Publication Information

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282, 313, 370, 522, 1359, 1465, 1640, 1786, 1805, 1904, 1947, 2141, 2170, 2190, 2225, 2239, 2274, 2397, 2400, 2546, 2562, 2607, 2662, 2757, 2784, 3641, 3662, 3711, 3746, 3788, 3931, 3965, 4057, 4141, 4199, 4250, 4375], 'myocytes': [18, 49, 106, 258, 283, 314, 371, 523, 1336, 1360, 1466, 1641, 1787, 1905, 1948, 2191, 2226, 2240, 2275, 2401, 2474, 2608, 2663, 2758, 2785, 2978, 3474, 3609, 3642, 3663, 3712, 3747, 3809, 3932, 3966, 4058, 4142, 4200, 4251, 4376, 4383], 'are': [19, 284, 1337, 3573, 4006, 4012, 4425], 'intrinsically': [20, 285], 'resistant': [21, 286], 'to': [22, 52, 156, 287, 317, 421, 1012, 1149, 1228, 1276, 1653, 1690, 1803, 1930, 2038, 2207, 2287, 2542, 2722, 2742, 2942, 2959, 3168, 3204, 3255, 3277, 3569, 3590, 3612, 3819, 3827, 4070, 4079, 4202, 4244, 4254, 4258, 4273, 4378, 4405], 'hypoxia-induced': [23, 288, 2136, 2164, 2228], 'apoptosis,': [24, 289], 'suggesting': [25, 290, 2651], 'protective': [27, 239, 292, 504, 4179, 4338], 'role': [28, 57, 293, 322, 729, 1772, 2104, 2148, 4261], 'energy-generating': [30, 295], 'substrates.': [31, 296], 'In': [32, 86, 297, 351, 2172], 'the': [33, 55, 80, 87, 154, 157, 162, 179, 194, 233, 238, 298, 320, 345, 352, 419, 422, 427, 444, 459, 498, 503, 599, 727, 735, 1076, 1083, 1088, 1105, 1168, 1173, 1229, 1241, 1290, 1297, 1455, 1469, 1479, 1543, 1634, 1659, 1671, 1694, 1698, 1770, 1797, 1849, 1855, 1901, 1931, 2033, 2039, 2046, 2103, 2114, 2121, 2125, 2146, 2173, 2193, 2202, 2208, 2385, 2394, 2538, 2581, 2695, 2716, 2720, 2743, 2783, 2830, 2853, 2872, 2904, 2948, 2960, 3121, 3126, 3156, 3195, 3245, 3278, 3282, 3288, 3355, 3360, 3434, 3517, 3555, 3576, 3615, 3648, 3686, 3726, 3773, 3784, 3812, 3841, 3856, 3936, 3976, 4040, 4043, 4061, 4091, 4095, 4103, 4106, 4119, 4130, 4140, 4208, 4216, 4225, 4248, 4260, 4267, 4274, 4308, 4330], 'present': [34, 299, 2126, 2174], 'report,': [35, 300], 'model': [37, 302], 'sustained': [39, 304], 'hypoxia': [40, 94, 223, 305, 359, 488, 791, 1474, 1654, 2179, 2610, 2640, 2693, 3613, 3771, 3842, 3853, 3973, 4080, 4203, 4255, 4296, 4406], 'primary': [42, 307, 1460, 2659], 'cultures': [43, 308, 1461, 2235, 2660], 'Percoll-enriched': [45, 310], 'neonatal': [46, 311, 1356, 1463, 2139, 2168, 2188, 2223, 2237, 3786], 'was': [50, 146, 315, 411, 1273, 2199, 2389, 2535, 2551, 2632, 2644, 2740, 2930, 3105, 3118, 3129, 3235, 3290, 3385, 3436, 3441, 3508, 3520, 3531, 3602, 3626, 3633, 3991, 4097, 4138, 4169, 4264, 4343], 'used': [51, 316, 2392, 2414], 'study': [53, 244, 318, 509, 2127, 2175], 'specifically': [54, 319, 2902, 3409], 'modulatory': [56, 321], 'extracellular': [59, 249, 324, 514], 'glucose': [60, 90, 325, 355, 1924, 1941, 2024, 2035, 2106, 2131, 2217, 3620, 3776, 3941, 3983, 4064, 4211, 4241, 4272, 4335, 4363, 4369, 4398], 'and': [61, 77, 82, 91, 97, 110, 128, 142, 159, 171, 185, 251, 262, 326, 342, 347, 356, 362, 375, 393, 407, 424, 436, 450, 516, 527, 545, 557, 561, 614, 622, 741, 987, 1009, 1116, 1166, 1234, 1287, 1303, 1357, 1364, 1678, 1703, 1708, 1824, 1854, 1866, 1883, 1913, 1926, 1943, 2020, 2041, 2108, 2133, 2160, 2219, 2308, 2319, 2364, 2391, 2404, 2469, 2587, 2602, 2609, 2636, 2703, 2711, 2734, 2810, 2849, 2881, 2897, 2912, 2984, 2986, 3096, 3125, 3163, 3211, 3247, 3308, 3318, 3341, 3370, 3443, 3477, 3516, 3525, 3535, 3628, 3728, 3798, 3803, 3821, 3825, 3847, 3872, 3942, 3984, 3997, 4003, 4072, 4076, 4229, 4283, 4300, 4402], 'other': [62, 92, 253, 327, 357, 518, 600, 1554], 'intermediary': [63, 328], 'substrates': [64, 329, 2231], 'energy': [66, 331, 1806, 1845, 2153], 'metabolism': [67, 332, 1807, 1850], '(pyruvate,': [68, 333], 'lactate,': [69, 219, 334, 484, 2161], 'propionate)': [70, 335], 'glycolytic': [74, 339], 'inhibitors': [75, 181, 340, 446, 1239, 1665, 1775, 4227], '(2-deoxyglucose': [76, 341], 'iodoacetate)': [78, 343], 'on': [79, 344, 1101, 1454, 2477, 2494, 2589, 3072, 3199, 3349, 3377, 3565, 3635], 'induction': [81, 346, 1456, 2029, 2115, 3780, 3960], 'maintenance': [83, 348, 553, 1932], 'apoptosis.': [85, 225, 264, 350, 490, 529, 1647, 2229, 2779, 3683, 3962, 4220], 'absence': [88, 353, 2194, 3651, 3774, 3939, 3980, 4209], 'substrates,': [93, 358], '(5%': [95, 360], 'CO2': [96, 361], '95%': [98, 363, 2709], 'N2)': [99, 364], 'caused': [100, 365, 1657, 3237], 'apoptosis': [101, 366, 603, 718, 732, 783, 1074, 1458, 1483, 1664, 2119, 2137, 2165, 2182, 2657, 2929, 3587, 3782, 3951, 4036, 4246, 4304], 'in': [102, 111, 193, 232, 367, 376, 458, 497, 564, 607, 734, 1075, 1092, 1099, 1120, 1295, 1354, 1361, 1365, 1459, 1542, 1639, 1666, 1776, 1954, 1957, 2026, 2113, 2120, 2124, 2162, 2186, 2192, 2210, 2294, 2321, 2406, 2594, 2623, 2658, 2699, 2754, 2760, 2788, 2804, 2815, 2818, 2828, 2834, 2838, 2847, 2870, 2876, 2922, 2936, 2973, 3021, 3103, 3120, 3139, 3143, 3313, 3479, 3538, 3614, 3647, 3762, 3772, 3779, 3783, 3811, 3840, 3855, 3888, 3935, 3975, 4060, 4102, 4118, 4207, 4247, 4252, 4266, 4374], '14%': [103, 368], 'at': [107, 115, 372, 380, 1163, 2291, 2384, 2481, 2499, 2528, 2746, 2822, 2863, 3089, 3109, 3132, 3223, 3263, 3364, 3428, 3510, 4276, 4333, 4346, 4360], '3': [108, 373, 2213, 2455, 3850, 3883, 3953], 'h': [109, 117, 374, 382, 1477, 2185, 2541, 2573, 2765, 3138, 3670, 3700, 3736, 3851, 3913, 4125, 4206, 4302, 4380], '22%': [112, 377], 'cells': [114, 379, 563, 1094, 1551, 1778, 2314, 2344, 2490, 2619, 2696, 2801, 2831, 2843, 2873, 2899, 2908, 2919, 2969, 3018, 3065, 3310, 3345, 3585, 3687, 3721, 3760, 3837, 3864, 3887, 3900, 3919, 3990, 4223, 4287], '6–8': [116, 381], 'hypoxia,': [119, 384, 1547, 1923, 3702, 3738, 3915], 'revealed': [121, 386, 3875], 'by': [122, 148, 176, 228, 387, 413, 441, 493, 537, 787, 1068, 1301, 1658, 1793, 2028, 2183, 2201, 2243, 2285, 2317, 2349, 2553, 3068, 