Publication Information

{'id': 'https://openalex.org/W2013772247', 'doi': 'https://doi.org/10.2174/157339631002140513101950', 'title': 'Renal Development: A Complex Process Dependent on Inductive Interaction', 'display_name': 'Renal Development: A Complex Process Dependent on Inductive Interaction', 'publication_year': 2014, 'publication_date': '2014-05-16', 'ids': {'openalex': 'https://openalex.org/W2013772247', 'doi': 'https://doi.org/10.2174/157339631002140513101950', 'mag': '2013772247', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25088264'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.2174/157339631002140513101950', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S61482747', 'display_name': 'Current Pediatric Reviews', 'issn_l': '1573-3963', 'issn': ['1573-3963', '1875-6336'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320079', 'host_organization_name': 'Bentham Science Publishers', 'host_organization_lineage': ['https://openalex.org/P4310320079'], 'host_organization_lineage_names': ['Bentham Science Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5010108327', 'display_name': 'Kiran Upadhyay', 'orcid': 'https://orcid.org/0000-0002-8441-0220'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kiran Upadhyay', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113556798', 'display_name': 'Douglas M. Silverstein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1335686170', 'display_name': 'Center for Devices and Radiological Health', 'ror': 'https://ror.org/007x9se63', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1335686170']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Douglas Silverstein', 'raw_affiliation_strings': ['The United States Food and Drug Administration, Office of Device Evaluation, Center for Devices and Radiological Health, Renal Devices Branch, Silver Spring, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'The United States Food and Drug Administration, Office of Device Evaluation, Center for Devices and Radiological Health, Renal Devices Branch, Silver Spring, Maryland, USA.', 'institution_ids': ['https://openalex.org/I1335686170']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.19, 'has_fulltext': False, 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.197436, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '10', 'issue': '2', 'first_page': '107', 'last_page': '114'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 0.9912, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 0.9912, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11815', 'display_name': 'Urological Disorders and Treatments', 'score': 0.9547, 'subfield': {'id': 'https://openalex.org/subfields/2748', 'display_name': 'Urology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mesonephric-duct', 'display_name': 'Mesonephric duct', 'score': 0.90997726}, {'id': 'https://openalex.org/keywords/ureteric-bud', 'display_name': 'Ureteric bud', 'score': 0.83630264}, {'id': 'https://openalex.org/keywords/mesonephros', 'display_name': 'Mesonephros', 'score': 0.7947135}, {'id': 'https://openalex.org/keywords/pronephros', 'display_name': 'Pronephros', 'score': 0.64275575}, {'id': 'https://openalex.org/keywords/intermediate-mesoderm', 'display_name': 'Intermediate mesoderm', 'score': 0.62857884}, {'id': 'https://openalex.org/keywords/blastema', 'display_name': 'Blastema', 'score': 0.5822438}], 'concepts': [{'id': 'https://openalex.org/C85380620', 'wikidata': 'https://www.wikidata.org/wiki/Q583232', 'display_name': 'Mesonephric duct', 'level': 3, 'score': 0.90997726}, {'id': 'https://openalex.org/C130010870', 'wikidata': 'https://www.wikidata.org/wiki/Q2500532', 'display_name': 'Ureteric bud', 'level': 5, 'score': 0.83630264}, {'id': 'https://openalex.org/C43768951', 'wikidata': 'https://www.wikidata.org/wiki/Q1468875', 'display_name': 'Mesonephros', 'level': 4, 'score': 0.7947135}, {'id': 'https://openalex.org/C2777632694', 'wikidata': 'https://www.wikidata.org/wiki/Q2336077', 'display_name': 'Kidney development', 'level': 4, 'score': 0.7571423}, {'id': 'https://openalex.org/C31697123', 'wikidata': 'https://www.wikidata.org/wiki/Q2656768', 'display_name': 'Pronephros', 