Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2017445997', 'doi': 'https://doi.org/10.1016/j.juro.2009.03.085', 'title': 'Selective Pharmacological Blockade of the TRPV1 Receptor Suppresses Sensory Reflexes of the Rodent Bladder', 'display_name': 'Selective Pharmacological Blockade of the TRPV1 Receptor Suppresses Sensory Reflexes of the Rodent Bladder', 'publication_year': 2009, 'publication_date': '2009-06-19', 'ids': {'openalex': 'https://openalex.org/W2017445997', 'doi': 'https://doi.org/10.1016/j.juro.2009.03.085', 'mag': '2017445997', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19539322'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2009.03.085', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5045211537', 'display_name': 'Joseph S. Cefalu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joseph S. Cefalu', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075890863', 'display_name': 'Marlene A. Guillon', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Marlene A. Guillon', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083024139', 'display_name': 'Leah R. Burbach', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Leah R. Burbach', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080934158', 'display_name': 'Quan‐Ming Zhu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Quan-Ming Zhu', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110060319', 'display_name': 'Dong‐Qing Hu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dong-Qing Hu', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055792330', 'display_name': 'Meghan J. Ho', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Meghan J. Ho', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065067986', 'display_name': 'Anthony Ford', 'orcid': 'https://orcid.org/0000-0001-8618-0273'}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anthony P.D.W. Ford', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112198581', 'display_name': 'Philip A. Nunn', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Philip A. Nunn', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5029575711', 'display_name': 'Debra A. Cockayne', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210124598', 'display_name': 'Palo Alto Institute', 'ror': 'https://ror.org/02xf01n45', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210124598']}, {'id': 'https://openalex.org/I129302853', 'display_name': 'Roche (United States)', 'ror': 'https://ror.org/011qkaj49', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I118019719', 'https://openalex.org/I129302853']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Debra A. Cockayne', 'raw_affiliation_strings': ['Roche Palo Alto, Palo Alto, California'], 'affiliations': [{'raw_affiliation_string': 'Roche Palo Alto, Palo Alto, California', 'institution_ids': ['https://openalex.org/I4210124598', 'https://openalex.org/I129302853']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.01, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.718007, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '182', 'issue': '2', 'first_page': '776', 'last_page': '785'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11204', 'display_name': 'Ion Channels and Receptors', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10279', 'display_name': 'Urinary Bladder and Prostate Research', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2748', 'display_name': 'Urology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12048', 'display_name': 'Microencapsulation and Drying Processes', 'score': 0.9595, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/urination', 'display_name': 'Urination', 'score': 0.9114435}, {'id': 'https://openalex.org/keywords/capsaicin', 'display_name': 