3107, 3238, 3291, 3437, 3604, 3698, 3750, 3795, 3801, 3867, 3876, 3905, 3993, 4039, 4123, 4172, 4295, 4307, 4418], 'sarcolemmal': [123, 388], 'membrane': [124, 389, 541, 2732, 3868], 'blebbing,': [125, 390, 542, 3869], 'nuclear': [126, 391, 2913, 3799, 3873], 'fragmentation,': [127, 392, 548], 'chromatin': [129, 394, 543, 2910, 3727, 3870], 'condensation': [130, 395, 2911, 3724], '(Hoechst': [131, 396], 'staining),': [132, 397], 'terminal': [133, 398, 2425, 2949], 'deoxynucleotidyl': [134, 399, 2426, 2950], 'transferase-mediated': [135, 400, 2427, 2951], 'dUTP': [136, 401, 2428, 2952], 'nick': [137, 402, 2429, 2953], 'end': [138, 403, 2430, 2954], 'labeling': [139, 404, 2955], '(TUNEL)': [140, 405, 2956], 'staining,': [141, 406], 'DNA': [143, 172, 408, 437, 547, 2773, 2944, 3440, 3519, 3530, 3559, 3625, 3632, 3658, 3674, 3705, 4044, 4196, 4233, 4315], 'laddering.': [144, 409, 3571], 'This': [145, 243, 410, 508, 1539, 1896, 2197, 2631, 3116], 'accompanied': [147, 412, 2200, 4038], 'translocation': [149, 414, 2031, 2203], 'cytochrome': [151, 204, 416, 469, 1283, 2205, 3218, 3232, 3256], 'c': [152, 205, 417, 470, 2206, 3219, 3233], 'from': [153, 259, 418, 524, 1552, 1645, 1848, 1859, 1900, 1949, 2227, 2278, 2580, 3151, 4013, 4198], 'mitochondria': [155, 420, 3104], 'cytosol': [158, 423, 2209], 'cleavage': [160, 425, 4041, 4134, 4166, 4312, 4354, 4373, 4417], 'death': [163, 428, 535, 1090, 1123, 1174, 1299, 1353, 1695, 1701, 2939], 'substrate': [164, 429, 4050, 4263], 'poly(ADP-ribose)': [165, 169, 430, 434, 2433], 'polymerase.': [166, 431], 'Cleavage': [167, 432], 'polymerase': [170, 435], 'laddering': [173, 438, 2774, 3706, 4214, 4234, 4316], 'were': [174, 439, 1118, 2232, 2241, 2276, 2315, 2345, 2402, 2475, 2491, 2578, 2611, 2620, 2697, 2786, 2802, 2832, 2844, 2874, 2920, 2970, 2979, 2990, 3019, 3066, 3166, 3197, 3250, 3311, 3346, 3362, 3375, 3475, 3563, 3588, 3610, 3748, 3817, 3838, 3901, 3920, 3967, 4037, 4068, 4143, 4384, 4413], 'prevented': [175, 224, 440, 489, 2135, 3704, 4171, 4232, 4303, 4352], 'preincubation': [177, 442, 4285], 'with': [178, 443, 1282, 1343, 1682, 1693, 2451, 2557, 2597, 2634, 2852, 2886, 2981, 3078, 3213, 3252, 3523, 3527, 3533, 3682, 3688, 3754, 4114, 4145, 4176, 4182, 4224, 4355, 4386], 'caspase': [180, 198, 445, 463, 1305, 1310, 1683, 2212, 3695, 4053, 4153, 4161, 4174, 4226], 'benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl': [182, 447, 2436], 'ketone': [183, 187, 448, 452, 1864], '(zVAD-fmk)': [184, 449], 'benzyloxycarbonyl-Asp-Glu-Val-Asp-fluoromethyl': [186, 451, 2439], '(zDEVD-fmk),': [188, 453], 'indicating': [189, 454], 'activation': [190, 455], 'caspases': [192, 457, 1158, 1706], 'process.': [196, 461, 4269], 'The': [197, 207, 462, 472, 1064, 1268, 1822, 1881, 2312, 2343, 2382, 2399, 2489, 2618, 2842, 2965, 3064, 3149, 3344, 3505, 3529, 3580, 3640, 3719, 3930, 3986, 4184, 4238, 4422], 'inhibitor': [199, 464], 'zDEVD-fmk': [200, 465], 'also': [201, 466, 1004, 2044, 2144, 2492, 2971, 3713, 3777, 3902], 'partially': [202, 467], 'inhibited': [203, 468], 'translocation.': [206, 471], 'presence': [208, 234, 473, 499, 1635, 3616, 3649, 3813, 3937, 3977, 4062, 4217], 'little': [211, 476], '1': [213, 478, 2463, 2756, 3041, 3044, 3047, 3137, 3493, 3548, 3708, 3732], 'mm': [214, 479, 2456, 2534, 2725, 3030, 3033, 3036, 3039, 3042, 3045, 3329, 3486, 3489, 3544, 3549, 3619, 4282, 4351, 4362, 4397], 'glucose,': [215, 236, 250, 480, 501, 515, 2333], 'but': [216, 481], 'not': [217, 252, 482, 517, 1780, 2645, 2770, 3236, 3909, 4325], 'pyruvate,': [218, 483, 2159, 3943], 'propionate,': [221, 486], 'before': [222, 487], 'Inhibiting': [226, 491], 'glycolysis': [227, 247, 492, 512, 1927, 1944, 2109, 2134, 2220], '2-deoxyglucose': [229, 494], 'iodoacetate,': [231, 496], 'reversed': [237, 502], 'effect': [240, 505, 4180, 4191, 4358], 'glucose.': [242, 507, 2196], 'demonstrates': [245, 510], 'that': [246, 511, 730, 1111, 1293, 1840, 1903, 1940, 2105, 2178, 2652, 3231, 3408, 4132, 4240], 'metabolic': [254, 519], 'pathways,': [255, 520], 'protects': [256, 521], 'hypoxic': [260, 525, 1952, 3666, 4136], 'injury': [261, 526, 743, 1953], 'subsequent': [263, 528], 'Apoptosis,': [530], 'form': [532], 'characterized': [536], 'shrinkage,': [539], 'plasma': [540], 'condensation,': [544, 3871], 'genomic': [546, 3518], 'essential': [550], 'for': [551, 1471, 1478, 1916, 2561, 2639, 2763, 2812, 2860, 3074, 3113, 3136, 3217, 3351, 3367, 3383, 3513, 3594, 3621, 3668, 3832, 3844, 4051, 4081, 4204, 4291, 4399, 4407, 4415], 'development,': [552], 'tissue': [555, 1362, 2280], 'homeostasis,': [556], 'elimination': [558], 'harmful': [560], 'diseased': [562], 'metazoan': [565], 'organisms': [566], '(1Steller': [567], 'H.': [568, 749, 765, 795, 799, 1312, 1376, 1487, 1491, 1566, 1620, 2000, 3452], 'Science.': [569, 627, 1184, 1259], '1995;': [570, 628, 673, 878, 1388], '267:': [571, 629, 2265], '1445-1449Crossref': [572], 'PubMed': [573, 593, 631, 662, 676, 712, 776, 813, 835, 881, 910, 949, 982, 1059, 1136, 1188, 1223, 1252, 1263, 1330, 1446, 1505, 1534, 1590, 1608, 1628, 1741, 1764, 1974, 1990, 2014, 2065, 2093, 2270, 2379, 2522, 2687, 3012, 3189, 3399, 3468], 'Scopus': [574, 594, 632, 663, 677, 713, 777, 814, 836, 882, 950, 983, 1060, 1137, 1189, 1205, 1264, 1331, 1447, 1506, 1535, 1591, 1609, 1629, 1742, 1765, 1975, 1991, 2015, 2066, 2094, 2523, 2688, 3013, 3190, 3400, 3469], '(2419)': [575], 'Google': [576, 596, 634, 665, 679, 715, 762, 779, 816, 838, 853, 884, 911, 952, 985, 1031, 1062, 1139, 1191, 1207, 1224, 1253, 1266, 1333, 1391, 1416, 1449, 1508, 1537, 1593, 1611, 1631, 1744, 1767, 1977, 1993, 2017, 2068, 2096, 2271, 2380, 2525, 2690, 3015, 3192, 3402, 3471], 'Scholar,': [577, 635, 666, 680, 763, 885, 1192, 1208, 1254, 1392, 1417, 1509, 1594, 1612, 1745, 1978, 