Publication Information

{'id': 'https://openalex.org/W2017111743', 'doi': 'https://doi.org/10.2174/1874082000701010007', 'title': 'Cell Growth in Response to Mechanical Stiffness is Affected by Neuron- Astroglia Interactions', 'display_name': 'Cell Growth in Response to Mechanical Stiffness is Affected by Neuron- Astroglia Interactions', 'publication_year': 2007, 'publication_date': '2007-12-19', 'ids': {'openalex': 'https://openalex.org/W2017111743', 'doi': 'https://doi.org/10.2174/1874082000701010007', 'mag': '2017111743'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2174/1874082000701010007', 'pdf_url': 'http://benthamopen.com/contents/pdf/TONEURJ/TONEURJ-1-7.pdf', 'source': {'id': 'https://openalex.org/S183485564', 'display_name': 'The Open Neuroscience Journal', 'issn_l': '1874-0820', 'issn': ['1874-0820'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320079', 'host_organization_name': 'Bentham Science Publishers', 'host_organization_lineage': ['https://openalex.org/P4310320079'], 'host_organization_lineage_names': ['Bentham Science Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://benthamopen.com/contents/pdf/TONEURJ/TONEURJ-1-7.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5038945591', 'display_name': 'Xue Jiang', 'orcid': 'https://orcid.org/0000-0001-9639-8655'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xue Jiang', 'raw_affiliation_strings': ['Department of Biomedical Engineering,'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Engineering,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021429494', 'display_name': 'Penelope C. Georges', 'orcid': 'https://orcid.org/0000-0001-5599-7061'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Penelope C. Georges', 'raw_affiliation_strings': ['Department of Biomedical Engineering,', 'Department of Cell Biology and Neuroscience and'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Neuroscience and', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Biomedical Engineering,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101632518', 'display_name': 'Baogang Li', 'orcid': 'https://orcid.org/0000-0002-3430-7508'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Baogang Li', 'raw_affiliation_strings': ['Department of Cell Biology and Neuroscience and'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Neuroscience and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042454026', 'display_name': 'Yangzhou Du', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yangzhou Du', 'raw_affiliation_strings': ['Department of Cell Biology and Neuroscience and'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Neuroscience and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001830923', 'display_name': 'Melinda K. Kutzing', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I102322142', 'display_name': 'Rutgers, The State University of New Jersey', 'ror': 'https://ror.org/05vt9qd57', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I102322142']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Melinda K. Kutzing', 'raw_affiliation_strings': ['Biomedical Engineering Graduate Program, Rutgers University, Piscataway, New Jersey 08854, USA', 'Department of Biomedical Engineering,'], 'affiliations': [{'raw_affiliation_string': 'Biomedical Engineering Graduate Program, Rutgers University, Piscataway, New Jersey 08854, USA', 'institution_ids': ['https://openalex.org/I102322142']}, {'raw_affiliation_string': 'Department of Biomedical Engineering,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072082377', 'display_name': 'Michelle L. Previtera', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Michelle L. Previtera', 'raw_affiliation_strings': ['Department of Cell Biology and Neuroscience and', 'Molecular Biosciences Graduate Program,'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Neuroscience and', 'institution_ids': []}, {'raw_affiliation_string': 'Molecular Biosciences Graduate Program,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060446703', 'display_name': 'Noshir A. Langrana', 'orcid': 'https://orcid.org/0000-0003-1236-5851'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Noshir