Title: LITHIATION OF AN IMIDAZOLE NUCLEOSIDE AT THE C-5 POSITION. SYNTHESIS OF 3-DEAZAGUANOSINE FROM URIDINE
Abstract: Abstract 3-Deazaguanosine, an antiviral nucleoside, was synthesized from uridine via lithiation of a C-2 protected imidazole nucleoside, which has been devised as a method for introducing various functionalities to the C-5 position. This furnished the first successful example of the conversion of a naturally occurring nucleoside to a deazapurine nucleoside.
Publication Year: 1985
Publication Date: 1985-05-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 6
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