'Capsaicin', 'score': 0.85669595}, {'id': 'https://openalex.org/keywords/resiniferatoxin', 'display_name': 'Resiniferatoxin', 'score': 0.7199935}, {'id': 'https://openalex.org/keywords/detrusor-muscle', 'display_name': 'Detrusor muscle', 'score': 0.6444441}], 'concepts': [{'id': 'https://openalex.org/C175768497', 'wikidata': 'https://www.wikidata.org/wiki/Q105726', 'display_name': 'Urination', 'level': 3, 'score': 0.9114435}, {'id': 'https://openalex.org/C2780051329', 'wikidata': 'https://www.wikidata.org/wiki/Q273169', 'display_name': 'Capsaicin', 'level': 3, 'score': 0.85669595}, {'id': 'https://openalex.org/C83974742', 'wikidata': 'https://www.wikidata.org/wiki/Q179405', 'display_name': 'Reflex', 'level': 2, 'score': 0.7333377}, {'id': 'https://openalex.org/C2776354303', 'wikidata': 'https://www.wikidata.org/wiki/Q3277888', 'display_name': 'Resiniferatoxin', 'level': 5, 'score': 0.7199935}, {'id': 'https://openalex.org/C160145004', 'wikidata': 'https://www.wikidata.org/wiki/Q413209', 'display_name': 'TRPV1', 'level': 4, 'score': 0.7155003}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.67819}, {'id': 'https://openalex.org/C2780616540', 'wikidata': 'https://www.wikidata.org/wiki/Q568055', 'display_name': 'Detrusor muscle', 'level': 3, 'score': 0.6444441}, {'id': 'https://openalex.org/C2779762690', 'wikidata': 'https://www.wikidata.org/wiki/Q9382', 'display_name': 'Urinary bladder', 'level': 2, 'score': 0.5859057}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.5473778}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.3734694}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.35459238}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3292725}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.30527043}, {'id': 'https://openalex.org/C77411442', 'wikidata': 'https://www.wikidata.org/wiki/Q181100', 'display_name': 'Urinary system', 'level': 2, 'score': 0.18861383}, {'id': 'https://openalex.org/C155164980', 'wikidata': 'https://www.wikidata.org/wiki/Q304043', 'display_name': 'Transient receptor potential channel', 'level': 3, 'score': 0.07230425}], 'mesh': [{'descriptor_ui': 'D000631', 'descriptor_name': 'Aminopyridines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D010879', 'descriptor_name': 'Piperazines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D012018', 'descriptor_name': 'Reflex', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D013890', 'descriptor_name': 'Thiourea', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D001743', 'descriptor_name': 'Urinary Bladder', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000631', 'descriptor_name': 'Aminopyridines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002211', 'descriptor_name': 'Capsaicin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010879', 'descriptor_name': 'Piperazines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012018', 'descriptor_name': 'Reflex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013890', 'descriptor_name': 'Thiourea', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013890', 'descriptor_name': 'Thiourea', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D001743', 'descriptor_name': 'Urinary Bladder', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2009.03.085', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19539322', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.5, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W1490106730', 'https://openalex.org/W1965004534', 'https://openalex.org/W1965847104', 'https://openalex.org/W1971456679', 'https://openalex.org/W1971566600', 'https://openalex.org/W2001341161', 'https://openalex.org/W2006469490', 'https://openalex.org/W2021033497', 'https://openalex.org/W2022332945', 'https://openalex.org/W2024255262', 