Title: The carbon monoxide Bohr effect in hemoglobin from Thunnus thynnus
Abstract: The carbon monoxide Bohr effect of Thunnus thynnus hemoglobin was studied by the method of differential titrations. The results can be fitted by the simple model usually applied to mammalian hemoglobins, which assumes the presence of only two ligand-linked acid groups, one for the acid and one for the alkaline part of the effect. The values of ΔpK are considerably larger than those usually found in mammalian hemoglobins, being equal to 2.20 for the alkaline group and 1.20 for the acid group. The mean pK values for the two groups are consistent with the view that the two linked acid groups are a carboxyl in the acid range and an imidazole or an α-amino in the alkaline region.
Publication Year: 1966
Publication Date: 1966-04-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 18
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