Publication Information

{'id': 'https://openalex.org/W2015491575', 'doi': 'https://doi.org/10.5664/jcsm.2682', 'title': 'CPAP and Cognition in OSA (APPLES)', 'display_name': 'CPAP and Cognition in OSA (APPLES)', 'publication_year': 2013, 'publication_date': '2013-05-14', 'ids': {'openalex': 'https://openalex.org/W2015491575', 'doi': 'https://doi.org/10.5664/jcsm.2682', 'mag': '2015491575', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23674945', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3629328'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5664/jcsm.2682', 'pdf_url': 'http://jcsm.aasm.org/Articles/jcsm.9.5.515.pdf', 'source': {'id': 'https://openalex.org/S48878068', 'display_name': 'Journal of Clinical Sleep Medicine', 'issn_l': '1550-9389', 'issn': ['1550-9389', '1550-9397'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315582', 'host_organization_name': 'American Academy of Sleep Medicine', 'host_organization_lineage': ['https://openalex.org/P4310315582'], 'host_organization_lineage_names': ['American Academy of Sleep Medicine'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://jcsm.aasm.org/Articles/jcsm.9.5.515.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5062700391', 'display_name': 'David J. Berlowitz', 'orcid': 'https://orcid.org/0000-0003-2543-8722'}, 'institutions': [{'id': 'https://openalex.org/I4210098456', 'display_name': 'Institute for Breathing and Sleep', 'ror': 'https://ror.org/00ymae584', 'country_code': 'AU', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210098456']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'David J. Berlowitz', 'raw_affiliation_strings': ['Institute for Breathing and Sleep, Melbourne, Australia.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Breathing and Sleep, Melbourne, Australia.', 'institution_ids': ['https://openalex.org/I4210098456']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5043955232', 'display_name': 'Shirin Shafazand', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145608581', 'display_name': 'University of Miami', 'ror': 'https://ror.org/02dgjyy92', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145608581']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Shirin Shafazand', 'raw_affiliation_strings': ['University of Miami,Miami, Florida'], 'affiliations': [{'raw_affiliation_string': 'University of Miami,Miami, Florida', 'institution_ids': ['https://openalex.org/I145608581']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': False, 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.758118, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '09', 'issue': '05', 'first_page': '515', 'last_page': '516'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10234', 'display_name': 'Obstructive Sleep Apnea Research', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10234', 'display_name': 'Obstructive Sleep Apnea Research', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/sleep', 'display_name': 'Sleep', 'score': 0.42059124}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.69755924}, {'id': 'https://openalex.org/C169900460', 'wikidata': 'https://www.wikidata.org/wiki/Q2200417', 'display_name': 'Cognition', 'level': 2, 'score': 0.6674331}, {'id': 'https://openalex.org/C2776006263', 'wikidata': 'https://www.wikidata.org/wiki/Q16606552', 'display_name': 'Obstructive sleep apnea', 'level': 2, 'score': 0.4870258}, {'id': 'https://openalex.org/C2775841894', 'wikidata': 'https://www.wikidata.org/wiki/Q4683692', 'display_name': 'Sleep (system call)', 'level': 2, 'score': 0.42059124}, {'id': 