'https://openalex.org/W2024424546', 'https://openalex.org/W2028462700', 'https://openalex.org/W2032539918', 'https://openalex.org/W2039913291', 'https://openalex.org/W2050781058', 'https://openalex.org/W2057487165', 'https://openalex.org/W2068168026', 'https://openalex.org/W2081996521', 'https://openalex.org/W2094323845', 'https://openalex.org/W2097142746', 'https://openalex.org/W2107057334', 'https://openalex.org/W2107988902', 'https://openalex.org/W2127780645', 'https://openalex.org/W2127993895'], 'related_works': ['https://openalex.org/W3024106091', 'https://openalex.org/W2108536849', 'https://openalex.org/W2094558143', 'https://openalex.org/W2093379263', 'https://openalex.org/W2078158703', 'https://openalex.org/W2076315294', 'https://openalex.org/W2038631083', 'https://openalex.org/W2017445997', 'https://openalex.org/W2017417965', 'https://openalex.org/W1986012407'], 'abstract_inverted_index': {'No': [0], 'AccessJournal': [1], 'of': [2, 9, 16, 223, 230, 274, 355, 378, 404, 445, 448, 453, 528, 584, 603, 621, 629, 698, 722, 736, 764, 790, 846, 923, 956, 959, 987, 990, 1014, 1089, 1113], 'UrologyInvestigative': [3], 'Urology1': [4], 'Aug': [5], '2009Selective': [6], 'Pharmacological': [7, 734], 'Blockade': [8], 'the': [10, 17, 220, 245, 286, 326, 361, 368, 383, 400, 405, 409, 446, 454, 473, 487, 509, 514, 533, 561, 582, 627, 723, 737, 749, 791, 798, 820, 867, 894, 920], 'TRPV1': [11, 224, 237, 394, 449, 483, 506, 604, 655, 683, 705, 738, 812, 831], 'Receptor': [12], 'Suppresses': [13], 'Sensory': [14], 'Reflexes': [15], 'Rodent': [18], 'Bladder': [19, 677, 1082, 1106], 'Joseph': [20, 46, 1143], 'S.': [21, 47, 49, 1144], 'Cefalu,': [22], 'Marlene': [23, 64, 1158], 'A.': [24, 40, 44, 65, 67, 169, 171, 188, 190, 1159, 1247, 1262], 'Guillon,': [25], 'Leah': [26, 82, 1173], 'R.': [27, 83, 85, 1174], 'Burbach,': [28], 'Quan-Ming': [29, 100, 1188], 'Zhu,': [30], 'Dong-Qing': [31, 116, 1202], 'Hu,': [32], 'Meghan': [33, 132, 1216], 'J.': [34, 133, 135, 1217], 'Ho,': [35], 'Anthony': [36, 150, 1231], 'P.D.W.': [37, 151, 153, 1232], 'Ford,': [38], 'Philip': [39, 168, 1246], 'Nunn,': [41], 'and': [42, 186, 234, 240, 265, 269, 282, 320, 339, 367, 382, 397, 436, 459, 467, 492, 588, 632, 660, 682, 695, 745, 761, 887, 995, 1019, 1031, 1071, 1080, 1104, 1108, 1110], 'Debra': [43, 187, 1261], 'Cockayne': [45, 191, 1263], 'CefaluJoseph': [48], 'Cefalu': [50, 1145], 'Financial': [51, 69, 87, 103, 119, 137, 155, 173, 192, 1146, 1161, 1176, 1190, 1204, 1219, 1234, 1249, 1264], 'interest': [52, 70, 88, 104, 120, 138, 156, 174, 193, 1147, 1162, 1177, 1191, 1205, 1220, 1235, 1250, 1265], 'and/or': [53, 71, 89, 105, 121, 139, 157, 175, 194, 1148, 1163, 1178, 1192, 1206, 1221, 1236, 1251, 1266], 'other': [54, 72, 90, 106, 122, 140, 158, 176, 195, 1149, 1164, 1179, 1193, 1207, 1222, 1237, 1252, 1267], 'relationship': [55, 73, 91, 107, 123, 141, 159, 177, 196, 1150, 1165, 1180, 1194, 1208, 1223, 1238, 1253, 1268], 'with': [56, 74, 92, 108, 124, 142, 160, 178, 197, 375, 827, 1151, 1166, 1181, 1195, 1209, 1224, 1239, 1254, 1269], 'Roche.': [57, 75, 93, 109, 125, 143, 161, 179, 198, 1152, 1167, 1182, 1196, 1210, 1225, 1240, 1255, 1270], 'More': [58, 76, 94, 110, 126, 144, 162, 180, 199, 1153, 1168, 1183, 1197, 1211, 1226, 1241, 1256, 1271], 'articles': [59, 77, 95, 111, 127, 145, 163, 181, 200, 1154, 1169, 1184, 1198, 1212, 1227, 1242, 1257, 1272], 'by': [60, 78, 96, 112, 128, 146, 164, 182, 201, 388, 423, 433, 539, 860, 866, 919, 966, 1022, 1049, 1134, 1155, 1170, 1185, 1199, 1213, 1228, 1243, 1258, 1273], 'this': [61, 79, 97, 113, 129, 147, 165, 183, 202, 258, 1156, 1171, 1186, 1200, 1214, 1229, 1244, 1259, 1274], 'author': [62, 80, 98, 114, 130, 148, 166, 184, 203, 1157, 1172, 1187, 1201, 1215, 1230, 1245, 1260, 