Title: A New Steroidal Saponin from the Leaves of <i>Agave americana</i>
Abstract: A new bisdesmosidic spirostanol saponin, along with three known saponins, were isolated from Agave americana (Agavaceae). The structure of the new saponin was elucidated as (25R)-3 beta,6 alpha-dihydroxy-5 alpha-spirostan-12-one 3,6-di-O-beta-D-glucopyranoside. Among the isolated saponins, hecogenin tetraglycoside showed cytotoxic activity against HL-60 human promyelocytic leukemia cells with an IC50 value of 4.3 micrograms/mL.
Publication Year: 2000
Publication Date: 2000-12-31
Language: en
Type: letter
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 49
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