'https://openalex.org/C2778205975', 'wikidata': 'https://www.wikidata.org/wiki/Q1754874', 'display_name': 'Polysomnography', 'level': 3, 'score': 0.41583192}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.27038935}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.16168353}, {'id': 'https://openalex.org/C522805319', 'wikidata': 'https://www.wikidata.org/wiki/Q179965', 'display_name': 'Electroencephalography', 'level': 2, 'score': 0.10503572}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003071', 'descriptor_name': 'Cognition', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D045422', 'descriptor_name': 'Continuous Positive Airway Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D056344', 'descriptor_name': 'Executive Function', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D020181', 'descriptor_name': 'Sleep Apnea, Obstructive', 'qualifier_ui': 'Q000523', 'qualifier_name': 'psychology', 'is_major_topic': True}, {'descriptor_ui': 'D020181', 'descriptor_name': 'Sleep Apnea, Obstructive', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D003071', 'descriptor_name': 'Cognition', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056344', 'descriptor_name': 'Executive Function', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020181', 'descriptor_name': 'Sleep Apnea, Obstructive', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.5664/jcsm.2682', 'pdf_url': 'http://jcsm.aasm.org/Articles/jcsm.9.5.515.pdf', 'source': {'id': 'https://openalex.org/S48878068', 'display_name': 'Journal of Clinical Sleep Medicine', 'issn_l': '1550-9389', 'issn': ['1550-9389', '1550-9397'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315582', 'host_organization_name': 'American Academy of Sleep Medicine', 'host_organization_lineage': ['https://openalex.org/P4310315582'], 'host_organization_lineage_names': ['American Academy of Sleep Medicine'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3629328', 'pdf_url': 'https://europepmc.org/articles/pmc3629328?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629328', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23674945', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5664/jcsm.2682', 'pdf_url': 'http://jcsm.aasm.org/Articles/jcsm.9.5.515.pdf', 'source': {'id': 'https://openalex.org/S48878068', 'display_name': 'Journal of Clinical Sleep Medicine', 'issn_l': '1550-9389', 'issn': ['1550-9389', '1550-9397'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315582', 'host_organization_name': 'American Academy of Sleep Medicine', 'host_organization_lineage': ['https://openalex.org/P4310315582'], 'host_organization_lineage_names': ['American Academy of Sleep Medicine'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4390146185', 'https://openalex.org/W4389568370', 'https://openalex.org/W4200607786', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W3004206652', 'https://openalex.org/W2748952813', 'https://openalex.org/W2186303850', 'https://openalex.org/W2016370421', 'https://openalex.org/W1995515455'], 'abstract_inverted_index': {'Free': [0], 'AccessCPAPCPAP': [1], 'and': [2, 23, 48, 137, 154, 170, 186, 304, 361, 373, 375, 386, 396, 405, 439, 469, 542, 687, 692, 698, 711, 714, 748, 815, 875, 902, 942, 962, 994, 1012, 1021, 1024, 1099, 1124, 1143, 1235, 1260, 1281, 1313, 1321, 1340, 1358, 1365, 1397], 'Cognition': [3], 'in': [4, 101, 168, 181, 203, 239, 294, 463, 502, 506, 519, 599, 614, 753, 802, 809, 824, 858, 869, 886, 889, 900, 955, 958, 1015, 1039, 1092, 1128, 1145, 1168, 1192, 1212], 'OSA': [5, 211, 231, 303, 531, 560, 