Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2013722500', 'doi': 'https://doi.org/10.1016/j.juro.2013.12.011', 'title': 'DNA Based Therapy with Diphtheria Toxin-A BC-819: A Phase 2b Marker Lesion Trial in Patients with Intermediate Risk Nonmuscle Invasive Bladder Cancer', 'display_name': 'DNA Based Therapy with Diphtheria Toxin-A BC-819: A Phase 2b Marker Lesion Trial in Patients with Intermediate Risk Nonmuscle Invasive Bladder Cancer', 'publication_year': 2014, 'publication_date': '2014-06-01', 'ids': {'openalex': 'https://openalex.org/W2013722500', 'doi': 'https://doi.org/10.1016/j.juro.2013.12.011', 'mag': '2013722500', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24342146'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2013.12.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025973451', 'display_name': 'Ofer N. Gofrit', 'orcid': 'https://orcid.org/0000-0001-8815-6488'}, 'institutions': [{'id': 'https://openalex.org/I2799899409', 'display_name': 'Hadassah Medical Center', 'ror': 'https://ror.org/01cqmqj90', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799899409']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Ofer N. Gofrit', 'raw_affiliation_strings': ['Hadassah Ein-Kerem Medical Center, Jerusalem, Israel'], 'affiliations': [{'raw_affiliation_string': 'Hadassah Ein-Kerem Medical Center, Jerusalem, Israel', 'institution_ids': ['https://openalex.org/I2799899409']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045781800', 'display_name': 'Shalva Benjamin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800717019', 'display_name': 'Wolfson Medical Center', 'ror': 'https://ror.org/04ayype77', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800717019']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Shalva Benjamin', 'raw_affiliation_strings': ['Edith Wolfson Medical Center, Sackler Faculty of Medicine, Holon, Israel'], 'affiliations': [{'raw_affiliation_string': 'Edith Wolfson Medical Center, Sackler Faculty of Medicine, Holon, Israel', 'institution_ids': ['https://openalex.org/I2800717019']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006391689', 'display_name': 'Sarel Halachmi', 'orcid': 'https://orcid.org/0000-0002-8180-8030'}, 'institutions': [{'id': 'https://openalex.org/I4210113309', 'display_name': 'Bnai Zion Medical Center', 'ror': 'https://ror.org/01yvj7247', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210113309']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Sarel Halachmi', 'raw_affiliation_strings': ['Bnai-Zion Medical Center, Haifa, Israel'], 'affiliations': [{'raw_affiliation_string': 'Bnai-Zion Medical Center, Haifa, Israel', 'institution_ids': ['https://openalex.org/I4210113309']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082120708', 'display_name': 'Ilan Leibovitch', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801839060', 'display_name': 'Meir Medical Center', 'ror': 'https://ror.org/04pc7j325', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801839060']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Ilan Leibovitch', 'raw_affiliation_strings': ['Meir Medical Center, Kfar-saba, Israel'], 'affiliations': [{'raw_affiliation_string': 'Meir Medical Center, Kfar-saba, Israel', 'institution_ids': ['https://openalex.org/I2801839060']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067878298', 'display_name': 'Zohar Dotan', 'orcid': 'https://orcid.org/0000-0002-9005-2992'}, 'institutions': [{'id': 'https://openalex.org/I2799810450', 'display_name': 'Sheba Medical Center', 'ror': 'https://ror.org/020rzx487', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799810450']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Zohar Dotan', 'raw_affiliation_strings': [' Sheba Medical