1275], ',': [63, 81, 99, 115, 131, 149, 167, 185], 'GuillonMarlene': [66], 'Guillon': [68, 1160], 'BurbachLeah': [84], 'Burbach': [86, 1175], 'ZhuQuan-Ming': [101], 'Zhu': [102, 1189], 'HuDong-Qing': [117], 'Hu': [118, 1203], 'HoMeghan': [134], 'Ho': [136, 1218], 'FordAnthony': [152], 'Ford': [154, 1233], 'NunnPhilip': [170], 'Nunn': [172, 1248], 'CockayneDebra': [189], 'View': [204], 'All': [205, 1277], 'Author': [206], 'Informationhttps://doi.org/10.1016/j.juro.2009.03.085AboutFull': [207], 'TextPDF': [208], 'ToolsAdd': [209], 'to': [210, 333, 420, 626, 635, 885], 'favoritesDownload': [211], 'CitationsTrack': [212], 'CitationsPermissionsReprints': [213], 'ShareFacebookLinked': [214], 'InTwitterEmail': [215], 'Abstract': [216], 'Purpose:': [217], 'We': [218], 'investigated': [219], 'pharmacological': [221], 'effect': [222, 344, 418], 'antagonists': [225, 238, 395, 721], 'in': [226, 244, 257, 260, 266, 285, 295, 325, 335, 352, 363, 370, 408, 450, 470, 486, 508, 532, 544, 558, 591, 610, 640, 664, 680, 743, 746, 748, 776, 801, 815, 819, 889, 925, 973, 998], 'anesthetized': [227, 246, 287, 410], 'rodent': [228], 'models': [229, 273, 354], 'bladder': [231, 304, 322, 371, 556, 586, 589, 630, 658, 662, 823, 842, 993], 'function.': [232], 'Materials': [233], 'Methods:': [235], 'The': [236, 393, 526, 881, 1012], 'JNJ17203212': [239, 253, 281, 301, 340, 348, 396, 427], 'JYL1421': [241, 283, 308, 398, 741], 'were': [242], 'evaluated': [243, 256], 'rat': [247, 267, 288, 411, 821, 895], 'volume': [248, 289, 319, 327, 366, 412], 'induced': [249, 276, 290, 328, 357, 387, 413, 432, 538, 918, 965], 'micturition': [250, 291, 298, 317, 329, 364, 406, 414, 455, 799], 'reflex': [251, 292, 330, 407, 415, 456, 800], 'model.': [252, 416], 'was': [254, 349], 'further': [255, 343], 'model': [259, 293, 331], 'capsaicin': [261, 268, 346, 424, 435, 474, 886, 924], '(Sigma®)': [262], 'desensitized': [263], 'rats,': [264], 'mouse': [270, 1015], 'citric': [271, 390, 438], 'acid': [272, 700, 766, 970], 'irritant': [275, 356], 'detrusor': [277, 358, 430, 963], 'overactivity.': [278], 'Results:': [279], 'Systemic': [280], 'administration': [284, 922], 'resulted': [294], 'an': [296], 'increased': [297, 315, 399, 607], 'threshold': [299, 318, 365, 401], 'volume.': [300], 'also': [302, 350, 428], 'decreased': [303, 321, 384], 'contraction': [305, 323, 372], 'amplitude': [306, 324, 373], 'but': [307], 'had': [309], 'no': [310, 342], 'effect.': [311], 'Capsaicin': [312], 'desensitization': [313, 958], 'significantly': [314], 'baseline': [316], 'compared': [332], 'those': [334], 'sham': [336], 'treated': [337], 'controls': [338], 'produced': [341], 'after': [345], 'desensitization.': [347], 'effective': [351], '2': [353, 481], 'overactivity,': [359], 'preventing': [360], 'decrease': [362], 'increase': [369], 'observed': [374], 'intravesical': [376, 389, 434, 437, 921, 967, 988], 'instillation': [377, 989], '10': [379, 675], 'μM': [380], 'capsaicin,': [381, 968], 'voiding': [385], 'interval': [386], 'acid.': [391, 439], 'Conclusions:': [392], 'for': [402, 581, 941], 'activation': [403, 620], 'This': [417], 'appeared': [419], 'be': [421], 'mediated': [422, 859], 'sensitive': [425], 'afferents.': [426], 'inhibited': [429], 'overactivity': [431, 590, 659], 'These': [440], 'data': [441], 'extend': [442], 'our': [443], 'understanding': [444], 'role': [447, 527], 'sensory': [451], 'modulation': [452], 'under': [457], 'nonirritant': [458], 'inflammatory': [460, 1023], 'conditions.': [461], 'References': [462], '1': [463, 578, 624, 774, 1030], ':': [464, 482, 503, 525, 553, 572, 601, 618, 649, 676, 693, 718, 733, 759, 788, 811, 840, 856, 880, 906, 936, 954, 985, 1011], 'Impaired': [465], 'nociception': [466], 'pain': [468], 'sensation': [469], 'mice': [471, 