874, 1011, 1146], '(APPLES)': [6, 742], 'David': [7, 16], 'J.': [8, 17], 'Berlowitz,': [9, 18], 'Ph.D.,': [10, 721], 'Shirin': [11, 28, 36], 'Shafazand,': [12, 29, 37], 'M.D.,': [13, 30, 38, 720], 'M.S.,': [14, 31, 39], 'F.A.A.S.M.': [15, 32], 'Ph.D.': [19], 'Institute': [20], 'for': [21, 258, 299, 418, 441, 487, 554, 587, 605, 734, 786, 946, 985, 1032, 1209, 1353], 'Breathing': [22], 'Sleep,': [24], 'Melbourne,': [25], 'Australia': [26], ',': [27, 1242], 'Address': [33], 'correspondence': [34], 'to:': [35], 'University': [40, 65, 697], 'of': [41, 44, 66, 87, 148, 261, 301, 322, 329, 402, 425, 452, 460, 476, 530, 607, 640, 664, 684, 727, 765, 790, 792, 798, 812, 898, 966, 969, 1035, 1110, 1120, 1137, 1163, 1215, 1285, 1307, 1325, 1348, 1362, 1433], 'Miami,': [42, 55], 'Division': [43], 'Pulmonary,': [45], 'Critical': [46], 'Care': [47, 1177], 'Sleep': [49, 685, 689, 736, 1150, 1238, 1287, 1434], 'Medicine,': [50, 1288], 'PO': [51], 'Box': [52], '016960': [53], '(D60),': [54], 'FL,': [56], '33101,': [57], 'United': [58, 183], 'States(305)': [59], '243-7838': [60], 'E-mail': [61], 'Address:': [62], '[email': [63, 724], 'protected]': [64], 'Miami,Miami,': [67], 'Florida': [68], 'Published': [69, 1425], 'Online:May': [70], '15,': [71, 1416, 1427], '2013https://doi.org/10.5664/jcsm.2682Cited': [72], 'by:4SectionsPDF': [73], 'ShareShare': [74], 'onFacebookTwitterLinkedInRedditEmail': [75], 'ToolsAdd': [76], 'to': [77, 128, 131, 142, 334, 447, 455, 496, 574, 592, 624, 695, 703, 772, 865, 910, 916, 979, 1029, 1050, 1068, 1106, 1117, 1207, 1255], 'favoritesDownload': [78], 'CitationsTrack': [79], 'Citations': [80], 'AboutARTICLE': [81], 'SUMMARYQuestion:': [82], 'What': [83], 'is': [84, 479, 743, 757, 781, 828, 981, 1019], 'the': [85, 132, 146, 155, 163, 171, 182, 240, 262, 323, 406, 419, 456, 467, 488, 517, 520, 538, 557, 588, 608, 615, 631, 638, 681, 688, 700, 709, 754, 788, 793, 796, 803, 810, 825, 848, 853, 856, 884, 896, 920, 926, 930, 944, 952, 959, 963, 970, 976, 1001, 1004, 1008, 1025, 1033, 1036, 1040, 1047, 1051, 1055, 1075, 1084, 1108, 1118, 1248, 1299, 1305, 1344], 'effect': [86, 450, 474, 726, 1080], 'continuous': [88, 1164, 1366], 'positive': [89, 1165, 1367], 'airway': [90, 1166, 1368], 'pressure': [91, 1167], '(CPAP)': [92, 732], 'therapy': [93, 97, 648, 893], 'versus': [94], 'Sham': [95, 470, 804, 960, 984], 'CPAP': [96, 205, 234, 244, 336, 471, 582, 617, 647, 662, 784, 1126, 1142], 'on': [98, 414, 660, 739, 1262], 'neurocognitive': [99, 273, 283, 347, 395, 546, 570, 594, 652, 740, 779, 1071, 1314], 'function': [100, 284, 388, 741, 780, 817], 'patients': [102, 292], 'with': [103, 145, 210, 212, 233, 242, 320, 556, 645, 658, 774, 871, 892, 938, 948], 'obstructive': [104, 1170, 1300], 'sleep': [105, 179, 266, 297, 876, 1171, 1301, 1355], 'apnea': [106, 213, 1302], '(OSA)?Design:': [107], 'Multi-center,': [108], 'randomized,': [109], 'double': [110], 'blinded,': [111], 'sham': [112, 195, 339, 507, 581, 661], 'controlled': [113, 1161, 1346], 'trial;': [114], 'ClinicalTrials.gov': [115], 'Identifier:': [116], 'NCT00051363.Allocation:': [117], 'The': [118, 224, 342, 390, 672, 762, 1195], 'Data': [119], 'Coordinating': [120], 'Center': [121], 'used': [122], 'a': [123, 295, 327, 351, 481, 620, 759, 799, 832, 837, 1064, 1093], 'computerized': [124], 'permuted': [125], 'block': [126], 'design': [127], 'randomize': [129], 'participants': [130, 190, 428, 870, 997], '2': [133, 397, 589, 807, 915], 'study': [134, 416, 437, 552, 931], 'arms.Blinding:': [135], 'Participants': [136, 331], 'most': [138, 558], 'personnel': [139], 