Title: Review of articular cartilage collagen research
Abstract: Arthritis & RheumatismVolume 18, Issue 6 p. 553-562 Current CommentFree to Read Review of articular cartilage collagen research Joseph M. Lane MD, Joseph M. Lane MD Assistant Professor Orthopaedic Surgery and Assistant Director Orthopaedic Research, University of Pennsylvania School of Medicine, and Chief, Metabolic Bone Disease Section of the Department of Orthopaedics, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, and the Massachusetts General Hospital, Boston, Massachusetts.Search for more papers by this authorCharles Weiss MD, Charles Weiss MD Instructor, Orthopaedic Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, and the Massachusetts General Hospital, Boston, Massachusetts.Search for more papers by this author Joseph M. Lane MD, Joseph M. Lane MD Assistant Professor Orthopaedic Surgery and Assistant Director Orthopaedic Research, University of Pennsylvania School of Medicine, and Chief, Metabolic Bone Disease Section of the Department of Orthopaedics, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, and the Massachusetts General Hospital, Boston, Massachusetts.Search for more papers by this authorCharles Weiss MD, Charles Weiss MD Instructor, Orthopaedic Surgery, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, and the Massachusetts General Hospital, Boston, Massachusetts.Search for more papers by this author First published: November/December 1975 https://doi.org/10.1002/art.1780180605Citations: 98AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Grant ME, Prockop DJ: The biosynthesis of collagen. N Engl J Med 268: 194–199, 242–249, 291–300, 1972 10.1056/NEJM197201272860406 Web of Science®Google Scholar 2. Treatise on Collagen. Vol. I, Chemistry. Edited by GN. Ramachandran. London, Academic Press, 1967 Google Scholar 3 Miller EJ: A review of biochemical studies on genetically distinct collagens of the skeletal system. Clin Orthop 92: 260–280, 1973 10.1097/00003086-197305000-00024 PubMedWeb of Science®Google Scholar 4 Miller EJ, Matukas VJ: Chick cartilage collagen: a new type of alpha 1 chain not present in bone or skin of the species. Proc Natl Acad Sci 64: 1264–1268, 1969 10.1073/pnas.64.4.1264 CASPubMedWeb of Science®Google Scholar 5 Matthews BF: Composition of articular cartilage in osteoarthritis: changes in collagen/chondroitin-sulfate ratio. Br Med J 2: 660–661, 1953 10.1136/bmj.2.4837.660 CASPubMedWeb of Science®Google Scholar 6 Rosenberg L, Johnson B, Schubert M: Protein polysaccharides from human articular and costal cartilage. J Clin Invest 44: 1647–1656, 1965 10.1172/JCI105271 CASPubMedWeb of Science®Google Scholar 7 Sokoloff L: The Biology of Degenerative Joint Disease. Chicago, The University of Chicago Press, 1969 Google Scholar 8 Maroudas A: Physico-chemical properties of cartilage in light of ion-exchange theory. Biophys J 8: 575–595, 1968 10.1016/S0006-3495(68)86509-9 CASPubMedWeb of Science®Google Scholar 9 Lotke PA, Granda JL: Alterations in the permeability of cartilage by proteolytic enzymes. Arthritis Rheum 15: 302–308, 1972 10.1002/art.1780150312 CASPubMedWeb of Science®Google Scholar 10 Matthews MB: The interaction of collagen and acid mucopolysaccharides: a model for connective tissue. Biochem J 96: 710–716, 1965 10.1042/bj0960710 PubMedWeb of Science®Google Scholar 11 Hamerman D, Schubert M: Diarthrodial joints: an essay. Am J Med 33: 555–590, 1962 10.1016/0002-9343(62)90266-8 CASPubMedWeb of Science®Google Scholar 12 Fry A, Robertson W: Interlocked