Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2016419664', 'doi': 'https://doi.org/10.1002/1097-4547(20001201)62:5<750::aid-jnr15>3.0.co;2-8', 'title': 'Sex-dependent changes in blood-brain barrier permeability and brain NA+,K+ATPase activity in rats following acute water intoxication', 'display_name': 'Sex-dependent changes in blood-brain barrier permeability and brain NA+,K+ATPase activity in rats following acute water intoxication', 'publication_year': 2000, 'publication_date': '2000-01-01', 'ids': {'openalex': 'https://openalex.org/W2016419664', 'doi': 'https://doi.org/10.1002/1097-4547(20001201)62:5<750::aid-jnr15>3.0.co;2-8', 'mag': '2016419664', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11104514'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1097-4547(20001201)62:5<750::aid-jnr15>3.0.co;2-8', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S76417895', 'display_name': 'Journal of Neuroscience Research', 'issn_l': '0360-4012', 'issn': ['0360-4012', '1097-4547'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5098411517', 'display_name': 'Baria �zta', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Baria �zta?', 'raw_affiliation_strings': ['Department of Physiology Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082167959', 'display_name': 'Hikmet Koçak', 'orcid': 'https://orcid.org/0000-0003-1720-9102'}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Hikmet Ko�ak', 'raw_affiliation_strings': ['Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5098286558', 'display_name': 'Pernur �ner', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Pernur �ner', 'raw_affiliation_strings': ['Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey', 'institution_ids': ['https://openalex.org/I67581229']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5097226122', 'display_name': 'Mutlu K���k', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I67581229', 'display_name': 'Istanbul University', 'ror': 'https://ror.org/03a5qrr21', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I67581229']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Mutlu K���k', 'raw_affiliation_strings': ['Department of Physiology Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology Istanbul Faculty of Medicine, University of Istanbul, Çapa, Istanbul, Turkey', 'institution_ids': ['https://openalex.org/I67581229']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4640, 'currency': 'USD', 'value_usd': 4640, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.257, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 13, 'citation_normalized_percentile': {'value': 0.631223, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '62', 'issue': '5', 'first_page': '750', 'last_page': '753'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10724', 'display_name': 'Molecular Mechanisms of Aquaporins in Physiology and Disease', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10724', 'display_name': 'Molecular Mechanisms of Aquaporins in Physiology and Disease', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11967', 'display_name': 'Diagnosis and Management of Hyponatremia', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10077', 'display_name': 'Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hyponatremia', 'display_name': 'Hyponatremia', 'score': 0.466682}], 'concepts': [{'id': 'https://openalex.org/C2778402981', 'wikidata': 'https://www.wikidata.org/wiki/Q221694', 'display_name': 'Blood–brain barrier', 'level': 3, 'score': 0.6472697}, {'id': 'https://openalex.org/C23265538', 'wikidata': 'https://www.wikidata.org/wiki/Q300033', 'display_name': 'ATPase', 'level': 3, 'score': 0.5811109}, {'id': 'https://openalex.org/C120882062', 'wikidata': 'https://www.wikidata.org/wiki/Q28352', 'display_name': 'Permeability (electromagnetism)', 'level': 3, 'score': 0.5594917}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4526498}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.43437907}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.41482407}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.33968192}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.31193322}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.28784972}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.27403003}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.23887151}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.22551885}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001812', 