'were': [140, 208, 222, 288, 332, 345, 393, 572, 601, 676, 894, 907], 'blinded': [141], 'treatment': [143, 232, 337, 733, 785, 949], 'assignments,': [144], 'exception': [147], 'site': [149], 'coordinators,': [150], 'polysomnography': [151], '(PSG)': [152], 'technologists,': [153], 'database': [156], 'administrator/data': [157], 'manager.Follow-up': [158], 'period:': [159], '6': [160, 524, 566, 655, 917], 'month': [161, 174], 'follow-up;': [162], 'first': [164], 'participant': [165], 'was': [166, 175, 311, 315, 412, 445, 511, 667, 771, 836, 922, 933, 1082], 'enrolled': [167], '11/2003': [169], 'final': [172], 'completion': [173], '8/2008.Setting:': [176], '5': [177], 'clinical': [178, 1193], 'centers': [180], 'States': [184], '(academic': [185], 'private': [187], 'settings).Subjects:': [188], '1,098': [189], '(556': [191], 'active': [192, 204, 503, 579, 616], 'CPAP,': [193, 196], '542': [194], '35%': [197], 'women,': [198], 'mean': [199], 'age': [200], '52': [201], 'years': [202], 'group)': [206], 'who': [207], 'diagnosed': [209], 'hypopnea': [214], 'index': [215], '(AHI)': [216], '≥': [217, 477, 584], '10': [218], 'events': [219], 'per': [220], 'hour': [221], 'randomized.': [223], 'primary': [225, 343, 491, 521, 539, 569, 609, 763, 794], 'exclusion': [226], 'criteria': [227], 'were:': [228], '1)': [229, 354], 'prior': [230, 591], 'or': [235, 277, 338, 534, 580, 635], 'surgery;': [236], '2)': [237, 364], 'anyone': [238], 'household': [241], 'current/past': [243], 'use;': [245], '3)': [246, 376], 'sleepiness-related': [247], 'automobile': [248], 'accident': [249], 'within': [250], 'past': [251], 'year;': [252], '4)': [253], 'oxygen': [254, 535], 'saturation': [255, 536], '<': [256], '75%': [257], '>': [259], '10%': [260], 'diagnostic': [263], 'PSG': [264], 'total': [265, 427], 'time;': [267], 'and/or': [268, 285], '5)': [269], 'conditions': [270], '(including': [271], 'known': [272], 'impairment),': [274], 'disorders,': [275], 'medications,': [276], 'substances': [278], 'that': [279, 317, 561, 834, 883, 904, 1007, 1060, 1081], 'could': [280], 'potentially': [281], 'affect': [282], 'alertness.': [286], 'Subjects': [287], 'recruited': [289], 'primarily': [290], 'from': [291, 305, 680, 751, 914, 1054, 1343], 'scheduled': [293], 'regular': [296], 'clinic': [298], 'evaluation': [300], 'possible': [302], 'local': [306], 'advertising.': [307], 'Although': [308], 'recruitment': [309], 'source': [310], 'not': [312, 563, 650], 'tracked,': [313], 'it': [314, 835], 'estimated': [316, 446], 'initial': [318], 'contact': [319], '~70%': [321], 'subjects': [324], 'occurred': [325], 'as': [326, 847, 978], 'result': [328], 'advertisement.Intervention:': [330], 'randomized': [333, 1160], 'receive': [335], 'CPAP.': [340], 'Outcomes:': [341], 'outcomes': [344, 392, 522, 610, 859], '3': [346, 442], 'variables,': [348], 'each': [349, 593], 'representing': [350], 'neuro-cognitive': [352], 'domain:': [353], 'Pathfinder': [355, 420], 'Number': [356, 421], 'Test-Total': [357], 'Time': [358], 'assesses': [359, 370, 383], 'attention': [360], 'psychomotor': [362], 'function;': [363], 'Buschke': [365], 'Selective': [366], 'Reminding': [367], 'Test-Sum': [368], 'Recall': [369], 'verbal': [371], 'learning': [372], 'memory;': [374], 'Sustained': [377], 'Working': [378], 'Memory': [379], 'Test-Overall': [380], 'Mid-Day': [381], 'Index': [382], 'an': [384, 449, 744, 982, 1062], 'executive': [385, 816], 'frontal-lobe': [387], '(E/F).': [389], 'secondary': [391, 544], '7': [394], 'sleepiness': [398, 887, 921], 'measures': [399, 529, 653], '(the': [400], 