StAR-related Lipid Transfer (START) Proteins: Mediators of Intracellular Lipid Metabolism

Name: Work Video:
Duration: 3 min 30 s
Raymond E. Soccio; Jan L. Breslow
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[104], 'is': [105, 814, 919, 1148, 1290, 1301, 1356, 1403, 1800, 1851, 2012, 2053, 2157, 2317, 2325, 2782, 2930, 3052, 3111, 3184, 3223, 3472, 3505, 3557, 3806, 3866, 3974, 4060, 4101, 4108, 4116, 4240, 4258, 4394, 4424], 'the': [106, 199, 336, 409, 431, 452, 533, 568, 593, 653, 786, 820, 830, 834, 987, 1134, 1140, 1145, 1155, 1165, 1181, 1208, 1285, 1288, 1296, 1326, 1333, 1399, 1404, 1532, 1770, 1847, 1887, 2062, 2073, 2077, 2167, 2215, 2274, 2288, 2460, 2536, 2618, 2783, 2848, 3038, 3147, 3190, 3226, 3364, 3385, 3389, 3395, 3435, 3463, 3591, 3743, 3965, 3975, 4014, 4067, 4097, 4105, 4120, 4126, 4167, 4263], 'protein': [110, 141, 382, 481, 501, 1416, 2221, 2532, 3149, 3373, 3625, 4065, 4170], '(StAR),': [111], 'which': [112, 827, 1799, 2772, 2887, 3151, 3696, 3973, 4185, 4303], 'transfers': [113, 1423, 1909], 'cholesterol': [114, 607, 729, 778, 818, 841, 1130, 1323, 1330, 1414, 1536, 1947, 2173, 2269, 2285, 2409, 2474, 2653, 2768, 2798, 2890, 2936, 3061, 3076, 3193, 3707], 'to': [115, 604, 819, 842, 1128, 1133, 1144, 1215, 1280, 1328, 1332, 1362, 1428, 1538, 1542, 1769, 1854, 2069, 2174, 2419, 2423, 2535, 2769, 2800, 3079, 3141, 3225, 3313, 3512, 3708, 3913, 4306], 'mitochondria': [116, 1376, 1430, 1539, 1591, 2175, 2801, 3513], 'steroid': [118], 'hormone-producing': [119], 'cells': [120, 1381, 2230, 2918, 2973, 3257, 3293, 3873], '(1Stocco': [121, 848], 'D.M.': [122, 849, 1016, 1076, 1231, 1609], 'Annu.': [123, 546, 850, 3169, 3493], 'Rev.': [124, 547, 851, 3170, 3494], 'Physiol.': [125, 852], '2001;': [126, 420, 519, 709, 745, 853, 2139, 2395, 2874, 4383], '63:': [127, 854], '193-213Crossref': [128, 855], 'PubMed': [129, 176, 231, 350, 374, 423, 494, 527, 552, 629, 684, 717, 753, 804, 856, 874, 912, 944, 963, 1027, 1086, 1115, 1193, 1247, 1270, 1313, 1348, 1390, 1455, 1502, 1526, 1558, 1580, 1617, 1656, 1721, 1755, 1794, 1832, 1880, 1903, 1942, 1986, 2005, 2046, 2111, 2147, 2205, 2260, 2311, 2367, 2403, 2443, 2511, 2564, 2612, 2680, 2695, 2721, 2757, 2833, 2882, 2904, 2960, 2996, 3024, 3105, 3177, 3205, 3250, 3308, 3325, 3360, 3499, 3551, 3579, 3675, 3723, 3775, 3850, 3907, 3953, 4001, 4046, 4089, 4159, 4234, 4339, 4386, 4416], 'Scopus': [130, 177, 232, 351, 375, 424, 495, 528, 553, 630, 685, 718, 754, 805, 857, 875, 913, 945, 964, 1028, 1116, 1194, 1248, 1271, 1314, 1349, 1391, 1456, 1503, 1527, 1559, 1581, 1618, 1657, 1722, 1756, 1795, 1833, 1881, 1904, 1943, 1987, 2006, 2047, 2112, 2148, 2206, 2261, 2312, 2368, 2404, 2444, 2512, 2565, 2613, 2681, 2696, 2722, 2758, 2834, 2883, 2905, 2961, 2997, 3025, 3106, 3178, 3206, 3251, 3309, 3326, 3500, 3552, 3580, 3676, 3724, 3776, 3851, 3908, 3954, 4002, 4047, 4090, 4160, 4235, 4340, 4387, 4417], '(700)': [131, 858], 'Google': [132, 179, 234, 353, 377, 404, 426, 497, 530, 555, 590, 632, 687, 720, 756, 807, 859, 877, 915, 947, 966, 1030, 1087, 1118, 1196, 1250, 1273, 1316, 1351, 1393, 1458, 1505, 1529, 1561, 1583, 1620, 1659, 1686, 1724, 1758, 1797, 1835, 1883, 1906, 1945, 1989, 2008, 2049, 2114, 2150, 2208, 2263, 2314, 2370, 2406, 2446, 2514, 2567, 2615, 2683, 2698, 2724, 2760, 2836, 2885, 2907, 2963, 2999, 3027, 3108, 3180, 3208, 3253, 3311, 3328, 3361, 3420, 3502, 3554, 3582, 3678, 3726, 3778, 3853, 3910, 3956, 4004, 4049, 4092, 4162, 4237, 4342, 4389, 4419], 'Scholar).': [133, 180, 405, 556, 633, 688, 757, 808, 878, 916, 1088, 1197, 1274, 1317, 1352, 1394, 1459, 1530, 1562, 1621, 1687, 1836, 1884, 2009, 2151, 2209, 2264, 2315, 2407, 2447, 2515, 2568, 2616, 2699, 2837, 2964, 3028, 3109, 3181, 3362, 3503, 3555, 3679, 3727, 3779, 3957, 4005, 4050, 4093, 4163, 4238, 4343, 4390], 'found': [137], 'an': [139, 461, 767, 1367, 2326, 2470, 2529, 2845, 3473, 3920], 'extensive': [140], 'family,': [142], 'including': [143, 3432], 'only': [146, 154, 4396], 'multidomain': [148], 'proteins,': [149, 476, 1282], 'but': [150, 1032, 1154, 2163, 2457, 2540, 3116, 3262, 3485, 3509, 3613, 3786, 3870, 4058, 4104, 4171, 4251, 4359], 'ligands': [152], 'have': [153, 187, 332, 2296, 2450, 2655, 3032, 3749, 4285], 'been': [155, 333, 664, 2297, 2452, 2656, 3588, 3750], 'identified': [156, 2298, 2923, 3033], 'a': [158, 326, 448, 457, 563, 606, 643, 728, 1151, 1168, 1413, 1627, 1692, 2054, 2318, 2424, 2542, 2791, 2911, 2934, 3034, 3075, 3185, 3378, 3506, 3525, 3585, 3684, 3733, 3930, 4053, 4063, 4293, 4434], 'few': [159], 'cases': [160], '(2Ponting': [161], 'C.P.': [162, 2868], 'Aravind': [163, 417], 'L.': [164, 418, 673, 793], 'Trends': [165], 'Biochem.': [166, 868, 906, 1342, 1552, 3495, 4382, 4412], 'Sci.': [167, 224, 367, 622, 1020, 1240, 1748, 1825, 1979, 2039, 2198, 2253, 2605, 2673, 2953, 2989, 3098, 3243, 3668], '1999;': [168, 871, 909, 1345, 1555, 3576, 3672, 3945, 3993, 4038, 4081], '24:': [169, 961, 1268], '130-132Abstract': [170], 'Full': [171, 173, 522, 524, 712, 714, 748, 750, 1450, 1452, 1497, 1499, 1521, 1523, 1937, 1939, 2106, 2108, 2142, 2144, 2362, 2364, 2398, 2400, 2506, 2508, 2559, 2561, 2752, 2754, 2828, 2830, 2877, 2879, 3355, 3357, 3770, 3772, 3948, 3950, 3996, 3998, 4041, 4043, 4084, 4086, 4154, 4156, 4229, 4231], 'Text': [172, 174, 523, 525, 713, 715, 749, 751, 1451, 1453, 1498, 1500, 1522, 1524, 1938, 1940, 2107, 2109, 2143, 2145, 2363, 2365, 2399, 2401, 2507, 2509, 2560, 2562, 2753, 