'level': 4, 'score': 0.64275575}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.6299567}, {'id': 'https://openalex.org/C182928434', 'wikidata': 'https://www.wikidata.org/wiki/Q6047369', 'display_name': 'Intermediate mesoderm', 'level': 5, 'score': 0.62857884}, {'id': 'https://openalex.org/C78214289', 'wikidata': 'https://www.wikidata.org/wiki/Q882043', 'display_name': 'Blastema', 'level': 3, 'score': 0.5822438}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.52783304}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.49346128}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.46697733}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3731392}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.35257375}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.34781808}, {'id': 'https://openalex.org/C171056886', 'wikidata': 'https://www.wikidata.org/wiki/Q193119', 'display_name': 'Regeneration (biology)', 'level': 2, 'score': 0.20929113}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.20165455}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.12158835}, {'id': 'https://openalex.org/C2776878037', 'wikidata': 'https://www.wikidata.org/wiki/Q169444', 'display_name': 'Zebrafish', 'level': 3, 'score': 0.06170875}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.060997903}, {'id': 'https://openalex.org/C129536746', 'wikidata': 'https://www.wikidata.org/wiki/Q1141026', 'display_name': 'Gastrulation', 'level': 4, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007685', 'descriptor_name': 'Kidney Tubules, Collecting', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D008650', 'descriptor_name': 'Mesonephros', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D060910', 'descriptor_name': 'Pronephros', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D012084', 'descriptor_name': 'Renin-Angiotensin System', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D014551', 'descriptor_name': 'Urinary Tract', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D014566', 'descriptor_name': 'Urogenital System', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005109', 'descriptor_name': 'Extracellular Matrix', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018507', 'descriptor_name': 'Gene Expression Regulation, Developmental', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D018507', 'descriptor_name': 'Gene Expression Regulation, Developmental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007685', 'descriptor_name': 'Kidney Tubules, Collecting', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D007685', 'descriptor_name': 'Kidney Tubules, Collecting', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D007685', 'descriptor_name': 'Kidney Tubules, Collecting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008650', 'descriptor_name': 'Mesonephros', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D008650', 'descriptor_name': 'Mesonephros', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D008650', 'descriptor_name': 'Mesonephros', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060910', 'descriptor_name': 'Pronephros', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D060910', 'descriptor_name': 'Pronephros', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D060910', 'descriptor_name': 'Pronephros', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012084', 'descriptor_name': 'Renin-Angiotensin System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014551', 'descriptor_name': 'Urinary Tract', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D014551', 'descriptor_name': 'Urinary Tract', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014566', 'descriptor_name': 'Urogenital System', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D014566', 'descriptor_name': 'Urogenital System', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D014566', 'descriptor_name': 'Urogenital System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.2174/157339631002140513101950', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S61482747', 'display_name': 'Current Pediatric Reviews', 'issn_l': '1573-3963', 