'maintenance': [401, 639], 'wakefulness': [403, 641], 'test': [404], 'Epworth': [407, 632], 'Sleepiness': [408, 633], 'Scale).The': [409], 'sample': [410, 932], 'size': [411, 451, 475], 'based': [413], 'pilot': [415, 674], 'results': [417, 1037, 1342], 'Test.': [422], 'A': [423, 1320], 'target': [424], '1,100': [426], '(assuming': [429], '90%': [430], 'power,': [431, 777], '2-sided': [432], 'α': [433], '=': [434], '0.05,': [435], '20%': [436], 'dropout,': [438], 'allowing': [440], 'interim': [443], 'analyses)': [444], 'achieve': [448], '0.2,': [453], 'translating': [454], 'clinically': [457, 482], 'significant': [458, 483, 514], 'difference': [459, 486, 515, 857], '26': [461], 'msec': [462], 'reaction': [464], 'time': [465], 'between': [466, 484, 516, 551, 603, 1010], 'Active': [468, 826, 861], 'groups.': [472], 'An': [473], '0.2': [478], 'also': [480, 974, 1028], 'group': [485, 618], 'other': [489], 'two': [490], 'outcome': [492], 'measures.Patient': [493], 'Follow-Up:': [494], 'intention': [495], 'treat': [497], 'analysis,': [498, 855], '79%': [499], 'completed': [500], 'follow-up': [501], 'arm,': [504], '74%': [505], 'arm.Main': [508], 'Results:': [509], 'There': [510, 830], 'no': [512, 597, 1134], 'statistically': [513], 'groups': [518], 'at': [523, 565, 611, 654, 806, 862, 878, 1304], 'months.': [525, 567], 'When': [526, 568], 'stratified': [527], 'by': [528, 630, 637, 669, 678, 699, 783, 996, 1205], 'severity': [532], '(AHI': [533], 'parameters),': [537], 'E/F': [540, 545, 901], 'variable': [541, 547], 'one': [543], 'revealed': [548], 'transient': [549], 'differences': [550, 598], 'arms': [553, 604], 'those': [555, 659, 890, 937], 'severe': [559, 873, 1017], 'did': [562, 649], 'persist': [564], 'analyses': [571], 'restricted': [573], 'CPAP-adherent': [575], 'individuals': [576], '(mean': [577], 'nightly': [578], 'adherence': [583, 956], '4': [585], 'h': [586], 'months': [590, 656, 918], 'testing': [595], 'visit),': [596], 'means': [600], 'detected': [602], 'any': [606, 612, 821], 'visit.Participants': [613], 'had': [619, 1061], 'significantly': [621], 'greater': [622, 953], 'ability': [623], 'remain': [625], 'awake': [626], 'whether': [627, 778], 'measured': [628], 'subjectively': [629], 'Scale': [634], 'objectively': [636], 'test.Conclusion:': [642], 'In': [643], 'adults': [644], 'OSA,': [646], 'improve': [651], 'compared': [657], 'therapy.Sources': [663], 'Funding:': [665], 'APPLES': [666, 673, 1063], 'funded': [668], 'NHLBI': [670], '(HL68080).': [671], 'studies': [675, 1113], 'supported': [677], 'grants': [679], 'American': [682, 1431], 'Academy': [683, 1432], 'Medicine': [686, 690, 1239], 'Education': [691], 'Research': [693], 'Foundation': [694], 'Stanford': [696], 'NINDS': [701], '(N44NS002394)': [702], 'SAM': [704], 'Technology.': [705], 'Respironics®,': [706], 'Inc.': [707], 'supplied': [708], 'active-': [710], 'sham-CPAP': [712], 'devices': [713, 1364], 'equipment.For': [715], 'Correspondence:': [716], 'Clete': [717], 'A.': [718], 'Kushida,': [719], 'F.A.A.S.M.;': [722], 'Email:': [723], 'protected]eduCOMMENTARYThe': [725], 'Continuous': [728, 1216], 'Positive': [729, 1217], 'Airway': [730, 1218], 'Pressure': [731], 'Obstructive': [735, 1354], 'Apnea': [737], '(OSA)': [738], 'NIH-funded,': [745], 'impeccably': [746], 'designed': [747], 'executed': [749], 'RCT': [750], 'experts': [752], 'field': [755], 'which': [756], 'essentially': [758], 'negative': [760, 1078], 'study.': [761, 1056], 'aim': [764], 'this': [766, 843], 'five': [767], 'year,': [768], 'multi-site': [769], 'investigation': [770], 