A. Langrana', 'raw_affiliation_strings': ['Department of Biomedical Engineering,'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Engineering,', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5008785953', 'display_name': 'Bonnie L. Firestein', 'orcid': 'https://orcid.org/0000-0002-1679-3565'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Bonnie L. Firestein', 'raw_affiliation_strings': ['Department of Cell Biology and Neuroscience and'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Neuroscience and', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.639, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 32, 'citation_normalized_percentile': {'value': 0.749437, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '1', 'issue': '1', 'first_page': '7', 'last_page': '14'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10379', 'display_name': 'Cellular Mechanics and Interactions', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10379', 'display_name': 'Cellular Mechanics and Interactions', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11190', 'display_name': '3D Printing in Biomedical Research', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10059', 'display_name': 'Bone Tissue Engineering Materials', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/neurite', 'display_name': 'Neurite', 'score': 0.6943684}], 'concepts': [{'id': 'https://openalex.org/C2777542381', 'wikidata': 'https://www.wikidata.org/wiki/Q502961', 'display_name': 'Astrocyte', 'level': 3, 'score': 0.767277}, {'id': 'https://openalex.org/C113246987', 'wikidata': 'https://www.wikidata.org/wiki/Q1534415', 'display_name': 'Neurite', 'level': 3, 'score': 0.6943684}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.6059247}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.5262555}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.48983166}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.46930292}, {'id': 'https://openalex.org/C2778794669', 'wikidata': 'https://www.wikidata.org/wiki/Q43054', 'display_name': 'Neuron', 'level': 2, 'score': 0.46021616}, {'id': 'https://openalex.org/C189165786', 'wikidata': 'https://www.wikidata.org/wiki/Q193825', 'display_name': 'Extracellular matrix', 'level': 2, 'score': 0.45655814}, {'id': 'https://openalex.org/C2780775167', 'wikidata': 'https://www.wikidata.org/wiki/Q9606', 'display_name': 'Spinal cord', 'level': 2, 'score': 0.43604457}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.41222465}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3769624}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.33005524}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.31338304}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.30659252}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.294883}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.25220054}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.2174/1874082000701010007', 'pdf_url': 'http://benthamopen.com/contents/pdf/TONEURJ/TONEURJ-1-7.pdf', 'source': {'id': 'https://openalex.org/S183485564', 'display_name': 'The Open Neuroscience Journal', 'issn_l': '1874-0820', 'issn': ['1874-0820'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320079', 'host_organization_name': 'Bentham Science Publishers', 'host_organization_lineage': ['https://openalex.org/P4310320079'], 'host_organization_lineage_names': ['Bentham Science Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2174/1874082000701010007', 'pdf_url': 'http://benthamopen.com/contents/pdf/TONEURJ/TONEURJ-1-7.pdf', 'source': {'id': 'https://openalex.org/S183485564', 'display_name': 'The Open Neuroscience Journal', 'issn_l': '1874-0820', 'issn': ['1874-0820'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320079', 'host_organization_name': 'Bentham Science Publishers', 'host_organization_lineage': ['https://openalex.org/P4310320079'], 'host_organization_lineage_names': ['Bentham Science Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W134723953', 'https://openalex.org/W1506658790', 'https://openalex.org/W1649382389', 'https://openalex.org/W1896952141', 'https://openalex.org/W1973089587', 'https://openalex.org/W1974170815', 