Publication Information

{'id': 'https://openalex.org/W2012998128', 'doi': 'https://doi.org/10.1074/jbc.270.37.21612', 'title': 'Requirement for the Synergy Site for Cell Adhesion to Fibronectin Depends on the Activation State of Integrin α5β1', 'display_name': 'Requirement for the Synergy Site for Cell Adhesion to Fibronectin Depends on the Activation State of Integrin α5β1', 'publication_year': 1995, 'publication_date': '1995-09-01', 'ids': {'openalex': 'https://openalex.org/W2012998128', 'doi': 'https://doi.org/10.1074/jbc.270.37.21612', 'mag': '2012998128', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7545166'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.270.37.21612', 'pdf_url': 'http://www.jbc.org/article/S0021925818902188/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925818902188/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5037747325', 'display_name': 'Erik H.J. Danen', 'orcid': 'https://orcid.org/0000-0002-0491-6345'}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Erik H.J. Danen', 'raw_affiliation_strings': ['Department of Pathology, University Hospital, Nijmegen, The Netherlands.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University Hospital, Nijmegen, The Netherlands.', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111951468', 'display_name': 'Shin-ichi Aota', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Shin-ichi Aota', 'raw_affiliation_strings': ['¶ Laboratory of Developmental Biology, NIDR, National Institutes of Health, Bethesda, Maryland 20892'], 'affiliations': [{'raw_affiliation_string': '¶ Laboratory of Developmental Biology, NIDR, National Institutes of Health, Bethesda, Maryland 20892', 'institution_ids': ['https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060509962', 'display_name': 'Annemieke A. van Kraats', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Annemieke A. van Kraats', 'raw_affiliation_strings': ['Department of Pathology, University Hospital, 6500 HB Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University Hospital, 6500 HB Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052453881', 'display_name': 'Kenneth M. Yamada', 'orcid': 'https://orcid.org/0000-0003-1512-6805'}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kenneth M. Yamada', 'raw_affiliation_strings': ['¶ Laboratory of Developmental Biology, NIDR, National Institutes of Health, Bethesda, Maryland 20892'], 'affiliations': [{'raw_affiliation_string': '¶ Laboratory of Developmental Biology, NIDR, National Institutes of Health, Bethesda, Maryland 20892', 'institution_ids': ['https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110019339', 'display_name': 'Dirk J. Ruiter', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Dirk J. Ruiter', 'raw_affiliation_strings': ['Department of Pathology, University Hospital, 6500 HB Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University Hospital, 6500 HB Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113570980', 'display_name': 'Goos N.P. van Muijen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Goos N.P. van Muijen', 'raw_affiliation_strings': ['Department of Pathology, University Hospital, 6500 HB Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University Hospital, 6500 HB Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 2.667, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 164, 'citation_normalized_percentile': {'value': 0.965397, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '270', 'issue': '37', 'first_page': '21612', 'last_page': '21618'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10379', 'display_name': 'Cellular Mechanics and Interactions', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10620', 'display_name': 'Protease and Inhibitor Mechanisms', 'score': 0.9922, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/k562-cells', 'display_name': 'K562 cells', 'score': 0.5226431}], 'concepts': [{'id': 'https://openalex.org/C86492073', 'wikidata': 'https://www.wikidata.org/wiki/Q413766', 'display_name': 'Fibronectin', 'level': 3, 'score': 0.8373172}, {'id': 'https://openalex.org/C195687474', 'wikidata': 'https://www.wikidata.org/wiki/Q409715', 'display_name': 'Integrin', 'level': 3, 'score': 0.75251895}, {'id': 'https://openalex.org/C84416704', 'wikidata': 'https://www.wikidata.org/wiki/Q188666', 'display_name': 'Adhesion', 'level': 2, 'score': 0.57816976}, {'id': 'https://openalex.org/C85789140', 'wikidata': 'https://www.wikidata.org/wiki/Q187640', 'display_name': 