Publication Information

{'id': 'https://openalex.org/W2014535178', 'doi': 'https://doi.org/10.1097/wco.0b013e32833e5a5d', 'title': 'Steroids in neurooncology: actions, indications, side-effects', 'display_name': 'Steroids in neurooncology: actions, indications, side-effects', 'publication_year': 2010, 'publication_date': '2010-10-19', 'ids': {'openalex': 'https://openalex.org/W2014535178', 'doi': 'https://doi.org/10.1097/wco.0b013e32833e5a5d', 'mag': '2014535178', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20962642'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/wco.0b013e32833e5a5d', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S177945262', 'display_name': 'Current Opinion in Neurology', 'issn_l': '1350-7540', 'issn': ['1350-7540', '1473-6551'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5044206440', 'display_name': 'Patrick Roth', 'orcid': 'https://orcid.org/0000-0003-3897-214X'}, 'institutions': [{'id': 'https://openalex.org/I4210100468', 'display_name': 'University Hospital of Zurich', 'ror': 'https://ror.org/01462r250', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100468']}, {'id': 'https://openalex.org/I188703185', 'display_name': 'GTx (United States)', 'ror': 'https://ror.org/0400j3f74', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I188703185']}], 'countries': ['CH', 'US'], 'is_corresponding': True, 'raw_author_name': 'Patrick Roth', 'raw_affiliation_strings': ['Department of Neurology, University Hospital Zurich, Zurich, Switzerland', 'e-mail: [email\xa0protected]', 'fax: +41 44 255 4380', 'to Dr Patrick Roth, Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland Tel: +41 44 255 5511'], 'affiliations': [{'raw_affiliation_string': 'e-mail: [email\xa0protected]', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Neurology, University Hospital Zurich, Zurich, Switzerland', 'institution_ids': ['https://openalex.org/I4210100468']}, {'raw_affiliation_string': 'fax: +41 44 255 4380', 'institution_ids': ['https://openalex.org/I188703185']}, {'raw_affiliation_string': 'to Dr Patrick Roth, Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland Tel: +41 44 255 5511', 'institution_ids': ['https://openalex.org/I4210100468']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080482957', 'display_name': 'Wolfgang Wick', 'orcid': 'https://orcid.org/0000-0002-6171-634X'}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}, {'id': 'https://openalex.org/I4210111460', 'display_name': 'National Center for Tumor Diseases', 'ror': 'https://ror.org/01txwsw02', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210111460']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Wolfgang Wick', 'raw_affiliation_strings': ['Department of Neurooncology, Neurology Clinic and National Center for Tumor Disease, University of Heidelberg, Heidelberg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurooncology, Neurology Clinic and National Center for Tumor Disease, University of Heidelberg, Heidelberg, Germany', 'institution_ids': ['https://openalex.org/I223822909', 'https://openalex.org/I4210111460']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5017177249', 'display_name': 'Michael Weller', 'orcid': 'https://orcid.org/0000-0002-1748-174X'}, 'institutions': [{'id': 'https://openalex.org/I4210100468', 'display_name': 'University Hospital of Zurich', 'ror': 'https://ror.org/01462r250', 'country_code': 'CH', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100468']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Michael Weller', 'raw_affiliation_strings': ['Department of Neurology, University Hospital Zurich, Zurich, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, University Hospital Zurich, Zurich, Switzerland', 'institution_ids': ['https://openalex.org/I4210100468']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5044206440'], 'corresponding_institution_ids': ['https://openalex.org/I4210100468', 'https://openalex.org/I188703185'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.81, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 100, 'citation_normalized_percentile': {'value': 0.75838, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '23', 'issue': '6', 'first_page': '597', 'last_page': '602'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11600', 'display_name': 'Brain Metastases and Treatment', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12226', 'display_name': 'Neuroblastoma Research and