1994, 2069], '2Jacobson': [578], 'M.D.': [579, 2508, 3388], 'Weil': [580, 2509, 3389], 'M.': [581, 639, 688, 690, 702, 753, 793, 807, 1372, 1378, 1380, 1485, 1499, 1712, 1714, 1716, 1726, 2004, 2057, 2082, 2510, 2671, 3390], 'Raff': [582, 2511, 3391], 'M.C.': [583, 696, 2512, 3392], 'Cell.': [584, 941, 1129, 1321, 2085, 2513, 3003], '1997;': [585, 1028, 1185, 1215, 1322, 1531, 1738, 2087, 2514, 2679, 3004, 3186], '88:': [586, 1250, 2515], '347-354Abstract': [587, 2516], 'Full': [588, 590, 946, 1133, 1218, 1220, 1325, 1327, 1585, 1587, 2090, 2267, 2517, 2519, 2682, 2684, 3007, 3009, 3463, 3465], 'Text': [589, 591, 947, 1134, 1219, 1221, 1326, 1328, 1586, 1588, 2091, 2268, 2518, 2520, 2683, 2685, 3008, 3010, 3464, 3466], 'PDF': [592, 948, 1135, 1222, 1329, 1589, 2092, 2269, 2521, 2686, 3011, 3467], '(2383)': [595, 2524], 'Scholar).': [597, 716, 780, 1002, 1063, 1140, 1225, 1267, 1334, 1450, 1538, 1768, 1836, 1895, 2018, 2097, 2272, 2381, 2526, 2691, 3016, 3193, 3472], 'On': [598], 'hand,': [601], 'dysregulated': [602], 'has': [604, 722, 1779], 'been': [605, 1096, 1688, 1781], 'implicated': [606], 'many': [608, 788], 'human': [609, 3414], 'diseases': [610, 616], 'such': [611, 731, 1669], 'cancer': [613], 'neurodegenerative': [615], '(e.g.': [617], "Alzheimer's": [618], 'disease,': [619], 'AIDS': [620], 'encephalopathy,': [621], 'ischemic': [623, 742, 1950], 'stroke)': [624], '(3Thompson': [625], 'C.B.': [626, 3002, 3178], '1456-1462Crossref': [630], '(6159)': [633], '4Cheng': [636], 'Y.': [637, 649, 771, 1374, 1560, 1568, 1574, 1576, 1578], 'Deshmukh': [638], "D'Costa": [640], 'A.': [641, 647, 706, 887, 899, 903, 1318, 1760, 3185], 'Demaro': [642], 'J.A.': [643], 'Gidday': [644], 'J.M.': [645, 1256], 'Shah': [646], 'Sun': [648, 2077], 'Jacquin': [650], 'M.F.': [651], 'Johnson': [652], 'E.M.': [653], 'Holtzman': [654], 'D.M.': [655], 'J.': [656, 700, 757, 829, 843, 862, 875, 901, 904, 939, 976, 996, 1026, 1033, 1054, 1370, 1386, 1394, 1528, 1579, 1600, 1603, 1736, 2007, 2080, 2083, 2252, 2261, 2669, 2676, 3393, 3457], 'Clin.': [657, 830, 876, 905, 977, 997, 1529], 'Invest.': [658, 831, 849, 877, 906, 978, 998, 1412, 1530], '1998;': [659, 709, 773, 907, 943, 1202, 1260, 1443, 1582, 1605, 1625, 1761], '101:': [660, 908], '1992-1999Crossref': [661], '(474)': [664], '5Cotman': [667], 'C.W.': [668], 'Anderson': [669], 'A.J.': [670], 'Mol.': [671, 940, 2084], 'Neurobiol.': [672], '10:': [674], '19-45Crossref': [675], '(354)': [678], '6Roperch': [681], 'J.-P.': [682], 'Alvaro': [683], 'V.': [684, 967, 1722], 'Prieur': [685], 'S.': [686, 755, 797, 897, 1196, 1210, 1258, 1404, 1433, 1489, 1558, 1562, 1572, 1618, 1751, 1759, 1982, 1996, 2260, 3184], 'Tuynder': [687], 'Nemani': [689], 'Lethrosne': [691], 'F.': [692, 805, 1497], 'Piouffre': [693], 'L.': [694, 995, 1521, 2074, 2254], 'Gendron': [695], 'Israeli': [697], 'D.': [698, 965, 1732, 2370], 'Dausset': [699], 'Oren': [701], 'Amson': [703], 'R.': [704, 1037, 1596, 1616], 'Telerman': [705], 'Nat.': [707], 'Med.': [708, 1055], '4:': [710], '835-839Crossref': [711], '(155)': [714], 'Recently,': [717], 'heart': [720, 739, 1007, 1077, 1777], 'muscle': [721], 'elicited': [723], 'interest': [724], 'because': [725, 2647], 'potential': [728, 2147], 'plays': [733], 'development': [736], 'congestive': [738], 'failure': [740, 1008], '(7Sharov': [744], 'V.J.': [745], 'Sabbah': [746], 'H.N.': [747], 'Shimoyama': [748], 'Goussev': [750], 'A.V.': [751], 'Lesch': [752], 'Goldstein': [754], 'Am.': [756, 1025, 1385, 2008], 'Pathol.': [758, 1387], '1996;': [759, 850, 979, 999, 1056, 1249, 1413, 2376, 3396, 3460], '148:': [760], '141-149PubMed': [761], '8Yaoita': [764], 'Ogawa': [766], 'K.': [767, 769, 847, 895, 921, 1179, 1384, 1398, 1564, 1720, 1728, 2667, 3448, 3450], 'Maehara': [768], 'Maruyama': [770], 'Circulation.': [772, 2061], '97:': [774], '276-281Crossref': [775], '(564)': [778], 'Cardiac': [781, 1335, 2473, 2548, 2576, 2977, 3473, 3608, 3808], 'myocyte': [782, 2549], 'can': [784, 1945, 2655], 'be': [785, 1277, 1656], 'induced': [786, 2180], 'stimuli,': [789], 'including': [790, 1862], '(9Tanaka': [792, 1484], 'Ito': [794, 1383, 1486], 'Adachi': [796, 1488], 'Akimoto': [798, 1490], 'Nishikawa': [800, 1492], 'T.': [801, 803, 1382, 1493, 1495, 1747, 2256], 'Kasajima': [802, 1494], 'Marumo': [804, 1496], 'Hiroe': [806, 1498], 'Circ.': [808, 1441, 1500, 1969, 1985], 'Res.': [809, 1442, 1501, 1624, 1970, 1986], '1994;': [810, 832, 1130, 1502, 2062], '75:': [811, 1503], '426-433Crossref': [812, 1504], '(562)': [815, 1507], 'Scholar),': [817, 839, 854, 912, 953, 986, 1632], '(10Gottleib': [819], 'R.A.': [820, 824, 975], 'Burleson': [821], 'K.O.': [822], 'Kloner': [823], 'Babior': [825], 'B.M.': [826], 'Engler': [827], 'R.L.': [828], '94:': [833, 3187], '1621-1628Crossref': [834], '(1337)': [837], 'myocardial': [840, 1844, 1934], 'infarction': [841], '(11Kajstura': [842], 'Cheng': [844, 1395], 'W.': [845, 858, 1396], 'Reiss': [846, 894, 1397], 'Lab.': [848, 1411], '74:': [851, 1414], '86-107PubMed': [852, 1415], 'mechanical': [855], 'stretch': [856], '(12Cheng': [857], 'Li': [859, 863, 890], 'B.': [860, 932], 'Kajstura': [861, 900], 'P.': [864, 874, 923, 1410, 1718, 1980], 'Wolin': [865], 'M.S.': [866, 1194, 1517], 'Sonnenblick': [867, 1401], 'E.H.': [868, 1402], 'Hintze': [869], 'T.H.': [870], 'Olivetti': [871, 1407], 'G.': [872, 1368, 1408, 1435, 1753, 2002], 'Anversa': [873, 902, 1409], '96:': [879, 1000], '2247-2259Crossref': [880], '(577)': [883], '13Leri': [886], 'Claudio': [888], 'P.P.': [889], 'Q.': [891], 'Wang': [892, 896, 916, 935, 1319, 1422], 'X.': [893, 936, 1020, 1316, 1320, 1423, 1511], 'Malhotra': [898], '1326-1342Crossref': [909], 'staurosporine': [913], '(14Yue': [914], 'T.