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4302, 4398, 4411, 4424, 4439], 'the': [15, 158, 175, 190, 202, 212, 224, 228, 247, 390, 407, 422, 434, 444, 456, 460, 473, 506, 583, 587, 591, 634, 827, 832, 961, 974, 1058, 1100, 1211, 1488, 1509, 1605, 1631, 1675, 1721, 1748, 1773, 1791, 1860, 1867, 1874, 2057, 2104, 2115, 2145, 2160, 2177, 2278, 2285, 2360, 2376, 2395, 2438, 2447, 2454, 2468, 2481, 2570, 2622, 2634, 2647, 2706, 2753, 2823, 2826, 2842, 2866, 2872, 2876, 2909, 2917, 2927, 2931, 2962, 2967, 3230, 3237, 3240, 3258, 3279, 3296, 3302, 3306, 3318, 3338, 3356, 3359, 3365, 3394, 3398, 3421, 3522, 3559, 3634, 3649, 3657, 3681, 3698, 3743, 3748, 3769, 3774, 3790, 3813, 3838, 3842, 3854, 3872, 3889, 3906, 3933, 3945, 3960, 3966, 3989, 4057, 4091, 4096, 4176, 4198, 4204, 4211, 4248, 4266, 4324, 4393, 4400, 4406, 4413, 4419, 4426, 4434, 4441], 'GlcNAc': [16, 248], 'group': [17, 249, 477, 510], 'of': [18, 21, 42, 54, 161, 214, 250, 253, 274, 286, 393, 446, 466, 593, 957, 964, 979, 1044, 1051, 1062, 1511, 1558, 1742, 1750, 1761, 1764, 1780, 1790, 1793, 1859, 1870, 1979, 2073, 2099, 2109, 2118, 2179, 2202, 2207, 2287, 2369, 2446, 2585, 2624, 2630, 2667, 2696, 2812, 2825, 2835, 2845, 2855, 2860, 2875, 2880, 2905, 2921, 2926, 2930, 2986, 3150, 3251, 3260, 3295, 3301, 3337, 3371, 3379, 3436, 3463, 3472, 3524, 3550, 3564, 3615, 3633, 3652, 3659, 3686, 3710, 3721, 3729, 3733, 3841, 3876, 3891, 3894, 3898, 3936, 3968, 3973, 3993, 4029, 4066, 4079, 4100, 4109, 4140, 4274, 4278, 4297, 4312], 'two': [19, 251, 608, 782, 1093, 1515, 2071, 3325, 3361, 3626, 3645, 3665, 3839, 4279], 'series': [20, 252], 'acceptor': [22, 45, 57, 171, 208, 218, 254, 277, 289, 403, 440, 450, 1206, 1286, 1500, 1638, 1757, 2631, 3462, 3545, 3800, 3819, 3882, 4154, 4170, 4206, 4268], 'substrates': [23, 255, 2632], 'in': [24, 39, 51, 79, 98, 187, 199, 227, 256, 271, 283, 311, 330, 419, 431, 459, 590, 640, 840, 898, 927, 968, 1015, 1160, 1298, 1493, 1519, 1525, 1564, 1570, 1617, 1623, 1715, 1733, 1796, 1873, 2103, 2114, 2126, 2136, 2159, 2305, 2382, 2616, 2681, 2822, 2916, 3216, 3257, 3266, 3269, 3309, 3335, 3414, 3429, 3454, 3606, 3641, 3693, 3802, 3848, 3853, 4047, 4189, 4197, 4210, 4291], 'H.': [25, 63, 80, 99, 162, 257, 295, 312, 331, 394, 501, 557, 641, 662, 841, 970, 980, 1063, 1137, 1682, 1716, 1751, 1765, 1798, 1803, 2203, 2987, 2995, 3157, 3262, 3803], 'lipopolysaccharide:': [27, 259], 'βGal1,3βGlcNAc': [28, 260], '(Type': [29, 33, 261, 265], 'I)': [30, 262], 'or': [31, 50, 73, 263, 282, 305, 621, 624, 1145, 1458, 1556, 1608, 1711, 1723, 2600, 2891, 2947, 3228, 3243, 3440, 3557, 3783, 3797, 4098], 'βGal1,4βGlcNAc': [32, 264], 'II).': [34, 266], 'Fucose': [35, 267], 'is': [36, 211, 220, 268, 443, 452, 637, 901, 924, 1330, 1344, 1496, 1601, 1670, 2908, 3140, 3234, 3276, 3465, 3717, 3789, 3807, 3885, 4043, 4135, 4252], 'added': [37, 269], 'either': [38, 270], 'α1,3': [40, 87, 116, 272, 319, 348, 620, 1296, 1306, 1347, 2580, 3037, 3085, 3224, 3666, 3673, 3708, 3735, 3754, 3779, 3827, 3861, 3926, 3950, 3981, 4008, 4086], 'linkage': [41, 53, 273, 285], 'Type': [43, 55, 71, 74, 93, 106, 109, 148, 151, 166, 169, 203, 206, 275, 287, 303, 306, 325, 338, 341, 380, 383, 398, 401, 435, 438, 474, 507, 567, 570, 573, 576, 1316, 1319, 1325, 1339, 1606, 1609, 1633, 1636, 1726, 1729, 1892, 1896, 2595, 2601, 2889, 2894, 2906, 2942, 2948, 3048, 3051, 3460, 3481, 3484, 3495, 3506, 3541, 3568, 3570, 3795, 3798, 3880, 4115], 'II': [44, 75, 94, 107, 152, 170, 207, 276, 307, 326, 339, 384, 402, 439, 475, 1320, 1340, 1610, 1637, 1730, 3049, 3461, 3482, 3496, 3799], 'produce': [47, 59, 279, 291], 'Lewis': [48, 60, 280, 292, 479, 482, 512, 515, 594, 597, 602, 975, 1774, 1794, 3165, 3168, 3208, 3211], 'X': [49, 281, 480, 3166], 'α1,4': [52, 118, 284, 350, 622, 1308, 1333, 2582, 3039, 3675, 3727, 3756, 3785, 3868, 3907, 3928, 3952, 3985, 3999, 4010, 4032, 4039, 4051, 4069, 4081, 4101, 4128, 4255, 4295], 'I': [56, 72, 110, 149, 167, 204, 288, 304, 342, 381, 399, 436, 508, 1317, 1326, 1607, 1634, 1727, 3052, 3507, 3542, 3796, 3881, 4116], 'A,': [61, 293], 'respectively.': [62, 120, 294, 352], 'FucTs': [65, 129, 164, 216, 297, 361, 396, 448, 983, 1022, 1065, 1139, 1162, 1203, 1495, 1680, 1684, 1718, 1735, 1753, 1767, 1805, 1862, 2591, 2849, 3215, 3264, 3340, 3405, 3413, 3438, 3451, 3619, 3628, 3647, 3690, 4281, 4318], 'different': [67, 299, 969, 1313, 2994, 3808], 'strains': [68, 300, 503, 843, 972, 1983], 'have': [69, 301, 1142, 3083, 3223, 3489, 3938, 4031], 'distinct': [70, 302, 1205], 'substrate': [76, 125, 308, 357, 1611, 1731, 1758, 4117, 4155], 'specificities.': [77, 309], 'FucT': [78, 97, 310, 329, 785, 796, 839, 965, 1046, 1102, 1215, 1222, 1289, 1293, 1300, 1322, 1336, 1348, 1430, 1460, 1520, 1526, 1565, 1618, 1781, 1875, 2205, 2208, 2273, 2583, 2671, 2762, 2787, 2808, 2990, 3044, 3232, 3430, 3682, 3757, 3828, 4338, 4352], 'strain': [82, 101, 314, 333, 899, 928, 2127, 2137, 3159], 'NCTC11639': [83, 315, 844, 900, 1984], 'has': [84, 114, 316, 346, 4161, 4235], 'an': [85, 317, 836, 1332, 1346, 2288, 2749, 3511], 'exclusive': [86, 318, 1295, 3084], 'activity': [88, 320, 2640, 2649, 2657, 2859, 2868, 3086, 3147, 3225, 3700, 3709, 3728, 3780, 3862, 3919, 3982, 4000, 4082, 4129, 4296, 4394, 4407, 4420, 4435], 'because': [89, 321, 2920, 4232], 'it': [90, 113, 322, 345, 3046, 3788, 4021, 4037, 4042], 'recognizes': [91, 323], 'only': [92, 324], 'substrates,': [95, 327], 'whereas': [96, 328, 1335, 3355, 4034], 'UA948': [102, 334, 846, 929, 1986, 3946, 3974], 'can': [103, 335, 604, 2913, 3964], 'utilize': [104, 336], 'both': [105, 115, 337, 347, 1305, 3036, 