'determine,': [773], 'sufficient': [775], 'statistical': [776, 840, 967], 'improved': [782], 'OSA.From': [787], 'point': [789], 'view': [791], 'endpoints,': [795], 'finding': [797], 'small': [800], 'deterioration': [801, 899], 'condition': [805], 'months,': [808], 'domain': [811], 'frontal': [813], 'lobe': [814], '(E/F),': [818], 'rather': [819, 1073], 'than': [820, 1074], 'large': [822], 'improvement': [823, 947], 'arm': [827], 'intriguing.': [829], 'remains': [831], 'chance': [833], 'type': [838], '1': [839], 'error.': [841], 'However': [842], 'seems': [844], 'unlikely': [845], 'because': [846], 'authors': [849, 927, 1023, 1131], 'delved': [850], 'deeper': [851], 'into': [852], 'efficacy': [854, 971], 'favoring': [860], '2-months': [863], 'appeared': [864], 'strengthen': [866], 'overall,': [867], 'particularly': [868, 1014], 'more': [872, 939, 1016], 'dysfunction': [877], 'baseline.': [879], 'One': [880], 'might': [881], 'speculate': [882], 'improvements': [885], 'seen': [888], 'adherent': [891], 'mediating': [895], 'lack': [897], 'furthermore': [903], 'these': [905, 1100], 'benefits': [906], 'less': [908], 'able': [909], 'be': [911, 1030], 'built': [912], 'upon': [913], '(as': [919], 'already': [923], '"cured").': [924], 'As': [925], 'note,': [928], 'perhaps': [929], 'fundamentally': [934], 'biased': [935], 'towards': [936], 'cognitive': [940], 'reserve': [941], 'thus': [943], 'potential': [945], 'reduced.': [950], 'Additionally,': [951], 'reduction': [954], 'observed': [957], 'group,': [961], 'subsequent': [964], 'loss': [965], 'power': [968], 'analyses,': [972], 'may': [973], 'reignite': [975], 'debate': [977], 'what': [980], 'appropriate': [983], 'CPAP;': [986], 'sugar': [987], 'pills': [988], 'are': [989, 1027, 1114], 'well': [990], 'tolerated': [991], '(93%': [992], 'adherence)': [993], 'preferred': [995], 'over': [998], 'CPAP.1': [999], 'Regardless,': [1000], 'data': [1002, 1044, 1102], 'support': [1003], "authors'": [1005], 'conclusion': [1006], 'relationship': [1009], 'neurocognition,': [1013], 'disease,': [1018], 'real': [1020], 'complex.The': [1022], 'journal': [1026, 1098], 'commended': [1031], 'publication': [1034, 1244, 1295, 1335], 'contained': [1038], 'Appendices.': [1041], 'These': [1042], 'comprehensive': [1043], 'substantially': [1045, 1069], 'increase': [1046, 1070], 'information': [1048], 'available': [1049], 'scientific': [1052], 'community': [1053], 'I': [1057], 'would': [1058, 1086, 1103], 'attest': [1059], 'day': [1065], 'been': [1066, 1088], 'found': [1067], 'function,': [1072], 'equivocal,': [1076], 'arguably': [1077], 'overall': [1079], 'demonstrated,': [1083], 'paper': [1085], 'have': [1087, 1104, 1132], 'far': [1089], 'shorter,': [1090], 'published': [1091], 'higher': [1094], 'impact': [1095], 'general': [1096], 'medical': [1097], 'valuable': [1101], 'struggled': [1105], 'see': [1107], 'light': [1109], 'day.2': [1111], 'Negative': [1112], 'vital': [1115], 'contributors': [1116], 'body': [1119], 'knowledge': [1121], 'about': [1122], 'how': [1123], 'why': [1125], 'works': [1127], 'OSA.DISCLOSURE': [1129], 'STATEMENTThe': [1130], 'indicated': [1133], 'financial': [1135], 'conflicts': [1136], 'interest.CITATIONBerlowitz': [1138], 'DJ;': [1139], 'Shafazand': [1140], 'S.': [1141], 'cognition': [1144], '(APPLES).': [1147], 'J': [1148, 1174, 1396], 'Clin': [1149], 'Med': [1151], '2013;9(5):515-516.REFERENCES1': [1152], 'Barnes': [1153], 'M,': [1154, 1264, 1316, 1372, 1376, 1382, 1386, 1388, 1394], 'Houston': [1155], 'D,': [1156, 1222], 'Worsnop': [1157], 'CJet': [1158], 'al.A': [1159], 