Center, Tel Hashomer (Israel)'], 'affiliations': [{'raw_affiliation_string': ' Sheba Medical Center, Tel Hashomer (Israel)', 'institution_ids': ['https://openalex.org/I2799810450']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052301584', 'display_name': 'Donald L. Lamm', 'orcid': 'https://orcid.org/0000-0002-1859-6688'}, 'institutions': [{'id': 'https://openalex.org/I138006243', 'display_name': 'University of Arizona', 'ror': 'https://ror.org/03m2x1q45', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I138006243']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Donald L. Lamm', 'raw_affiliation_strings': ['University of Arizona, Phoenix, Arizona'], 'affiliations': [{'raw_affiliation_string': 'University of Arizona, Phoenix, Arizona', 'institution_ids': ['https://openalex.org/I138006243']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053910308', 'display_name': 'Nahum Ehrlich', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801607793', 'display_name': 'Hillel Yaffe Medical Center', 'ror': 'https://ror.org/01a6tsm75', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801607793']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Nahum Ehrlich', 'raw_affiliation_strings': ['Hillel Yafe Medical Center, Hadera, Israel.'], 'affiliations': [{'raw_affiliation_string': 'Hillel Yafe Medical Center, Hadera, Israel.', 'institution_ids': ['https://openalex.org/I2801607793']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029831792', 'display_name': 'Vladimir Yutkin', 'orcid': 'https://orcid.org/0000-0002-9404-4025'}, 'institutions': [{'id': 'https://openalex.org/I2799899409', 'display_name': 'Hadassah Medical Center', 'ror': 'https://ror.org/01cqmqj90', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799899409']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Vladimir Yutkin', 'raw_affiliation_strings': ['Hadassah Ein-Kerem Medical Center, Jerusalem, Israel'], 'affiliations': [{'raw_affiliation_string': 'Hadassah Ein-Kerem Medical Center, Jerusalem, Israel', 'institution_ids': ['https://openalex.org/I2799899409']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015933270', 'display_name': 'Monique Ben-Am', 'orcid': None}, 'institutions': [], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Monique Ben-Am', 'raw_affiliation_strings': ['BioCancell Ltd., Jerusalem, Israel'], 'affiliations': [{'raw_affiliation_string': 'BioCancell Ltd., Jerusalem, Israel', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5005830467', 'display_name': 'Abraham Hochberg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I197251160', 'display_name': 'Hebrew University of Jerusalem', 'ror': 'https://ror.org/03qxff017', 'country_code': 'IL', 'type': 'education', 'lineage': ['https://openalex.org/I197251160']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Abraham Hochberg', 'raw_affiliation_strings': ['Hebrew University , Jerusalem, Israel'], 'affiliations': [{'raw_affiliation_string': 'Hebrew University , Jerusalem, Israel', 'institution_ids': ['https://openalex.org/I197251160']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.979, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 95, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '191', 'issue': '6', 'first_page': '1697', 'last_page': '1702'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetic Modifications and Their Functional Implications', 'score': 0.9926, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetic Modifications and Their Functional Implications', 'score': 0.9926, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10458', 'display_name': 'Diagnosis and Treatment of Bladder Cancer', 'score': 0.9884, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10336', 'display_name': 'Cancer