3244, 3390, 3446, 3753, 3924, 4007, 4013], 'and': [108, 117, 137, 139, 150, 168, 189, 205, 340, 349, 369, 371, 382, 400, 421, 437, 481, 514, 601, 788, 790, 845, 960, 987, 1018, 1036, 1218, 1220, 1291, 1302, 1307, 1318, 1328, 1342, 1421, 1432, 1462, 1635, 1681, 1728, 1895, 1914, 1985, 2051, 2121, 2129, 2131, 2149, 2164, 2200, 2275, 2351, 2380, 2394, 2427, 2487, 2581, 2589, 2606, 2669, 2685, 2705, 2733, 2752, 2767, 2801, 2806, 2841, 2847, 3002, 3038, 3041, 3148, 3154, 3161, 3167, 3210, 3218, 3285, 3311, 3326, 3358, 3373, 3381, 3385, 3389, 3448, 3487, 3514, 3546, 3554, 3612, 3674, 3688, 3740, 3747, 3755, 3766, 3773, 3822, 3927, 3951, 4009, 4130, 4282, 4287, 4308, 4315], 'acceptors;': [111, 343], 'thus': [112, 344], 'activity,': [119, 351, 1309, 3829, 3869, 3986, 4011, 4033, 4256], 'To': [121, 353], 'identify': [122, 354, 1747], 'elements': [123, 355], 'conferring': [124, 356, 1499, 1725, 4114], 'specificity,': [126, 358], '12': [127, 359], 'chimeric': [128, 360, 2184, 2590, 2807, 2848, 2877, 3404, 3618, 3689, 4316], 'were': [130, 362, 1879, 1899, 1920, 1987, 2053, 2064, 2112, 2157, 2169, 2187, 2210, 2270, 2294, 2378, 2397, 2420, 2451, 2478, 2493, 2592, 2676, 2701, 2708, 2721, 2746, 2755, 2765, 2850, 2884, 2935, 2958, 3006, 3406, 3518, 3629, 3832, 3930], 'constructed': [131, 363], 'by': [132, 223, 364, 455, 616, 628, 1778, 1881, 1902, 1964, 1989, 1994, 2066, 2645, 2651, 2703, 2864, 2871, 2960, 3236, 3305, 3521, 3888, 3896, 3944, 3971, 4341, 4355], 'domain': [133, 365, 1043, 1061, 1091, 1425, 1710, 2061, 3422, 3653, 3817, 3963], 'swapping': [134, 366, 1426, 2062, 3423], 'between': [135, 367, 1429, 1459, 1678, 2799, 3282, 3324, 3644], '11639FucT': [136, 368, 2846, 3078, 3380, 3464, 3486, 3553, 3711, 3744, 3775, 3899, 3937, 3961], 'UA948FucT': [138, 370, 2794, 2836, 3034, 3310, 3343, 3346, 3382, 3474, 3488, 3498, 3530, 3555, 3722, 3730, 3749, 3770, 3877, 3895, 3917, 3994, 4030, 4068, 4110, 4142], 'characterized': [140, 372], 'for': [141, 373, 586, 794, 1498, 1755, 1809, 2153, 2272, 2356, 2432, 2480, 2678, 2817, 3145, 3342, 3445, 3459, 3480, 3540, 4113, 4229, 4254, 4330], 'their': [142, 374, 1154, 2197, 3761], 'ability': [143, 375], 'acceptors.': [153, 385], 'Our': [154, 386, 4103, 4244], 'results': [155, 387, 3852], 'indicate': [156, 388, 4105, 4246], 'that': [157, 389, 1213, 1487, 1508, 2191, 2626, 2854, 2912, 3420, 3471, 3529, 3720, 3793, 3871, 3988, 4024, 4045, 4090, 4106, 4123, 4131, 4139, 4146, 4168, 4192, 4203, 4247], 'C-terminal': [159, 178, 391, 410, 1037, 1041, 3319, 3560, 3873], 'region': [160, 392, 1492, 1722, 3275, 3291, 3316, 3991, 4094, 4251], 'controls': [165, 201, 397, 433, 3794], 'specificity.': [172, 404, 1501, 1612, 3820, 3883, 4118, 4156], 'In': [173, 405, 661, 1132, 1502, 1801, 3655, 3696, 3759, 3958, 4002, 4071], 'particular,': [174, 406, 1503], 'highly': [176, 408, 1094, 3636], 'divergent': [177, 409, 1868, 3274, 3315, 3637, 4059, 4093, 4250], 'portion,': [179, 411], 'seven': [180, 412, 3261], 'amino': [181, 193, 413, 425, 1052, 1516, 1561, 1712, 3366], 'acids': [182, 194, 414, 426, 1517], 'DNPFIFC': [183, 415], 'at': [184, 196, 416, 428, 1153, 1224, 1674, 2144, 2296, 2364, 2597, 2603, 2608, 2730, 2741, 2898, 2944, 2950, 3278, 3408, 3863, 4014, 4175, 4216, 4323], 'positions': [185, 197, 417, 429], '347–353': [186, 418], '11639FucT,': [188, 420], 'corresponding': [191, 423, 1522, 1567, 1620], '10': [192, 424, 992, 2316, 3327, 4019], 'CNDAHYSALH': [195, 427], '345–354': [198, 430], 'UA948FucT,': [200, 432], 'recognition.': [209, 441], 'This': [210, 442, 1090, 1783, 3806, 3884, 4088, 4201], 'opposite': [213, 445], 'mammalian': [215, 447, 632, 1045, 1135], 'where': [217, 449, 3812], 'preference': [219, 451], 'determined': [221, 453, 2452, 2766, 2885, 2936], 'primarily': [222, 454, 1345], 'N-terminal': [225, 457, 1029, 1143, 1489, 3814, 4212], 'residues': [226, 458, 1714, 1724, 2156, 3283, 4027, 4046, 4107, 4149, 4230], 'hypervariable': [229, 461, 1033, 1490, 3815], 'stem': [230, 462, 1034, 1491, 3816], 'domain.': [231, 463], 'lipopolysaccharide': [465, 3163], 'contains': [469, 1092, 3317, 3347], 'fucosylated': [470], 'oligosaccharides,': [471], 'predominantly': [472, 1331], 'blood': [476, 509], 'antigens': [478, 511, 598], 'Y': [483, 600, 3169], '(1Wirth': [484], 'H.P.': [485, 530, 680], 'Yang': [486, 531], 'M.': [487, 489, 532, 752, 1257, 1377, 1814], 'Karita': [488], 'Blaser': [490, 533], 'M.J.': [491, 534], 'Infect.': [492, 3198], 'Immun.': [493, 3199], '1996;': [494, 1111, 1473, 2553], '64:': [495], '4598-4605Crossref': [496], 'PubMed': [497, 552, 656, 720, 775, 810, 866, 890, 916, 949, 1006, 1085, 1114, 1127, 1182, 1197, 1247, 1277, 1367, 1397, 1416, 1453, 1481, 1551, 1596, 1663, 1704, 1825, 1839, 1851, 2015, 2234, 2258, 2413, 2517, 2541, 2556, 3022, 3073, 3106, 3134, 3203], 'Google': [498, 555, 659, 723, 778, 813, 869, 893, 919, 952, 1009, 1088, 1115, 1130, 1185, 1200, 1248, 1280, 1368, 1400, 1419, 1456, 1484, 1554, 1599, 1666, 1707, 1828, 1842, 1854, 2018, 2237, 2261, 2416, 2520, 2544, 2559, 3025, 3076, 3109, 3137, 3204], 'Scholar).': [499, 556, 660, 814, 894, 953, 1010, 1089, 1131, 1201, 1667, 1855, 2019, 2047, 2096, 2417, 2560, 3077, 3138], 'Some': [500], 'also': [504, 3669, 4136], 'express': [505, 3164], 'A': [513, 2033, 2082, 2139, 2331, 2561, 2780, 3209], 'B': [516, 3212], '(2Monteiro': [517], 'M.A.': [518, 3175], 'Chan': [519, 849, 2217, 2500, 3089], 'K.H.': [520], 'Rasko': [521, 647, 799, 905], 'D.A.': [522, 648, 800, 872, 906, 931, 1067, 1164, 1686, 2240, 2523, 3055], 'Taylor': [523, 649, 765, 803, 853, 877, 909, 936, 1072, 1169, 1691, 1995, 2221, 2245, 2504, 2528, 3060, 3093], 