Title: Synthesis of the active stilbenoids by photooxidation reaction of trans‐ϵ‐viniferin
Abstract:Abstract Two new stilbenoids, cis ‐ϵ‐viniferin (3) and 2b, 14b‐dehydro‐bisresveratrol (4) were synthesized by photooxidation reaction of trans ‐ϵ‐viniferin (2) prepared from tram‐resveratrol (1). Pent...Abstract Two new stilbenoids, cis ‐ϵ‐viniferin (3) and 2b, 14b‐dehydro‐bisresveratrol (4) were synthesized by photooxidation reaction of trans ‐ϵ‐viniferin (2) prepared from tram‐resveratrol (1). Pentamethoxyl trans ‐ϵ‐viniferin (5) and pentamethoxyl cis ‐ϵ‐viniferin (6) were also obtained by methylation of trans ‐ϵ‐viniferin (2) with (MeO) 2 SO 2 . Their structures were elucidated on the basis of spectral evidence. Compounds 3 and 4 showed potent inhibition of TNF‐α at concentrations of 10 − ‐ 5 mol.L −1 with inhibitory ratios of 51.43% and 36.64%. respectively.Read More
Publication Year: 2004
Publication Date: 2004-11-01
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 30
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