559], 'lacking': [472, 560], 'receptor.': [475, 725], 'Science2000;': [476], '288:': [477], '306.': [478], 'Google': [479, 500, 522, 550, 569, 598, 615, 646, 673, 690, 715, 730, 756, 785, 808, 837, 853, 877, 903, 933, 951, 982, 1008, 1040], 'Scholar': [480, 501, 523, 551, 570, 599, 616, 647, 674, 691, 716, 731, 757, 786, 809, 838, 854, 878, 904, 934, 952, 983, 1009, 1041], '(vanilloid': [484], 'receptor)': [485], 'urinary': [488, 535, 555, 896, 943], 'tract:': [489], 'expression,': [490], 'function': [491, 557, 994], 'clinical': [493], 'applications.': [494], 'Naunyn-Schmied': [495, 517], 'Arch': [496, 518, 929, 978], 'Pharmacol2006;': [497, 850, 948], '373:': [498], '287.': [499], '3': [502], 'Where': [504], 'is': [505, 579, 813], 'expressed': [507], 'bladder,': [510], 'do': [511], 'we': [512], 'see': [513], 'real': [515], 'channel?.': [516], 'Pharmacol2009;': [519], '379:': [520], '421.': [521], '4': [524], 'capsaicin-sensitive': [529, 960], 'afferent': [530, 678, 1017], 'fibers': [531, 1018], 'lower': [534, 942], 'tract': [536, 944], 'dysfunction': [537], 'chronic': [540], 'spinal': [541, 636], 'cord': [542], 'injury': [543], 'rats.': [545, 802, 975, 1002], 'Exper': [546], 'Neurol2004;': [547], '187:': [548], '445.': [549], '5': [552], 'Altered': [554], 'vanilloid': [562, 576, 622, 707, 724, 773, 861, 1029], 'receptor': [563, 574, 623, 708, 739, 771, 794, 913, 1027], 'TRPV1.': [564], 'Nat': [565], 'Neurosci2002;': [566], '5:': [567], '856.': [568], '6': [571], 'Transient': [573], 'potential': [575, 772, 1028], 'subfamily': [577], 'essential': [580], 'generation': [583], 'noxious': [585, 661], 'input': [587, 663], 'cystitis.': [592, 641], 'J': [593, 642, 668, 686, 710, 752, 779, 803, 873, 899, 947, 1003, 1036], 'Urol2007;': [594, 804], '177:': [595], '1537.': [596], 'Link,': [597, 672, 807, 1007], '7': [600], 'Lack': [602], 'inhibits': [605], 'cystitis-induced': [606], 'mechanical': [608], 'sensitivity': [609, 679], 'mice.': [611, 685], 'Pain2008;': [612], '139:': [613], '158.': [614], '8': [617], 'Anandamide-evoked': [619], 'contributes': [625], 'development': [628], 'hyperreflexia': [631], 'nociceptive': [633, 996], 'transmission': [634], 'dorsal': [637], 'horn': [638], 'neurons': [639], 'Neurosci2004;': [643], '24:': [644], '11253.': [645], '9': [648], 'GRC-6211,': [650], 'a': [651, 702, 769, 825, 829, 909], 'new': [652, 830], 'oral': [653], 'specific': [654], 'antagonist,': [656, 870, 914], 'decreases': [657], 'cystitis': [665], 'animal': [666], 'models.': [667], 'Urol2009;': [669], '181:': [670], '379.': [671], 'wild-type': [681], 'knockout': [684], 'Physiol2007;': [687], '583:': [688], '663.': [689], '11': [692], 'Identification': [694], 'biological': [696], 'evaluation': [697], '4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic': [699], '(5-trifluoromethylpyridin-2-yl)amide,': [701], 'high': [703, 868], 'affinity': [704, 720, 869], '(VR1)': [706], 'antagonist.': [709], 'Med': [711], 'Chem2005;': [712], '48:': [713], '1857.': [714], '12': [717], 'High': [719], 'Mol': [726], 'Pharmacol2002;': [727], '62:': [728], '947.': [729], '13': [732], 'characterization': [735], 'antagonist': [740, 775, 795], '(SC0030)': [742], 'vitro': [744], 'vivo': [747], 'rat.': [750], 'Eur': [751, 898], 'Pharmacol2005;': [753], '517:': [754], '35.': [755], '14': [758], 'Pharmacology': [760], 'antitussive': [762], 'efficacy': [763], '4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic': [765], '(5-trifluoromethyl-pyridin-2-yl)-amide': [767], '(JNJ17203212),': [768], 'transient': [770, 1026], 'guinea': [777], 'pigs.': [778], 'Pharmacol': [780], 'Exp': [781], 'Ther2007;': [782], '323:': [783], '665.': [784], '15': [787], 'Effects': [789, 955, 986], 'selective': [792], 'prostacyclin': [793], 'RO3244019': [796], 