Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2012773090', 'doi': 'https://doi.org/10.1001/archneur.62.5.758', 'title': 'Predictors of Preclinical Alzheimer Disease and Dementia', 'display_name': 'Predictors of Preclinical Alzheimer Disease and Dementia', 'publication_year': 2005, 'publication_date': '2005-05-01', 'ids': {'openalex': 'https://openalex.org/W2012773090', 'doi': 'https://doi.org/10.1001/archneur.62.5.758', 'mag': '2012773090', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15883263'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/archneur.62.5.758', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210230857', 'display_name': 'Archives of Neurology', 'issn_l': '0003-9942', 'issn': ['0003-9942', '1538-3687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084326649', 'display_name': 'James E. Galvin', 'orcid': 'https://orcid.org/0000-0002-4561-0318'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James E. Galvin', 'raw_affiliation_strings': ["Department of Neurology, Alzheimer's Disease Research Center, School of Medicine, Washington University, St Louis, MO 63108, USA."], 'affiliations': [{'raw_affiliation_string': "Department of Neurology, Alzheimer's Disease Research Center, School of Medicine, Washington University, St Louis, MO 63108, USA.", 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071146971', 'display_name': 'Kimberly K. Powlishta', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kimberly K. Powlishta', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048202809', 'display_name': 'Kenneth L. Wilkins', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Kenneth Wilkins', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111553620', 'display_name': 'Daniel W. McKeel', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Daniel W. McKeel', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5114002779', 'display_name': 'Chengjie Xiong', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Chengjie Xiong', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111555817', 'display_name': 'Elizabeth Grant', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Elizabeth Grant', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016547093', 'display_name': 'Martha Storandt', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Martha Storandt', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063630764', 'display_name': 'John C. Morris', 'orcid': 'https://orcid.org/0000-0001-9820-5618'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'John C. Morris', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 8.706, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 194, 'citation_normalized_percentile': {'value': 0.938989, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '62', 'issue': '5', 'first_page': '758', 'last_page': '758'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10009', 'display_name': 'Dementia and Cognitive Impairment Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10009', 'display_name': 'Dementia and Cognitive Impairment Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10086', 'display_name': "Alzheimer's disease research and treatments", 'score': 0.9863, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/clinical-dementia-rating', 'display_name': 'Clinical Dementia Rating', 'score': 0.71061575}, {'id': 'https://openalex.org/keywords/cognitive-decline', 'display_name': 'Cognitive Decline', 'score': 0.5523935}, {'id': 'https://openalex.org/keywords/neuropathology', 'display_name': 'Neuropathology', 'score': 0.504449}], 'concepts': [{'id': 'https://openalex.org/C2779483572', 'wikidata': 'https://www.wikidata.org/wiki/Q83030', 'display_name': 'Dementia', 'level': 3, 'score': 0.95226604}, {'id': 'https://openalex.org/C2780906993', 'wikidata': 'https://www.wikidata.org/wiki/Q5133756', 'display_name': 'Clinical Dementia Rating', 'level': 4, 'score': 0.71061575}, {'id': 'https://openalex.org/C164953862', 'wikidata': 'https://www.wikidata.org/wiki/Q7256440', 'display_name': 'Psychomotor learning', 'level': 3, 'score': 0.58170646}, {'id': 'https://openalex.org/C2984863031', 'wikidata': 'https://www.wikidata.org/wiki/Q83030', 'display_name': 'Cognitive decline', 'level': 4, 'score': 0.5523935}, {'id': 'https://openalex.org/C169900460', 'wikidata': 'https://www.wikidata.org/wiki/Q2200417', 'display_name': 'Cognition', 'level': 2, 'score': 0.54172754}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.5202533}, {'id': 'https://openalex.org/C502032728', 'wikidata': 'https://www.wikidata.org/wiki/Q11081', 'display_name': "Alzheimer's disease", 'level': 3, 'score': 0.5121403}, {'id': 'https://openalex.org/C2780130745', 'wikidata': 'https://www.wikidata.org/wiki/Q1650750', 'display_name': 'Neuropathology', 'level': 3, 'score': 0.504449}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.48468497}, {'id': 'https://openalex.org/C2779504383', 'wikidata': 'https://www.wikidata.org/wiki/Q41482', 'display_name': 'Autopsy', 'level': 2, 'score': 0.46135828}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.449863}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.42101264}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.16323045}], 'mesh': [{'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D003704', 'descriptor_name': 'Dementia', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D008568', 'descriptor_name': 'Memory', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001057', 'descriptor_name': 'Apolipoproteins E', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001344', 'descriptor_name': 'Autopsy', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D001344', 'descriptor_name': 'Autopsy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003704', 'descriptor_name': 'Dementia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015577', 'descriptor_name': 'Geriatric Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008137', 