Stem Cells and Tumor Metastasis', 'score': 0.9559, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bladder-cancer', 'display_name': 'Bladder Cancer', 'score': 0.499748}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.92078435}, {'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.5891812}, {'id': 'https://openalex.org/C2781156865', 'wikidata': 'https://www.wikidata.org/wiki/Q827023', 'display_name': 'Lesion', 'level': 2, 'score': 0.5664573}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.49983692}, {'id': 'https://openalex.org/C126894567', 'wikidata': 'https://www.wikidata.org/wiki/Q105650', 'display_name': 'Urology', 'level': 1, 'score': 0.4970024}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.42229477}, {'id': 'https://openalex.org/C111599444', 'wikidata': 'https://www.wikidata.org/wiki/Q213901', 'display_name': 'Genetic enhancement', 'level': 3, 'score': 0.4183423}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4080192}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.39921954}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.37947696}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08572218}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004167', 'descriptor_name': 'Diphtheria Toxin', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D015316', 'descriptor_name': 'Genetic Therapy', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D010446', 'descriptor_name': 'Peptide Fragments', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000283', 'descriptor_name': 'Administration, Intravesical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002295', 'descriptor_name': 'Carcinoma, Transitional Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004167', 'descriptor_name': 'Diphtheria Toxin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004334', 'descriptor_name': 'Drug Administration Schedule', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015316', 'descriptor_name': 'Genetic Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010446', 'descriptor_name': 'Peptide Fragments', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011446', 'descriptor_name': 'Prospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001749', 'descriptor_name': 'Urinary Bladder Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2013.12.011', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24342146', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 16, 'referenced_works': ['https://openalex.org/W2002045993', 'https://openalex.org/W2003811964', 'https://openalex.org/W2016384772', 'https://openalex.org/W2029409133', 'https://openalex.org/W2049536473', 'https://openalex.org/W2051423607', 'https://openalex.org/W2051953175', 'https://openalex.org/W2055380862', 'https://openalex.org/W2062883746', 'https://openalex.org/W2064352891', 'https://openalex.org/W2115140194', 'https://openalex.org/W2149673968', 'https://openalex.org/W2150936111', 'https://openalex.org/W2165948908', 'https://openalex.org/W2170952907', 'https://openalex.org/W2471757884'], 'related_works': ['https://openalex.org/W4237262135', 'https://openalex.org/W3127976301', 'https://openalex.org/W2944005863', 'https://openalex.org/W2943930186', 'https://openalex.org/W2898558914', 'https://openalex.org/W2461748971', 'https://openalex.org/W2377161363', 'https://openalex.org/W2160411124', 'https://openalex.org/W2017438361', 'https://openalex.org/W1522132782'], 'abstract_inverted_index': {'No': [0], 'AccessJournal': [1], 'of': [2, 84, 144, 253, 277, 288, 311, 331, 345, 365, 392, 440, 450, 457, 504, 513, 530, 570, 593, 623, 681, 705, 767, 834, 895, 946], 'UrologyAdult': [3], 'Urology1': [4], 'Jun': [5], '2014DNA': [6], 'Based': [7], 'Therapy': [8], 'with': [9, 21, 67, 196, 217, 314, 473, 755, 