stresses in cartilage. Nature 215: 53–54, 1967 10.1038/215053a0 CASPubMedWeb of Science®Google Scholar 13 Myers DB, Highton TC, Rayns DG: Acid mucopolysaccharides closely associated with collagen fibrils in normal human synovium. J Ultrastruct Res 28: 203–213, 1969 10.1016/S0022-5320(69)90080-X CASPubMedWeb of Science®Google Scholar 14 Weiss C: An ultrastructural study of aging human articular cartilage. J Bone Joint Surg 53A: 803, 1971 Google Scholar 15 Weiss C: Ultrastructural characteristics of osteoarthritis. Fed Proc 32: 1459–1466, 1973 CASPubMedWeb of Science®Google Scholar 16 Ross R: The connective tissue fiber forming cell, Treatise on Collagen. Vol. 2A, Biology of Collagen. Edited by BS. Gould. London, Academic Press, 1968, pp 1–82 Google Scholar 17 Barnett CH, Cochrane W, Palfrey AJ: Age changes in articular cartilage of rabbits. Ann Rheum Dis 22: 389–400, 1963 10.1136/ard.22.6.389 CASPubMedWeb of Science®Google Scholar 18 Cameron DA, Robinson RA: Electron microscopy of epiphyseal and articular cartilage matrix in the femur of the newborn infant. J Bone Joint Surg 40A: 163–170, 1958 Google Scholar 19 Davies DV, Barnett CH, Cochrane W, et al: Electron microscopy of articular cartilage in the young rabbit. Ann Rheum Dis 21: 11–22, 1962 10.1136/ard.21.1.11 CASPubMedWeb of Science®Google Scholar 20 Martin AVW: An electron microscope study of the cartilaginous matrix in the developing tibia of the fowl. J Embryol Exp Morphol 2: 38–48, 1954 Web of Science®Google Scholar 21 Muir H, Bullough P, Maroudas A: The distribution of collagen in human articular cartilage with some of its physiological implications. J Bone Joint Surg 52B: 554–563, 1970 Google Scholar 22 Ruttner JR, Spyrcher MA: Electron microscopic investigations on aging and osteoarthritic human cartilage. Pathol Microbiol 31: 14–24, 1968 CASPubMedWeb of Science®Google Scholar 23 Silberberg R, Silberberg M, Vogel A, et al: Ultrastructure of articular cartilage of mice of various ages. Am J Anat 109: 251–276, 1961 10.1002/aja.1001090304 CASPubMedWeb of Science®Google Scholar 24 Weiss C, Rosenberg L, Helfet AJ: An ultrastructural study of normal young adult human articular cartilage. J Bone Joint Surg 50A: 663–674, 1968 Google Scholar 25 Weiss C, Mirow S: An ultrastructural study of osteoarthritic changes in the articular cartilage of human knees. J Bone Joint Surg 54A: 954–972, 1972 Google Scholar 26 Zelander T: Ultrastructure of articular cartilage. Z Zellforsch Mikrosk Anat 49: 720–738, 1959 10.1007/BF00342718 CASPubMedWeb of Science®Google Scholar 27 Piez KA, Eigner EA, Lewis MS: The chromatographic separation and amino acid composition of the subunits of several collagen. Biochemistry 2: 58–66, 1963 10.1021/bi00901a012 CASWeb of Science®Google Scholar 28 Nagai Y, Gross J, Piez KA: Disc electrophoresis of collagen components. Ann NY Acad Sci 121: 494–500, 1964 10.1111/j.1749-6632.1964.tb14221.x CASPubMedWeb of Science®Google Scholar 29 Fowler LJ, Bailey AJ: Current concepts of the crosslinking in bone collagen. Clin Orthop 86: 193–206, 1972 PubMedGoogle Scholar 30 Fairweather RB, Tanzer ML, Gallop PM: Aldol-histidine, a new trifunctional collagen crosslink. Biochem Biophys Res Commun 48: 1311–1315, 1972 10.1016/0006-291X(72)90854-6 CASPubMedWeb of Science®Google Scholar 31 Trelstad RL, Kang AH, Igaraski S, et al: Isolation of two distinct collagens from chick cartilage. Biochemistry 9: 4993–4998, 1970 10.1021/bi00827a025 CASPubMedWeb of Science®Google Scholar 32 Miller EJ: Isolation and characterization of a