Treatments', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/neurooncology', 'display_name': 'Neurooncology', 'score': 0.67081994}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8458216}, {'id': 'https://openalex.org/C2780103909', 'wikidata': 'https://www.wikidata.org/wiki/Q3875054', 'display_name': 'Neurooncology', 'level': 2, 'score': 0.67081994}, {'id': 'https://openalex.org/C2779338263', 'wikidata': 'https://www.wikidata.org/wiki/Q208414', 'display_name': 'Lymphoma', 'level': 2, 'score': 0.52865463}, {'id': 'https://openalex.org/C203522944', 'wikidata': 'https://www.wikidata.org/wiki/Q288322', 'display_name': 'Autophagy', 'level': 3, 'score': 0.4120389}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.34890246}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.322362}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.30057853}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.27400276}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D001343', 'descriptor_name': 'Autophagy', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001343', 'descriptor_name': 'Autophagy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001929', 'descriptor_name': 'Brain Edema', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D001929', 'descriptor_name': 'Brain Edema', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001929', 'descriptor_name': 'Brain Edema', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D019008', 'descriptor_name': 'Drug Resistance, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019008', 'descriptor_name': 'Drug Resistance, Neoplasm', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005938', 'descriptor_name': 'Glucocorticoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019586', 'descriptor_name': 'Intracranial Hypertension', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019586', 'descriptor_name': 'Intracranial Hypertension', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D019586', 'descriptor_name': 'Intracranial Hypertension', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013995', 'descriptor_name': 'Time', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1097/wco.0b013e32833e5a5d', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S177945262', 'display_name': 'Current Opinion in Neurology', 'issn_l': '1350-7540', 'issn': ['1350-7540', '1473-6551'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20962642', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.82, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 87, 'referenced_works': ['https://openalex.org/W1010417915', 'https://openalex.org/W102356689', 'https://openalex.org/W1517353469', 'https://openalex.org/W1544190631', 'https://openalex.org/W1568042534', 'https://openalex.org/W195781269', 'https://openalex.org/W1973138364', 'https://openalex.org/W1975295807', 'https://openalex.org/W1981528515', 'https://openalex.org/W1983216934', 'https://openalex.org/W1989786947', 'https://openalex.org/W1990503775', 'https://openalex.org/W1998210173', 'https://openalex.org/W1999179879', 'https://openalex.org/W2000297826', 'https://openalex.org/W2000948536', 'https://openalex.org/W2001589253', 'https://openalex.org/W2002056663', 'https://openalex.org/W2002315967', 'https://openalex.org/W2005169943', 'https://openalex.org/W2007919969', 'https://openalex.org/W2008106123', 'https://openalex.org/W2009916434', 'https://openalex.org/W2010243444', 'https://openalex.org/W2010450340', 'https://openalex.org/W2011203192', 'https://openalex.org/W2011366383', 'https://openalex.org/W2014498328', 'https://openalex.org/W2020896282', 'https://openalex.org/W2021456179', 'https://openalex.org/W2023709249', 'https://openalex.org/W2030573007', 'https://openalex.org/W2031026757', 'https://openalex.org/W2032080629', 'https://openalex.org/W2033369193', 'https://openalex.org/W2035409850', 'https://openalex.org/W2037646172', 'https://openalex.org/W2040010289', 'https://openalex.org/W2042007405', 'https://openalex.org/W2044672640', 'https://openalex.org/W2050682684', 'https://openalex.org/W2054461022', 'https://openalex.org/W2060549911', 'https://openalex.org/W2061878363', 'https://openalex.org/W2061929833', 'https://openalex.org/W2066792372', 'https://openalex.org/W2067399509', 'https://openalex.org/W2068475145', 'https://openalex.org/W2069729406', 'https://openalex.org/W2072260146', 'https://openalex.org/W2074658917', 'https://openalex.org/W2075959152', 'https://openalex.org/W2078581194', 'https://openalex.org/W2079325679', 