-L.': [915], 'C.': [917, 963, 1429, 1523, 1598, 1614, 1730], 'Romanic': [918, 1424], 'A.M.': [919, 1177, 1425, 1819, 1878, 3446], 'Kikly': [920], 'Keller': [922], 'DeWolf': [924], 'Jr.,': [925, 1437], 'W.E.': [926], 'Hart': [927], 'T.K.': [928], 'Thomas': [929], 'H.C.': [930], 'Storer': [931], 'Gu': [933, 1430], 'J.-L.': [934, 1724], 'Feuerstein': [937], 'G.Z.': [938, 1440], 'Cardiol.': [942, 2010, 2086], '30:': [944], '495-507Abstract': [945], '(151)': [951], 'tumor': [954], 'necrosis': [955], 'factor': [956], 'α': [957], '(15Krown': [958], 'K.N.': [959], 'Page': [960], 'M.T.': [961, 1527], 'Nguyen': [962, 2052, 2075], 'Zechner': [964], 'Gutierrez': [966], 'Comstock': [968], 'K.L.': [969], 'Glembotski': [970], 'C.C.': [971], 'Quintana': [972], 'P.J.E.': [973], 'Sabbadani': [974], '98:': [980], '2854-2865Crossref': [981], '(691)': [984], 'aortic': [988], 'constriction': [989], '(16Teiger': [990], 'E.': [991, 1245, 1815, 1874], 'Than': [992], 'V.D.': [993], 'Richard': [994], '2247-2259Google': [1001], 'Apoptosis': [1003], 'occurs': [1005], 'during': [1006, 1920, 2537], 'may': [1010, 1655, 2110], 'contribute': [1011], 'its': [1013, 1121, 4337], 'progression': [1014], '(17Li': [1015], 'Z.': [1016, 2368, 2665], 'Bing': [1017], 'O.H.L.': [1018], 'Long': [1019], 'Robinson': [1021], 'K.G.': [1022], 'Lakatta': [1023, 1524], 'E.G.': [1024, 1525], 'Physiol.': [1027], '272:': [1029, 2680], 'H2313-H2319PubMed': [1030], 'Scholar,18Narula': [1032], 'Haider': [1034], 'N.': [1035, 1052, 1570, 1749, 1998, 2006, 2053, 2076], 'Virmani': [1036], 'DiSalvo': [1038], 'T.G.': [1039], 'Kolodgie': [1040], 'F.D.': [1041], 'Haijjar': [1042], 'R.J.': [1043], 'Schmidt': [1044], 'U.': [1045, 1758, 3183], 'Semigran': [1046], 'M.J.': [1047], 'Dec': [1048], 'G.W.': [1049], 'Khaw': [1050], 'B.A.': [1051], 'Engl.': [1053], '335:': [1057], '1182-1189Crossref': [1058], '(1227)': [1061], 'underlying': [1065], 'molecular': [1066], 'mechanisms': [1067, 1638], 'which': [1069, 1109, 1236, 1548, 1642, 1686, 2627, 4334], 'these': [1070, 1550, 1667, 1774, 3751, 3836], 'diverse': [1071], 'stimuli': [1072], 'trigger': [1073], 'cells,': [1078, 1668], 'however,': [1079, 2642], 'remain': [1080, 1911], 'enigmatic.': [1081], 'Over': [1082], 'years': [1084], 'various': [1085, 2150], 'components': [1086], 'machinery': [1091], 'eukaryotic': [1093], 'have': [1095, 1144, 1467, 1687, 1938, 2101], 'identified,': [1097], 'based,': [1098], 'part,': [1100], 'genetic': [1102], 'analysis': [1103, 3171, 3301, 3591, 3598], 'nematode': [1106], 'Caenorhabditis': [1107], 'elegans,': [1108], 'showed': [1110, 3654, 3671, 3722, 3947, 4212], 'three': [1112, 1142, 4428], 'genes,': [1113], 'CED-3,': [1114], 'CED-4,': [1115], 'CED-9,': [1117], 'involved': [1119], 'cycle': [1124, 3092], '(19Hengartner': [1125], 'M.O.': [1126, 1200, 1513], 'Horvitz': [1127], 'H.R.': [1128], '76:': [1131], '665-676Abstract': [1132], '(1041)': [1138], 'All': [1141, 2604], 'genes': [1143, 1232], 'mammalian': [1145, 1153, 1230, 1269], 'homologs.': [1146], 'CED-3': [1147], 'corresponds': [1148, 1227], 'family': [1151], 'cysteine': [1154], 'proteases': [1155], 'known': [1156, 4049], '(a': [1159], 'total': [1160], '14,': [1162], 'last': [1164], 'count)': [1165], 'constitute': [1167], 'main': [1169], 'effector': [1170, 1309], 'arm': [1171], 'pathway': [1175], '(20Chinnaiyan': [1176], "O'Rourke": [1178, 3449], 'Lane': [1180], 'B.R.': [1181], 'Dixit': [1182, 3455], 'V.M.': [1183, 3456], '275:': [1186], '1122-1126Crossref': [1187], '(551)': [1190], '21Spector': [1193], 'Desnoyers': [1195], 'Hoeppner': [1197], 'D.J.': [1198], 'Hengartner': [1199], 'Nature.': [1201, 1737], '385:': [1203], '653-656Crossref': [1204], '(255)': [1206], '22Seshagiri': [1209], 'Miller': [1211], 'L.K.': [1212], 'Curr.': [1213], 'Biol.': [1214, 1580, 2262, 2677, 3395, 3458], '7:': [1216], '455-460Abstract': [1217], 'CED-9': [1226], 'anti-apoptotic': [1231], 'Bcl-2': [1233], 'BclXL,': [1235], 'serve': [1237], 'process': [1243, 1801, 2198], '(23Yang': [1244], 'Korsmeyer': [1246], 'S.J.': [1247], 'Blood.': [1248], '386-401Crossref': [1251], '24Adams': [1255], 'Corey': [1257], '281:': [1261], '1322-1326Crossref': [1262], '(4753)': [1265], 'homolog': [1270], 'CED-4': [1272], 'recently': [1274], 'discovered': [1275], 'Apaf-1': [1278], '(apoptosis-promoting': [1279], 'factor-1)': [1280], 'which,': [1281], 'c,': [1284], 'procaspase': [1285], '9,': [1286], 'dATP,': [1288], 'forms': [1289], 'so-called': [1291], 'apoptosome': [1292], 'participates': [1294], 'transmitting': [1296], 'final': [1298, 2530, 2748, 2868, 3153, 4278], 'signal': [1300, 3289, 3435], 'cleaving': [1302], 'activating': [1304], '3,': [1306, 3846, 4083, 4299, 4389], '(25Zou': [1311], 'Henzel': [1313], 'W.J.': [1314], 'Liu': [1315, 1426], 'Lutschg': [1317], '90:': [1323], '405-413Abstract': [1324], '(2715)': [1332], 'postmitotic,': [1338], 'terminally': [1339], 'differentiated': [1340], 'cells.': [1341], 'Hypoxia/ischemia,': [1342], 'without': [1345], 'reoxygenation,': [1346], 'potent': [1349], 'stimulator': [1350], 'both': [1355, 2895, 3244, 3306], 'adult': [1358], 'culture': [1363, 2497, 2744, 2793], 'vivo': [1366, 1955], '(26Itoh': [1367], 'Tamura': [1369], 'Suzuki': [1371, 1373], 'Ikeda': [1375], 'Koike': [1377], 'Nomura': [1379], 'Jie': [1381], '146:': [1389], '1325-1331PubMed': [1390], '27Kajstura': [1393], 'Clark': [1399], 'W.A.': [1400], 'Krajewski': [1403], 'Reed': [1405], 'J.C.': [1406], '28Yue': [1418], 'T.L.': [1419], 'Ma': [1420], 'X.L.': [1421], 'G.L.': [1427, 1966], 'Louden': [1428], 'J.L.': [1431, 1602, 1622], 'Kumar': [1432], 'Poste': [1434], 'Ruffolo': [1436], 'R.R.': [1438], 'Fererstein': [1439], '82:': [1444], '166-174Crossref': [1445], '(229)': [1448], 'Most': [1451], 'previous': [1452], 'reports': [1453], 'documented': [1468, 2102], 'need': [1470], 'long': [1472], 