collagen from chick cartilage containing three identical alpha chains. Biochemistry 10: 1652–1659, 1971 10.1021/bi00785a024 CASPubMedWeb of Science®Google Scholar 33 Miller EJ: Collagen crosslinking: Identification of two cyanogen bromide peptides containing sites of intermolecular crosslink formation in cartilage collagen. Biochem Biophys Res Commun 45: 444–451, 1971 10.1016/0006-291X(71)90839-4 CASPubMedWeb of Science®Google Scholar 34 Miller EJ: Isolation and characterization of the cyanogen bromide peptides from the alpha 1 (II) chain of chick cartilaged collagen. Biochemistry 10: 3030–3035, 1971 10.1021/bi00792a007 CASPubMedWeb of Science®Google Scholar 35 Miller EJ, Epstein EH Jr, Piez KA: Identification of three genetically distinct collagens by cyanogen bromide cleavage of insoluble human skin and cartilage collagen. Biochem Biophys Res Commun 42: 1024–1029, 1971 10.1016/0006-291X(71)90006-4 CASPubMedWeb of Science®Google Scholar 36 Miller EJ, Lunde LG: Isolation and characterization of the cyanogen bromide peptides from the alpha 1 (II) chain of bovine and human articular cartilage collagen. Biochemistry 12: 3153–3159, 1973 10.1021/bi00741a003 CASPubMedWeb of Science®Google Scholar 37 Miller EJ, Woodall DL, Vail MS: Biosynthesis of cartilage collagen. Use of pulse labeling to order the cyanogen bromide peptides in the alpha 1 (II) chain. J Biol Chem 248: 1666–1671, 1973 CASPubMedWeb of Science®Google Scholar 38 Stravich E, Nimni ME: Properties of a collagen molecule containing three identical components extracted from bovine articular cartilage. Biochemistry 10: 3905–3911, 1971 10.1021/bi00797a017 PubMedWeb of Science®Google Scholar 39 Miller EJ: Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin. Biochemistry 11: 4903–4909, 1972 10.1021/bi00776a005 CASPubMedWeb of Science®Google Scholar 40 Toole BP, Kang AH, Trelstad RL, et al: Collagen heterogeneity within different growth regions of long bones of rachitic and nonrachitic chicks. Biochem J 127: 715–720, 1972 10.1042/bj1270715 CASPubMedWeb of Science®Google Scholar 41 Trelstad RL, Kang AH, Toole BP, et al: High resolution separation of native (alpha 1 (I))2 alpha 2 and (alpha 1 (II)3 and their component alpha chains. J Biol Chem 247: 6469–6473, 1972 CASPubMedWeb of Science®Google Scholar 42 Miller EJ, Martin GR, Piez KA, et al: Characterization of chick bone collagen and compositional changes associated with maturation. J Biol Chem 242: 5484–5489, 1967 Google Scholar 43 Miller EJ, Lane JM, Piez KA: Isolation and characterization of the peptides derived from the αl chain of chick bone collagen after cyanogen bromide cleavage. Biochemistry 8: 30–39, 1969 10.1021/bi00829a006 CASPubMedWeb of Science®Google Scholar 44 Lane JM, Miller EJ: Isolation and characterization of the peptides derived from the α2 chain of chick bone collagen after cyanogen bromide cleavage. Biochemistry 8: 2134–2139, 1969 10.1021/bi00833a053 CASPubMedWeb of Science®Google Scholar 45 Piez KA, Miller EJ, Lane JM, et al: The order of the CNBr peptides from the αl chain of collagen. Biochem Biophys Res Commun 37: 801–805, 1969 10.1016/0006-291X(69)90962-0 CASPubMedWeb of Science®Google Scholar 46 Vuust J, Lane JM, Fietzek PP, et al: The order of CNBr peptides from the α2 chain of collagen. Biochem Biophys Res Commun 38: 703–708, 1970 10.1016/0006-291X(70)90638-8 CASPubMedWeb of Science®Google Scholar 47 Seyer JM, Vinson WC: Synthesis of type I and type II collagen by embryonic chick cartilage. Biochem Biophys Res Commun 58: 272–279, 1974 