'D.E.': [524, 650, 766, 804, 854, 878, 910, 937, 1073, 1170, 1692, 1999, 2222, 2246, 2505, 2529, 3061, 3094], 'Zheng': [525, 3180], 'P.Y.': [526], 'Appelmelk': [527], 'B.J.': [528, 3171], 'Wirth': [529], 'Hynes': [535], 'S.O.': [536], 'Moran': [537], 'A.P.': [538], 'Perry': [539, 3192], 'M.B.': [540, 3193], 'J.': [541, 688, 855, 879, 938, 1002, 1074, 1171, 1238, 1266, 1358, 1386, 1442, 1470, 1540, 1585, 1652, 1693, 1835, 1847, 2009, 2028, 2077, 2223, 2247, 2326, 2506, 2530, 3062, 3095, 3123], 'Biol.': [542, 856, 880, 939, 1075, 1172, 1239, 1267, 1359, 1387, 1443, 1471, 1541, 1586, 1653, 1694, 1821, 2224, 2248, 2507, 2531, 3063, 3096, 3124], 'Chem.': [543, 857, 881, 940, 1076, 1173, 1240, 1268, 1360, 1388, 1444, 1472, 1542, 1587, 1654, 1695, 1820, 2225, 2249, 2508, 2532, 2552, 3064, 3097, 3125], '1998;': [544, 1124, 1194, 1543], '273:': [545, 1544], '11533-11543Abstract': [546], 'Full': [547, 549, 861, 863, 885, 887, 944, 946, 1080, 1082, 1177, 1179, 1244, 1272, 1274, 1364, 1392, 1394, 1448, 1450, 1476, 1478, 1546, 1548, 1591, 1593, 1658, 1660, 1699, 1701, 2229, 2231, 2253, 2255, 2512, 2514, 2536, 2538, 3068, 3070, 3101, 3103, 3129, 3131], 'Text': [548, 550, 862, 864, 886, 888, 945, 947, 1081, 1083, 1178, 1180, 1245, 1273, 1275, 1365, 1393, 1395, 1449, 1451, 1477, 1479, 1547, 1549, 1592, 1594, 1659, 1661, 1700, 1702, 2230, 2232, 2254, 2256, 2513, 2515, 2537, 2539, 3069, 3071, 3102, 3104, 3130, 3132], 'PDF': [551, 865, 889, 948, 1084, 1181, 1246, 1276, 1366, 1396, 1452, 1480, 1550, 1595, 1662, 1703, 2233, 2257, 2516, 2540, 3072, 3105, 3133], 'Scopus': [553, 657, 721, 776, 811, 867, 891, 917, 950, 1007, 1086, 1128, 1183, 1198, 1278, 1398, 1417, 1454, 1482, 1552, 1597, 1664, 1705, 1826, 1840, 1852, 2016, 2235, 2259, 2414, 2518, 2542, 2557, 3023, 3074, 3107, 3135], '(153)': [554], 'fucosyltransferases': [559], '(FucTs)': [560], '1The': [561], 'abbreviations': [562], 'used': [563, 639, 2113, 2271, 2479, 2574, 3509], 'are:': [564], 'FucT,': [565, 1334, 1625], 'fucosyltransferase;': [566], 'I,': [568], 'Galβ1,3GlcNAc;': [569], 'II,': [571], 'Galβ1,4GlcNAc;': [572], 'I-R,': [574], 'Galβ1,3GlcNAc-O(CH2)8CO2CH3;': [575], 'II-R,': [577], 'Galβ1,4GlcNAc-O(CH2)8CO2CH3;': [578], 'WT,': [579], 'wild': [580, 2586, 3551, 4313], 'type.': [581], 'are': [582, 984, 1012, 1023, 1158, 1806, 2101, 3220, 3255, 3323, 3383, 3452, 3691, 3844, 4111, 4173, 4289], 'enzymes': [584, 986], 'responsible': [585, 1497, 1754], 'last': [588, 3360], 'steps': [589, 2072], 'synthesis': [592, 1812], 'antigens.': [595], 'Difucosylated': [596], '(Lewis': [599], 'B)': [603], 'be': [605, 1737, 2914, 3247, 4121, 4262], 'synthesized': [606, 1880], 'via': [607], 'pathways:': [609], 'terminal': [610, 629], 'fucosylation': [611, 618, 626], '(in': [612, 619], 'α1,2': [613, 795], 'linkage)': [614, 623], 'followed': [615, 627], 'subterminal': [617, 625], 'fucosylation.': [630], 'Unlike': [631], 'cells,': [633], 'latter': [635], 'pathway': [636], 'predominately': [638], '(3Wang': [643], 'G.': [644, 746, 798, 874, 904, 933, 1069, 1166, 1688, 2242, 2404, 2525, 3057], 'Ge': [645], 'Z.': [646, 848, 1465, 2216, 2499, 3088], 'Mol.': [651, 805, 911], 'Microbiol.': [652, 806, 912], '2000;': [653, 882, 941, 1077, 1174, 1696, 2250, 2533, 3065], '36:': [654, 2411], '1187-1196Crossref': [655], '(118)': [658], 'genomes': [664], '(4Tomb': [665], 'J.F.': [666], 'White': [667], 'O.': [668, 1904], 'Kerlavage': [669], 'A.R.': [670], 'Clayton': [671, 3176], 'R.A.': [672, 726], 'Sutton': [673], 'G.G.': [674], 'Fleischmann': [675], 'R.D.': [676], 'Ketchum': [677], 'K.A.': [678], 'Klenk': [679], 'Gill': [681], 'S.': [682, 694, 1535, 1537, 2547], 'Dougherty': [683], 'B.A.': [684, 1410, 1469, 1539], 'Nelson': [685], 'K.': [686, 706], 'Quackenbush': [687], 'Zhou': [689], 'L.': [690, 1467], 'Kirkness': [691], 'E.F.': [692], 'Peterson': [693], 'Loftus': [695], 'B.': [696, 740, 1000, 1831], 'Richardson': [697], 'D.': [698, 760], 'Dodson': [699], 'R.': [700, 758, 802, 908, 1107, 1120, 1190, 1261, 1263, 1265, 1381, 1383, 1385, 1578, 1580, 1582, 1645, 1647, 1649, 1833], 'Khalak': [701], 'H.G.': [702], 'Glodek': [703], 'A.': [704, 750, 1109, 1122, 1192, 1251, 1253, 1371, 1373, 1584, 1651], 'McKenney': [705], 'Fitzegerald': [707], 'L.M.': [708], 'Lee': [709], 'N.': [710], 'Adams': [711], 'M.D.': [712], 'Venter': [713], 'J.C.': [714], 'et': [715, 1996], 'al.Nature.': [716], '1997;': [717, 858, 1003, 1269, 1389, 1822, 2226, 2410, 2509, 3098, 3126], '388:': [718], '539-547Crossref': [719], '(3028)': [722], 'Scholar,': [724, 870, 1116, 1186, 1249, 1369, 1401, 1829, 1843, 2238, 2521, 2545, 3110], '5Alm': [725], 'Ling': [727], 'L.S.': [728], 'Moir': [729], 'D.T.': [730], 'King': [731], 'B.L.': [732, 744], 'Brown': [733], 'E.D.': [734], 'Doig': [735], 'P.C.': [736], 'Smith': [737, 1232, 1352], 'D.R.': [738], 'Noonan': [739], 'Guild': [741], 'B.C.': [742], 'deJonge': [743], 'Carmel': [745], 'Tummino': [747], 'P.J.': [748], 'Caruso': [749], 'Uria-Nickelsen': [751], 'Mills': [753, 761], 'D.M.': [754], 'Ives': [755], 'C.': [756, 1105, 1118, 1188], 'Gibson': [757, 3014], 'Merberg': [759], 'S.D.': [762], 'Jiang': [763], 'Q.': [764], 'Vovis': [767], 'G.F.': [768], 'Trust': [769], 'T.J.': [770, 3015], 'Nature.': [771], '1999;': [772, 807, 913, 1588, 1655, 1836, 1848, 3200], '397:': [773], '176-180Crossref': [774], '(1601)': [777], 'Scholar),': [779, 920, 1281, 1708], 'there': [780, 1669], 'exist': [781], 'homologous': [783], 'genes,': [786], 'futA': [787, 828, 2058, 2125, 2135, 2185, 3238], 'futB,': [789], 'one': [791], 'gene': [792, 897, 923, 2279], 'futC': [793, 896], '(6Wang': [797, 903], 'Sherburne': [801, 