://openalex.org/W2140089594', 'https://openalex.org/W2140500564', 'https://openalex.org/W2143661421', 'https://openalex.org/W2146544786', 'https://openalex.org/W2146607058', 'https://openalex.org/W2150796809', 'https://openalex.org/W2161020200', 'https://openalex.org/W4252021281', 'https://openalex.org/W564597390'], 'related_works': ['https://openalex.org/W4362487847', 'https://openalex.org/W2909034820', 'https://openalex.org/W2356769105', 'https://openalex.org/W2347235584', 'https://openalex.org/W2110155536', 'https://openalex.org/W2095873383', 'https://openalex.org/W2093382902', 'https://openalex.org/W2076586151', 'https://openalex.org/W2063882679', 'https://openalex.org/W2005564231'], 'abstract_inverted_index': {'KLF5': [0, 34, 67, 79, 100, 112, 174, 203], '(Krüppel-like': [1], 'factor': [2, 8], '5)': [3], 'is': [4, 196], 'a': [5, 11, 37, 74], 'zinc-finger': [6], 'transcription': [7], 'that': [9, 33, 96, 136, 192], 'plays': [10], 'critical': [12], 'role': [13], 'in': [14, 21, 55, 88, 101, 183, 211], 'the': [15, 28, 41, 56, 85, 97, 125, 129, 138, 142, 160, 178, 193, 199], 'regulation': [16, 140], 'of': [17, 43, 66, 99, 111, 128, 141, 180, 202], 'cellular': [18], 'signalling': [19], 'involved': [20], 'cell': [22, 61], 'proliferation,': [23], 'differentiation': [24], 'and': [25, 83, 124, 149, 168, 204], 'oncogenesis.': [26], 'In': [27], 'present': [29], 'study,': [30], 'we': [31], 'showed': [32], 'acts': [35], 'as': [36, 153], 'key': [38], 'regulator': [39], 'controlling': [40], 'expression': [42, 98], 'FASN': [44, 89, 107, 118, 130, 194], '(fatty': [45], 'acid': [46], 'synthase)': [47], 'through': [48], 'an': [49], 'interaction': [50], 'with': [51, 73], 'SREBP-1': [52, 82], '(sterol-regulatory-element-binding': [53], 'protein-1)': [54], 'androgen-dependent': [57, 212], 'LNCaP': [58, 102], 'prostate': [59, 103, 213], 'cancer': [60, 104, 214], 'line.': [62], 'The': [63, 92, 120], 'mRNA': [64], 'level': [65], 'increased': [68], 'when': [69], 'cells': [70, 105], 'were': [71], 'treated': [72], 'synthetic': [75], 'androgen,': [76], 'R1881.': [77], 'Furthermore,': [78], 'bound': [80], 'to': [81, 173, 177], 'enhanced': [84, 106], 'SREBP-1-mediated': [86], 'increase': [87], 'promoter': [90, 122, 185], 'activity.': [91], 'results': [93, 190], 'also': [94], 'demonstrated': [95], 'expression,': [108, 175], 'whereas': [109], 'silencing': [110], 'by': [113, 144, 198, 209], 'small': [114], 'interfering': [115], 'RNA': [116], 'down-regulated': [117], 'expression.': [119], 'proximal': [121], 'region': [123], 'first': [126], 'intron': [127], 'gene': [131, 143, 195], 'contain': [132], 'multiple': [133], 'CACCC': [134, 181], 'elements': [135, 182], 'mediate': [137], 'transcriptional': [139], 'KLF5.': [145], 'However,': [146], 'other': [147], 'lipogenic': [148], 'cholesterogenic': [150], 'genes,': [151], 'such': [152], 'those': [154], 'encoding': [155], 'acetyl-CoA': [156], 'carboxylase,': [157], 'ATP-citrate': [158], 'lyase,': [159], 'LDL': [161], '(low-density': [162], 'lipoprotein)': [163], 'receptor,': [164], 'HMG-CoA': [165, 169], '(3-hydroxy-3-methylglutaryl-CoA)': [166], 'synthase': [167], 'reductase': [170], 'are': [171], 'irresponsive': [172], 'owing': [176], 'absence': [179], 'their': [184], 'regions.': [186], 'Taken': [187], 'together,': [188], 'these': [189], 'suggest': [191], 'activated': [197], 'synergistic': [200], 'action': [201], 'SREBP-1,': [205], 'which': [206], 'was': [207], 'induced': [208], 'androgen': [210], 'cells.': [215]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2017947609', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-13T15:39:09.703757', 'created_date': '2016-06-24'}