2755, 2829, 2831, 2878, 2880, 3356, 3358, 3771, 3773, 3949, 3951, 3997, 3999, 4042, 4044, 4085, 4087, 4155, 4157, 4230, 4232], 'PDF': [175, 526, 716, 752, 1454, 1501, 1525, 1941, 2110, 2146, 2366, 2402, 2510, 2563, 2756, 2832, 2881, 3359, 3774, 3952, 4000, 4045, 4088, 4158, 4233], '(344)': [178], 'human': [182, 3969, 4243], 'mouse': [184], 'genomes': [185], 'each': [186, 635, 4284], '15': [188, 241], 'genes': [189, 2295, 3058, 3158], 'encoding': [190], '(Table': [193], 'I),': [194], 'phylogenetic': [196], 'analysis': [197], 'divides': [198], 'family': [200], 'into': [201, 3596], 'six': [202], 'subfamilies': [203], '(Fig.': [204, 465, 844, 2427, 2775, 3598, 3754], '1,': [205], 'A': [206, 2516], 'B)': [208], '(3Soccio': [209, 2590, 2658, 2938, 2974, 3083, 3228], 'R.E.': [210, 359, 614, 2591, 2659, 2939, 2975, 3084, 3229], 'Adams': [211, 2592, 2660, 2940, 2976, 3085, 3230], 'R.M.': [212, 1994, 2593, 2661, 2941, 2977, 3086, 3231, 3568], 'Romanowski': [213, 2594, 2662, 2942, 2978, 3087, 3232], 'M.J.': [214, 357, 612, 1510, 2595, 2663, 2943, 2979, 3088, 3233], 'Sehayek': [215, 2596, 2664, 2944, 2980, 3089, 3234], 'E.': [216, 1595, 2597, 2665, 2733, 2809, 2945, 2981, 3090, 3235, 4139, 4214], 'Burley': [217, 362, 617, 2598, 2666, 2946, 2982, 3091, 3236], 'S.K.': [218, 363, 618, 2599, 2667, 2947, 2983, 3092, 3237], 'Breslow': [219, 360, 615, 2600, 2668, 2948, 2984, 3093, 3238], 'J.L.': [220, 361, 616, 2601, 2669, 2949, 2985, 3015, 3094, 3239], 'Proc.': [221, 364, 619, 1017, 1237, 1745, 1822, 1976, 2036, 2195, 2250, 2602, 2670, 2950, 2986, 3095, 3240, 3665], 'Natl.': [222, 365, 620, 1018, 1238, 1746, 1823, 1977, 2037, 2196, 2251, 2603, 2671, 2951, 2987, 3096, 3241, 3666], 'Acad.': [223, 366, 621, 1019, 1239, 1747, 1824, 1978, 2038, 2197, 2252, 2604, 2672, 2952, 2988, 3097, 3242, 3667], 'U.': [225, 368, 623, 1021, 1241, 1749, 1826, 1980, 2040, 2199, 2254, 2606, 2674, 2954, 2990, 3099, 3244, 3669], 'S.': [226, 369, 624, 1022, 1242, 1601, 1750, 1827, 1981, 2041, 2200, 2255, 2607, 2675, 2729, 2805, 2955, 2991, 3100, 3245, 3670, 3939, 3987, 4032, 4075, 4137, 4212], 'A.': [227, 370, 625, 791, 1023, 1243, 1751, 1828, 1982, 2042, 2121, 2201, 2256, 2377, 2608, 2676, 2956, 2992, 3101, 3246, 3538, 3633, 3636, 3646, 3671, 3840, 3897, 3935, 3983, 4028, 4071, 4131, 4206], '2002;': [228, 371, 401, 587, 626, 801, 1055, 1083, 1190, 1310, 1387, 1518, 1577, 1614, 1934, 2103, 2308, 2359, 2440, 2503, 2556, 2609, 2677, 2692, 2749, 2825, 2901, 2957, 2993, 3021, 3102, 3174, 3202, 3247, 3322, 3417, 3548, 3720, 3767, 4336], '99:': [229, 372, 627, 2610, 2678, 2958, 2994, 3103, 3248], '6943-6948Crossref': [230, 2611, 2679, 2959, 2995, 3104, 3249], '(155)': [233, 2614, 2682, 2962, 2998, 3107, 3252], 'Scholar).Table': [235], 'INomenclature': [236], 'chromosomal': [238], 'locations': [239], 'of': [240, 652, 661, 760, 817, 833, 890, 896, 1096, 1370, 1379, 1406, 1840, 2065, 2172, 2459, 2523, 3154, 3192, 3333, 3424, 3434, 3462, 3483, 3594, 3704, 3729, 3736, 3968, 3977, 4096], 'mammalian': [242], 'genesStarD': [244], 'nameOther': [245], 'namesMouseHumanStarD1StAR8,': [246], '24.5': [247], 'Mb8,': [248, 305], '37.4': [249], 'MbStAR': [250], 'pseudogene13,': [251], '59.8': [252], 'MbStarD2PCTP11,': [253], '90.7': [254], 'Mb17,': [255, 261], '53.6': [256], 'MbStarD3MLN64,': [257], 'es64,': [258], 'CAB111,': [259], '99.1': [260], '37.3': [262], 'MbStarD4CRSP18,': [263], '33.4': [264], 'Mb5,': [265, 299, 314], '110.5': [266], 'MbStarD5None7,': [267], '73.3': [268], 'Mb15,': [269, 288], '77.6': [270], 'MbStarD6None18,': [271], '70.8': [272], 'Mb18,': [273], '52.0': [274], 'MbStarD6': [275], 'pseudogene10,': [276], '56.8': [277], 'MbStarD7GTT12,': [278], '128.3': [279], 'Mb2,': [280], '94.7': [281], 'MbStarD8KIAA0189-RhoGAPX,': [282], '81.9': [283], 'MbX,': [284], '64.1': [285], 'MbStarD9KIAA13002,': [286], '121.1': [287], '38.4': [289], 'MbStarD10PCTP-like,': [290], 'SDCCAG28,': [291], 'CGI-527,': [292], '91.1': [293], 'Mb11,': [294], '74.8': [295], 'MbStarD11GPBP,': [296], 'COL4A3BP13,': [297], '93.9': [298], '73.5': [300], 'MbStarD12DLC-1,': [301], 'Arhgap7,': [302], 'p122-RhoGAP8,': [303], '35.5': [304], '12.7': [306], 'MbStarD13GT650,': [307], '4902678-RhoGAP5,': [308], '150.3': [309], 'Mb13,': [310], '31.7': [311], 'Mb(StarD14)CACH13,': [312], '88.9': [313], '80.8': [315], 'Mb(StarD15)THEA,': [316], 'BFIT,': [317], 'KIAA07074,': [318], '104.5': [319], 'Mb1,': [320], '54.8': [321], 'Mb': [322], 'Open': [323], 'table': [324], 'new': [327, 897], 'tab': [328], 'X-ray': [329], 'crystal': [330], 'structures': [331, 597], 'solved': [334], 'for': [335, 1126, 2056, 2621, 2847, 3283, 4023, 4349, 4354, 4362, 4445], 'MLN64': [337, 594, 1622, 1689, 1841, 1889, 2010, 2066, 2156, 2216, 2265, 2334, 2420, 2448, 2461, 2537], '(4Tsujishita': [340, 1893], 'Y.': [341, 736, 1676, 1706, 1865, 1894, 2860, 3824, 3844, 3881, 3901, 4377, 4407, 4409, 4456, 4458], 'Hurley': [342, 1895], 'J.H.': [343, 1896, 3644], 'Nat.': [344, 398, 584, 1897, 3414], 'Struct.': [345, 399, 585, 1898, 3415], 'Biol.': [346, 400, 517, 586, 707, 743, 870, 908, 1344, 1445, 1492, 1516, 1554, 1899, 1932, 2101, 2137, 2357, 2393, 2501, 2554, 2747, 2823, 2872, 3173, 3416, 3765, 3845, 3902, 3943, 3991, 4036, 4079, 4149, 4224], '2000;': [347, 491, 681, 1900, 2002, 3847, 3904, 4151, 4226], '7:': [348, 1901], '408-414Crossref': [349, 1902], '(450)': [352, 1905], 'Scholar),': [354, 378, 427, 498, 531, 591, 967, 1031, 1119, 1584, 1759, 1798, 2050, 2761, 