'descriptor_name': 'Blood-Brain Barrier', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000254', 'descriptor_name': 'Sodium-Potassium-Exchanging ATPase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014869', 'descriptor_name': 'Water Intoxication', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000208', 'descriptor_name': 'Acute Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009994', 'descriptor_name': 'Osmolar Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010539', 'descriptor_name': 'Permeability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012737', 'descriptor_name': 'Sex Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000254', 'descriptor_name': 'Sodium-Potassium-Exchanging ATPase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014869', 'descriptor_name': 'Water Intoxication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014869', 'descriptor_name': 'Water Intoxication', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1097-4547(20001201)62:5<750::aid-jnr15>3.0.co;2-8', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S76417895', 'display_name': 'Journal of Neuroscience Research', 'issn_l': '0360-4012', 'issn': ['0360-4012', '1097-4547'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11104514', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'score': 0.57, 'display_name': 'Clean water and sanitation'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W104569422', 'https://openalex.org/W12206678', 'https://openalex.org/W1570910952', 'https://openalex.org/W1603776666', 'https://openalex.org/W1775749144', 'https://openalex.org/W1903824959', 'https://openalex.org/W1969862544', 'https://openalex.org/W1979291973', 'https://openalex.org/W1981904558', 'https://openalex.org/W2001715624', 'https://openalex.org/W2008899369', 'https://openalex.org/W2009243881', 'https://openalex.org/W2012426220', 'https://openalex.org/W2012794847', 'https://openalex.org/W2017216675', 'https://openalex.org/W2036965165', 'https://openalex.org/W2049405167', 'https://openalex.org/W2049846371', 'https://openalex.org/W2050285850', 'https://openalex.org/W2050971162', 'https://openalex.org/W2054562744', 'https://openalex.org/W2058828682', 'https://openalex.org/W2059019924', 'https://openalex.org/W2063920673', 'https://openalex.org/W2068734705', 'https://openalex.org/W2073330884', 'https://openalex.org/W2083657430', 'https://openalex.org/W2214771906', 'https://openalex.org/W2406414528', 'https://openalex.org/W609865038'], 'related_works': ['https://openalex.org/W4249176446', 'https://openalex.org/W2748952813', 'https://openalex.org/W2132898409', 'https://openalex.org/W2086651592', 'https://openalex.org/W2069416673', 'https://openalex.org/W2037631372', 'https://openalex.org/W1991560548', 'https://openalex.org/W1984079239', 'https://openalex.org/W1979139803', 'https://openalex.org/W1966504330'], 'abstract_inverted_index': {'Journal': [0], 'of': [1, 32, 36, 39, 57, 61, 64, 70, 73, 88, 92, 95, 110, 114, 117, 133, 137, 140, 158, 162, 165, 171, 174, 189, 193, 196, 211, 215, 218, 255, 265, 278, 289, 311, 314, 327, 344, 352, 435], 'Neuroscience': [2], 'ResearchVolume': [3], '62,': [4], 'Issue': [5], '5': [6], 'p.': [7], '750-753': [8, 483], 'Research': [9], 'Article': [10], 'Sex-dependent': [11], 'changes': [12], 'in': [13, 21, 320, 341, 384, 401, 415, 420, 423, 454, 462], 'blood-brain': [14], 'barrier': [15, 330], 'permeability': [16, 332, 383, 461], 'and': [17, 253, 257, 269, 276, 295, 358, 363, 372, 378, 406, 458], 'brain': [18, 329], 'NA+,K+ATPase': [19], 'activity': [20, 340, 422, 457], 'rats': [22, 345, 353, 365, 380, 386, 408, 429, 464], 'following': [23, 392, 465], 'acute': [24, 347, 393], 'water': [25, 334, 348, 375, 394, 403, 426, 466], 'intoxication': [26], 'Baria': [27, 29, 128, 130], 'Öztaş,': [28, 129], 'Öztaş': [30, 131], 'Department': [31, 56, 72, 87, 109, 132, 157, 173, 188, 210], 'Physiology,': [33, 111, 134, 212], 