'term': [1473, 3770], '24–72': [1476], 'appearance': [1480, 3857, 4104], 'significant': [1482, 4219, 4245], '29Long': [1510], 'Boluyt': [1512], 'Hipolito': [1514], 'M.L.': [1515], 'Lundberg': [1516], 'Zheng': [1518], 'J.S.': [1519], "O'Neill": [1520], 'Cirielli': [1522], 'Crow': [1526], '99:': [1532], '2635-2643Crossref': [1533], '(270)': [1536], 'prolonged': [1540, 2042], 'viability': [1541], 'face': [1544], 'severe': [1546], 'distinguishes': [1549], 'some': [1553], 'types': [1556], '(30Yoshimura': [1557], 'Banno': [1559], 'Nakashima': [1561], 'Takenaka': [1563], 'Sakai': [1565, 1569], 'Nishimura': [1567], 'Shimizu': [1571], 'Eguchi': [1573], 'Tsujimoto': [1575], 'Nozawa': [1577], 'Chem.': [1581, 2263, 2678, 3459], '273:': [1583], '6921-6927Abstract': [1584], '(204)': [1592], '31Chihab': [1595], 'Bossenmeyer': [1597], 'Oillet': [1599], 'Daval': [1601, 1621], 'Neurochem.': [1604], '71:': [1606], '1177-1186Crossref': [1607], '(33)': [1610], '32Bossenmeyer': [1613], 'Chihab': [1615], 'Muller': [1617], 'Schroeder': [1619], 'Brain': [1623], '787:': [1626], '107-116Crossref': [1627], '(71)': [1630], 'suggests': [1633], 'intrinsic': [1637], 'protect': [1643], 'them': [1644], 'hypoxia-related': [1646], 'Some': [1648], 'this': [1650, 1800, 2892, 3152, 4262], 'relative': [1651], 'resistance': [1652], 'high': [1660], 'levels': [1661, 3949], 'endogenous': [1663], 'cellular': [1672], 'FLIPS': [1673], '(cFLIP)': [1674], '(cellular': [1675], 'FLICE-inhibitory': [1676], 'proteins)': [1677], 'ARC': [1679], '(apoptosis': [1680], 'repressor': [1681], 'recruitment': [1684], 'domain),': [1685], 'reported': [1689, 2249], 'interact': [1691], 'selectively': [1692, 2347], 'domain': [1696], 'Fas': [1699], '(CD95/Apo-1)': [1700], 'receptor': [1702], 'upstream': [1704], 'initiator': [1705], '2': [1707, 3056, 3514], '8,': [1709, 3547], 'respectively': [1710], '(33Irmler': [1711], 'Thome': [1713], 'Hahne': [1715], 'Schneider': [1717], 'Hofmann': [1719], 'Steiner': [1721], 'Bodmer': [1723], 'Schroter': [1725], 'Burns': [1727], 'Mattmann': [1729], 'Rimoldi': [1731], 'French': [1733], 'L.E.': [1734], 'Tschopp': [1735], '388:': [1739], '190-195Crossref': [1740], '(2205)': [1743], '34Koseki': [1746], 'Inohara': [1748], 'Chen': [1750, 2668], 'Nunez': [1752], 'Proc.': [1754, 3179], 'Natl.': [1755, 3180], 'Acad.': [1756, 3181], 'Sci.': [1757, 3182], '95:': [1762], '5156-5160Crossref': [1763], '(305)': [1766], 'However,': [1769, 1919, 2098, 3661], 'precise': [1771, 4331], 'documented.': [1782], 'Under': [1783, 4087], 'normoxic': [1784, 1909, 2767, 3645, 3764, 3830, 3890, 3945, 4088, 4289], 'conditions,': [1785, 3891, 3946], 'produce': [1788], 'most': [1789], 'their': [1791], 'ATP': [1792], 'oxidative': [1794], 'phosphorylation,': [1795], 'making': [1796], 'regulation': [1798], 'central': [1802], 'balancing': [1804], '(35Heineman': [1808], 'F.W.': [1809], 'Balaban': [1810], 'R.S.': [1811], 'Fozzard': [1812, 1871], 'H.A.': [1813, 1872], 'Haber': [1814, 1873], 'Jenings': [1816, 1875], 'R.B.': [1817, 1876], 'Katz': [1818, 1877], 'Morgan': [1820, 1879], 'H.E.': [1821, 1880], 'Heart': [1823, 1882], 'Cardiovascular': [1825, 1884], 'System:': [1826, 1885], 'Scientific': [1827, 1886], 'Foundations.': [1828, 1887], '2nd': [1829, 1888], 'Ed.': [1830, 1889], 'Raven': [1831, 1890], 'Press,': [1832, 1891], 'New': [1833, 1892], 'York1992:': [1834, 1893], '1641-1656Google': [1835], 'It': [1837], 'estimated': [1839], 'approximately': [1841, 3677, 4111], '60–70%': [1842], 'obtained': [1847, 2277], 'fatty': [1852, 2156], 'acids,': [1853], 'remaining': [1856], 'derived': [1858], 'non-lipid': [1860], 'sources': [1861], 'carbohydrates,': [1863], 'bodies,': [1865], 'amino': [1867], 'acids': [1868, 2157], '(36Tahiliani': [1869], 'A.G.': [1870], '1599-1620Google': [1894], 'fact': [1897, 4239], 'evident': [1899], 'observation': [1902], 'cultured': [1906, 2167, 2187, 2222, 2588, 2759, 3643, 3664, 3785, 3810, 3933, 3968, 4059, 4249], 'under': [1907, 2766, 2883, 3644, 3665, 3829, 3944, 3969, 4001, 4135, 4288], 'glucose-free': [1908], 'conditions': [1910, 2768, 3646, 3667, 3831, 4089, 4137, 4290], 'viable': [1912], 'beat': [1914], 'synchronously': [1915], 'several': [1917], 'days.': [1918], 'ischemia': [1921, 2021, 2043], 'uptake': [1925, 1942, 2025, 2107, 2132, 2218], 'become': [1928], 'critical': [1929], 'viability.': [1935], 'Multiple': [1936], 'studies': [1937, 2100, 2782], 'suggested': [1939], 'prevent': [1946, 2543], 'vitro': [1958], '(37Eberli': [1959], 'F.R.': [1960], 'Weinberg': [1961], 'E.O.': [1962], 'Grice': [1963], 'W.N.': [1964], 'Horowitz': [1965], 'Apstein': [1967], 'C.S.': [1968], '1991;': [1971], '68:': [1972], '466-481Crossref': [1973], '(203)': [1976], '38Owen': [1979], 'Dennis': [1981], 'Opie': [1983], 'L.H.': [1984, 3176], '1990;': [1987], '66:': [1988], '344-354Crossref': [1989], '(179)': [1992], '39Bekheit': [1995], 'Isber': [1997], 'Jani': [1999], 'Butrous': [2001], 'Boutjdir': [2003], 'El-Sherif': [2005], 'Coll.': [2009], '1993;': [2011], '22:': [2012], '1214-1222Crossref': [2013], '(8)': [2016], 'Hypoxia': [2019, 4099], 'induce': [2022, 2656], 'increased': [2023], 'part': [2027], 'transporter': [2036], 'GLUT-4': [2037], 'sarcolemma,': [2040], 'increases': [2045], 'expression': [2047], 'GLUT-1': [2049], '(40Sun': [2050], 'D.Q.': [2051, 2078], 'DeGrado': [2054], 'T.R.': [2055], 'Schwaiger': [2056, 2081], 'Brosius': [2058], 'III,': [2059, 2071], 'F.C.': [2060, 2072], '89:': [2063], '793-798Crossref': [2064], '(215)': [2067], '41Brosius': [2070], 'Yannan': [2073], 'Bartlett': [2079], '29:': [2088], '1675-1685Abstract': [2089], '(70)': [2095], 'no': [2099, 3655, 4190], 'play': [2111], 'either': [2112, 3934, 4146, 4173], 'prevention': [2117], 'heart.': [2122], 'Therefore,': [2123], 'we': [2128, 2176, 2900, 3790], 