2886, 2908, 3000, 3209, 3254, 3329, 3421, 3583, 3854, 3911, 4420], 'StarD4': [355, 596, 2569, 2625, 2762, 2920, 2928, 2965, 3039, 3051], '(5Romanowski': [356, 611], 'Soccio': [358, 613], '6949-6954Crossref': [373, 628], '(142)': [376, 631], '(PCTP)': [383], '(6Roderick': [384, 570, 3400], 'S.L.': [385, 571, 677, 3401], 'Chan': [386, 572, 674, 3402], 'W.W.': [387, 573, 675, 3403], 'Agate': [388, 574, 3404], 'D.S.': [389, 575, 3344, 3405], 'Olsen': [390, 576, 3406], 'L.R.': [391, 512, 577, 3407], 'Vetting': [392, 578, 3408], 'M.W.': [393, 579, 3409], 'Rajashankar': [394, 580, 3410], 'K.R.': [395, 581, 3411], 'Cohen': [396, 582, 678, 3412, 3762], 'D.E.': [397, 583, 679, 3413, 3566, 3763], '9:': [402, 588, 3418], '507-511PubMed': [403, 589, 3419], 'All': [406], 'three': [407], 'share': [408, 2572, 3377], 'same': [410], 'helix-grip': [411], 'fold': [412], '(7Iyer': [413], 'L.M.': [414, 506], 'Koonin': [415], 'E.V.': [416], 'Proteins.': [419], '43:': [421], '134-144Crossref': [422], '(192)': [425], 'with': [428, 451, 562, 923, 1203, 1955, 2072, 2333, 2464, 2473, 2583, 3002, 3055, 3560, 3608, 3628, 3746, 4201, 4248], 'α-helices': [429], 'at': [430, 774, 1180, 1284, 1398, 3258, 3454, 3529], 'N': [432, 1838], 'C': [434, 2276, 3966, 4068], 'termini': [435], 'separated': [436], 'by': [437, 881, 974, 2631, 2797, 3005, 3114, 3119, 3146, 3213, 3702, 3752, 3808, 4313], 'nine': [438], 'β-strands': [439], 'two': [441, 2293, 3926, 4286], 'shorter': [442], 'α-helices.': [443], 'curved': [445], 'β-sheet': [446], 'forms': [447, 3697], 'deep': [449], 'pocket': [450], 'C-terminal': [453, 654, 1848, 3931, 4294], 'α-helix': [454, 655], 'acting': [455], 'as': [456, 478, 1150, 1412, 1419, 1466, 1585, 1626, 2844, 2910, 2926, 3286, 3478, 4256], 'lid,': [458], 'resulting': [459], 'internal': [462], 'hydrophobic': [463, 473, 3396], 'cavity': [464, 474, 569, 3397], '2).': [466], 'structure': [469, 559], 'differs': [470], 'from': [471, 888, 1425, 2271, 2414, 3294, 3795, 3860, 4199], 'other': [472, 988, 1467, 1543, 2648, 3365, 3487, 4252], 'lipid-binding': [475, 3476], 'such': [477], 'carrier': [480], '2': [482], '(SCP-2)': [483], '(8Choinowski': [484], 'T.': [485, 931, 995, 1064, 1102, 1221, 1666, 1668, 1678, 1919, 2088, 2344, 2488, 2703, 3650, 4403, 4452], 'Hauser': [486], 'H.': [487, 1184, 1223, 1257, 1304, 1571, 1664, 1670, 1674, 1727, 1804, 1958, 2018, 2177, 2232, 2306, 2438, 3822, 3826, 3834, 3879, 3883, 3891], 'Piontek': [488], 'K.': [489, 697, 1070, 2735, 2811, 3828, 3838, 3842, 3885, 3895, 3899, 4373, 4375], 'Biochemistry.': [490, 680, 2001, 2717], '39:': [492, 682, 2003, 3353], '1897-1902Crossref': [493], '(63)': [496], 'phosphatidylinositol': [499], '(PITP)': [502], '(9Yoder': [503], 'M.D.': [504], 'Thomas': [505], 'Tremblay': [507], 'J.M.': [508, 2123, 2379, 3759], 'Oliver': [509], 'R.L.': [510], 'Yarbrough': [511], 'Helmkamp': [513], 'Jr.,': [514], 'G.M.': [515], 'J.': [516, 706, 742, 798, 866, 904, 939, 1081, 1110, 1340, 1384, 1444, 1491, 1515, 1550, 1611, 1716, 1875, 1931, 2100, 2131, 2136, 2356, 2387, 2392, 2500, 2553, 2639, 2689, 2746, 2822, 2871, 2898, 3018, 3046, 3068, 3135, 3199, 3272, 3302, 3319, 3349, 3536, 3642, 3717, 3764, 3830, 3887, 3941, 3942, 3989, 3990, 4034, 4035, 4077, 4078, 4145, 4147, 4148, 4220, 4222, 4223, 4381, 4411], 'Chem.': [518, 708, 744, 1446, 1493, 1517, 1933, 2102, 2138, 2358, 2394, 2502, 2555, 2748, 2824, 2873, 3766, 3944, 3992, 4037, 4080, 4150, 4225], '276:': [520, 710, 746, 2140, 2396, 2875], '9246-9252Abstract': [521], '(111)': [529], 'fatty': [534, 4308, 4446], 'acid-binding': [535], 'proteins': [536, 3010], '(FABPs)': [537], '(10Bernlohr': [538], 'D.A.': [539], 'Simpson': [540], 'M.A.': [541, 1998, 3654], 'Hertzel': [542], 'A.V.': [543], 'Banaszak': [544], 'L.J.': [545], 'Nutr.': [548], '1997;': [549, 1683, 1718, 1752, 1829, 1877, 1983, 2043, 2202, 2257], '17:': [550], '277-303Crossref': [551], '(196)': [554], 'PCTP': [558, 662, 3390, 3504, 3556, 3603, 3624, 3680, 3730, 3741], 'was': [560, 1035, 1624, 2519, 2922], 'reported': [561, 2453, 3607], '(PC)': [565], 'molecule': [566], 'whereas': [592, 1293, 1846, 2323, 3446], 'contain': [598, 4300], 'cavities': [599], 'large': [600], 'enough': [601], '(∼850': [602], 'Å3)': [603, 610], 'accommodate': [605], 'ligand': [608], '(∼740': [609], 'In': [634, 657, 1124, 1198, 1275, 1563, 2279, 2617, 2779, 2838, 3388, 3863], 'structure,': [636, 3391], 'entry': [638], 'or': [639, 650, 949, 1299, 1324, 1377, 3382, 3428, 3489, 4010], 'egress': [640], 'would': [641, 783], 'require': [642], 'major': [644], 'conformational': [645, 770], 'change,': [646], 'most': [647, 1177, 2581, 4121], 'likely': [648, 1178, 1761, 4110, 4255], 'opening': [649], 'unfolding': [651], 'lid.': [656], 'fact,': [658], 'this': [659, 2153, 2211, 2781, 3081, 3522, 3618, 3737], 'helix': [660], 'has': [663, 1212, 3587, 3919, 4345], 'membrane': [667, 837, 1137, 2531, 3187, 3745], 'PC': [670, 3399, 3484, 3595, 3611], 'extraction': [671], '(11Feng': [672], 'Roderick': [676], '15399-15409Crossref': [683], '(46)': [686], 'Furthermore,': [689], 'StAR': [690, 761, 892, 898, 918, 984, 1033, 1090, 1147, 1176, 1206, 1217, 1278, 1283, 1294, 1318, 1358, 1396, 1409, 1421, 1462, 1569, 1586, 1855, 2701], 'can': [691, 772, 1410, 2628, 2916], 'form': [692, 4123], 'partially': [693], 'unfolded': [694, 3148], 'states': [695], '(12Christensen': [696], 'Bose': [698, 1511], 'H.S.': [699, 929, 1100, 1512, 1992], 'Harris': [700], 'F.M.': [701], 