10.1016/0006-291X(74)90923-1 CASPubMedWeb of Science®Google Scholar 48 Bailey AJ, Shimokomari MS: Age related changes in the reducible crosslinks of collagen. Fed Eur Biol Soc 16: 86–88, 1971 10.1016/0014-5793(71)80338-1 CASPubMedWeb of Science®Google Scholar 49 Bruns RR, Trelstad RL, Gross J: Cartilage collagen: a staggered substructure in reconstituted fibrils. Science 181: 269–271, 1973 10.1126/science.181.4096.269 CASPubMedWeb of Science®Google Scholar 50 Hunter W: Of the structure and diseases of articulating cartilages. Philos Trans R Soc Lond 42: 514, 1943 10.1098/rstl.1742.0079 Google Scholar 51 Benninghoff A: Form und Bau der Gelenknorpel in ihren Beziehungen zur Funktion. Z Zellforsch Mikrosk Anat 2: 783–862, 1925 10.1007/BF00583443 Google Scholar 52 Little K, Pimm LH, Treuta J: Osteoarthritis of the hip. J Bone Joint Surg 40B: 123–131, 1958 Google Scholar 53 Clark IC: Articular cartilage: a review and scanning electron microscope study. J Bone Joint Surg 53B: 732–750, 1971 Google Scholar 54 McCall JG: Ultrastructure of human articular cartilage. J Anat 104: 586–587, 1969 CASPubMedWeb of Science®Google Scholar 55 Meachim G, Roy S: Surface ultrastructure of mature adult human articular cartilage. J Bone Joint Surg 51B: 529–539, 1969 Google Scholar 56 Silberberg R: Ultrastructure of articular cartilage in health and disease. Clin Orthop 57: 233–257, 1968 CASPubMedWeb of Science®Google Scholar 57 Silberberg R, Silberberg M, Feir D: Life cycle of articular cartilage cells: an electron microscope study of the hip joint of the mouse. Am J Anat 114: 17–47, 1964 10.1002/aja.1001140103 CASPubMedWeb of Science®Google Scholar 58 Mankin HJ, Lippiello L: The turnover of adult rabbit articular cartilage. J Bone Joint Surg 51A: 1591–1600, 1969 10.2106/00004623-196951080-00009 Web of Science®Google Scholar 59 Prockop DJ: The intracellular biosynthesis of collagen: some possible implications for diseases of bone and other connective tissues. Arch Intern Med 124: 563–570, 1969 10.1001/archinte.124.5.563 CASPubMedWeb of Science®Google Scholar 60 Repo RV, Mitchell N: Collagen synthesis in mature articular cartilage of the rabbit. J Bone Joint Surg 55B: 541–548, 1971 Google Scholar 61 Mankin HJ: The articular cartilages: a review, Instructional Course Lectures of the American Academy of Orthopaedic Surgeons. Vol. 19. St. Louis, C.V. Mosby Company, 1970, pp 204–224 Google Scholar 62 Meachim G: Repair of the para-articular bone plate in the rabbit knee. J Anat 113: 359–371, 1972 CASPubMedWeb of Science®Google Scholar 63 Harris ED Jr, Krane SM: Collagenases. N Engl J Med 291: 557–563, 605–609, 652–661, 1974 10.1056/NEJM197409122911105 CASPubMedWeb of Science®Google Scholar 64 Gross J, Nagai Y: Specific degradation of the collagen molecule by tadpole collagenolytic enzyme. Proc Natl Acad Sci 54: 1197–1204, 1965 10.1073/pnas.54.4.1197 CASPubMedWeb of Science®Google Scholar 65 Bruns RR, Gross J: Band pattern of the segment-longspacing form of collagen: its use in the analysis of primary structure. Biochemistry 12: 808–815, 1973 10.1021/bi00729a004 CASPubMedWeb of Science®Google Scholar 66 Harris ED Jr: A collagenolytic system produced by primary cultures of rheumatoid nodule tissue. J Clin Invest 51: 2973–2976, 1972 10.1172/JCI107122 PubMedWeb of Science®Google Scholar 67 Harris ED Jr, Krane SM: An endopeptidase from rheumatoid synovial tissue culture. Biochim Biophys Acta 258: 566–576, 1972 10.1016/0005-2744(72)90249-5 CASPubMedWeb of Science®Google Scholar 68 Harper E, Gross J: Separation of collagenase