'https://openalex.org/W2082981537', 'https://openalex.org/W2084856835', 'https://openalex.org/W2085286861', 'https://openalex.org/W2085404811', 'https://openalex.org/W2087669700', 'https://openalex.org/W2089081917', 'https://openalex.org/W2091135494', 'https://openalex.org/W2098940314', 'https://openalex.org/W2107621783', 'https://openalex.org/W2113906101', 'https://openalex.org/W2121006344', 'https://openalex.org/W2122687151', 'https://openalex.org/W2124483143', 'https://openalex.org/W2124596819', 'https://openalex.org/W2124716652', 'https://openalex.org/W2128687105', 'https://openalex.org/W2129617373', 'https://openalex.org/W2132539548', 'https://openalex.org/W2132697290', 'https://openalex.org/W2135178872', 'https://openalex.org/W2135453454', 'https://openalex.org/W2135907153', 'https://openalex.org/W2143737320', 'https://openalex.org/W2150080078', 'https://openalex.org/W2155943684', 'https://openalex.org/W2159941636', 'https://openalex.org/W2166696317', 'https://openalex.org/W2167033587', 'https://openalex.org/W2170891429', 'https://openalex.org/W2171133944', 'https://openalex.org/W2401545920', 'https://openalex.org/W57377733', 'https://openalex.org/W63790420'], 'related_works': ['https://openalex.org/W4290566354', 'https://openalex.org/W3149022029', 'https://openalex.org/W3030543547', 'https://openalex.org/W2923322377', 'https://openalex.org/W2899084033', 'https://openalex.org/W2748952813', 'https://openalex.org/W2319748744', 'https://openalex.org/W2163466967', 'https://openalex.org/W2009727862', 'https://openalex.org/W1967307117'], 'abstract_inverted_index': {'Glucocorticoids': [0], 'are': [1, 42], 'frequently': [2], 'used': [3, 46], 'in': [4, 68, 139, 147, 159], 'the': [5, 48, 64, 84, 148, 160], 'treatment': [6, 49, 122, 161], 'of': [7, 35, 37, 50, 66, 76, 86, 150, 162, 175, 177], 'patients': [8], 'with': [9, 115, 123, 129, 167], 'neurooncological': [10], 'disorders.': [11], 'This': [12], 'review': [13], 'addresses': [14], 'different': [15, 40], 'clinical': [16, 140], 'indications': [17], 'and': [18, 23, 112, 117, 137, 156, 171, 184], 'provides': [19], 'information': [20], 'on': [21], 'beneficial': [22], 'undesired': [24], 'effects': [25], 'exerted': [26], 'by': [27, 108], 'these': [28, 178], 'drugs.': [29], 'The': [30], 'most': [31], 'important': [32, 73], 'cellular': [33], 'mechanisms': [34], 'action': [36], 'glucocorticoids': [38, 81, 124], 'under': [39], 'conditions': [41], 'highlighted.Glucocorticoids': [43], 'have': [44, 62], 'been': [45], 'for': [47, 53, 142], 'lymphoid': [51], 'neoplasms': [52], 'decades.': [54], 'In': [55, 79], 'addition': [56], 'to': [57, 96], 'proapoptotic': [58], 'effects,': [59], 'recent': [60], 'studies': [61], 'delineated': [63], 'induction': [65], 'autophagy': [67], 'lymphoma': [69, 94], 'cells': [70, 95], 'as': [71], 'an': [72], 'alternative': [74], 'mode': [75], 'cell': [77], 'death.': [78], 'contrast,': [80], 'may': [82], 'reduce': [83], 'sensitivity': [85], 'tumor': [87, 164], 'cells,': [88, 91], 'including': [89, 132], 'glioma': [90], 'other': [92], 'than': [93, 144], 'chemotherapeutic': [97], 'agents.': [98], 'Corticosteroids': [99], 'also': [100, 126], 'provide': [101], 'transient': [102], 'relief': [103], 'from': [104], 'neurological': [105], 'symptoms': [106], 'caused': [107], 'increased': [109], 'intracranial': [110], 'pressure': [111], 'edema': [113], 'associated': [114, 128], 'primary': [116], 'secondary': [118], 'brain': [119, 163], 'tumors.': [120], 'However,': [121], 'is': [125, 182], 'commonly': [127], 'considerable': [130], 'side-effects': [131, 186], 'hyperglycemia,': [133], 'myopathy,': [134], 'osteoporosis,': [135], 'lymphopenia': [136], 'others.Although': [138], 'use': [141], 'more': [143], '40': [145], 'years': [146], 'field': [149], 'neurooncology,': [151], 'steroids': [152], 'remain': [153], 'a': [154], 'central': [155], 'essential': [157], 'part': [158], 'patients.': [165], 'Along': [166], 'improved': [168], 'therapeutic': [169], 'options': [170], 'prolonged': [172], 'life': [173], 'expectancy': [174], 'many': [176], 'patients,': [179], 'careful': [180], 'administration': [181], 'required': [183], 'long-term': [185], 'must': [187], 'be': [188], 'considered.': [189]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2014535178', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 11}, {'year': 2015, 'cited_by_count': 15}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-09T23:39:15.319272', 'created_date': '2016-06-24'}