907], '31:': [808, 914], '1265-1274Crossref': [809, 915], '(116)': [812, 918], 'These': [815], 'three': [816, 2400, 3635], 'fut': [817, 958], 'genes': [818, 959, 2186, 2209], 'do': [819, 1140, 4220], 'not': [820, 831, 925, 1141, 2830, 3207, 3229, 3425, 3519, 3845, 4159, 4194, 4221], 'always': [821], 'encode': [822], 'functional': [823, 902, 926], 'proteins.': [824], 'For': [825, 1208, 2804], 'instance,': [826, 1209], 'gene,': [829, 834, 3239, 3242], 'but': [830, 921, 3206, 3983, 4158, 4257], 'futB': [833, 3241], 'encodes': [835], 'active': [837, 3231], '(7Ge': [847, 2215, 2498, 3087], 'N.W.': [850, 2218, 2501, 3090], 'Palcic': [851, 875, 934, 1070, 1167, 1258, 1378, 1689, 2219, 2243, 2502, 2526, 2548, 3058, 3091], 'M.M.': [852, 876, 935, 1071, 1168, 1259, 1379, 1690, 2220, 2244, 2503, 2527, 2549, 3059, 3092], '272:': [859, 1270, 1390, 2227, 2510, 3099, 3127], '21357-21363Abstract': [860, 2228, 2511, 3100], '(109)': [868, 2236, 2519, 3108], '8Rasko': [871, 2239, 2522], 'Wang': [873, 932, 1068, 1165, 1687, 2241, 2524, 3056], '275:': [883, 942, 1078, 1175, 1697, 2251, 2534, 3066], '4988-4994Abstract': [884, 943, 1079, 1176, 1698, 2252, 2535, 3067], '(71)': [892, 951, 1087, 1184, 1706, 2260, 2543, 3075], 'this': [922, 1743, 3352, 4048, 4217], '(8Rasko': [930, 1066, 1163, 1685, 3054], 'on/off': [955], 'status': [956], 'various': [962, 1871], 'levels': [963, 2844, 3410], 'activities': [966, 2584, 3040, 3676, 3929, 3953], 'exhibited': [967, 3824, 3913, 4006], 'determine': [973, 4399, 4412, 4425, 4440], 'antigen': [976, 1775, 1795], 'expression': [977, 1776, 2833, 2843, 2873, 3432, 3684, 4339, 4353], 'patterns': [978], 'lipopolysaccharide.': [982], 'inverting': [985], 'belong': [988], 'glycosyltransferase': [990], 'family': [991], '(9Campbell': [993], 'J.A.': [994, 2001], 'Davies': [995], 'G.J.': [996], 'Bulone': [997], 'V.': [998], 'Henrissat': [999], 'Biochem.': [1001], '326:': [1004], '929-939Crossref': [1005], '(630)': [1008], 'They': [1011], 'widely': [1013], 'expressed': [1014, 3407, 3834], 'vertebrates,': [1016], 'invertebrates,': [1017], 'bacteria.': [1019], 'Mammalian': [1020], 'Golgi-anchored': [1024], 'proteins': [1025, 2707, 3391], 'with': [1026, 1057, 1134, 2070, 2263, 2299, 2422, 2459, 2594, 2723, 2783, 2896, 2941, 2974, 3027, 3299, 3330, 3351, 3439, 3494, 3531, 3556, 3781, 4403, 4416, 4429, 4444], 'short': [1027], 'cytoplasmic': [1028], 'tails,': [1030], 'transmembrane': [1031, 1146], 'segments,': [1032], 'domains,': [1035], 'catalytic': [1038, 1042, 1060, 3947, 3962], 'domains.': [1039], 'displays': [1047, 3035, 4185], 'a': [1048, 1559, 1787, 2180, 2464, 2576, 3331, 3476, 3500, 3525, 3532, 3536, 3607, 3914, 3939, 3955, 4162, 4186, 4227, 4236, 4320], 'low': [1049, 2923, 3252, 3826, 3855, 4015, 4127, 4301, 4397, 4410, 4423, 4438], 'level': [1050, 2834, 2874, 3685, 3865], 'acid': [1053, 1562, 1713, 3367], 'sequence': [1054, 1228, 1672, 2141, 3253, 3334, 3368], 'identity': [1055, 1229, 1673, 3254], '(40%)': [1056], 'internal': [1059, 3349, 3662, 3990], 'conserved': [1095, 3332, 3661], 'regions,': [1096], 'referred': [1097], 'as': [1099, 1512, 1514, 1992, 2212, 2463, 2495, 2575, 3079, 3081, 3411, 3510], 'motifs': [1103, 3667], '(10Breton': [1104], 'Oriol': [1106, 1119, 1189, 1262, 1382, 1579, 1646], 'Imberty': [1108, 1121, 1191], 'Glycobiology.': [1110, 1123, 1193, 1411], '6:': [1112], 'vii-xiiCrossref': [1113], '11Breton': [1117, 1187], '8:': [1125, 1195], '87-94Crossref': [1126, 1196], '(114)': [1129, 1199], 'comparison': [1133], 'FucTs,': [1136, 3811], 'tails': [1144], 'domains;': [1147], 'instead,': [1148], 'they': [1149, 1282, 1311, 3831], 'contain': [1150, 3364], 'heptad': [1151, 3297, 3320, 3328, 3362, 3874, 3892, 3934, 3969], 'repeats': [1152, 3329, 3350, 3363, 3875, 3893, 3935, 3970], 'C': [1155, 3750, 3776, 3791], 'terminus,': [1156, 3777, 4178], 'which': [1157, 2365, 2820, 3716, 3851, 3902], 'absent': [1159], 'human': [1161, 1214, 1494, 1679, 1734, 3043, 3810], 'exhibit': [1204, 1312], 'preferences.': [1207], 'despite': [1210], 'fact': [1212], 'III,': [1216], 'V,': [1217, 1619, 3045], 'VI': [1219, 1290, 1433], 'bovine': [1221, 1292, 1571, 1624, 2460], 'share': [1223], 'least': [1225], '70%': [1226], 'protein': [1227, 1942, 2444, 2456, 2562, 2653, 2698, 2798, 2814, 3233, 3683], '(12Weston': [1230], 'B.W.': [1231, 1351], 'P.L.': [1233, 1353], 'Kelly': [1234, 1354, 1436], 'R.J.': [1235, 1355, 1437], 'Lowe': [1236, 1356, 1440], 'J.B.': [1237, 1357, 1441], '1992;': [1241, 1361], '267:': [1242, 1362], '24575-24584Abstract': [1243, 1363], '13Oulmouden': [1250, 1370], 'Wierinckx': [1252, 1372], 'Petit': [1254, 1374, 1575, 1642], 'J.M.': [1255, 1375, 1533, 1576, 1643], 'Costache': [1256, 1376], 'Mollicone': [1260, 1380, 1577, 1644], 'Julien': [1264, 1384, 1581, 1648], '8764-8773Abstract': [1271, 1391], '(69)': [1279, 1399], 'displayed': [1283, 3778, 3860], 'strikingly': [1284], 'distinctive': [1285], 'specificity': [1287, 1639, 1732, 3149, 3801, 4171, 4207], 'patterns.': [1288], 'display': [1294], 'activity;': [1297], 'contrast,': [1299, 3760, 3959, 4003, 4072], 'III': [1301, 1323, 1431, 1461, 1521], 'V': [1303, 1337, 1463, 1566], 'show': [1304], 'although': [1310, 3830, 3910, 4012], 'preferences': [1314], 'toward': [1315], 'substrates.': [1321], 'favors': [1324, 3047], 'acceptors': [1327, 1341, 3053], 'therefore': [1329], 'prefers': [1338], 'hence': [1343], '(Refs.': [1349], '12Weston': [1350], '14de': [1402], 'Vries': [1403], 'T.': [1404, 3183], 'Knegtel': [1405], 'R.M.': [1406], 'Holmes': [1407, 1530], 'E.H.': [1408, 1531], 'Macher': [1409, 1468, 