'Cell adhesion', 'level': 3, 'score': 0.56386113}, {'id': 'https://openalex.org/C171122931', 'wikidata': 'https://www.wikidata.org/wiki/Q6324626', 'display_name': 'K562 cells', 'level': 3, 'score': 0.5226431}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5065056}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.37383032}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.37081307}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.31688392}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.18824452}, {'id': 'https://openalex.org/C189165786', 'wikidata': 'https://www.wikidata.org/wiki/Q193825', 'display_name': 'Extracellular matrix', 'level': 2, 'score': 0.18819588}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.18609968}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002448', 'descriptor_name': 'Cell Adhesion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005353', 'descriptor_name': 'Fibronectins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016023', 'descriptor_name': 'Integrins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016023', 'descriptor_name': 'Integrins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016023', 'descriptor_name': 'Integrins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D016023', 'descriptor_name': 'Integrins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004915', 'descriptor_name': 'Leukemia, Erythroblastic, Acute', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017469', 'descriptor_name': 'Receptors, Fibronectin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014407', 'descriptor_name': 'Tumor Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.270.37.21612', 'pdf_url': 'http://www.jbc.org/article/S0021925818902188/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://repository.ubn.ru.nl//bitstream/handle/2066/216431/216431.pdf', 'pdf_url': 'https://repository.ubn.ru.nl//bitstream/handle/2066/216431/216431.pdf', 'source': {'id': 'https://openalex.org/S4306401067', 'display_name': 'Radboud Repository (Radboud University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I145872427', 'host_organization_name': 'Radboud University Nijmegen', 'host_organization_lineage': ['https://openalex.org/I145872427'], 'host_organization_lineage_names': ['Radboud University Nijmegen'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/2066/216431', 'pdf_url': 'https://repository.ubn.ru.nl/bitstream/handle/2066/216431/1/216431.pdf', 'source': {'id': 'https://openalex.org/S4306401067', 'display_name': 'Radboud Repository (Radboud University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I145872427', 'host_organization_name': 'Radboud University Nijmegen', 'host_organization_lineage': ['https://openalex.org/I145872427'], 'host_organization_lineage_names': ['Radboud University Nijmegen'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7545166', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.270.37.21612', 'pdf_url': 'http://www.jbc.org/article/S0021925818902188/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 63, 'referenced_works': ['https://openalex.org/W1482720254', 'https://openalex.org/W1499636416', 'https://openalex.org/W1504989678', 'https://openalex.org/W1512678034', 'https://openalex.org/W1529646916', 'https://openalex.org/W1531518952', 'https://openalex.org/W1548505291', 'https://openalex.org/W1552764442', 'https://openalex.org/W1560567906', 'https://openalex.org/W1566066927', 'https://openalex.org/W1568633684', 'https://openalex.org/W1580675778', 'https://openalex.org/W1593696535', 'https://openalex.org/W1594207045', 'https://openalex.org/W1599110926', 'https://openalex.org/W1605153099', 'https://openalex.org/W1613698407', 'https://openalex.org/W1877478601', 'https://openalex.org/W1939326027', 'https://openalex.org/W1964265039', 'https://openalex.org/W1967629973', 'https://openalex.org/W1972287742', 'https://openalex.org/W1974342547', 'https://openalex.org/W1975314092', 'https://openalex.org/W1975364338', 'https://openalex.org/W1986389803', 'https://openalex.org/W1990387345', 'https://openalex.org/W1999794993', 'https://openalex.org/W2003997440', 'https://openalex.org/W2004828817', 'https://openalex.org/W2008091979', 'https://openalex.org/W2012330153', 'https://openalex.org/W2013381560', 'https://openalex.org/W2020608323', 'https://openalex.org/W2022987420', 'https://openalex.org/W2025107609', 'https://openalex.org/W2029231027', 'https://openalex.org/W2036942644', 'https://openalex.org/W2037986253', 'https://openalex.org/W2047196924', 