'Miller': [702, 935, 1005, 1106, 1187, 1232, 1307, 1513, 1574, 1999, 2712], 'W.L.': [703, 862, 900, 936, 1006, 1107, 1188, 1233, 1308, 1336, 1514, 1546, 1575, 2000, 2713], 'Bell': [704], 'J.D.': [705, 3013], '17044-17051Abstract': [711], '(59)': [719], 'Scholar)': [721, 948, 1907, 1946, 3312], 'loses': [723], 'helical': [724], 'content': [725], 'upon': [726, 2521, 3514], 'analogue': [730], '(13Petrescu': [731], 'A.D.': [732], 'Gallegos': [733], 'A.M.': [734], 'Okamura': [735], 'Strauss': [737, 863, 901, 932, 1000, 1103, 1234, 1262, 1337, 1441, 1488, 1547, 1742, 1819, 1928, 1973, 2033, 2097, 2192, 2247, 2353, 2497, 2714], 'III,': [738, 864, 902, 933, 1001, 1104, 1235, 1263, 1338, 1442, 1489, 1548, 1743, 1820, 1929, 1974, 2034, 2098, 2193, 2248, 2354, 2498, 2715], 'J.F.': [739, 865, 903, 934, 1002, 1105, 1236, 1264, 1339, 1443, 1490, 1549, 1744, 1821, 1930, 1975, 2035, 2099, 2194, 2249, 2300, 2355, 2432, 2499, 2716, 3640], 'Schroeder': [740], 'F.': [741, 1219, 1253, 1729, 1806, 1921, 1960, 2020, 2090, 2117, 2179, 2234, 2346, 2373, 2490, 2546, 3164, 3937, 3985, 4030, 4073, 4133, 4143, 4208, 4218, 4379, 4405, 4454], '36970-36982Abstract': [747], '(109)': [755], 'Recent': [758], 'modeling': [759], 'using': [762, 1277, 2924], 'structure-based': [763], 'thermodynamics': [764], 'showed': [765], 'that': [766, 777, 1357, 2331, 2793, 2915, 3440, 3740, 3748, 4165, 4440], 'open': [768], 'lid': [769, 781], 'state': [771], 'exist': [773], 'equilibrium': [775], 'closure': [782], 'significantly': [784], 'stabilize': [785], 'complex': [787], '(14Mathieu': [788], 'A.P.': [789, 3534], 'Fleury': [790], 'Ducharme': [792], 'Lavigne': [794], 'P.': [795, 1649, 1712, 1787, 1871, 1913, 2082, 2302, 2338, 2434, 2482, 2739, 2745, 2815, 2821, 2895, 3275, 3664, 3714, 4135, 4210], 'LeHoux': [796], 'J.G.': [797, 2858], 'Mol.': [799, 869, 907, 1053, 1343, 1553, 3303], 'Endocrinol.': [800], '29:': [802], '327-345Crossref': [803], '(70)': [806], 'StAR—The': [809], 'rate-limiting': [810], 'step': [811, 2785], 'steroidogenesis': [813, 886, 973, 1952, 2058, 2161, 2630], 'StAR-mediated': [815], 'delivery': [816, 2171, 2799], 'P450': [821], 'side': [822, 832], 'chain': [823, 4356, 4368], 'cleavage': [824], 'enzyme': [825], '(P450scc/Cyp11A1),': [826], 'resides': [828], 'on': [829, 1373, 2933, 3784, 4266], 'matrix': [831, 1174, 1300], '(IMM)': [838], 'converts': [840], 'pregnenolone': [843], '3,': [845, 2428, 2776, 3599, 3755], 'pathway': [846, 2429, 2777, 3600, 3756], '2)': [847], 'Scholar,': [860, 1058, 1251, 1506, 1660, 1725, 1990, 2115, 2371, 2684, 2725], '15Miller': [861], 'Steroid': [867, 905, 1341, 1551], '69:': [872, 910, 1346, 1556], '131-141Crossref': [873, 911, 1347, 1557], '(148)': [876, 914, 1350, 1560], 'After': [879], 'stimulation': [880], 'pituitary': [882], 'trophic': [883], 'hormones,': [884], 'results': [887, 2468, 3731], 'phosphorylation': [889, 3527], 'pre-existing': [891], 'rapid': [894], 'synthesis': [895, 3194, 4450], '(15Miller': [899, 1335, 1545], 'When': [917], 'mutated': [920], 'humans': [922], 'congenital': [924], 'lipoid': [925], 'adrenal': [926, 975], 'hyperplasia': [927], '(16Bose': [928, 1099], 'Sugawara': [930, 1101, 1220], 'N.': [937, 1108, 1599, 1662, 2897, 3716, 3832, 3889, 4371], 'Engl.': [938, 1109], 'Med.': [940, 1111, 3304], '1996;': [941, 1112, 1244], '335:': [942, 1113], '1870-1878Crossref': [943, 1114], '(534)': [946, 1117], 'knock-out': [950, 3604], 'mice': [951, 3605], '(17Caron': [952], 'K.M.': [953], 'Soo': [954], 'S.C.': [955], 'Parker': [956, 1073], 'K.L.': [957, 1074, 2864], 'Endocr.': [958, 1265, 1612], 'Res.': [959, 1266, 1613, 1682, 3351, 3547, 4335], '1998;': [960, 1267, 1447, 1494, 3305, 3352], '827-834Crossref': [962], '(18)': [965], 'there': [968, 3856], 'marked': [970], 'defects': [971], 'cortex': [976], 'gonads.': [978], 'Early': [979], 'studies': [980, 1202, 1276], 'did': [981], 'not': [982, 2451, 3112, 3263, 3376, 3486, 3871, 4102, 4172], 'detect': [983, 2219], 'mRNA': [985, 2929, 2966, 3805, 4115], 'organs,': [990], 'placenta': [991, 2227], 'brain': [993], '(18Sugawara': [994], 'Holt': [996, 1226, 2706], 'J.A.': [997, 1227, 1925, 2094, 2350, 2494, 2707], 'Driscoll': [998], 'D.': [999, 1004, 1008, 1229, 1708, 1867, 2688, 2705, 2731, 2737, 2741, 2807, 2813, 2817, 3168, 3198, 3656], 'Lin': [1003, 2704, 3343], 'Patterson': [1007], 'Clancy': [1009], 'K.P.': [1010], 'Hart': [1011], 'I.M.': [1012], 'Clark': [1013], 'B.J.': [1014], 'Stocco': [1015, 1075, 1230, 1608], '1995;': [1024, 1653, 1791, 2718], '92:': [1025], '4778-4782Crossref': [1026], '(349)': [1029], 'expression': [1034, 2011, 3124, 3222], 'recently': [1036], 'shown': [1037], 'both': [1039, 2624, 4431], 'tissues': [1040, 2016, 2582, 3797], '(19Koh': [1041], 'P.O.': [1042], 'Kim': [1043], 'Y.S.': [1044], 'Cheon': [1045], 'E.W.': [1046], 'Kang': [1047], 'S.S.': [1048], 'Cho': [1049], 'G.J.': [1050], 'Choi': [1051], 'W.S.': [1052], 'Cell.': [1054], '14:': [1056], '355-360Google': [1057], '20King': [1059], 'S.R.': [1060], 'Manna': [1061], 'P.R.': [1062], 'Ishii': [1063], 'Syapin': [1065], 'P.J.': [1066], 'Ginsberg': [1067], 'S.D.': [1068, 2866], 'Wilson': [1069], 'Walsh': [1071], 'L.P.': [1072], 'Smith': [1077], 'R.G.': [1078], 'Lamb': [1079], 'D.J.': [1080], 'Neurosci.': [1082], '22:': [1084], '10613-10620Crossref': [1085], 'However,': [1089, 1460, 2061, 3602], 'null': [1091], 'fetuses': [1092], 'produce': [1093], 'normal': [1094, 3609], 'levels': [1095, 2585, 2967, 3562, 3626, 