1538], '2001;': [1412], '11': [1413], '(R):': [1414], '119R-1128Crossref': [1415], '(157)': [1418], 'Scholar': [1420], 'references': [1422], 'therein).': [1423], 'experiments': [1427, 2063], 'performed': [1428, 2494, 2791], '(15Legault': [1434], 'D.J.': [1435], 'Natsuka': [1438], 'Y.': [1439], '1995;': [1445], '270:': [1446], '20987-20996Abstract': [1447], '(80)': [1455], 'Scholar)': [1457, 1485, 1555, 1600, 2262, 2345, 3026, 3205], '(16Xu': [1464], 'Vo': [1466], '271:': [1474], '8818-8823Abstract': [1475], '(78)': [1483], 'demonstrated': [1486], 'site-directed': [1504], 'mutagenesis': [1505], 'data': [1506, 2965, 3143, 4104, 4245], 'showed': [1507], 'substitution': [1510, 3890], 'few': [1513], '(His87-Ile88': [1518], 'Asn86-Thr87': [1524], 'V)': [1527], '(17Nguyen': [1528], 'A.T.': [1529], 'Whitaker': [1532], 'Ho': [1534], 'Shetterly': [1536], '25244-25249Abstract': [1545], '(42)': [1553], 'replacement': [1557], 'single': [1560], '(Trp111': [1563], 'Arg115': [1569], 'FucT)': [1572], '(18Dupuy': [1573, 1640], 'F.': [1574, 1641], 'Maftah': [1583, 1650], '274:': [1589, 1656], '12257-12262Abstract': [1590, 1657], '(70)': [1598, 1665], 'able': [1602, 1627], 'change': [1604], 'adjacent': [1614], 'residue': [1615, 4181], 'Asp112': [1616], 'Glu116': [1622], 'was': [1626, 1745, 1885, 1909, 1930, 1945, 1951, 1962, 1970, 2022, 2142, 2371, 2573, 2614, 2643, 2662, 2790, 2815, 2821, 2837, 2862, 3508, 3648, 3668, 3703, 3712, 3731, 3995, 4299, 4334, 4348, 4395, 4408, 4421, 4436], 'further': [1629, 3886, 4151, 4196], 'modulate': [1630], 'relative': [1632, 2852], 'Because': [1668, 2925, 3156], 'no': [1671, 1709, 2192, 3141, 3784, 3984], 'N': [1676, 3280, 3745, 3771, 4177], 'terminus': [1677, 3281, 3746, 3751, 3772, 3792], 'correspond': [1719], 'could': [1736, 1784, 1863], 'identified.': [1738], 'main': [1740], 'goal': [1741], 'study': [1744, 2919], 'determinants': [1749, 4172, 4208, 4269], 'discriminating': [1756], 'preference.': [1759], 'Characterization': [1760], 'structure-function': [1762], 'relationships': [1763], 'would': [1768], 'enable': [1769], 'us': [1770, 1865], 'manipulate': [1772], 'pattern': [1777], 'mutation': [1779, 2193], 'genes.': [1782], 'lead': [1785], 'clearer': [1788], 'understanding': [1789, 1858], 'role': [1792, 4228], 'persistent': [1797], 'infection.': [1800], 'addition,': [1802, 3656, 3697], 'promising': [1807], 'candidates': [1808], 'chemoenzymatic': [1810], 'glycoconjugate': [1811], '(19Meldal': [1813], 'St.': [1815], 'Hilaire': [1816], 'P.M.': [1817], 'Curr.': [1818], 'Opin.': [1819], '1:': [1823], '552-563Crossref': [1824], '(54)': [1827], '20Ernst': [1830], 'Oehrlein': [1832], 'Glycoconj.': [1834, 1846], '16:': [1837, 1849], '161-170Crossref': [1838], '(29)': [1841], '21Johnson': [1844], 'K.F.': [1845], '141-146Crossref': [1850], '(72)': [1853], 'Finally,': [1856], 'better': [1857], 'bacterial': [1861], 'help': [1864], 'understand': [1866], 'evolution': [1869], 'lineages': [1872], 'kingdom.': [1876], 'Materials—The': [1877], 'primers': [1878, 2049, 2100, 2111, 2147, 2162], 'Invitrogen.': [1882], 'pGEM-T': [1883, 2175], 'vector': [1884, 2174, 2572], 'obtained': [1886, 1931, 1952, 1971, 2644, 2851, 2959], 'Promega': [1888], 'Co.': [1889, 1975], '(Madison,': [1890], 'WI).': [1891, 3033], 'II-R': [1893, 2596, 2890, 2907, 2943], '(βGal1–4βGlcNAc-O-(CH2)8CO2CH3)': [1894], 'I-R': [1897, 2602, 2895, 2949], '(βGal1–3βGlcNAc-O-(CH2)8CO2CH3)': [1898], 'kindly': [1900], 'provided': [1901], 'Dr.': [1903], 'Hindsgaul.': [1905], 'Anti-penta-histidine': [1906], 'monoclonal': [1907, 2728], 'antibody': [1908, 2725, 2735], 'purchased': [1910, 1946], 'Qiagen.': [1912], 'GDP-fucose': [1913, 2607, 2897, 2940], 'horseradish': [1915], 'peroxidase-conjugated': [1916, 2737], 'goat': [1917, 2738], 'anti-mouse': [1918], 'IgG': [1919], 'Sigma.': [1922], '[3H]GDP-fucose': [1923, 2611], '(0.1': [1924], 'mCi': [1925], 'ml–1,': [1926], '17.3': [1927], 'Ci': [1928], 'mmol–1)': [1929], 'American': [1933], 'Radiolabeled': [1934], 'Chemicals': [1935], 'Inc.': [1936, 1956, 2980], '(St.': [1937], 'Louis,': [1938], 'MO).': [1939], 'BCA': [1941, 2455], 'assay': [1943, 2457], 'kit': [1944, 1961], 'Pierce.': [1948], 'Nitrocellulose': [1949], 'membrane': [1950, 2476, 2713], 'Micron': [1954], 'Separation': [1955], '(Westboro,': [1957], 'MA).': [1958], 'ECL': [1960, 2750], 'supplied': [1963], 'Amersham': [1965], 'Biosciences.': [1966], 'BioMax': [1967, 2758], 'MR': [1968, 2759], 'film': [1969], 'Eastman': [1973], 'Kodak': [1974], '(Rochester,': [1976], 'NY).': [1977], 'Cloning': [1978], 'Chimeric': [1980, 2670, 3374, 3616], 'FucTs—H.': [1981], 'cultured': [1988], 'standard': [1990, 2025, 2465, 2781], 'methods,': [1991], 'described': [1993, 2213, 2496], 'al.': [1997], '(22Taylor': [1998], 'Hargreaves': [2000], 'Ng': [2002], 'L.K.': [2003], 'Sherbaniuk': [2004], 'R.W.': [2005], 'Jewell': [2006], 'L.D.': [2007], 'Am.': [2008], 'Clin.': [2010], 'Pathol.': [2011], '1987;': [2012], '87:': [2013], '49-54Crossref': [2014], '(55)': [2017], 'Chromosomal': [2020], 'DNA': [2021], 'isolated': [2023], 'following': [2024], 'protocol': [2026], '(23Sambrook': [2027, 2076, 2325], 'Russell': [2029, 2078, 2327], 'D.W.': [2030, 2079, 2328], 'Molecular': [2031, 2080, 2329], 'Cloning:': [2032, 2081, 2330], 'Laboratory': [2034, 2041, 2083, 2090, 2332, 2339], 'Manual.': [2035, 2084, 2333], '3rd': [2036, 2085, 2334], 'Ed.': [2037, 2086, 2335], 'Cold': [2038, 2043, 2087, 2092, 2336, 2341], 'Spring': [2039, 2044, 2088, 2093, 2337, 2342], 'Harbor': [2040, 2089, 2338], 'Press,': [2042, 2091, 2340], 'Harbor,': [2045, 2094, 2343], 'NY2000Google': [2046, 2095, 2344], 'Two': [2048, 2107], 'BM11': [2050], 'BM12': [2052], 