'trial': [1162], 'mild': [1169], 'apnea.': [1172], 'Am': [1173], 'Respir': [1175], 'Crit': [1176], 'Med;': [1178], '2002;165:773-80,': [1179], '11897643.': [1180], 'CrossrefGoogle': [1181, 1198], 'Scholar2': [1182], 'Easterbrook': [1183], 'PJ,': [1184], 'Gopalan': [1185], 'R,': [1186, 1380], 'Berlin': [1187], 'JA,': [1188], 'Matthews': [1189], 'DRPublication': [1190], 'bias': [1191], 'research.': [1194], 'Lancet;': [1196], '1991;337:867-72.': [1197], 'Scholar': [1199], 'Previous': [1200], 'article': [1201, 1203], 'Next': [1202, 1208], 'FiguresReferencesRelatedDetailsCited': [1204], 'Where': [1206], 'Optimizing': [1210], 'Adherence': [1211], 'Large-Scale': [1213], 'Trials': [1214], 'Pressure?Sawyer': [1219], 'A,': [1220, 1226, 1228, 1374], 'Wallace': [1221], 'Buenaver': [1223], 'L,': [1224, 1266, 1370], 'Watach': [1225], 'Blase': [1227], 'Saconi': [1229], 'B,': [1230], 'Patel': [1231], 'S,': [1232, 1270, 1276, 1318], 'Kuna': [1233], 'S': [1234, 1323], 'Punjabi': [1236], 'N': [1237], 'Clinics,': [1240], '10.1016/j.jsmc.2020.10.007,': [1241], 'Online': [1243, 1294, 1334], 'date:': [1245, 1296, 1336], '1-Dec-2020.': [1246], 'Integrating': [1247], 'Divided': [1249], 'Nasal': [1250, 1257], 'Cannula': [1251], 'Into': [1252], 'Routine': [1253], 'Polysomnography': [1254], 'Assess': [1256], 'Cycle:': [1258], 'Feasibility': [1259], 'Effect': [1261], 'OutcomesScapuccin': [1263], 'Schneider': [1265], 'Rashid': [1267], 'N,': [1268, 1390], 'Zaghi': [1269], 'Rosa': [1271], 'T,': [1272], 'Tsou': [1273], 'Y,': [1274], 'Liu': [1275], 'Lazarini': [1277], 'P,': [1278], 'Capasso': [1279], 'R': [1280], 'Ruoff': [1282], 'C': [1283], 'Journal': [1284, 1324], 'Clinical': [1286, 1338], 'Vol.': [1289, 1329, 1404], '14,': [1290, 1330], 'No.': [1291, 1331, 1406], '04,': [1292], '(641-650),': [1293], '15-Apr-2018.': [1297], 'Withstanding': [1298], 'syndrome': [1303], 'expense': [1306], 'arousal': [1308], 'instability,': [1309], 'altered': [1310], 'cerebral': [1311], 'autoregulation': [1312], 'declineTorabi-Nami': [1315], 'Mehrabi': [1317], 'Borhani-Haghighi': [1319], 'Derman': [1322], 'Integrative': [1326], 'Neuroscience,': [1327], '10.1142/S0219635215500144,': [1328], '02,': [1332], '(169-193),': [1333], '1-Jun-2015.': [1337], 'effectiveness': [1339], 'cost-effectiveness': [1341], 'randomised': [1345], 'Trial': [1347], 'Oral': [1349], 'Mandibular': [1350], 'Advancement': [1351], 'Devices': [1352], 'apnoea–hypopnoea': [1356], '(TOMADO)': [1357], 'long-term': [1359], 'economic': [1360], 'analysis': [1361], 'oral': [1363], 'pressureSharples': [1369], 'Glover': [1371], 'Clutterbuck-James': [1373], 'Bennett': [1375], 'Jordan': [1377], 'J,': [1378], 'Chadwick': [1379], 'Pittman': [1381], 'East': [1383], 'C,': [1384], 'Cameron': [1385], 'Davies': [1387], 'Oscroft': [1389], 'Smith': [1391], 'I,': [1392], 'Morrell': [1393], 'Fox-Rushby': [1395], 'Quinnell': [1398], 'T': [1399], 'Health': [1400], 'Technology': [1401], 'Assessment,': [1402], '10.3310/hta18670,': [1403], '18,': [1405], '67,': [1407], '(1-296)': [1408], 'Volume': [1409], '09': [1410], '•': [1411, 1414], 'Issue': [1412], '05': [1413], 'May': [1415], '2013ISSN': [1417], '(print):': [1418], '1550-9389ISSN': [1419], '(online):': [1420], '1550-9397Frequency:': [1421], 'Monthly': [1422], 'Metrics': [1423], 'History': [1424], 'onlineMay': [1426], '2013': [1428, 1430], 'Information©': [1429], 'MedicinePDF': [1435], 'download': [1436]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2015491575', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2024-12-08T19:02:58.163577', 'created_date': '2016-06-24'}