'investigated': [2129, 2145], 'whether': [2130, 4032], 'myocytes.': [2142, 2171, 2398], 'We': [2143, 4029], 'intermediaries': [2151], 'metabolism,': [2154], 'namely': [2155], '(propionate),': [2158], 'modulating': [2163], 'demonstrate': [2177], 'substantial': [2181, 3860], '3–8': [2184], 'activation-dependent': [2214], 'manner.': [2215], 'Only': [2216], 'protected': [2221], 'Other': [2230], 'ineffectual.': [2233], 'Primary': [2234], 'prepared': [2242, 2991, 3106], 'modification': [2245], 'protocol': [2248, 2962], 'previously': [2250, 3174], '(42Sadoshima': [2251], 'Jahn': [2253], 'Takahashi': [2255], 'Kulik': [2257], 'T.J.': [2258], 'Izumo': [2259], '1992;': [2264], '10551-10560Abstract': [2266], 'Briefly,': [2273, 3017, 3194], 'ventricular': [2279], '1-day-old': [2282], 'Wistar': [2283], 'rats': [2284], 'six': [2286], 'seven': [2288], '15-min': [2289], 'digestions': [2290], '37': [2292, 3511], '°C': [2293, 3366, 3512], 'HEPES-buffered': [2295], 'saline': [2296, 2806], 'solution': [2297], 'containing': [2298, 4065], '0.1%': [2299, 2302, 2835, 2839], 'collagenase': [2300], 'IV,': [2301], 'trypsin,': [2303], '15': [2304, 3368], 'μg/ml': [2305, 2464, 2471, 3050, 3054, 3057, 3060, 3502], 'DNase': [2306], 'I,': [2307], '1.0%': [2309], 'chicken': [2310], 'serum.': [2311], 'dissociated': [2313], 'collected': [2316, 2390, 2579, 3320], 'centrifugation': [2318, 2351, 3108], 'resuspended': [2320, 3020, 3119, 3478], 'ADS': [2322], 'buffer': [2323, 3027, 3123, 3327, 3359, 3484], '(in': [2324], 'g/liter:': [2325], '6.8': [2326], 'NaCl,': [2327, 3487], '4.76': [2328], 'HEPES,': [2329, 3034], '0.138': [2330], 'NaH2PO4,': [2331], '0.6': [2332], '0.4': [2334], 'KCl,': [2335, 3037], '0.205': [2336], 'MgSO4,': [2337], '0.002': [2338], 'phenol': [2339], 'red,': [2340], 'pH': [2341, 2808, 2820, 3062, 3316, 3331, 3491, 3546], '7.4).': [2342, 3063], 'then': [2346, 2850, 3319, 3347, 3536, 4077, 4284, 4403], 'enriched': [2348, 3102], 'differential': [2350], 'through': [2352], 'discontinuous': [2354], 'Percoll': [2355], '(Amersham': [2356, 3208, 3295], 'Pharmacia': [2357, 3209, 3296], 'Biotech)': [2358], 'gradient': [2359, 2584], 'densities': [2361], '1.050,': [2362], '1.062,': [2363], '1.082': [2365], 'g/ml': [2366], '(43Sheng': [2367], 'Pennica': [2369], 'Wood': [2371], 'W.I.': [2372], 'Chien': [2373, 2674], 'K.R.': [2374, 2675], 'Development.': [2375], '122:': [2377], '419-428Crossref': [2378], 'band': [2383], '1.062/1.082': [2386], 'density': [2387, 2483, 2501, 2583], 'interface': [2388], 'source': [2395], 'washed': [2403], 'suspended': [2405], "Dulbecco's": [2407, 2417], 'modified': [2408, 2418], "Eagle's": [2409, 2419], 'medium': [2410, 2444, 2625, 2745, 3824, 4067, 4075, 4275], '(DMEM)': [2411], '1The': [2412], 'abbreviations': [2413], 'are:': [2415], 'DMEM,': [2416], 'medium;': [2420], 'PBS,': [2421, 2819, 2829, 2871, 2983, 3315], 'phosphate-buffered': [2422, 2805], 'saline;': [2423], 'TUNEL,': [2424], 'labeling;': [2431], 'PARP,': [2432, 4047], 'polymerase;': [2434], 'Z-VAD-fmk,': [2435, 3691, 4149], 'ketone;': [2437, 2440], 'Z-DEVD-fmk,': [2438, 4158], 'Z-FA-fmk,': [2441], 'benzyloxycarbonyl-Phe-Ala-fluoromethyl': [2442], 'ketone/F-12': [2443], '(Life': [2445], 'Technologies,': [2446], 'Inc.)': [2447], '(1:1,': [2448], 'v/v)': [2449], 'supplemented': [2450, 2596], '5%': [2452, 2712], 'horse': [2453], 'serum,': [2454], 'pyruvic': [2457], 'acid,': [2458, 2462], '100': [2459, 2470, 2918, 3689, 4147, 4156], 'μm': [2460, 3690, 4148, 4157], 'ascorbic': [2461], 'transferrin,': [2465], '10': [2466, 2861, 3035, 3488, 3629], 'ng/ml': [2467], 'selenium,': [2468], 'ampicillin.': [2472], 'plated': [2476, 2493, 2622], 'gelatin-precoated': [2478], '60-mm': [2479], 'dishes': [2480], '2.5': [2485], '×': [2486, 2504, 3111, 3134], '106': [2487], 'cells/dish.': [2488], 'gelatin-coated': [2495, 2790], 'Falcon': [2496, 2791], 'slides': [2498, 2794], '1.5': [2503, 3038, 3224], '104': [2505], 'cells/cm': [2506], '(2Jacobson': [2507], 'Bromodeoxyuridine': [2527], 'concentration': [2531, 2749, 4279, 4332, 4348], '0.1': [2533, 3267], 'added': [2536, 2741], 'first': [2539, 3791], '36': [2540], 'proliferation': [2544], 'fibroblasts.': [2547], 'purity': [2550, 2567], 'monitored': [2552], 'immunofluorescence': [2554], 'after': [2555, 2574, 2613], 'staining': [2556, 3805, 3878, 3996], 'monoclonal': [2558, 3214, 3253, 3406], 'antibodies': [2559, 3215, 3254], 'specific': [2560, 3216], 'α-sarcomeric': [2563], 'actin': [2564], '(Sigma).': [2565], 'Myocyte': [2566], 'averaged': [2568], '96': [2569], '±': [2570, 3578, 3740, 3743, 3757, 3880, 3884, 3917, 3954, 4008], '3%': [2571, 3758, 3881], '48': [2572], 'plating.': [2575, 2617], 'fibroblasts': [2577], 'upper': [2582], '1.050/1.062': [2586], 'separate': [2590], 'untreated': [2591], '100-mm': [2592], 'plates': [2593], 'DMEM': [2595, 2638], '10%': [2598, 3337], 'fetal': [2599], 'calf': [2600], 'serum': [2601, 2643, 2653], 'antibiotics.': [2603], 'experiments': [2605], 'done': [2612], '4': [2614, 3756, 4193, 4236], 'days': [2615], 'initially': [2621], 'DMEM/F-12': [2624, 3823, 4066, 4074], '(1:1)': [2626], 'contained': [2628], '17.5': [2629, 3618, 3815, 4281, 4396], 'mmglucose.': [2630], 'replaced': [2633], 'glucose-': [2635, 3820, 4071], 'pyruvate-free': [2637, 3822, 4073], 'experiments;': [2641], 'removed': [2646], 'report': [2650], 'withdrawal': [2654, 4242], '(44Sheng': [2664], 'Knowlton': [2666], 'Hoshijima': [2670], 'Brown': [2672], 'J.H.': [2673], '5783-5791Abstract': [2681], '(346)': [2689], 'For': [2692, 2780, 2915, 3298], 'experiments,': [2694], 'placed': [2698, 3839], 'Plexiglas': [2701], 'chamber,': [2702], 'constant': [2705], 'stream': [2706], 'water-saturated': [2708], 'N2': [2710], 'CO2was': [2713], 'maintained': [2714], 'over': [2715], 'culture.': [2717], 'To': [2718, 