'designed': [2054], 'amply': [2056], 'gene.': [2059], 'accomplished': [2065], 'primer': [2067], 'overlap': [2068], 'extension': [2069], 'sequential': [2074], 'PCR': [2075, 2167], 'sequences': [2098, 2991, 3308], 'available': [2102, 3144], 'supplemental': [2105], 'data.': [2106], 'pairs': [2108], 'proximal': [2110], 'second': [2116, 3290, 4058, 4092, 4249], 'step': [2117], 'PCR:': [2119], 'BM91': [2120, 2148], 'BM77,': [2122], 'complementary': [2123, 2133], '11639;': [2128], 'BM101': [2130], 'BM87,': [2132], 'UA948.': [2138], 'Shine-Dalgarno': [2140], 'included': [2143, 2158, 2615], 'sense': [2146], 'BM101.': [2150], 'codons': [2152], 'six': [2154, 2784], 'histidine': [2155], 'antisense': [2161], 'BM77': [2163], 'BM87.': [2165], 'products': [2168], 'cloned': [2170], 'into': [2171], 'A/T': [2172], 'cloning': [2173], 'under': [2176, 2284], 'control': [2178, 2286], 'T7': [2181, 2281], 'promoter.': [2182, 2291], 'Cloned': [2183], 'sequenced': [2188], 'assure': [2190], 'had': [2194, 3475, 3499, 3535, 3752, 3979], 'occurred': [2195], 'during': [2196], 'construction.': [2198], 'Induction': [2199], 'Expression': [2201, 3370], 'Genes—Expression': [2206], 'induced': [2211], 'previously': [2214, 2497], 'minor': [2264], 'modifications.': [2265], 'Escherichia': [2266], 'coli': [2267, 2567], 'HMS174DE3': [2268, 2565, 3415], 'cells': [2269, 2293, 2396, 2419, 2568, 3416], 'expression,': [2274], 'DE3': [2276], 'carries': [2277], 'encoding': [2280], 'RNA': [2282], 'polymerase': [2283], 'isopropyl-β-d-thiogalactopyranoside-induced': [2289], 'lactose': [2290], 'grown': [2295], '30': [2297], '°C': [2298], 'vigorous': [2300], 'shaking': [2301], '(200': [2302, 2353, 2424], 'rpm': [2303], 'min–1)': [2304], 'SOC': [2306], 'medium': [2307], '(20%': [2308], 'tryptone,': [2309], '5%': [2310], 'yeast': [2311], 'extract,': [2312], '0.05%': [2313], '(w/v)': [2314, 2683, 2687], 'NaCl,': [2315], 'mm': [2317, 2320, 2323, 2368, 2391, 2599, 2605, 2888, 2893, 2904, 2946, 2952], 'MgCl2,': [2318], '2.5': [2319], 'KCl,': [2321], '20': [2322, 2433], 'glucose)': [2324], 'including': [2346, 2901, 2953], 'ampicillin': [2347], '(100': [2348], 'μg': [2349, 2354, 2425, 2811], 'ml–1)': [2350, 2355, 2426, 2431], 'rifampicin': [2352], '2': [2357, 2903, 2945], 'h': [2358], 'until': [2359], 'A600': [2361], 'reached': [2362, 2915], '∼0.3,': [2363], 'point': [2366], '1': [2367, 2628], 'isopropyl-β-d-thiogalactopyranoside': [2370], 'added.': [2372], 'After': [2373], '4': [2374], 'h,': [2375], 'cultures': [2377], 'centrifuged': [2379], 'resuspended': [2381], 'HEPES': [2383], 'buffer': [2384], '(20': [2385], 'mm,': [2386, 3467], 'pH': [2387], '7.0,': [2388], 'containing': [2389, 2569, 2693, 2796, 3622, 3664, 3742, 3768, 4026], '0.5': [2390], 'phenylmethanesulfonyl': [2392], 'fluoride),': [2393], 'lysed': [2398], 'using': [2399, 2453, 2748, 2769, 2792, 2886, 2937, 2970, 3008], 'freeze-thaw': [2401, 2440], 'cycles': [2402], '(24Wang': [2403], 'Rahman': [2405], 'M.S.': [2406], 'Humayun': [2407], 'M.Z.': [2408], 'Biochemistry.': [2409], '9486-9492Crossref': [2412], '(8)': [2415], 'treated': [2421], 'lysozome': [2423], 'DNase': [2428], '(125': [2429], 'units': [2430], 'min': [2434, 2680], 'on': [2435, 2757, 3397, 3942, 4337, 4351], 'ice': [2436], 'after': [2437], 'first': [2439, 3273, 3357], 'process.': [2441], 'total': [2443, 2652, 2697, 2797, 2813], 'concentrations': [2445], 'crude': [2448, 2472], 'cell': [2449, 2473, 2674, 2691], 'extracts': [2450, 2675, 2692], 'kit,': [2458, 2751], 'serum': [2461], 'albumin': [2462], 'according': [2466, 3679], "supplier's": [2469], 'instructions.': [2470], 'lysates': [2474], '(isolated': [2475], 'fractions)': [2477], 'assays,': [2483], 'kinetics': [2485, 2883, 2934], 'determination,': [2486], 'immunoblot': [2488, 2818], 'analysis.': [2489], 'Fucosyltransferase': [2490], 'Assay—FucT': [2491], 'assays': [2492], '25Gosselin': [2546], 'Bioorg.': [2550], 'Med.': [2551], '4:': [2554], '2023-2028Crossref': [2555], '(21)': [2558], 'preparation': [2563], 'E.': [2566], 'pGEM': [2571], 'negative': [2577, 3940], 'control.': [2578], 'type': [2587, 3552, 4314], '(WT)': [2588], 'assayed': [2593], '1.8': [2598], '7.5': [2604], '200': [2609, 2899], 'μm.': [2610], '(∼60,000': [2612], 'dpm)': [2613], 'each': [2617], 'reaction.': [2618], 'One': [2619], 'milliunit': [2620, 2660, 3714, 3724], 'represents': [2621], 'amount': [2623], 'converts': [2627], 'nmol': [2629], 'product': [2635], 'per': [2636], 'min.': [2637], 'specific': [2639, 2867], '(milliunit': [2641, 2869, 3677], 'mg–1)': [2642, 2870, 3678], 'dividing': [2646, 2865], '(milliunit)': [2650], 'concentration.': [2654], 'Specific': [2655], 'below': [2658], '0.01': [2659], 'mg–1': [2661], 'considered': [2663], 'undetectable.': [2664], 'Immunoblot': [2665], 'Analysis': [2666], 'Native': [2668, 3372], 'Expression—': [2672], 'Crude': [2673], 'boiled': [2677], '5': [2679], '4%': [2682], 'SDS': [2684], '0.002%': [2686], 'bromphenol': [2688], 'blue.': [2689], 'equal': [2694], 'amounts': [2695], '(7.35': [2699], 'μg)': [2700], 'separated': [2702], 'SDS-PAGE,': [2704], 'electrically': [2709], 'transferred': [2710], 'nitrocellulose': [2712, 2719], '(pore': [2714], 'size,': [2715], '0.22': [2716], 'μm).': [2717], 'blots': [2720, 2745], 'probed': [2722], 'primary': [2724], '(mouse': [2726], 'anti-penta-histidine': [2727], 'antibody)': [2729], '1:1000': [2731], 'dilution': [2732], 'secondary': [2734], '(horseradish': [2736], 'antimouse': [2739], 'IgG)': [2740], '1:2000': [2742], 'dilution.': [2743], 'developed': [2747], 'images': [2754], 'visualized': [2756], 'films.': [2760], 'band': [2763, 2788], 