880, 992, 1010], 'Diphtheria': [10], 'Toxin-A': [11], 'BC-819:': [12], 'A': [13, 309, 764], 'Phase': [14, 700], '2b': [15, 304], 'Marker': [16, 730], 'Lesion': [17], 'Trial': [18], 'in': [19, 246, 251, 258, 301, 321, 390, 395, 412, 448, 467, 545, 573, 586, 606, 689, 710, 733, 752], 'Patients': [20, 337, 348], 'Intermediate': [22], 'Risk': [23], 'Nonmuscle': [24], 'Invasive': [25], 'Bladder': [26, 828], 'Cancer': [27, 489, 493, 829], 'Ofer': [28, 51, 866], 'N.': [29, 52, 54, 867], 'Gofrit,': [30], 'Shalva': [31, 75, 887], 'Benjamin,': [32], 'Sarel': [33, 94, 904], 'Halachmi,': [34], 'Ilan': [35, 108, 916], 'Leibovitch,': [36], 'Zohar': [37, 123, 929], 'Dotan,': [38], 'Donald': [39, 138, 942], 'L.': [40, 139, 141, 943], 'Lamm,': [41], 'Nahum': [42, 154, 955], 'Ehrlich,': [43], 'Vladimir': [44, 169, 968], 'Yutkin,': [45], 'Monique': [46, 184, 981], 'Ben-Am,': [47], 'and': [48, 204, 250, 286, 296, 307, 379, 394, 453, 547, 590, 631, 669, 750, 804, 819, 824, 860], 'Abraham': [49, 205, 999], 'Hochberg': [50, 207, 1000], 'GofritOfer': [53], 'Gofrit': [55, 868], 'Hadassah': [56, 172, 869, 970], 'Ein-Kerem': [57, 173, 870, 971], 'Medical': [58, 80, 98, 112, 127, 159, 174, 871, 891, 907, 919, 932, 959, 972], 'Center,': [59, 81, 99, 113, 128, 160, 175, 872, 892, 908, 920, 933, 960, 973], 'Jerusalem,': [60, 176, 189, 210, 873, 974, 985, 1003], 'Israel': [61, 87, 101, 116, 131, 162, 177, 190, 211, 874, 898, 910, 923, 936, 962, 975, 986, 1004], 'Financial': [62, 191, 212, 875, 987, 1005], 'interest': [63, 192, 213, 876, 988, 1006], 'and/or': [64, 193, 214, 877, 989, 1007], 'other': [65, 194, 215, 878, 990, 1008], 'relationship': [66, 195, 216, 879, 991, 1009], 'BioCancell.': [68, 197, 218, 881, 993, 1011], 'More': [69, 88, 102, 117, 132, 148, 163, 178, 198, 219, 882, 899, 911, 924, 937, 950, 963, 976, 994, 1012], 'articles': [70, 89, 103, 118, 133, 149, 164, 179, 199, 220, 883, 900, 912, 925, 938, 951, 964, 977, 995, 1013], 'by': [71, 90, 104, 119, 134, 150, 165, 180, 200, 221, 422, 436, 799, 855, 884, 901, 913, 926, 939, 952, 965, 978, 996, 1014], 'this': [72, 91, 105, 120, 135, 151, 166, 181, 201, 222, 885, 902, 914, 927, 940, 953, 966, 979, 997, 1015], 'author': [73, 92, 106, 121, 136, 152, 167, 182, 202, 223, 886, 903, 915, 928, 941, 954, 967, 980, 998, 1016], ',': [74, 93, 107, 122, 137, 153, 168, 183, 203], 'BenjaminShalva': [76], 'Benjamin': [77, 888], 'Edith': [78, 889], 'Wolfson': [79, 890], 'Sackler': [82, 893], 'Faculty': [83, 894], 'Medicine,': [85, 896], 'Holon,': [86, 897], 'HalachmiSarel': [95], 'Halachmi': [96, 905], 'Bnai-Zion': [97, 906], 'Haifa,': [100, 909], 'LeibovitchIlan': [109], 'Leibovitch': [110, 917], 'Meir': [111, 918], 'Kfar': [114, 921], 'Saba,': [115, 922], 'DotanZohar': [124], 'Dotan': [125, 930], 'Sheba': [126, 931], 'Tel': [129, 934], 'Hashomer,': [130, 935], 'LammDonald': [140], 'Lamm': [142, 944], 'University': [143, 945], 'Arizona,': [145, 947], 'Phoenix,': [146, 948], 'Arizona': [147, 949], 'EhrlichNahum': [155], 'Ehrlich': [156, 956], 'Hillel': [157, 957], 'Yafe': [158, 958], 'Hadera,': [161, 961], 'YutkinVladimir': [170], 'Yutkin': [171, 969], 'Ben-AmMonique': [185], 'Ben-Am': [186, 982], 'BioCancell': [187, 983], 'Ltd.,': [188, 984], 'HochbergAbraham': [206], 'Hebrew': [208, 1001], 'University,': [209, 1002], 'View': [224], 'All': [225, 372, 1018], 'Author': [226], 'Informationhttps://doi.org/10.1016/j.juro.2013.12.011AboutFull': [227], 'TextPDF': [228], 'ToolsAdd': [229], 'to': [230, 292, 407, 463, 718], 'favoritesDownload': [231], 'CitationsTrack': [232], 'CitationsPermissionsReprints': [233], 'ShareFacebookLinked': [234], 'InTwitterEmail': [235], 'Abstract': [236], 'Purpose:': [237], 'H19': [238, 279, 339, 531, 542, 565, 588, 645, 664, 682, 711], 'is': [239, 