Title: Influence of n‐3 fatty acids on blood lipids in normal subjects
Abstract: Abstract. The effects of consuming oils providing alpha‐linolenic (ALA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids were studied in healthy volunteers. A blunted increase in plasma triglyceride was observed in subjects given a test meal containing fish oil compared with olive oil; cholesterol concentrations were not increased; increases in EPA and DHA were seen in all lipid fractions. In longer term supplementation studies, ALA increased EPA, but not DHA in plasma phospholipids; preformed EPA was more effective. The proportion of EPA in platelet lipids increased in a dose dependent manner. EPA or DHA, but not ALA, decreased plasma triglyceride and VLDL cholesterol concentrations. Supplements containing DHA increased HDL and HDL 2 cholesterol and LDL apoB. Total cholesterol and LDL cholesterol concentrations were unaltered.
Publication Year: 1989
Publication Date: 1989-12-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 53
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