'Istanbul': [34, 59, 90, 112, 135, 160, 191, 213], 'Faculty': [35, 60, 69, 91, 113, 136, 161, 170, 192, 214], 'Medicine,': [37, 62, 71, 93, 115, 138, 163, 172, 194, 216], 'University': [38, 63, 94, 116, 139, 164, 195, 217], 'Istanbul,': [40, 42, 65, 67, 76, 96, 98, 118, 120, 141, 143, 166, 168, 177, 197, 199, 219, 221], 'Çapa,': [41, 66, 97, 119, 142, 167, 198, 220], 'TurkeySearch': [43, 77, 99, 121, 144, 178, 200, 222], 'for': [44, 78, 100, 122, 145, 179, 201, 223, 449], 'more': [45, 79, 101, 123, 146, 180, 202, 224, 431], 'papers': [46, 80, 102, 124, 147, 181, 203, 225], 'by': [47, 81, 103, 125, 148, 182, 204, 226], 'this': [48, 82, 104, 126, 149, 183, 205, 227, 290], 'authorHikmet': [49, 150], 'Koçak,': [50, 151], 'Corresponding': [51, 152], 'Author': [52, 153], 'Hikmet': [53, 154], 'Koçak': [54, 155], '[email protected]': [55, 156], 'Biochemistry,': [58, 74, 89, 159, 175, 190], 'TurkeyIstanbul': [68, 169], 'Çapa': [75, 176], 'authorPernur': [83, 184], 'Öner,': [84, 185], 'Pernur': [85, 186], 'Öner': [86, 187], 'authorMutlu': [105, 206], 'Küçük,': [106, 207], 'Mutlu': [107, 208], 'Küçük': [108, 209], 'author': [127, 228], 'First': [229], 'published:': [230], '29': [231], 'November': [232], '2000': [233, 474], 'https://doi.org/10.1002/1097-4547(20001201)62:5<750::AID-JNR15>3.0.CO;2-8Citations:': [234], '12AboutPDF': [235], 'ToolsRequest': [236], 'permissionExport': [237], 'citationAdd': [238], 'to': [239, 261, 284, 317, 333, 389], 'favoritesTrack': [240], 'citation': [241], 'ShareShare': [242], 'Give': [243], 'accessShare': [244, 247], 'full': [245], 'text': [246], 'full-text': [248, 263, 287], 'accessPlease': [249], 'review': [250], 'our': [251], 'Terms': [252, 275], 'Conditions': [254, 277], 'Use': [256], 'check': [258], 'box': [259], 'below': [260, 283], 'share': [262, 285], 'version': [264, 288], 'article.I': [266], 'have': [267], 'read': [268], 'accept': [270], 'the': [271, 281, 308, 312, 325, 337, 450], 'Wiley': [272], 'Online': [273], 'Library': [274], 'UseShareable': [279], 'LinkUse': [280], 'link': [282], 'a': [286, 301], 'article': [291], 'with': [292, 336, 367], 'your': [293], 'friends': [294], 'colleagues.': [296], 'Learn': [297], 'more.Copy': [298], 'URL': [299], 'Share': [300], 'linkShare': [302], 'onFacebookTwitterLinked': [303], 'InRedditWechat': [304], 'Abstract': [305], 'To': [306], 'understand': [307], 'increased': [309, 391, 459], 'susceptibility': [310], 'development': [313], 'serious': [315], 'complications': [316], 'hypoosmotic': [318], 'hyponatremia': [319], 'young': [321], 'females,': [322], 'we': [323], 'examined': [324], 'resistance': [326], 'blood': [328], '(BBB)': [331], 'along': [335], 'synaptosomal': [338, 398, 455], 'Na+,K+ATPase': [339, 399, 456], 'both': [342, 402], 'sexes': [343], 'during': [346], 'intoxication.': [349, 395, 467], 'Four': [350], 'groups': [351], 'were': [354, 360, 374, 409], 'used:': [355], 'Group': [356, 370], 'I': [357], 'II': [359], 'normal': [361], 'female': [362, 377, 385, 407, 428, 443, 463], 'male': [364, 379, 405, 437], 'injected': [366], 'only': [368], 'Evans-blue.': [369], 'III': [371], 'IV': [373], 'intoxicated': [376, 404, 427], 'respectively.': [381], 'BBB': [382, 460], 'was': [387, 430], 'found': [388, 410], 'be': [390, 447], 'In': [396], 'contrast,': [397], 'activities': [400], 'significantly': [411], 'lower': [412], 'than': [413, 433], 'those': [414, 434], 'control': [416], 'rats.': [417, 438], 'But': [418], 'inhibition': [419], 'enzyme': [421], 'synaptosomes': [424], 'from': [425], 'pronounced': [432], 'corresponding': [436], 'Our': [439], 'results': [440], 'concuded': [441], 'that': [442], 'sex': [444], 'steroids': [445], 'may': [446], 'responsible': [448], 'highly': [451], 'significant': [452], 'decrease': [453], 'J.': [468], 'Neurosci.': [469], 'Res.': [470], '62:750–753,': [471], '2000.': [472], '©': [473], 'Wiley-Liss,': [475], 'Inc.': [476], 'Citing': [477], 'Literature': [478], 'Volume62,': [479], 'Issue51': [480], 'December': [481], '2000Pages': [482], 'RelatedInformation': [484]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2016419664', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-08-15T05:47:17.575859', 'created_date': '2016-06-24'}