'on': [797, 962, 992], '178:': [805], '2683.': [806], '16': [810], 'involved': [814], 'stretch-evoked': [816], 'contractile': [817, 883], 'changes': [818], 'autonomous': [822], 'model:': [824], 'study': [826], 'piperine,': [828], 'agonist.': [832], 'Neurourol': [833], 'Urodyn2007;': [834], '26:': [835], '440.': [836], '17': [839], 'Urinary': [841], 'urothelium:': [843], 'Molecular': [844], 'sensors': [845], 'chemical/thermal/mechanical': [847], 'stimuli.': [848], 'Vas': [849], '45:': [851], '221.': [852], '18': [855], 'Neurogenic': [857], 'responses': [858, 884, 917], 'receptor-1': [862], '(TRPV1)': [863], 'are': [864], 'blocked': [865], 'iodo-resiniferatoxin.': [871], 'Br': [872, 946], 'Pharmacol2003;': [874, 979], '138:': [875], '977.': [876], '19': [879], 'differential': [882], 'anandamide': [888], 'muscle': [890], 'strips': [891], 'isolated': [892], 'from': [893], 'bladder.': [897], 'Pharmacol2007;': [900], '570:': [901], '182.': [902, 932], '20': [905], 'MEN': [907], '11,420,': [908], 'peptide': [910], 'tachykinin': [911], 'NK2': [912], 'reduces': [915], 'motor': [916], 'vivo.': [926], 'Naunyn': [927, 976], 'Schmied': [928, 977], 'Pharmacol1997;': [930], '356:': [931], '21': [935], 'Purinoceptors': [937], 'as': [938], 'therapeutic': [939], 'targets': [940], 'dysfunction.': [945], '147:': [949], 'S132.': [950], '22': [953], 'resiniferatoxin': [957, 991], 'afferents': [961], 'over-activity': [964], 'acetic': [969], 'or': [971], 'ATP': [972], 'conscious': [974, 1001], '367:': [980], '473.': [981], '23': [984], 'behavior': [997], 'freely': [999], 'moving,': [1000], 'Urol2008;': [1004], '179:': [1005], '359.': [1006], '24': [1010], 'mechanosensitivity': [1013], 'colon': [1016], 'their': [1020], 'sensitization': [1021], 'mediators': [1024], 'require': [1025], 'acid-sensing': [1032], 'ion': [1033], 'channel': [1034], '3.': [1035], 'Neurosci2005;': [1037], '25:': [1038], '10981.': [1039], 'Roche': [1042], 'Palo': [1043, 1045], 'Alto,': [1044, 1046], 'California©': [1047], '2009': [1048, 1133], 'American': [1050, 1135], 'Urological': [1051, 1136], 'AssociationFiguresReferencesRelatedDetailsCited': [1052], 'byKitagawa': [1053], 'Y,': [1054], 'Wada': [1055], 'M,': [1056, 1064, 1066], 'Kanehisa': [1057], 'T,': [1058], 'Miyai': [1059], 'A,': [1060, 1068], 'Usui': [1061], 'K,': [1062], 'Maekawa': [1063], 'Sakata': [1065], 'Matsuo': [1067], 'Hayashi': [1069], 'M': [1070, 1073], 'Matsushita': [1072], '(2018)': [1074, 1101], 'JTS-653': [1075], 'Blocks': [1076], 'Afferent': [1077], 'Nerve': [1078], 'Firing': [1079], 'Attenuates': [1081], 'Overactivity': [1083], 'Without': [1084], 'Affecting': [1085], 'Normal': [1086], 'Voiding': [1087, 1102], 'FunctionJournal': [1088], 'Urology,': [1090, 1114], 'VOL.': [1091, 1115], '189,': [1092], 'NO.': [1093, 1117], '3,': [1094], '(1137-1146),': [1095], 'Online': [1096, 1120], 'publication': [1097, 1121], 'date:': [1098, 1122], '1-Mar-2013.Wein': [1099], 'A': [1100], 'Function': [1103], 'Dysfunction,': [1105], 'Physiology': [1107], 'Pharmacology,': [1109], 'Female': [1111], 'UrologyJournal': [1112], '184,': [1116], '2,': [1118], '(800-803),': [1119], '1-Aug-2010.': [1123], 'Volume': [1124], '182Issue': [1125], '2August': [1126], '2009Page:': [1127], '776-785': [1128], 'Advertisement': [1129, 1278], 'Copyright': [1130], '&': [1131], 'Permissions©': [1132], 'AssociationKeywordsTRPV1': [1137], 'proteinurinary': [1138], 'bladdermousecapsaicinTRPV1': [1139], 'proteinratvisceral': [1140], 'afferentsMetricsAuthor': [1141], 'Information': [1142], 'Expand': [1276], 'PDF': [1279], 'downloadLoading': [1280], '...': [1281]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2017445997', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-14T03:13:33.864110', 'created_date': '2016-06-24'}