4444], 'placental': [1097], 'progesterone': [1098], 'suggesting': [1120, 3468, 3739, 4439], 'alternate': [1121, 1354], 'mechanisms.': [1123], 'order': [1125], 'P450scc': [1127, 1956], 'act,': [1129, 1363], 'must': [1131, 1359], 'get': [1132], '(OMM),': [1138], 'across': [1139], 'intermembranous': [1141, 1297], 'space,': [1142], 'IMM.': [1146], 'synthesized': [1149], '37-kDa': [1152], 'protein,': [1153, 2322, 3477, 3508], 'N-terminal': [1156, 2526, 3921], 'presequence': [1157, 1209, 1533], 'directs': [1158], 'import': [1160, 1565], 'before': [1161], 'being': [1162, 3189], 'cleaved': [1163], 'matrix,': [1166], 'leaving': [1167], '30-kDa': [1169], 'protein.': [1170], 'Despite': [1171], 'its': [1172], 'final': [1173], 'localization,': [1175, 2154], 'acts': [1179, 1397], 'OMM': [1182, 1286, 1327, 1368], '(21Bose': [1183, 1303, 1570], 'Lingappa': [1185, 1305, 1572], 'V.R.': [1186, 1306, 1573], 'Nature.': [1189, 1309, 1576], '417:': [1191, 1311, 1578], '87-91Crossref': [1192, 1312, 1579], '(294)': [1195, 1315, 1582], 'transfection': [1199, 1378, 3030], 'assays': [1200, 3031], 'isolated': [1204, 1375, 1888], 'mitochondria,': [1205, 1471], 'lacking': [1207], '(N-62': [1210], 'StAR)': [1211], 'equivalent': [1213], 'activity': [1214, 4059, 4348, 4353, 4361, 4393, 4423], 'full-length': [1216, 2155, 2220, 4169], '(22Arakane': [1218], 'Nishino': [1222], 'Liu': [1224, 1912, 2081, 2301, 2337, 2433, 2481], 'Z.': [1225, 1593], 'Pain': [1228], '93:': [1245], '13731-13736Crossref': [1246], '(254)': [1249], '23Arakane': [1252], 'Kallen': [1254, 1732, 1809, 1963, 2023, 2182, 2237], 'C.B.': [1255, 1432, 1479, 1733, 1810, 1964, 2024, 2183, 2238], 'Watari': [1256, 2305, 2437], 'Stayrook': [1258, 1437, 1484], 'S.E.': [1259, 1438, 1485, 3761, 4332], 'Lewis': [1260, 1439, 1486], 'M.': [1261, 1440, 1487, 1672, 1680, 1911, 1923, 2080, 2092, 2336, 2348, 2480, 2492, 3162, 3299, 3348, 3818, 3820, 3836, 3875, 3877, 3893], '463-468Crossref': [1269], '(32)': [1272], 'fusions': [1279], 'facing': [1287, 2076], 'cytosol': [1289, 2078, 4401], 'fully': [1291], 'active,': [1292], 'space': [1298], 'inactive': [1302, 2159], 'could': [1319, 1690, 2165, 2410, 3280], 'simply': [1320], 'drop': [1321], 'off': [1322], 'alter': [1325], 'facilitate': [1329, 3080, 3339], 'desorption': [1331], 'IMM': [1334], 'An': [1353], 'view': [1355], 'be': [1360, 2795, 3281], 'imported': [1361], 'because': [1364], 'data': [1365], 'supporting': [1366], 'site': [1369, 3191, 3528, 4100], 'action': [1371], 'rely': [1372], 'non-physiological': [1374], 'non-steroidogenic': [1380], '(24Jefcoate': [1382], 'C.': [1383, 1637, 1639, 1641, 1698, 1700, 1704, 1731, 1735, 1775, 1777, 1779, 1808, 1812, 1857, 1859, 1863, 1962, 1966, 2022, 2026, 2125, 2133, 2181, 2185, 2236, 2240, 2381, 2389, 2548, 2552], 'Clin.': [1385, 2690, 2899, 3019, 3200, 3320, 3718], 'Invest.': [1386, 2691, 2900, 3020, 3201, 3321, 3719], '110:': [1388, 2693, 2902, 3203, 3323, 3721], '881-890Crossref': [1389], '(141)': [1392], 'If': [1395], 'then': [1401], 'what': [1402], 'purpose': [1405], 'import?': [1408], 'act': [1411], 'vitro,': [1418], 'N-62': [1420, 1461], 'selectively': [1422], 'sterols': [1424, 3287, 3490], 'donor': [1426], 'liposomes': [1427], 'acceptor': [1429, 2426], '(25Kallen': [1431, 1478], 'Billheimer': [1433, 1480], 'J.T.': [1434, 1481], 'Summers': [1435, 1482], 'S.A.': [1436, 1483], '273:': [1448, 1495], '26285-26288Abstract': [1449, 1496], '(177)': [1457, 1504], 'lacks': [1463, 4052, 4125], 'target': [1464, 3057, 3976], 'specificity,': [1465], 'acceptors': [1468], 'include': [1469], 'trypsin-treated': [1470], 'reticulum': [1473], '(ER),': [1474], 'phospholipid': [1476], 'vesicles': [1477], '26Tuckey': [1507], 'R.C.': [1508], 'Headlam': [1509], '277:': [1519, 1935, 2104, 2360, 2504, 2557, 2750, 2826, 3768], '47123-47128Abstract': [1520], '(53)': [1528], 'Therefore,': [1531], 'may': [1534, 1566, 2765, 2794, 2842, 3073, 3215, 3338, 3442, 3681], 'direct': [1535], 'preference': [1541], 'organelles': [1544], 'addition,': [1564], 'rapidly': [1567], 'inactivate': [1568], 'undergoes': [1587], 'proteolytic': [1588], 'degradation': [1589], '(27Granot': [1592], 'Silverman': [1594], 'Friedlander': [1596], 'R.': [1597, 1603, 1647, 1785, 2636, 3043, 3065, 3132, 3638], 'Melamed-Book': [1598], 'Eimerl': [1600], 'Timberg': [1602], 'Hales': [1604, 1606], 'K.H.': [1605], 'D.B.': [1607], 'Orly': [1610], '28:': [1615, 1654, 1792], '375-386Crossref': [1616], '(33)': [1619], '—MLN64': [1623], 'cloned': [1625], 'gene': [1628], 'amplified': [1629], 'breast,': [1631], 'gastric,': [1632], 'esophageal': [1634], 'cancers': [1635], '(28Tomasetto': [1636, 1774], 'Regnier': [1638, 1701, 1776, 1860], 'Moog-Lutz': [1640, 1730, 1778, 1807, 1961, 2021, 2180, 2235], 'Mattei': [1642, 1780], 'M.G.': [1643, 1781], 'Chenard': [1644, 1709, 1782, 1868, 2126, 2382], 'M.P.': [1645, 1710, 1783, 1869, 2127, 2383], 'Lidereau': [1646, 1784], 'Basset': [1648, 1711, 1786, 1870], 'Rio': [1650, 1713, 1738, 1788, 1815, 1872, 1969, 2029, 2134, 2188, 2243, 2390, 2549], 'M.C.': [1651, 1714, 1739, 1789, 1816, 1873, 1970, 1996, 2030, 2135, 2189, 2244, 2391, 4330], 'Genomics.': [1652, 1790], '367-376Crossref': [1655, 1793], '(228)': [1658, 1796], '29Akiyama': [1661], 'Sasaki': [1663], 'Ishizuka': [1665], 'Kishi': [1667], 'Sakamoto': [1669, 4408, 4457], 'Onda': [1671], 'Hirai': [1673], 'Yazaki': [1675], 'Sugimura': [1677], 'Terada': [1679], 'Cancer': [1681], '57:': [1684], '3548-3553PubMed': [1685], 