264, 567, 648], 'a': [240, 265, 298, 302, 341, 351, 455, 480, 568], 'paternally': [241], 'imprinted': [242, 564], 'oncofetal': [243, 551, 625, 663], 'gene': [244, 271, 543, 566, 589, 627, 687], 'expressed': [245], 'various': [247], 'embryonic': [248], 'tissues': [249], '85%': [252], 'bladder': [254, 319, 484, 575, 594, 608, 715, 734, 758], 'tumors': [255, 320, 356, 401], 'but': [256, 415], 'suppressed': [257], 'the': [259, 270, 278, 284, 437, 451, 458, 474, 514, 516, 550, 587, 591, 607, 624], 'adult': [260], 'healthy': [261], 'bladder.': [262], 'BC-819': [263, 290, 443, 479, 707], 'DNA': [266, 708], 'plasmid': [267, 709], 'that': [268], 'carries': [269], 'for': [272, 376, 383, 483, 650, 685, 785, 827], 'diphtheria': [273], 'toxin-A': [274], 'under': [275], 'regulation': [276], 'promoter': [280], 'sequence.': [281], 'We': [282], 'assessed': [283], 'efficacy': [285], 'toxicity': [287], 'intravesical': [289, 324, 346, 706], 'instillations': [291, 367], 'prevent': [293], 'tumor': [294, 386, 446, 652], 'recurrence': [295, 408, 464, 572, 749], 'ablate': [297], 'marker': [299, 335, 459, 569, 702], 'lesion': [300, 703, 731], 'phase': [303, 786], 'trial.': [305], 'Materials': [306], 'Methods:': [308], 'total': [310], '47': [312], 'patients': [313, 373, 393, 452, 754, 769], 'recurrent,': [315], 'multiple': [316], 'nonmuscle': [317], 'invasive': [318], 'whom': [322], 'prior': [323], 'therapy': [325, 688], 'had': [326], 'failed': [327], 'underwent': [328], 'transurethral': [329], 'resection': [330], 'all': [332, 413], 'except': [333], '1': [334, 487], 'tumor.': [336], 'expressing': [338, 713], 'received': [340], '6-week': [342], 'induction': [343], 'course': [344], 'BC-819.': [347], 'who': [349], 'achieved': [350, 389], 'complete': [352], 'response': [353, 423], '(absent': [354], 'new': [355, 400, 445], 'at': [357, 402, 425], '3': [358, 362, 369, 403, 426, 525], 'months)': [359, 419], 'were': [360, 374, 381, 398, 430], 'given': [361], 'maintenance': [363], 'courses': [364], '3-weekly': [366], 'every': [368], 'months.': [370, 404, 427], 'Results:': [371], 'evaluable': [375, 382], 'adverse': [377], 'effects': [378], '39': [380], 'efficacy.': [384], 'Complete': [385], 'ablation': [387], 'was': [388, 409, 434, 465], '33%': [391], '64%': [396], 'there': [397], 'no': [399], 'Median': [405], 'time': [406, 462], '11.3': [410], 'months': [411], 'cases': [414], 'significantly': [416], 'longer': [417], '(22.1': [418], 'when': [420], 'analyzed': [421], 'status': [424], 'Adverse': [428], 'events': [429], 'mild.': [431], 'The': [432, 563, 620, 644, 662], 'study': [433, 704], 'limited': [435], 'small': [438], 'number': [439], 'patients.': [441, 469], 'Conclusions:': [442], 'prevented': [444], 'growth': [447], 'two-thirds': [449], 'ablated': [454], 'third': [456], 'lesions.': [460], 'Prolonged': [461], 'observed': [466], 'responding': [468], 'These': [470], 'results': [471], 'along': [472], 'good': [475], 'safety': [476], 'profile': [477], 'make': [478], 'potential': [481], 'medication': [482], 'cancer.': [485, 595, 670, 690], 'References': [486], ':': [488, 501, 526, 540, 562, 584, 603, 619, 643, 661, 679, 699, 729, 747, 781], 'statistics,': [490], '2012.': [491], 'CA': [492], 'J': [494, 554, 635, 692, 721, 739], 'Clin2012;': [495], '62:': [496], '10.': [497], 'Google': [498, 523, 537, 559, 581, 600, 616, 640, 658, 676, 696, 726, 744, 778, 795], 'Scholar': [499, 524, 538, 560, 582, 601, 617, 641, 659, 677, 697, 727, 745, 779, 796], '2': [500], 'European': [502], 'Association': [503, 802, 858], 'Urology': [505], '(EAU).': [506], 'EAU': [507], 'guidelines': [508], 'on': [509], 'non-muscle-invasive': [510], 'urothelial': [511], 'carcinoma': [512, 609], 'bladder,': [515], '2011': [517], 'update.': [518], 'Eur': [519, 