and peptidase activities of tadpole tissues in culture. Biochim Biophys Acta 198: 286–292, 1970 10.1016/0005-2744(70)90061-6 CASPubMedWeb of Science®Google Scholar 69 Parakkal PF: Role of macrophages in collagen resorption during hair growth. J Ultrastruct Res 29: 210–217, 1969 10.1016/S0022-5320(69)90101-4 PubMedWeb of Science®Google Scholar 70 Brandes D, Anton E: An electron microscopic cytochemical study of macrophages during uterine involution. J Cell Biol 41: 450–461, 1969 10.1083/jcb.41.2.450 CASPubMedWeb of Science®Google Scholar 71 Evanson JM, Jeffrey JJ, Krane SM: Human collagenase: identification and characterization of an enzyme from rheumatoid synovium in culture. Science 158: 499–502, 1967 10.1126/science.158.3800.499 CASPubMedGoogle Scholar 72 Harris ED Jr, Cohen GL, Krane SM: Synovial collagenase: its presence in culture from joint disease of diverse etiology. Arthritis Rheum 12: 92–102, 1969 10.1002/art.1780120206 PubMedWeb of Science®Google Scholar 73 Lazarus GS, Brown RS, Daniels JR, et al: Human granulocyte collagenase. Science 159: 1483–1485, 1968 10.1126/science.159.3822.1483 CASPubMedWeb of Science®Google Scholar 74 Harris ED Jr, Evanson JM, DiBona DR, et al: Collagenase and rheumatoid arthritis. Arthritis Rheum 13: 83–94, 1970 10.1002/art.1780130109 CASPubMedWeb of Science®Google Scholar 75 Robertson PB, Miller EJ: Cartilage collagen: inability to serve as a substrate for collagenase active against skin and bone collagen. Biochim Biophys Acta 289: 247–250, 1972 10.1016/0005-2744(72)90129-5 CASPubMedWeb of Science®Google Scholar 76 Harris ED Jr, McCroskery PA: The influence of temperature and fibril stability on degradation of cartilage collagen by rheumatoid synovial collagenase. N Engl J Med 290: 1–6, 1974 10.1056/NEJM197401032900101 CASPubMedWeb of Science®Google Scholar 77 Dingle JT: The role of lysosomal enzymes in skeletal tissues. J Bone Joint Surg 55B: 87–95, 1973 10.1302/0301-620X.55B1.87 Google Scholar 78 Burleigh MC, Barrett AJ, Lazarus GS: Cathepsin Bl: A lysosomal enzyme that degrades native collagen. Biochem J 137: 387–398, 1974 10.1042/bj1370387 CASPubMedWeb of Science®Google Scholar 79 Bollet AJ, Handy JR, Sturgell BC: Chondroitin sulfate concentration and protein polysaccharide composition of articular cartilage in osteoarthritis. J Clin Invest 42: 853–859, 1963 10.1172/JCI104777 CASPubMedWeb of Science®Google Scholar 80 Mankin HJ, Lippiello L: Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. J Bone Joint Surg 52A: 424–434, 1970 10.2106/00004623-197052030-00002 Google Scholar 81 Collins DH, McElligott TF: Sulphate (35SO4) uptake by chondrocytes in relation to histological changes in osteoarthritic human articular cartilage. Ann Rheum Dis 19: 318–330, 1960 10.1136/ard.19.4.318 CASPubMedWeb of Science®Google Scholar 82 Nimni M, Deshmukh K: Differences in collagen metabolism between normal and osteoarthritic human articular cartilage. Science 181: 751–752, 1973 10.1126/science.181.4101.751 CASPubMedWeb of Science®Google Scholar 83 Hamerman D, Rosenberg LC, Schubert M: Diarthrodial joints revisited. J Bone Joint Surg 52A: 725–774, 1970 Google Scholar 84 Coletti JM Jr, Akeson WH, Woo SLY: A comparison of the physical behavior of normal articular cartilage and the arthroplasty surface. J Bone Joint Surg 54A: 147–160, 1972 Google Scholar 85 Kutby MK, Iqbal QM, Teh EC: Ochronatic arthropathy. Arch Pathol 98: 55–57, 1974 PubMedGoogle Scholar Citing Literature Volume18, Issue6November/December 1975Pages 553-562 ReferencesRelatedInformation