3229, 3766, 4128, 4327], 'lower': [2719], 'Po2': [2721], '<': [2723, 3895, 3926, 4018, 4022], '5': [2724, 3059], 'Hg,': [2726], 'Oxyrase,': [2727], 'mixture': [2729], 'bacterial': [2731], 'monooxygenases': [2733], 'dioxygenases': [2735], '(Oxyrase': [2736], 'Inc.,': [2737, 3424], 'Ashland,': [2738], 'OH)': [2739], '2–6%.': [2751], 'As': [2752, 4164], 'shown': [2753, 4011, 4424], 'Fig.': [2755], '6%': [2761], 'Oxyrase': [2762, 3653], '24': [2764, 3622, 3669, 3699, 3735], 'do': [2769], 'show': [2771, 3714], 'any': [2772], 'morphologic': [2776, 4033], 'signs': [2777], 'morphological': [2781], 'grown': [2787], 'eight-well': [2789], 'glass': [2792], '(Becton': [2795], 'Dickinson': [2796], 'Labware,': [2797], 'Franklin': [2798], 'Lakes,': [2799], 'NJ).The': [2800], 'rinsed': [2803, 2845, 2980, 3312], '(PBS),': [2807], '7.4,': [2809, 2821, 3317], 'fixed': [2811], '30': [2813, 3114, 3833, 4292, 4400], 'min': [2814, 2862, 3083, 4293, 4401], '4%': [2816, 3741, 3918], 'paraformaldehyde': [2817], 'room': [2823, 2864], 'temperature.': [2824, 2865], 'After': [2825, 2866, 3354, 3551, 3734, 3911], 'rinse': [2827, 2869], 'permeabilized': [2833], 'Triton': [2836], 'X-100': [2837], 'sodium': [2840], 'citrate.': [2841], 'twice': [2846, 3522], 'PBS': [2848], 'stained': [2851], 'karyophilic': [2854], 'dye': [2855, 2893], 'Hoechst': [2856, 3802, 3877, 3994], '33258': [2857, 3995], '(5': [2858], 'μg/ml)': [2859], 'mounted': [2875], 'moiwol,': [2877], 'an': [2878, 3273], 'antifade': [2879], 'agent,': [2880], 'visualized': [2882], 'ultraviolet': [2884], 'light': [2885], 'Leitz': [2888], 'Orthoplan': [2889], 'microscope.': [2890], 'Because': [2891], 'stains': [2894], 'non-apoptotic': [2898], 'could': [2901], 'count': [2903], 'percentage': [2905, 3987], 'displaying': [2909], 'fragmentation.': [2914], 'statistical': [2916], 'analysis,': [2917], 'counted': [2921, 2972, 3998], 'five': [2923, 2974, 4014], 'different': [2924, 2975], 'fields.': [2925, 2976], 'Further': [2926], 'characterization': [2927], 'achieved': [2931, 4336], 'using': [2932, 2947, 3084, 3404], 'commercially': [2934], 'available': [2935], 'situ': [2937], 'detection': [2940], 'kit': [2941], 'find': [2943], 'strand': [2945], 'breaks': [2946], 'reagent': [2957], 'according': [2958], "manufacturer's": [2961], '(Boehringer': [2963], 'Mannheim).': [2964], 'number': [2966, 3861], 'TUNEL-positive': [2968, 3720], 'cold': [2982, 3314], 'mitochondrial,': [2985], 'cytosolic': [2987, 3157, 3164, 3248], '(S100)': [2988], 'fractions': [2989, 3165, 3249], '(45Vander': [2992], 'Heiden': [2993], 'M.G.': [2994], 'Chandel': [2995], 'N.S.': [2996], 'Williamson': [2997], 'E.K.': [2998], 'Schumacker': [2999], 'P.T.': [3000], 'Thompson': [3001, 3177], '91:': [3005], '627-637Abstract': [3006], '(1229)': [3014], '0.25': [3022], 'ml': [3023, 3481], 'ice-cold': [3025], 'isotonic': [3026], 'A': [3028, 3099], '(250': [3029], 'sucrose,': [3031], '20': [3032, 3075, 3352], 'MgCl2,': [3040], 'EDTA,': [3043], 'EGTA,': [3046], 'mmdithiothreitol,': [3048], '17': [3049], 'phenylmethylsulfonyl': [3051], 'fluoride,': [3052], '8': [3053, 3333, 3848, 3912, 4085, 4124, 4205, 4301, 4379, 4408], 'aprotonin,': [3055], 'leupeptin,': [3058], 'pepstatin,': [3061], 'disrupted': [3067], 'two': [3069, 3600], 'successive': [3070], 'sonications': [3071], 'ice': [3073, 3350], 's': [3076], 'each': [3077], 'pause': [3080], '1–2': [3082], 'microtip': [3086], 'generator': [3087], 'set': [3088], '40%': [3090], 'duty': [3091], '(Sonicator': [3093], 'Vibracell,': [3094], 'Sonics': [3095], 'Materials,': [3097], 'CT).': [3098], 'pellet': [3100, 3117], 'highly': [3101], '10,000': [3110], 'g': [3112, 3135], 'min.': [3115, 3834], 'same': [3122], 'A,': [3124], 'resulting': [3127], 'supernatant': [3128, 3150], 'further': [3130, 4329], 'spun': [3131], '160,000': [3133], 'TLA-100': [3141], 'rotor': [3142], 'Beckman': [3145], 'table': [3146], 'top': [3147], 'ultracentrifuge.': [3148], 'ultracentrifugation': [3154], 'represented': [3155], 'fraction.': [3158], 'Equivalent': [3159], 'amounts': [3160, 3372], 'mitochondrial': [3162, 3246, 3284], 'subjected': [3167, 3589, 3611, 4078, 4201, 4404], 'Western': [3169, 3299, 4419], 'blot': [3170, 3300, 4420], 'described': [3173, 4000], '(46Boise': [3175], '3759-3764Crossref': [3188], '(207)': [3191], 'proteins': [3196], 'electrophoresed': [3198, 3564], '15%': [3200], 'SDS-polyacrylamide': [3201, 3380], 'gels,': [3202], 'transferred': [3203], 'Hybond': [3205], 'nylon': [3206], 'membranes': [3207], 'Biotech),': [3210], 'immunoblotted': [3212], '(monoclonal': [3220, 3260, 3416], 'antibody': [3221, 3261, 3407, 3417], '7H8.2C12': [3222], 'μg/ml;': [3225, 3268], 'Pharmingen,': [3226], 'San': [3227], 'Diego).': [3228], 'ensure': [3230], 'release': [3234], 'physical': [3240], 'disruption': [3241], 'mitochondria,': [3243], 'probed': [3251], 'oxidase': [3257], '(subunit': [3258], 'IV)': [3259], '20E8-C12': [3262], 'dilution': [3265], 'Molecular': [3269], 'Probes,': [3270], 'Eugene,': [3271], 'OR),': [3272], 'enzyme': [3274, 4096], 'complex': [3275], 'bound': [3276], 'outer': [3279], 'leaflet': [3280], 'inner': [3283], 'membrane.': [3285], 'Visualization': [3286, 3432], 'enhanced': [3292], 'chemiluminescence': [3293], '(ECL)': [3294], 'Biotech).': [3297], 'PARP': [3303, 3384, 3415, 4133, 4168, 4311, 4353, 4372, 4416], '(poly(ADP-ribose)': [3304], 'polymerase),': [3305], 'floating': [3307], 'attached': [3309], 'into': [3321, 3659], 'defined': [3323], 'volume': [3324], 'lysis': [3326, 3483], '(62.5': [3328], 'Tris,': [3330, 3490], '6.8,': [3332], 'm': [3334], 'deionized': [3335], 'urea,': [3336], 'glycerol,': [3338], '2%': [3339, 3885], 'SDS,': [3340, 3496], 'protease': [3342], 'inhibitors).': [3343], 'sonicated': [3348], 's.': [3353], 'addition': [3356], 'loading': [3358], 