596, 774], 'Urol2011;': [520], '59:': [521], '997.': [522], 'Possible': [527], 'physiological': [528], 'role': [529], 'RNA.': [532], 'Mol': [533, 577, 612, 636], 'Carcinog2002;': [534], '35:': [535], '63.': [536], '4': [539], 'Imprinted': [541], 'expression': [544, 605], 'embryogenesis': [546], 'human': [548, 574, 651], 'cancer:': [549], 'connection.': [552], 'Am': [553], 'Med': [555], 'Genet2000;': [556], '91:': [557], '46.': [558], '5': [561], 'early': [571], 'carcinoma.': [576], 'Pathol2000;': [578], '53:': [579], '320.': [580], '6': [583], 'Polymorphisms': [585], 'risk': [592, 762], 'Urol2008;': [597, 722], '54:': [598], '1118.': [599], '7': [602], 'Gene': [604], 'rat': [610], 'model.': [611], 'Carcinog2004;': [613], '41:': [614], '69.': [615], '8': [618], 'increasing': [621], 'complexity': [622], 'h19': [626], 'locus:': [628], 'functional': [629], 'dissection': [630], 'therapeutic': [632], 'intervention.': [633], 'Int': [634, 691], 'Sci2013;': [637], '14:': [638], '4298.': [639], '9': [642], 'non-coding': [646], 'RNA': [647, 665], 'essential': [649], 'growth.': [653], 'PLoS': [654], 'One2007;': [655], '2:': [656], 'e845.': [657], '10': [660], 'connection:': [666], 'hypoxia,': [667], 'p53': [668], 'Biochim': [671], 'Biophys': [672], 'Acta2010;': [673], '1803:': [674], '443.': [675], '11': [678], 'Use': [680], 'regulatory': [683], 'sequences': [684], 'targeted': [686], 'Cancer2002;': [693], '98:': [694], '64.': [695], '12': [698], 'I/II': [701], 'over': [712], 'superficial': [714], 'cancer': [716, 759], 'refractory': [717], 'bacillus': [719], 'Calmette-Guerin.': [720], '180:': [723], '2379.': [724], 'Link,': [725, 743], '13': [728], 'experiments': [732], 'cancer—what': [735], 'have': [736], 'we': [737], 'learned?.': [738], 'Urol2010;': [740], '183:': [741], '1678.': [742], '14': [746], 'Predicting': [748], 'progression': [751], 'individual': [753], 'stage': [756], 'Ta-T1': [757], 'using': [760], 'EORTC': [761, 772], 'tables.': [763], 'combined': [765], 'analysis': [766], '2596': [768], 'from': [770], 'seven': [771], 'trials.': [773, 789], 'Urol2006;': [775], '49:': [776], '466.': [777], '15': [780], 'Optimal': [782], 'two-stage': [783], 'designs': [784], 'II': [787], 'clinical': [788], 'Control': [790], 'Clin': [791], 'Trials1989;': [792], '10:': [793], '1.': [794], '©': [797], '2014': [798, 854], 'American': [800, 856], 'Urological': [801, 857], 'Education': [803, 859], 'Research,': [805, 861], 'Inc.FiguresReferencesRelatedDetailsCited': [806], 'byNazmifar': [807], 'M,': [808], 'Williams': [809], 'C,': [810, 816], 'Naser-Tavakolian': [811], 'A,': [812], 'Heard': [813], 'J,': [814], 'Rosser': [815], 'Theodorescu': [817], 'D': [818], 'Ahdoot': [820], 'M': [821], '(2022)': [822], 'Clinical': [823], 'Preclinical': [825], 'Therapies': [826], 'Following': [830], 'Bacillus': [831], 'Calmette-Guérin': [832], 'FailureJournal': [833], 'Urology,': [835], 'VOL.': [836], '209,': [837], 'NO.': [838], '1,': [839], '(32-48),': [840], 'Online': [841], 'publication': [842], 'date:': [843], '1-Jan-2023.': [844], 'Volume': [845], '191Issue': [846], '6June': [847], '2014Page:': [848], '1697-1702': [849], 'Advertisement': [850, 1019], 'Copyright': [851], '&': [852], 'Permissions©': [853], 'Inc.Keywordscarcinomaurinary': [862], 'bladderplasmidsdiphtheria': [863], 'toxinurotheliumMetricsAuthor': [864], 'Information': [865], 'Expand': [1017], 'PDF': [1020], 'downloadLoading': [1021], '...': [1022]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2013722500', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 17}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 11}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 5}], 'updated_date': '2024-08-15T05:41:40.789635', 'created_date': '2016-06-24'}