'Although': [1688], 'play': [1691, 3288, 3683], 'causative': [1693, 2294], 'role': [1694, 3685], 'tumorigenesis': [1696], '(30Moog-Lutz': [1697, 1856], 'Tomasetto': [1699, 1734, 1811, 1858, 1965, 2025, 2132, 2184, 2239, 2388, 2551], 'C.H.': [1702, 1861], 'Wendling': [1703, 1862, 2124, 2380, 2547], 'Lutz': [1705, 1864], 'Muller': [1707, 1866], 'Int.': [1715, 1874], 'Cancer.': [1717, 1876], '71:': [1719, 1878], '183-191Crossref': [1720, 1879], '(117)': [1723, 1882], '31Watari': [1726], 'Arakane': [1728, 1805, 1959, 2019, 2178, 2233], 'Gerton': [1736, 1813, 1967, 2027, 2186, 2241], 'G.L.': [1737, 1814, 1968, 2028, 2187, 2242], 'Baker': [1740, 1817, 1971, 2031, 2190, 2245], 'M.E.': [1741, 1818, 1972, 2032, 2119, 2191, 2246, 2375], '94:': [1753, 1830, 1984, 2044, 2203, 2258], '8462-8467Crossref': [1754, 1831, 1985, 2045, 2204, 2259], '(205)': [1757, 1834, 1988, 2048, 2207, 2262], 'amplification': [1760], 'reflects': [1762], 'close': [1763], 'genomic': [1764], 'proximity': [1765], '(within': [1766], '36': [1767], 'kb)': [1768], 'oncogene': [1771], 'c-erb-B2': [1772], '(her-2/neu)': [1773], 'invariantly': [1801], 'co-amplified': [1802], '(31Watari': [1803, 1957, 2017, 2176, 2231], 'terminus': [1839, 3967, 4069], 'includes': [1842], 'four': [1843], 'transmembrane': [1844, 2063, 2328, 2462, 2538], 'helices,': [1845], '37%': [1852], 'identical': [1853, 2534, 3427], 'Like': [1885, 2700], 'binds': [1892, 3959], '(32Zhang': [1910, 2079, 2335, 2479], 'Dwyer': [1914, 2083, 2339, 2483], 'N.K.': [1915, 2084, 2340, 2484], 'Christenson': [1916, 2085, 2303, 2341, 2435, 2485], 'L.K.': [1917, 2086, 2304, 2342, 2436, 2486], 'Fujimoto': [1918, 2087, 2343, 2487], 'Martinez': [1920, 2089, 2345, 2489], 'Comly': [1922, 2091, 2347, 2491], 'Hanover': [1924, 2093, 2349, 2493], 'Blanchette-Mackie': [1926, 2095, 2351, 2495], 'E.J.': [1927, 2096, 2352, 2496], '33300-33310Abstract': [1936, 2105, 2361, 2505], '(133)': [1944, 2113, 2369, 2513], 'vitro': [1949], 'stimulates': [1951], 'when': [1953], 'co-transfected': [1954], '33Bose': [1991], 'Whittal': [1993], 'Huang': [1995], 'Baldwin': [1997], '11722-11731Crossref': [2004], '(82)': [2007], 'detected': [2013, 4395], 'all': [2015, 3259], 'it': [2052, 2068, 3072, 3479, 3510], 'candidate': [2055], 'StAR-independent': [2057], 'placenta.': [2060], 'localizes': [2067], 'late': [2070, 2289], 'endosomes': [2071, 2272, 2478], '34Alpy': [2116, 2372], 'Stoeckel': [2118, 2374], 'Dierich': [2120, 2376], 'Escola': [2122, 2378], 'Vanier': [2128, 2384], 'M.T.': [2129, 2385], 'Gruenberg': [2130, 2386], '4261-4269Abstract': [2141, 2397], '(144)': [2149, 2405], 'Given': [2152], 'relatively': [2158], 'assays,': [2162], 'proteolysis': [2164], 'release': [2166], 'allowing': [2170], 'Supporting': [2210], 'notion,': [2212], 'antibodies': [2213], 'against': [2214], 'prominent': [2223], 'smaller': [2224], 'bands': [2225], 'transfected': [2229], 'also': [2266, 2766, 2969, 3443, 3682], 'functions': [2267], 'mobilization': [2270], 'via': [2273, 3690, 4246], '(NPC)': [2277], 'pathway.': [2278], 'NPC': [2280, 2455, 2471], 'disease': [2281], 'low': [2282, 3622, 4352], 'density': [2283, 3700], 'lipoprotein-derived': [2284], 'accumulates': [2286], 'endosome/lysosome': [2290], 'compartment,': [2291], '(35Strauss': [2299, 2431], 'Steroids.': [2307, 2439], '67:': [2309, 2441], '947-951Crossref': [2310, 2442], '(36)': [2313, 2445], 'NPC2': [2316, 2416], 'soluble': [2319, 2913], 'endosomal': [2320, 2327, 2530], 'cholesterol-binding': [2321], 'NPC1': [2324, 2418], 'efflux': [2329, 3689, 3703], 'pump': [2330], 'co-localizes': [2332], 'Endosomal': [2408], 'thus': [2411], 'move': [2412], 'sequentially': [2413], 'luminal': [2415], 'through': [2417], 'finally': [2422], '1)': [2430], 'mutations': [2449], 'disease,': [2456], 'overexpression': [2458, 2522], 'no': [2465, 3782, 4360], 'phenocopy': [2472], 'accumulation': [2475], 'enlarged': [2477], 'similar': [2517, 3429, 3912], 'phenotype': [2518], 'observed': [2520], 'MENTHO': [2524], '(MLN64': [2525], 'homologue),': [2528], '70%': [2533], 'without': [2541, 4262], '(36Alpy': [2545], 'M.-C.': [2550], '50780-50787Abstract': [2558], '(48)': [2566], 'StarD5': [2571, 2627, 2764, 3123, 3214], '30%': [2573], 'amino': [2574], 'identity': [2576], 'highest': [2584, 3561], 'kidney': [2589, 4400], 'co-transfection': [2619], 'assay': [2620], 'StAR-like': [2622], 'activity,': [2623, 4438], 'stimulate': [2629], 'P450scc.': [2633], '2R.': [2634, 3041, 3063, 3130], 'Soccio,': [2635, 3042, 3064, 3131, 3271], 'Adams,': [2637, 3044, 3066, 3133], 'Breslow,': [2640, 3047, 3069, 3136, 3273], 'unpublished': [2641, 3048, 3070, 3137, 3277], 'data.': [2642, 3049, 3071, 3138, 3278], 'Because': [2643, 3050], 'they': [2644], 'widely': [2646, 3558, 3916], 'expressed,': [2647], 'roles': [2649, 3290, 4253, 4323], 'non-vesicular': [2651], 'transport': [2654, 2891, 3074, 3212], 'proposed': [2657, 3589], '37Maxfield': [2685], 'F.R.': [2686, 3196], 'Wustner': [2687, 3197], '891-898Crossref': [2694, 3204], '(281)': [2697, 3207], '(38Sugawara': [2702], 'Martin': [2708], 'K.O.': [2709], 'Javitt': [2710], 'N.B.': [2711], '34:': [2719], '12506-12512Crossref': [2720], '(197)': [2723], '39Pandak': [2726], 'W.M.': [2727, 2803], 'Ren': [2728, 2804], 'Marques': [2730, 2806], 'Hall': [2732, 2808], 'Redford': [2734, 2810], 'Mallonee': [2736, 2812], 'Bohdan': [2738, 2814], 'Heuman': [2740, 2816], 'Gil': [2742, 2818], 'G.': [2743, 2819, 2862], 'Hylemon': [2744, 