'densities': [2764, 2789], 'quantified': [2768], 'Alpha': [2770], 'Ease': [2771], 'FC': [2772], 'software': [2773, 2977, 3029], '(Alpha': [2774], 'Innotech': [2775], 'Corporation,': [2776], 'San': [2777, 2981], 'Leandro,': [2778], 'CA).': [2779, 2983], 'curve': [2782], 'points': [2785], 'quantifying': [2786], 'WT': [2793, 2805, 3412, 3437, 3447, 3450, 3687, 3864, 3916, 4067, 4141, 4164, 4280], 'sample': [2795], '1.84': [2800], '18.4': [2802], 'μg.': [2803], 'samples,': [2809], '7.35': [2810], 'loaded': [2816], 'analysis,': [2819], 'middle': [2824], 'linear': [2827], 'range': [2828], '(data': [2829], 'shown).': [2831], 'set': [2838], '1,': [2840], 'UA948FucT.': [2856, 3473], 'mutants': [2861], 'normalized': [2863, 3672], 'FucT.': [2878, 3975], 'Determination': [2879], 'Kinetic': [2881, 3434, 3443], 'Parameters—Acceptor': [2882], '0.03–2': [2887], '0.4–25': [2892], 'μm': [2900, 2939], '[3H]GDP-fucose.': [2902, 2954], 'highest': [2910], 'concentration': [2911], 'current': [2918], 'its': [2922, 3734, 3925, 4073, 4080, 4085, 4132], 'solubility.': [2924], 'limited': [2928], 'supply': [2929], 'acceptors,': [2932], '3–200': [2938], '15': [2951], 'kinetic': [2956, 3548, 4276, 4305, 4310, 4401, 4414, 4427, 4442], 'parameters': [2957, 3444, 3549, 4277, 4311, 4402, 4415, 4428, 4443], 'fitting': [2961], 'initial': [2963], 'rate': [2964], 'Michaelis-Menten': [2968], 'equation': [2969], 'nonlinear': [2971], 'regression': [2972], 'analysis': [2973], 'Prism': [2975], '2.0': [2976], '(GraphPad': [2978], 'Software,': [2979], 'Diego,': [2982], 'Sequence': [2984], 'Alignment': [2985], 'FucTs—Seven': [2989], 'five': [2993, 3348], 'strains,': [2997], '11639,': [2998], 'UA948,': [2999], '11637,': [3000], '26695,': [3001], 'J99': [3003, 3162, 3219], '(Fig.': [3004, 3344, 3401, 3417, 3705, 3835, 4143], '1),': [3005], 'aligned': [3007], 'ClustalW': [3009], '(26Thompson': [3010], 'J.D.': [3011], 'Higgins': [3012], 'D.G.': [3013], 'Nucleic': [3016], 'Acids': [3017], 'Res.': [3018], '1994;': [3019], '22:': [3020], '4673-4680Crossref': [3021], '(56002)': [3024], 'LaserGene99': [3028], '(DNAStar': [3030], 'Inc.,': [3031], 'Madison,': [3032], 'like': [3042], 'over': [3050], 'well': [3080], '11637FucTb': [3082], '27Martin': [3111], 'S.L.': [3112, 3173], 'Edbrooke': [3113], 'M.R.': [3114], 'Hodgman': [3115], 'T.C.': [3116], 'van': [3117, 3186], 'den': [3118, 3187], 'Eijnden': [3119, 3188], 'D.H.': [3120, 3189], 'Bird': [3121], 'M.I.': [3122], '21349-21356Abstract': [3128], '(108)': [3136], 'There': [3139, 3322], 'experimental': [3142], '26695FucTa,': [3151], '26695FucTb,': [3152], 'J99FucTa,': [3153], 'J99FucTb.': [3155], '26695': [3160, 3217], '(28Appelmelk': [3170], 'Martin': [3172], 'Monteiro': [3174], 'C.A.': [3177], 'McColm': [3178], 'A.A.': [3179], 'P.': [3181], 'Verboom': [3182], 'Maaskant': [3184], 'J.J.': [3185], 'Hokke': [3190], 'C.H.': [3191], 'Vandenbroucke-Grauls': [3194], 'C.M.': [3195], 'Kusters': [3196], 'J.G.': [3197], '67:': [3201], '5361-5366Crossref': [3202], 'structures,': [3213], 'expected': [3221, 3376, 3395], 'only.': [3226], 'Whether': [3227], 'encoded': [3235], 'remains': [3245], 'determined.': [3248], 'Three': [3249], 'regions': [3250, 3663], 'evident': [3256], 'alignment': [3259], '(displayed': [3265], 'boxed': [3267], 'areas': [3268, 3640], 'Fig.': [3270, 3642, 3694], '1).': [3271, 3345], 'located': [3277, 4174], '13': [3284], '41': [3286], '(11639FucT': [3287], 'numbering).': [3288], 'resides': [3292], 'immediately': [3293], 'upstream': [3294], 'repeats,': [3298], 'most': [3300], 'divergence': [3303], 'caused': [3304], 'unique': [3307], '26695FucTa.': [3312], 'third': [3314], 'repeats.': [3321], 'D(D/N)LR(V/I)NY': [3333], 'all': [3336, 4018, 4035, 4078], 'listed': [3339], 'except': [3341, 3528], 'consensus': [3353], 'sequence,': [3354], 'DDLRRDH.': [3369], 'FucTs—The': [3375], 'molecular': [3377], 'masses': [3378], '56.0': [3384], '54.6,': [3386], 'kDa,': [3387], 'respectively,': [3388], 'migrate': [3392], 'locations': [3396], 'SDS-PAGE': [3399], 'gel': [3400], '2).': [3402, 3836], 'similar': [3409, 3490, 3956], '2),': [3418], 'indicating': [3419, 3870], 'did': [3424], 'cause': [3426], 'significant': [3427], 'changes': [3428], 'levels.': [3433, 4016], 'Parameters': [3435, 4273], 'without': [3441, 3558, 3866, 4036, 4083], 'His6Tag—': [3442], 'His6-tagged': [3449], 'shown': [3453, 4290], 'Table': [3455, 4292], 'I.': [3456, 3485], 'Km': [3458, 3479, 3492, 3504, 3516, 3539], '0.37': [3466], '4-fold': [3468], 'lower': [3469, 3478, 3502, 3718, 4137], 'than': [3470, 3483, 3719, 4138, 4241], '7-fold': [3477], 'values': [3493, 3517], 'acceptor.': [3497, 3512], 'slightly': [3501, 3537], 'when': [3505], 'Acceptor': [3513], 'affected': [3520], 'addition': [3523], 'His6': [3526, 3533, 3561, 4321], 'tag,': [3527], 'tag': [3534, 4322], 'higher': [3538, 4238], 'acceptor.Table': [3543], 'IThe': [3544], 'tagFucT': [3562], 'constructsKmKm': [3563], 'GDP-fucoseType': [3565], 'II-RaGalβ1,4GlcNAc-O(CH2)8CO2CH3.Type': [3566], 'I-RbGalβ1,3GlcNAc-O(CH2)8CO2CH3.With': [3567], 'II-RaGalβ1,4GlcNAc-O(CH2)8CO2CH3.With': [3569], 'I-RbGalβ1,3GlcNAc-O(CH2)8CO2CH3.mMμM116390.31': [3571], '±': [3572, 3575, 3578, 3581, 3584, 3586, 3588, 3590, 3592, 3594, 3596, 3598, 4365, 4367, 4372, 4375, 4377, 4379, 4381, 4383, 4385, 4388, 4390, 4431, 4447, 4449, 4451, 4453, 4455, 4457, 4459], '0.06NAcNot': [3573], 'applicable.48.0': [3574], '8.6NAcNot': [3576], 'applicable.11639-C-His60.37': [3577], '0.03NAcNot': [3579], 'applicable.44.7': [3580, 4371], '5.5NAcNot': [3582], 