'https://openalex.org/W1976265701', 'https://openalex.org/W1982130586', 'https://openalex.org/W1984724534', 'https://openalex.org/W1991349806', 'https://openalex.org/W2002582091', 'https://openalex.org/W2006482556', 'https://openalex.org/W2013763910', 'https://openalex.org/W2020676683', 'https://openalex.org/W2033087883', 'https://openalex.org/W2042408662', 'https://openalex.org/W2051842637', 'https://openalex.org/W2059994807', 'https://openalex.org/W2090073018', 'https://openalex.org/W2095301611', 'https://openalex.org/W2102084306', 'https://openalex.org/W2123450039', 'https://openalex.org/W2134208433', 'https://openalex.org/W2134257943', 'https://openalex.org/W2144007430', 'https://openalex.org/W2158429263', 'https://openalex.org/W2161853058', 'https://openalex.org/W2170473622', 'https://openalex.org/W45698776'], 'related_works': ['https://openalex.org/W4224793487', 'https://openalex.org/W3137920716', 'https://openalex.org/W2896971219', 'https://openalex.org/W2116447221', 'https://openalex.org/W2094467039', 'https://openalex.org/W2037133501', 'https://openalex.org/W1976265701', 'https://openalex.org/W1971502696', 'https://openalex.org/W1930507751', 'https://openalex.org/W1896952141'], 'abstract_inverted_index': {'Cell': [0], 'adhesion': [1, 62, 71], 'and': [2, 49, 76, 129, 211, 213], 'morphology': [3], 'are': [4, 176], 'affected': [5], 'by': [6, 142, 218], 'the': [7, 11, 19, 111, 116, 119, 203, 206, 221], 'mechanical': [8, 200], 'properties': [9], 'of': [10, 40, 44, 113, 118, 122, 132, 152, 166, 195, 202, 208], 'extracellular': [12], 'matrix.Using': [13], 'polyacrylamide': [14], 'gels': [15, 173], 'as': [16], 'cell': [17, 138, 223], 'substrates,': [18], 'cellular': [20], 'response': [21, 207, 215], 'to': [22, 57, 99, 124, 146], 'substrate': [23, 204], 'compliance': [24], 'was': [25, 81, 89, 178], 'investigated': [26, 110], 'in': [27, 115, 148], 'pure': [28, 30, 48, 68], 'neuronal,': [29], 'astroglial,': [31], 'or': [32], 'mixed': [33, 50, 103, 150], 'co-cultures.Substrates': [34], 'used': [35], 'spanned': [36], 'a': [37, 149, 191], 'large': [38], 'range': [39], 'stiffnesses': [41], 'including': [42], 'that': [43, 183, 199], 'brain': [45], 'tissue.In': [46], 'both': [47, 209], 'cultures,': [51], 'immature': [52], '(vimentin+)': [53], 'astroglia': [54], 'adhered': [55], 'best': [56], 'stiffest': [58], 'gels.Mature': [59], '(GFAP+)': [60], 'astrocyte': [61], 'peaked': [63], 'on': [64, 91, 159, 168, 171, 185], 'intermediate': [65, 74, 92], 'stiffness,': [66], 'while': [67, 102], 'GFAP+': [69], 'astroglial': [70], 'displayed': [72], 'no': [73, 106], 'preference': [75], 'increased': [77], 'with': [78, 83, 182], 'stiffness.Neurite': [79], 'length': [80], 'constant': [82], 'stiffness;': [84], 'however,': [85], 'primary': [86], 'dendrite': [87], 'number': [88, 194], 'lowest': [90], 'gels.Pure': [93], 'neuronal': [94], 'cultures': [95, 104], 'were': [96], 'more': [97], 'adherent': [98], 'hard': [100, 172], 'gels,': [101, 187], 'had': [105], 'stiffness': [107, 114, 201], 'preference.Furthermore,': [108], 'we': [109], 'role': [112], 'modulation': [117], 'neurotoxic': [120, 164], 'effect': [121, 165], 'glutamate.Exposure': [123], 'two': [125, 222], 'glutamate': [126, 145, 167], 'concentrations': [127], '(500': [128], '1000': [130], 'M)': [131], 'cultured': [133, 170], 'spinal': [134, 153], 'cord': [135, 154], 'neurons': [136, 147, 169, 210], 'induced': [137], 'death.The': [139], 'damage': [140], 'elicited': [141], '500': [143], 'm': [144], 'culture': [151], 'cells': [155], 'is': [156, 190, 216], 'most': [157], 'severe': [158], 'soft': [160, 186], '300': [161], 'Pa': [162], 'gels.The': [163], 'where': [174, 188], 'astrocytes': [175], 'present': [177], 'strongly': [179], 'attenuated': [180], 'compared': [181], 'observed': [184], 'there': [189], 'relatively': [192], 'low': [193], 'astrocytes.Our': [196], 'data': [197], 'suggest': [198], 'affects': [205], 'astroglia,': [212], 'this': [214], 'varied': [217], 'interaction': [219], 'between': [220], 'types.': [224]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2017111743', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-13T20:06:04.305029', 'created_date': '2016-06-24'}