2820], '48158-48164Abstract': [2751, 2827], '(99)': [2759, 2835], 'deliver': [2767], 'Cyp27,': [2771], 'generates': [2773], '27-hydroxycholesterol': [2774, 2841], '3).': [2778], 'liver,': [2780, 3813], 'initial': [2784], 'alternative': [2787], 'bile': [2788, 3597], 'synthesis,': [2790, 3062], 'process': [2792, 3082], 'rate-limited': [2796], '(39Pandak': [2802], 'peripheral': [2839], 'cells,': [2840], 'function': [2843, 3145, 3586], 'agonist': [2846], 'X': [2850], 'receptor': [2851], '(LXR)': [2852], 'nuclear': [2853], 'receptors': [2854, 4316], '(40Fu': [2855], 'X.': [2856], 'Menke': [2857], 'Chen': [2859], 'Zhou': [2861], 'MacNaul': [2863], 'Wright': [2865], 'Sparrow': [2867], 'Lund': [2869], 'E.G.': [2870], '38378-38387Abstract': [2876], '(453)': [2884], 'activate': [2888], 'reverse': [2889], '(41Tall': [2892, 3711], 'A.R.': [2893, 3712], 'Costet': [2894, 3713], 'Wang': [2896, 3715], '899-904Crossref': [2903, 3722], '(188)': [2906, 3725], 'more': [2912, 4109], 'oxysterol': [2914], 'leave': [2917], 'directly.': [2919], '—StarD4': [2921], 'microarrays,': [2925], 'hepatic': [2927, 4422], 'decreased': [2931], '2–3-fold': [2932], 'high': [2935, 3331, 3699, 4346], 'diet': [2937, 4436], 'sterol-regulated': [2970], 'cultured': [2972, 3128], 'consistent': [3001], 'transcriptional': [3003], 'regulation': [3004], 'element': [3008], '(SRE)-binding': [3009], '(SREBPs)': [3011], '(42Horton': [3012], 'Goldstein': [3014], 'Brown': [3016], 'M.S.': [3017], '109:': [3022], '1125-1131Crossref': [3023], '(3838)': [3026], 'Reporter': [3029], 'functional': [3035], 'SRE': [3036], 'promoter.': [3040], 'coordinately': [3053], 'regulated': [3054, 3113, 4312, 4425], 'SREBP2': [3056], 'involved': [3059], 'precursor': [3077], 'StarD5—StarD5': [3110], 'sterols,': [3115], 'ER': [3117, 3144, 3155, 3183, 3218], 'stress': [3118, 3156], 'various': [3120], 'agents': [3121], 'activates': [3122, 3152], 'over': [3125, 3787], '6-fold': [3126], 'cells.': [3129, 3269], 'Cells': [3139], 'respond': [3140], 'perturbations': [3142], 'response,': [3150], 'transcription': [3153], 'response': [3157], '(43Harding': [3159], 'H.P.': [3160], 'Calfon': [3161], 'Urano': [3163], 'Novoa': [3165], 'I.': [3166], 'Ron': [3167], 'Cell': [3171, 3546], 'Dev.': [3172], '18:': [3175], '575-599Crossref': [3176], '(812)': [3179], 'sterol-poor': [3186], 'despite': [3188], '(37Maxfield': [3195], 'so': [3210], 'help': [3216], 'reduce': [3217], 'stress.': [3219], 'StarD6': [3220, 3279], '—StarD6': [3221], 'limited': [3224], 'testis': [3227, 3864], 'germ': [3256, 3292, 3869], 'developmental': [3260], 'stages,': [3261], 'somatic': [3265, 3872], 'Leydig': [3266], 'Sertoli': [3268], '3R.': [3270], 'Morris,': [3276], 'important': [3282], 'male': [3284], 'fertility': [3285], 'key': [3289, 3456], 'meiosis': [3295], '(44Byskov': [3296], 'A.G.': [3297], 'Baltsen': [3298], 'Andersen': [3300], 'C.Y.': [3301], '76:': [3306], '818-823Crossref': [3307], '(42)': [3310], 'capacitation': [3314], '(45Travis': [3315], 'A.J.': [3316], 'Kopf': [3317], 'G.S.': [3318], '731-736Crossref': [3324], '(194)': [3327], 'concentrations': [3332], 'desmosterol': [3334], 'sperm': [3336], 'tails': [3337], 'motility': [3340], '(46Connor': [3341], 'W.E.': [3342], 'Wolf': [3345], 'D.P.': [3346], 'Alexander': [3347], 'Lipid': [3350, 4334], '1404-1411Abstract': [3354], 'Unlike': [3363], 'subfamilies,': [3366], 'StarD7,': [3368, 3431, 3785], 'StarD10,': [3369], '(GPBP)': [3374], 'do': [3375], 'common': [3379], 'exonic': [3380], 'organization': [3381], 'homology': [3383, 3923], 'outside': [3384], 'domain.': [3387, 4296], '28': [3392], 'residues': [3393, 3457], 'contact': [3398], '20': [3423], 'these': [3425, 3455], '9': [3433], '11': [3436, 3464], 'aromatics.': [3437], 'This': [3438], 'suggests': [3439], 'StarD7': [3441], 'bind': [3444], 'StarD10': [3447, 3803, 3865], 'GPBP': [3449, 3918, 3958, 4015, 4051, 4114, 4239, 4257], 'exhibit': [3450], 'much': [3451], 'less': [3452], 'similarity': [3453], '(only': [3458], '1': [3459], '3': [3461], 'aromatics': [3465], 'conserved,': [3466], 'respectively),': [3467], 'different': [3469], 'ligands.': [3470], 'PCTP—PCTP': [3471], 'extremely': [3474], 'specific': [3475], 'promotes': [3480], 'intermembrane': [3481], 'phospholipids': [3488, 3705], '(47Wirtz': [3491], 'K.W.': [3492, 3544, 3660], '1991;': [3496], '60:': [3497], '73-99Crossref': [3498], '(380)': [3501], 'relocates': [3511], 'clofibrate': [3515], 'treatment': [3516], 'some': [3518], 'types,': [3520], 'movement': [3523], 'requires': [3524], 'putative': [3526], 'serine': [3530], '110': [3531], '(48de': [3532], 'Brouwer': [3533, 3635], 'Westerman': [3535], 'Kleinnijenhuis': [3537], 'Bevers': [3539], 'L.E.': [3540], 'Roelofsen': [3541], 'B.': [3542, 4141, 4216], 'Wirtz': [3543, 3659], 'Exp.': [3545], '274:': [3549, 3946, 3994, 4039, 4082], '100-111Crossref': [3550], '(26)': [3553], '(49Cohen': [3565], 'Green': [3567], 'Wu': [3569], 'M.K.': [3570], 'Beier': [3571], 'D.R.': [3572], 'Biochim.': [3573], 'Biophys.': [3574], 'Acta.': [3575], '1447:': [3577], '265-270Crossref': [3578], '(27)': [3581], 'selective': [3592], 'secretion': [3593], '5).': [3601], 'were': [3606], 'biliary': [3610], 'levels,': [3612], 'even': [3614, 4270], 'wild-type': [3615], 'adults': [3616], 'study': [3619], 'had': [3620], 'very': [3621], 'compared': [3627], 'newborn': [3629], 'pups': [3630], '(50van': [3631], 'Helvoort': [3632], 'de': [3634], 'Ottenhoff': [3637], 'Brouwers': [3639], 'Wijnholds': [3641], 