'samples': [3361, 3560], 'incubated': [3363, 3509], '65': [3365], 'min,': [3369], 'equal': [3371], 'protein': [3374], 'resolved': [3376], '7.5%': [3379], 'gel.': [3381, 3639], 'Immunoblotting': [3382], 'performed': [3386, 3603], '(47Jacobson': [3387], 'Cell': [3394], '133:': [3397], '1041-1051Crossref': [3398], '(365)': [3401], 'Scholar)': [3403], 'detects': [3410], 'rat,': [3411], 'mouse,': [3412], 'SA-250;': [3418], 'clone': [3419], 'C-2–10,': [3420], 'BIOMOL': [3421], 'Research': [3422], 'Labs,': [3423], 'Plymouth': [3425], 'Meeting,': [3426], 'PA)': [3427], '1:5,000': [3430], 'dilution.': [3431], 'ECL.': [3438], 'Genomic': [3439, 3624, 4195], 'isolated': [3442, 4197], 'detected': [3444], '(48Chinnaiyan': [3445], 'Orth': [3447], 'Duan': [3451], 'Poirier': [3453], 'G.G.': [3454], '271:': [3461], '4573-4576Abstract': [3462], '(597)': [3470], 'harvested': [3476], '0.5': [3480], '(100': [3485], '8.0,': [3492], 'mmEDTA,': [3494], '0.5%': [3495], '0.20': [3497], 'mg/ml': [3498], 'proteinase': [3499], 'K,': [3500], '200': [3501, 3678], 'RNase': [3503], 'A).': [3504, 3709, 4127, 4194], 'lysate': [3507], 'h,': [3515], 'extracted': [3521], 'phenol/chloroform': [3524], 'once': [3526], 'chloroform.': [3528], 'precipitated': [3532], 'ethanol': [3534], 'dissolved': [3537], '50': [3539], 'μl': [3540], 'TE': [3542], '(10': [3543, 3561], 'Tris-HCl,': [3545], 'EDTA).': [3550], 'spectrophotometric': [3552], 'determination': [3553], 'nucleic': [3556], 'acid': [3557], 'content,': [3558], 'μg)': [3562], '1%': [3566, 3637], 'agarose': [3567, 3638], 'gels': [3568], 'visualize': [3570], 'Data': [3572, 4010], 'presented': [3574], 'means': [3577, 3581], 'S.E.': [3579, 4009], 'numbers': [3583], 'undergoing': [3586], 'variance': [3593], 'multiple': [3595], 'comparisons.': [3596], 'Paired': [3597], 'between': [3599], 'groups': [3601], "Student's": [3605], 't': [3606], 'test.': [3607], 'h.': [3623, 3849, 4086, 4409], 'isolated,': [3627], 'μg': [3630], 'run': [3634], 'fragmentation': [3656, 3675, 3874], 'oligonucleosomes.': [3660], 'characteristic': [3672, 4107], 'internucleosomal': [3673], 'base': [3679], 'pairs': [3680], 'consistent': [3681], 'Preincubation': [3684, 4221], 'broad': [3693, 4151], 'spectrum': [3694, 4152], 'inhibitor,': [3696, 4154, 4175], 'followed': [3697, 4294], 'completely': [3703, 4231], '(Fig.': [3707, 3731, 3806, 3897, 3928, 4192, 4235, 4313, 4364], 'Cultured': [3710], 'strongly': [3715, 3903], 'positive': [3716, 3904], 'TUNEL': [3717, 3804, 3906], 'staining.': [3718], 'distinct': [3723, 4213], 'fragmented': [3729], 'nuclei': [3730], 'B).': [3733, 4237], '16': [3739], '(mean': [3742], 'S.E.)': [3744], 'criteria': [3752], 'compared': [3753], 'only': [3755, 4090], 'observed': [3761, 4181], 'control,': [3763, 3889], 'conditions.': [3765], 'determine': [3767], 'if': [3768], 'short': [3769], 'resulted': [3778, 3854, 4101], 'myocytes,': [3789], 'examined': [3792, 4031], 'morphology': [3794, 3800, 4323], 'phase-contrast': [3796], 'microscopy': [3797], '2).': [3807], 'mmglucose': [3816], 'switched': [3818, 4069], 'allowed': [3826], 'equilibrate': [3828], 'Subsequently,': [3835], 'chamber': [3843], '1,': [3845, 4082, 4298, 4388], 'determined': [3866, 3992], '(14': [3879], 'versus': [3882], 'n': [3892], '=': [3893, 3923], '5,p': [3894], '0.05)': [3896], '3).': [3898, 3929], 'These': [3899], '(quantitative': [3907], 'data': [3908, 4423], 'shown).': [3910, 4326], '22': [3916], '(n': [3922], '5,': [3924, 4390], 'p': [3925, 4021], '0.001)': [3927], 'basal': [3948], '2%.Figure': [3955], '3Quantitative': [3956], 'analyses': [3957], 'time-dependent': [3959], 'normoxia': [3970], '(N)': [3971], '(H)': [3974], '(G+P+)': [3978], '(G−P−)': [3981], 'pyruvate.': [3985], 'dead': [3989], '"Materials': [4002], 'Methods."': [4004], 'Values': [4005], 'mean': [4007], 'independent': [4015, 4429], 'experiments.': [4016], '*p': [4017], '0.05,': [4019], '**': [4020], '0.001.View': [4023], 'Large': [4024, 4431], 'Image': [4025, 4432], 'Figure': [4026, 4433], 'ViewerDownload': [4027], '(PPT)': [4028], 'next': [4030], 'features': [4034], 'repair': [4045], 'enzyme,': [4046], 'activated': [4052], '3.': [4054], 'uncleaved,': [4092], 'proform': [4093, 4122], 'detected.': [4098], 'gradually': [4100], 'cleaved': [4108], 'fragment': [4109], '85': [4112], 'kDa,': [4113], 'dramatic': [4116], 'reduction': [4117], 'amount': [4120], '(Fig.4': [4126, 4317], 'test': [4129], 'possibility': [4131], 'caspase-dependent,': [4139], 'preincubated': [4144, 4385], 'more': [4160], '3-specific': [4162], 'inhibitor.': [4163], 'expected,': [4165], 'significantly': [4170], 'greater': [4178], 'Z-DEVD-fmk.': [4183], 'nonspecific': [4185], 'control': [4186], 'peptide': [4187], 'Z-FA-fmk': [4188], 'had': [4189], 'confirming': [4215], 'Z-VAD-fmk': [4228], 'Z-DEVD-fmk': [4230], 'led': [4243], 'response': [4253, 4367], 'prompted': [4256], 'us': [4257], 'examine': [4259], 'playing': [4265], 'Readdition': [4270], 'demonstrated': [4306], 'lack': [4309], '5),': [4314], 'B),': [4318], '(data': [4324], 'elucidate': [4328], 'effect,': [4339], 'dose-response': [4341], 'experiment': [4342], 'performed.': [4344], 'Glucose': [4345], '∼1.0': [4350], 'maximal': [4357], 'reached': [4359], '7.5': [4361], '6).Figure': [4365], '6Dose': [4366], 'protection': [4370], 'exposed': [4377], 'hypoxia.Cardiac': [4382], '0,': [4387], '7.5,': [4391], '10,': [4392], '12.5,': [4393], '15,': [4394], 'Total': [4410], 'lysates': [4412], 'analyzed': [4414], 'analyses.': [4421], 'representative': [4426], 'experiments.View': [4430], 'ViewerDow': [4434]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2012561199', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 10}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-28T04:02:45.651958', 'created_date': '2016-06-24'}