'applicable.UA9481.2': [3583], '0.28.4': [3585], '1.168.3': [3587], '8.335.7': [3589], '7.9UA948-C-His61.5': [3591], '0.213.4': [3593], '1.456.0': [3595], '10.133.7': [3597, 4384], '7.8a': [3599], 'Galβ1,4GlcNAc-O(CH2)8CO2CH3.b': [3600], 'Galβ1,3GlcNAc-O(CH2)8CO2CH3.c': [3601], 'Not': [3602], 'applicable.': [3603], 'Open': [3604], 'table': [3605], 'new': [3608], 'tab': [3609], 'Enzyme': [3610], 'Activity': [3611], 'Substrate': [3613], 'Specificity': [3614], 'FucTs—Twelve': [3617], '(Fig': [3620], '3A)': [3621], 'peptide': [3623], 'fragments': [3624], 'parental': [3627, 3646], 'constructed.': [3630], 'exchange': [3632, 3658, 3967], 'segments': [3638, 3840], '(boxed': [3639], '1)': [3643], 'major': [3650], 'focus': [3651], 'swapping.': [3654], 'comparatively': [3660], 'included.': [3670], 'given': [3692], '3B.': [3695], 'α1,4/α1,3': [3699, 3918, 4133, 4165, 4190, 4239], 'ratio': [3701, 3920, 4134, 4191, 4240], '(%)': [3702], 'calculated': [3704], '3B).': [3706], '16.3': [3713], 'mg–1,': [3715], '(23.8': [3723], 'mg–1).': [3725], 'one-third': [3732], 'activity.': [3736, 3786, 3857, 3908, 4040, 4052, 4070, 4087, 4102], 'Constructs': [3737], '116391–110UA948111–462,': [3738], '116391–158UA948157–462,': [3739], '116391–296UA948295–462': [3741], 'activities.': [3758], 'counterparts,': [3762], 'constructs': [3763, 4283], 'UA9481–11011639111–478,': [3764], 'UA9481–15611639159–478,': [3765], 'UA9481–29411639297–478,': [3767], 'little': [3782], 'Therefore,': [3787, 4041], 'FucTs.': [3805], 'determines': [3818, 4095], 'UA9481–15611639159–478': [3821], 'UA9481–29411639297–478': [3823], 'very': [3825], 'stably': [3833], 'Apparently': [3837], 'chimeras': [3843, 4020], 'fully': [3846], 'compatible': [3847], 'these': [3849], 'cases,': [3850], 'Mutant': [3858], '116391–359UA948361–462': [3859, 4298], 'gaining': [3867], 'cannot': [3878], 'confer': [3879, 3998, 4050], 'supported': [3887], 'those': [3897, 3972, 4025], '(construct': [3900], 'UA9481–36011639360–478),': [3901], 'failed': [3903], 'abolish': [3905], 'However,': [3909, 4215], 'chimera': [3911, 4062, 4233, 4242], 'UA9481–36011639360–478': [3912], 'nearly': [3915], '(24%': [3921], 'versus': [3922], '31%),': [3923], 'low.': [3931], 'Apparently,': [3932], 'impact': [3941], 'catalysis': [3943], 'domain,': [3948], 'affecting': [3949], 'extent.': [3957], 'tolerate': [3965], 'Mosaic': [3976], 'construct': [3977, 4004], '116391–110UA948111–29411639297–478': [3978], 'normal': [3980], 'demonstrating': [3987], '(110–294)': [3992], 'unable': [3996], 'either.': [4001], '116391–158UA948157–36011639360–478': [4005], 'Comparing': [4017], 'becomes': [4022], 'obvious': [4023], '295–361': [4028], 'lack': [4038], 'likely': [4044], 'segment': [4049, 4054], '(295–361)': [4055], 'includes': [4056], 'region.': [4060], 'Remarkably,': [4061], '11639347CNDAHYSALH': [4063], 'gained': [4064, 4125], '11%': [4065], 'counterpart': [4074], 'UA948345DNPFIFC': [4075, 4288], 'lost': [4076], 'almost': [4077], 'losing': [4084], 'suggests': [4089, 4202], 'absence': [4097], 'presence': [4099], '345CNDAHYSALH354': [4108], 'essential': [4112], 'It': [4119], 'should': [4120], 'noted': [4122], '11639347CNDAHYNALH': [4124], 'relatively': [4126], '3B),': [4144], 'suggesting': [4145, 4167], 'some': [4147], 'other': [4148], 'may': [4150], 'contribute': [4152], 'UA9481–36011639360–478,': [4157, 4285], '116391–296UA948295–462,': [4160], 'near': [4163], 'ratio,': [4166], 'additional': [4169, 4205, 4267], 'prior': [4179], '296.': [4182], 'Chimera': [4183], '116391–110UA948111–462': [4184], '2-fold': [4187], 'drop': [4188], 'does': [4193], 'deteriorate': [4195], '116391–158UA948157–462': [4199, 4234], 'construct.': [4200], 'reside': [4209], '110': [4213], 'residues.': [4214], 'moment': [4218], 'we': [4219], 'yet': [4222], 'want': [4223], 'rule': [4225], 'out': [4226], '158–296': [4231], 'noticeably': [4237], '116391–296UA948295–462.': [4243], 'crucial': [4253], 'more': [4258, 4270], 'detailed': [4259], 'studies': [4260], 'will': [4261], 'needed': [4263], 'delineate': [4265], 'precisely.': [4271], 'Kinetics': [4272], 'Mutants—The': [4275], '116391–359UA948361–462,': [4284], '11639347CNDAHYNALH,': [4286], 'II.': [4293], 'too': [4300, 4396, 4409, 4422, 4437], 'obtain': [4303], 'reliable': [4304], 'parameters.Table': [4306], 'IIAcceptor': [4307], 'FucTsWT/mutantsaAll': [4317], 'possessed': [4319], 'C-terminal.Type': [4325], 'II-RbGalβ1,': [4326, 4360], '4GlcNAc-O(CH2)8CO2CH3.Type': [4327, 4361], 'I-RcGalβ1,': [4328], '3GlcNAc-O(CH2)8CO2CH3.Km': [4329], 'GDP-fucoseKmVmaxdVmax': [4331], '(milliunits': [4332, 4346], 'mg-1)': [4333, 4347], 'standardized': [4335, 4349], 'based': [4336, 4350], 'detected': [4340, 4354], 'Western': [4342, 4356], 'blot.Vmax/KmeMilliunits': [4343, 4357], 'mg-1': [4344, 4358, 4363], 'mM-1.KmVmaxdVmax': [4345], 'mM-1.Type': [4359], 'I-ReMilliunits': [4362], 'mM-1.mMmMμM116390.37': [4364], '0.0311.8': [4366], '0.331.9NAfNot': [4368], 'applicable.NAfNot': [4369, 4370], '5.5NAfNot': [4373], 'applicable.UA9481.5': [4374], '0.229.0': [4376], '1.819.313.4': [4378], '1.411.7': [4380], '0.60.8756.0': [4382], '7.8116391-359': [4386], 'UA948361-4620.7': [4387], '0.141.6': [4389], '0.0148.5NDgNot': [4391], 'determined;': [4392, 4405, 4418, 4433], 'confidence.NDgNot': [4404, 4417], 'confidence.153': [4430], '8NDgNot': [4432], 'confidence.UA9481-360': [4445], '11639360-4781.3': [4446], '0.24.1': [4448], '0.33.19.7': [4450], '1.71.1': [4452], '0.080.11236': [4454], '47188': [4456], '2011639347CNDAHYSALH2.2': [4458], '0.': [4460]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2013900787', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-13T13:13:58.045847', 'created_date': '2016-06-24'}