'issn': ['1573-3963', '1875-6336'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320079', 'host_organization_name': 'Bentham Science Publishers', 'host_organization_lineage': ['https://openalex.org/P4310320079'], 'host_organization_lineage_names': ['Bentham Science Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25088264', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.53}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4230665874', 'https://openalex.org/W4211042722', 'https://openalex.org/W4210484175', 'https://openalex.org/W2089638303', 'https://openalex.org/W2020422405', 'https://openalex.org/W2013772247', 'https://openalex.org/W2010933080', 'https://openalex.org/W1993569751', 'https://openalex.org/W1588694582', 'https://openalex.org/W104505296'], 'abstract_inverted_index': {'Renal': [0], 'development': [1, 214], 'begins': [2], 'in-utero': [3, 29], 'and': [4, 34, 58, 83, 117, 120, 133, 163, 188, 229], 'continues': [5], 'throughout': [6], 'childhood.': [7], 'Almost': [8], 'one-third': [9], 'of': [10, 19, 28, 39, 46, 73, 91, 107, 138, 148, 219], 'all': [11, 137], 'developmental': [12], 'anomalies': [13], 'include': [14], 'structural': [15], 'or': [16, 224], 'functional': [17], 'abnormalities': [18], 'the': [20, 52, 60, 64, 71, 74, 80, 84, 105, 115, 121, 125, 130, 139, 151, 157, 172, 175, 191, 207, 217], 'urinary': [21, 153], 'tract.': [22], 'There': [23], 'are': [24, 141, 190, 232], 'three': [25, 37], 'main': [26], 'phases': [27], 'renal': [30, 131, 196, 213, 236], 'development:': [31], 'Pronephros,': [32], 'Mesonephros': [33], 'Metanephros.': [35], 'Within': [36], 'weeks': [38, 90, 147], 'gestation,': [40], 'paired': [41], 'pronephri': [42], 'appear.': [43], 'A': [44], 'series': [45], 'tubules': [47, 123, 132], 'called': [48], 'nephrotomes': [49], 'fuse': [50], 'with': [51], 'pronephric': [53], 'duct.': [54, 67, 165], 'The': [55, 68, 93, 111], 'pronephros': [56], 'elongates': [57], 'induces': [59], 'nearby': [61], 'mesoderm,': [62], 'forming': [63], 'mesonephric': [65, 164], '(Woffian)': [66], 'metanephros': [69], 'is': [70, 99], 'precursor': [72], 'mature': [75, 109], 'kidney': [76, 173], 'that': [77, 205], 'originates': [78], 'from': [79, 156, 171], 'ureteric': [81, 112, 161], 'bud': [82, 113, 162], 'metanephric': [85], 'mesoderm': [86], '(blastema)': [87], 'by': [88, 143, 215], '5': [89], 'gestation.': [92, 149], 'interaction': [94], 'between': [95], 'these': [96], 'two': [97], 'components': [98], 'a': [100, 108], 'reciprocal': [101], 'process,': [102], 'resulting': [103], 'in': [104, 194], 'formation': [106], 'kidney.': [110], 'forms': [114], 'major': [116], 'minor': [118], 'calyces,': [119], 'collecting': [122], 'while': [124], 'metanephrogenic': [126], 'blastema': [127], 'develops': [128, 155], 'into': [129], 'glomeruli.': [134], 'In': [135, 166], 'humans,': [136], 'nephrons': [140], 'formed': [142], '32': [144], 'to': [145, 174], '36': [146], 'Simultaneously,': [150], 'lower': [152], 'tract': [154], 'vesico': [158], 'urethral': [159], 'canal,': [160], 'utero,': [167], 'ureters': [168], 'deliver': [169], 'urine': [170], 'bladder,': [176], 'thereby': [177], 'creating': [178], 'amniotic': [179], 'fluid.': [180], 'Transcription': [181], 'factors,': [182, 221], 'extracellular': [183], 'matrix': [184, 222], 'glycoproteins,': [185], 'signaling': [186], 'molecules': [187], 'receptors': [189], 'key': [192], 'players': [193], 'normal': [195, 235], 'development.': [197, 237], 'Many': [198], 'medications': [199], '(e.g.,': [200], 'aminoglycosides,': [201], 'cyclooxygenase': [202], 'inhibitors,': [203], 'substances': [204], 'affect': [206], 'renin-angiotensin': [208], 'aldosterone': [209], 'system)': [210], 'also': [211], 'impact': [212], 'altering': [216], 'expression': [218], 'growth': [220], 'regulators': [223], 'receptors.': [225], 'Thus,': [226], 'tight': [227], 'regulation': [228], 'coordinated': [230], 'processes': [231], 'crucial': [233], 'for': [234], 'Keywords:': [238], 'Renal,': [239], 'development,': [240], 'induction.': [241]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2013772247', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 5}], 'updated_date': '2025-01-18T20:38:28.089161', 'created_date': '2016-06-24'}