'descriptor_name': 'Longitudinal Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008568', 'descriptor_name': 'Memory', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008609', 'descriptor_name': 'Mental Status Schedule', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009460', 'descriptor_name': 'Neurologic Examination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009483', 'descriptor_name': 'Neuropsychological Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011237', 'descriptor_name': 'Predictive Value of Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011594', 'descriptor_name': 'Psychometrics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011597', 'descriptor_name': 'Psychomotor Performance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018709', 'descriptor_name': 'Statistics, Nonparametric', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/archneur.62.5.758', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210230857', 'display_name': 'Archives of Neurology', 'issn_l': '0003-9942', 'issn': ['0003-9942', '1538-3687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15883263', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.65, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W1614256764', 'https://openalex.org/W1847168837', 'https://openalex.org/W1968832539', 'https://openalex.org/W1971744915', 'https://openalex.org/W1972340735', 'https://openalex.org/W1975505777', 'https://openalex.org/W1981802311', 'https://openalex.org/W1983611639', 'https://openalex.org/W1985621046', 'https://openalex.org/W1986852667', 'https://openalex.org/W1991952617', 'https://openalex.org/W1992974274', 'https://openalex.org/W2006933389', 'https://openalex.org/W2010846286', 'https://openalex.org/W2025290060', 'https://openalex.org/W2049155848', 'https://openalex.org/W2055101973', 'https://openalex.org/W2088584394', 'https://openalex.org/W2092129469', 'https://openalex.org/W2112150247', 'https://openalex.org/W2113708991', 'https://openalex.org/W2115077024', 'https://openalex.org/W2123056519', 'https://openalex.org/W2123535374', 'https://openalex.org/W2149614271', 'https://openalex.org/W2156220037', 'https://openalex.org/W2157299685', 'https://openalex.org/W2157359173', 'https://openalex.org/W2334899545', 'https://openalex.org/W2725718031'], 'related_works': ['https://openalex.org/W2991111086', 'https://openalex.org/W2925070304', 'https://openalex.org/W2750375652', 'https://openalex.org/W2465537596', 'https://openalex.org/W2409174684', 'https://openalex.org/W2292273527', 'https://openalex.org/W2122234393', 'https://openalex.org/W2045760871', 'https://openalex.org/W1978954528', 'https://openalex.org/W139999544'], 'abstract_inverted_index': {'To': [0], 'understand': [1], 'the': [2, 37, 215, 232], 'earliest': [3], 'signs': [4], 'of': [5, 39, 48, 62, 67, 87, 144, 160, 182, 210, 217, 231], 'cognitive': [6, 33, 83, 106, 164, 172, 206], 'decline': [7, 107, 116], 'caused': [8], 'by': [9, 177, 185], 'Alzheimer': [10], 'disease': [11], '(AD)': [12], 'and': [13, 32, 50, 64, 102, 169, 184], 'other': [14, 42], 'illnesses': [15], 'causing': [16], 'dementia,': [17], 'information': [18], 'is': [19], 'needed': [20], 'from': [21], 'well-characterized': [22], 'individuals': [23, 120, 145, 154, 191], 'without': [24, 155, 192, 220], 'dementia': [25, 80, 88, 111, 150, 156, 193, 203, 221], 'studied': [26], 'longitudinally': [27], 'until': [28], 'autopsy.To': [29], 'determine': [30], 'clinical': [31], 'features': [34], 'associated': [35], 'with': [36, 222], 'development': [38], 'AD': [40, 134, 138], 'or': [41], 'dementias': [43], 'in': [44, 92, 142], 'older': [45, 190, 218], 'adults.Longitudinal': [46], 'study': [47], 'memory': [49], "aging.Alzheimer's": [51], 'Disease': [52], 'Research': [53], 'Center,': [54], 'St': [55], 'Louis,': [56], 'Mo.Clinical': [57], 'Dementia': [58, 127, 179], 'Rating,': [59], 'its': [60], 'sum': [61, 181], 'boxes,': [63], 'neuropathologic': [65, 133], 'diagnosis': [66], 'dementia.Eighty': [68], 'control': [69], 'participants': [70], 'who': [71, 76, 121, 146, 194, 199], 'eventually': [72], 'came': [73], 'to': [74, 110], 'autopsy.Individuals': [75], 'did': [77, 147], 'not': [78, 148, 201], 'develop': [79, 195, 202], 'showed': [81, 157], 'stable': [82, 205], 'performance.': [84, 207], 'Entry': [85], 'predictors': [86], 'were': [89, 122], 'age,': [90, 166], 'deficits': [91], 'problem': [93], 'solving': [94], 'as': [95, 97, 174], 'well': [96], 'memory,': [98], 'slowed': [99, 186], 'psychomotor': [100, 187], 'performance,': [101, 188], 'depressive': [103, 167], 'features.': [104], 'Minimal': [105], 'occurred': [108], 'prior': [109], 'diagnosis,': [112], 'after': [113], 'which': [114, 225], 'sharp': [115], 'was': [117, 140], 'noted.': [118], 'Even': [119], 'minimally': [123], 'cognitively': [124], 'impaired': [125], '(Clinical': [126], 'Rating': [128, 180], '=': [129], '0.5)': [130], 'typically': [131], 'had': [132], 'at': [135, 151], 'autopsy.': [136], 'Histopathologic': [137], 'also': [139], 'present': [141], '34%': [143], 'have': [149, 204], 'death;': [152], 'these': [153], 'an': [158], 'absence': [159, 209], 'practice': [161, 211], 'effects': [162, 212], 'on': [163], 'testing.Increased': [165], 'features,': [168], 'even': [170], 'minimal': [171], 'impairment,': [173], 'determined': [175], 'clinically': [176], 'Clinical': [178], 'boxes': [183], 'identify': [189], 'dementia.': [196], 'Older': [197], 'adults': [198, 219], 'do': [200], 'The': [208], 'may': [213, 226], 'denote': [214], 'subset': [216], 'histopathologic': [223], 'AD,': [224], 'reflect': [227], 'a': [228], 'preclinical': [229], 'stage': [230], 'illness.': [233]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2012773090', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 20}, {'year': 2012, 'cited_by_count': 15}], 'updated_date': '2025-01-02T07:47:04.321528', 'created_date': '2016-06-24'}