'Beijnen': [3643], 'Rijneveld': [3645], 'van': [3647, 3651], 'der': [3648, 3652], 'Poll': [3649], 'Valk': [3653], 'Majoor': [3655], 'Voorhout': [3657], 'W.': [3658], 'Elferink': [3661], 'R.P.': [3662], 'Borst': [3663], '96:': [3673], '11501-11506Crossref': [3674], '(65)': [3677, 4161, 4236], 'cellular': [3687], 'ATP': [3691], 'cassette': [3693], 'A1': [3694], '(ABCA1),': [3695], 'plasma': [3698, 3744], 'lipoproteins': [3701], 'apolipoprotein': [3709], 'AI': [3710], 'Overexpression': [3728], 'dose-dependent': [3734], 'acceleration': [3735], 'efflux,': [3738], 'replenishes': [3742], 'PCs': [3747], 'removed': [3751], 'ABCA1': [3753], '4)': [3757], '(51Baez': [3758], 'Barbour': [3760], '6198-6206Abstract': [3769], '(22)': [3777], 'StarD7—There': [3780], 'publications': [3783], '700': [3788], 'clones': [3793], '(ESTs)': [3794], 'many': [3796, 3861], 'indicate': [3798], 'abundant': [3799, 4122], 'widespread': [3801], 'expression.': [3802], '—StarD10': [3804], 'detectable': [3807], 'Northern': [3809], 'blot': [3810], 'testis,': [3812], 'kidney,': [3814], 'intestine': [3816], '(52Yamanaka': [3817, 3874], 'Koga': [3819, 3876], 'Tanaka': [3821, 3878], 'Nakamura': [3823, 3880], 'Ohta': [3825, 3882], 'Yomogida': [3827, 3884], 'Tsuchida': [3829, 3886], 'Iguchi': [3831, 3888], 'Nojima': [3833, 3890], 'Nozaki': [3835, 3892], 'Matsumiya': [3837, 3894], 'Okuyama': [3839, 3896], 'Toshimori': [3841, 3898], 'Nishimune': [3843, 3900], 'Reprod.': [3846, 3903], '62:': [3848, 3905], '1694-1701Crossref': [3849, 3906], '(20)': [3852, 3909], '∼700': [3858], 'ESTs': [3859], 'tissues.': [3862], 'StarD6.': [3914], 'GPBP—The': [3915], '(PH)': [3924], 'domain,': [3925, 4057], 'serine-rich': [3927, 4019, 4128], 'domains,': [3928], '(53Raya': [3934, 3982, 4027, 4070], 'Revert': [3936, 3984, 4029, 4072], 'Navarro': [3938, 3986, 4031, 4074, 4136, 4211], 'Saus': [3940, 3988, 4033, 4076, 4146, 4221], '12642-12649Abstract': [3947, 3995, 4040, 4083], '(75)': [3955, 4003, 4048, 4091], 'phosphorylates': [3961], '(GP)': [3963], 'antigen,': [3964, 4250], 'collagen': [3970, 4267], 'IV': [3971, 4268], 'α3,': [3972], 'autoantibodies': [3978], 'GP': [3980, 4025, 4189, 4249, 4264], 'syndrome': [3981], 'PH': [4006, 4016], 'mediate': [4008], 'protein:protein': [4009], 'protein:membrane': [4011], 'interactions,': [4012], 'first': [4018], 'sufficient': [4022], 'antigen': [4026, 4265], 'conventional': [4054], 'serine/threonine': [4055], 'kinase': [4056, 4098], 'absent': [4061], 'truncated': [4064], 'missing': [4066], 'location': [4095], 'active': [4099], 'known,': [4103], 'than': [4112], 'catalytic.': [4113], 'alternatively': [4117], 'spliced,': [4118], '(GPBPΔ26)': [4124], 'second': [4127], '(54Raya': [4130, 4205], 'Revert-Ros': [4132, 4207], 'Martinez-Martinez': [4134, 4209], 'Rosello': [4138, 4213], 'Vieites': [4140, 4215], 'Granero': [4142, 4217], 'Forteza': [4144, 4219], '275:': [4152, 4227], '40392-40399Abstract': [4153, 4228], 'Antibodies': [4164], 'recognize': [4166], 'rarer': [4168], 'GPBPΔ26': [4173], 'stain': [4174], 'endothelial': [4175], 'basement': [4176], 'membranes': [4177], '(particularly': [4178], 'renal': [4180], 'glomeruli': [4181], 'lung': [4183], 'alveoli,': [4184], 'affected': [4187], 'syndrome)': [4190], 'show': [4192], 'markedly': [4193], 'increased': [4194], 'staining': [4195], 'skin': [4197], 'biopsies': [4198], 'patients': [4200], 'dermatologic': [4202], 'autoimmune': [4203, 4244], 'conditions': [4204], 'diseases': [4245], 'association': [4247], 'conserved': [4259], 'mammals': [4261], 'Drosophila': [4272], 'Caenorhabditis': [4274], 'elegans.': [4275], 'Cytosolic': [4276], 'hydrolase': [4278, 4347], '(CACH)': [4279], 'adipose-associated': [4282], '(THEA)': [4283], 'type': [4287], 'II': [4288], 'acyl-CoA': [4289, 4301], 'Multiple': [4297], 'subcellular': [4298], 'compartments': [4299], 'thioesterases,': [4302], 'hydrolyze': [4304], 'acyl-CoAs': [4305, 4357, 4369], 'free': [4307], 'acids.': [4309], 'Several': [4310], 'peroxisome': [4314], 'proliferator-activated': [4315], 'nutritional': [4318], 'factors,': [4319], 'yet': [4320], 'their': [4321], 'precise': [4322], 'metabolism': [4326], 'remain': [4327], 'undefined': [4328], '(55Hunt': [4329], 'Alexson': [4331], 'Prog.': [4333], '41:': [4337], '99-130Crossref': [4338], '(220)': [4341], 'CACH—CACH': [4344], '(C2),': [4351], 'short': [4355], '(C4–C6),': [4358], 'medium': [4363], '(C12)': [4364], 'long': [4366], '(C16)': [4367], '(56Suematsu': [4370], 'Okamoto': [4372], 'Shibata': [4374], 'Nakanishi': [4376, 4406, 4455], 'Isohashi': [4378, 4404, 4453], 'Eur.': [4380, 4410], '268:': [4384], '2700-2709Crossref': [4385], '(25)': [4388], 'Rat': [4391], 'CACH': [4392, 4441], '(57Matsunaga': [4402, 4451], '1985;': [4413], '152:': [4414], '331-336Crossref': [4415], '(24)': [4418], 'several': [4427], 'metabolic': [4428], 'states.': [4429], 'First,': [4430], 'starvation': [4432], 'fat-free': [4435], 'increase': [4437], 'regulates': [4442], 'oxidation': [4448], 'Eu': [4459]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2011920905', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 13}, {'year': 2020, 'cited_by_count': 14}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 16}, {'year': 2014, 'cited_by_count': 14}, {'year': 2013, 'cited_by_count': 21}, {'year': 2012, 'cited_by_count': 16}], 'updated_date': '2024-12-21T11:47:30.483361', 'created_date': '2016-06-24'}
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