'https://openalex.org/W2059776541', 'https://openalex.org/W2060582555', 'https://openalex.org/W2060623940', 'https://openalex.org/W2065051915', 'https://openalex.org/W2081401313', 'https://openalex.org/W2081796018', 'https://openalex.org/W2089562291', 'https://openalex.org/W2105300288', 'https://openalex.org/W2106200811', 'https://openalex.org/W2111604219', 'https://openalex.org/W2115146277', 'https://openalex.org/W2126582015', 'https://openalex.org/W2130180403', 'https://openalex.org/W2133148589', 'https://openalex.org/W2140079145', 'https://openalex.org/W2140225796', 'https://openalex.org/W2142500412', 'https://openalex.org/W2143766900', 'https://openalex.org/W2146502475', 'https://openalex.org/W2158499405', 'https://openalex.org/W2161140556', 'https://openalex.org/W2170684533', 'https://openalex.org/W4256165053'], 'related_works': ['https://openalex.org/W2392388241', 'https://openalex.org/W2102514901', 'https://openalex.org/W2080351811', 'https://openalex.org/W2054037466', 'https://openalex.org/W2032180109', 'https://openalex.org/W2002445925', 'https://openalex.org/W1988655739', 'https://openalex.org/W1982694172', 'https://openalex.org/W1965866142', 'https://openalex.org/W1579343383'], 'abstract_inverted_index': {'We': [0, 205], 'investigated': [1, 206], 'the': [2, 5, 15, 55, 66, 80, 90, 102, 121, 131, 140, 151, 156, 172, 186, 199, 203, 207, 210, 220, 260, 271, 285, 295, 307, 326, 336, 345, 356, 361, 377, 391, 404, 408], 'influence': [3, 208], 'of': [4, 8, 94, 114, 123, 158, 161, 202, 209, 213, 299, 319, 328, 363, 366, 407], 'activation': [6, 200, 211, 405], 'state': [7, 201, 212, 406], 'integrin': [9, 214], 'α5β1': [10, 215], 'on': [11, 14, 198, 216, 219, 403], 'its': [12, 217], 'dependence': [13, 218], 'PHSRN': [16, 187, 221, 392], 'synergy': [17, 67, 188, 222, 272, 393], 'site': [18, 68, 189, 223, 273, 394], 'for': [19, 185, 190, 224, 390, 395], 'binding': [20, 58, 149, 225, 263, 354], 'to': [21, 34, 89, 101, 118, 130, 139, 150, 171, 193, 226, 239, 294, 306, 323, 335, 344, 355, 376, 398], 'RGD': [22, 194, 227, 399], 'in': [23, 72, 96, 155, 195, 228, 277, 301, 360, 400], 'fibronectin.': [24, 229], 'K562': [25, 77, 115, 148, 169, 230, 282, 320, 353, 374], 'and': [26, 32, 43, 61, 78, 116, 154, 166, 174, 231, 237, 248, 266, 283, 321, 359, 371, 379], 'MV3': [27, 97, 117, 128, 232, 302, 322, 333], 'cells': [28, 39, 233, 244], 'lacked': [29, 234], 'αvβ3': [30, 42, 95, 235, 247, 300], 'expression': [31, 236], 'adhered': [33, 40, 238, 245], 'fibronectin': [35, 47, 196, 240, 252, 401], 'through': [36, 41, 241, 246], 'α5β1.': [37, 44, 242, 249], 'Mel57': [38, 74, 243, 279], 'A': [45, 250], 'recombinant': [46, 251], 'polypeptide,': [48, 153, 253, 358], 'containing': [49, 254], 'five': [50, 255], 'type': [51, 256], 'III': [52, 257], 'repeats': [53, 258], 'from': [54, 259], 'central': [56, 261], 'cell': [57, 262], 'domain': [59, 264], '3Fn6-10,': [60, 265], 'a': [62, 159, 267, 364], 'mutated': [63, 81, 103, 132, 152, 173, 268, 286, 308, 337, 357, 378], 'polypeptide': [64, 82, 133, 176, 269, 287, 338, 381], 'lacking': [65, 270], 'were': [69, 274], 'equally': [70, 135, 178, 275, 340, 383], 'effective': [71, 276], 'promoting': [73, 278], 'adhesion.': [75, 280], 'For': [76, 281], 'MV3,': [79, 284], 'was': [83, 134, 177, 288, 339, 382], 'not': [84, 289], 'or': [85, 109, 125, 144, 290, 314, 330, 349], 'poorly': [86, 291], 'active': [87, 292], 'compared': [88, 293], 'control': [91, 141, 175, 296, 346, 380], 'polypeptide.': [92, 104, 142, 297, 309, 347], 'Expression': [93, 298], 'induced': [98, 111, 146, 303, 316, 351], 'strong': [99, 136, 304, 341], 'adhesion': [100, 113, 129, 138, 170, 192, 305, 318, 334, 343, 375, 397], 'TS2/16': [105, 124, 145, 310, 329, 350], 'stimulatory': [106, 311], 'β1-integrin': [107, 312], 'antibodies': [108, 313], 'Mn2+': [110, 143, 315, 348], 'α5β1-mediated': [112, 127, 168, 191, 317, 332, 373, 396], 'GRGDSP.': [119, 324], 'In': [120, 325], 'presence': [122, 157, 327, 362], 'Mn2+,': [126, 165, 331, 370], 'as': [137, 342], 'weak': [147, 352], 'combination': [160, 365], 'phorbol': [162, 367], '12-myristate': [163, 368], '13-acetate,': [164, 369], 'TS2/16,': [167, 372], 'strong.': [179, 384], 'Our': [180, 385], 'findings': [181, 386], 'demonstrate': [182, 387], 'that': [183, 388], 'requirement': [184, 389], 'depends': [197, 402], 'integrin.': [204, 409]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2012998128', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-14T03:55:24.499787', 'created_date': '2016-06-24'}